ATE448782T1 - Pharmazeutische glutathionpräparate und methoden zu dern verabreichung - Google Patents
Pharmazeutische glutathionpräparate und methoden zu dern verabreichungInfo
- Publication number
- ATE448782T1 ATE448782T1 AT97952640T AT97952640T ATE448782T1 AT E448782 T1 ATE448782 T1 AT E448782T1 AT 97952640 T AT97952640 T AT 97952640T AT 97952640 T AT97952640 T AT 97952640T AT E448782 T1 ATE448782 T1 AT E448782T1
- Authority
- AT
- Austria
- Prior art keywords
- glutathione
- pharmaceutical
- methods
- administration
- administration same
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
- A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A61K38/063—Glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Gastroenterology & Hepatology (AREA)
- Gynecology & Obstetrics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3410196P | 1996-12-31 | 1996-12-31 | |
| PCT/US1997/023879 WO1998029101A1 (en) | 1996-12-31 | 1997-12-31 | Pharmaceutical preparations of glutathione and methods of administration thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE448782T1 true ATE448782T1 (de) | 2009-12-15 |
Family
ID=21874315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97952640T ATE448782T1 (de) | 1996-12-31 | 1997-12-31 | Pharmazeutische glutathionpräparate und methoden zu dern verabreichung |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US6159500A (de) |
| EP (1) | EP0957901B1 (de) |
| JP (1) | JP2001507696A (de) |
| AT (1) | ATE448782T1 (de) |
| AU (1) | AU5620598A (de) |
| CA (2) | CA2276183C (de) |
| DE (1) | DE69739663D1 (de) |
| WO (1) | WO1998029101A1 (de) |
Families Citing this family (117)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744593A (en) * | 1996-02-15 | 1998-04-28 | Heska Corporation | Parasitic helminth larval thiol specific antioxidant proteins and nucleic acid molecules |
| US6369106B1 (en) * | 1996-12-26 | 2002-04-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Treatment of ischemic brain injuries with brain targeted anti oxidant compounds |
| US6896899B2 (en) * | 1996-12-31 | 2005-05-24 | Antioxidant Pharmaceuticals Corp. | Pharmaceutical preparations of glutathione and methods of administration thereof |
| US20040072138A1 (en) * | 1997-11-25 | 2004-04-15 | Medical University Of South Carolina | Attenuation of ischemia/reperfusion injury |
| WO1999026657A1 (en) * | 1997-11-25 | 1999-06-03 | Musc Foundation For Research Development | Inhibitors of nitric oxide synthase |
| US20080275104A1 (en) * | 1997-11-25 | 2008-11-06 | Musc Foundation For Research Development | Methods of treating juvenile type 1 diabetes mellitus |
| DE69826521T2 (de) * | 1998-01-06 | 2005-09-29 | Cerus Corp., Concord | Verfahren zum quenchen von pathogen-inaktivatoren in biologischen materialien |
| US6312734B1 (en) * | 1998-11-23 | 2001-11-06 | Novelos Therapeutics, Inc. | Methods for production of the oxidized glutathione composite with cis-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells |
| US20070142267A1 (en) * | 1998-11-23 | 2007-06-21 | Novelos Therapeutics, Inc. | Methods for production of the oxidized glutathione composite with CIS-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells |
| RU2144374C1 (ru) * | 1998-11-23 | 2000-01-20 | Закрытое акционерное общество "ВАМ" | Способ получения композита окисленного глутатиона с cis-диаминодихлорплатиной и фармацевтических композиций на его основе, регулирующих метаболизм, пролиферацию, дифференцировку и механизмы апоптоза нормальных и трансформированных клеток |
| GB2367489B (en) * | 2000-07-31 | 2005-02-09 | Mars Inc | Use of antioxidants |
| US6413999B1 (en) | 1999-08-17 | 2002-07-02 | University Of Saskatchewan Technologies Inc. | Treatment for acute physical insult to the central nervous system |
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| WO2001068069A2 (en) * | 2000-03-15 | 2001-09-20 | King's College London | Pharmaceutical composition comprising paracetamol |
| AU2001247762A1 (en) * | 2000-03-28 | 2001-10-08 | Delorenzo, Robert, J | Inhibition of a novel calcium injury current that forms in neurons during injury prevents neuronal cell death |
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| AU2001294808A1 (en) * | 2000-09-29 | 2002-04-08 | Board Of Trustees Operating Michigan State University | Catecholamine pharmaceutical compositions and methods |
| US7179791B2 (en) * | 2001-01-11 | 2007-02-20 | Duke University | Inhibiting GS-FDH to modulate NO bioactivity |
| US20020169112A1 (en) * | 2001-05-08 | 2002-11-14 | Luc Montagnier | Combined treatments and methods for treatment of mycoplasma and mycoplasma-like organism infections |
| US20030096770A1 (en) * | 2001-07-11 | 2003-05-22 | Krotz Achim H. | Enhancement of the stability of oligonucleotides comprising phosphorothioate linkages by addition of water-soluble antioxidants |
| GB2381704B (en) * | 2001-09-14 | 2004-06-30 | Roke Manor Research | A tag and tagging system |
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| EP1435964B1 (de) * | 2001-10-16 | 2009-12-09 | The University of Kansas | Neue prodrugs von n-h-bindung enthaltenden verbindungen und verfahren zu ihrer herstellung |
| US20040241256A1 (en) * | 2002-12-05 | 2004-12-02 | Seymour Ehrenpreis | Medicinal compositions & therapeutic methods |
| EP2138170A3 (de) | 2001-12-18 | 2010-06-23 | Brassica Foundation for Chemoprotection Research, Inc. | Vorbeugung und Behandlung von oxidativen Stress-Erkrankungen mit Verbindungen, die den intrazellulären Spiegel von Glutathion oder Phase-II-Entgiftungsenzymen erhöhen |
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| US20030194453A1 (en) * | 2002-04-15 | 2003-10-16 | Coleman Henry D. | Dietary supplement |
| US20090011048A1 (en) * | 2002-04-16 | 2009-01-08 | Coleman Henry D | Dietary Supplement For Promoting Removal Of Heavy Metals From The Body |
| US20050255129A1 (en) * | 2002-05-03 | 2005-11-17 | Luc Montagnier | Treatments and methods for treatment, diagnosis and prophylaxis |
| US20100316700A1 (en) * | 2002-11-07 | 2010-12-16 | Guilford F Timothy | Systemic administration of liposomal reduced glutathione for the decorporation of radioactive materials and non-radioactive mercury |
| US20070065497A1 (en) * | 2005-09-20 | 2007-03-22 | Guilford Frederick T | Combination and method using EDTA combined with glutathione in the reduced state encapsulated in a liposome to facilitate the method of delivery of the combination as an oral, topical, intraoral or transmucosal, for anti-thrombin effect and for anti-platelet aggregation and measurement of efficacy |
| US20040219600A1 (en) * | 2002-12-13 | 2004-11-04 | Williams Robert Wood | Method for determining sensitivity to environmental toxins and susceptibility to parkinson's disease |
| US20040229815A1 (en) * | 2003-01-03 | 2004-11-18 | Nagasawa Herbert T. | Methods for reducing oxidative stress in a cell with a sulfhydryl protected glutathione prodrug |
| DE10300222A1 (de) * | 2003-01-03 | 2004-07-15 | MedInnova Gesellschaft für medizinische Innovationen aus akademischer Forschung mbH | Verwendung von Wirksubstanzen zur Prophylaxe und/oder Therapie von Viruserkrankungen |
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| US8076060B2 (en) * | 2003-08-04 | 2011-12-13 | Emil William Chynn | Vaccination and immunotherapy as new therapeutic modalities in the treatment of glaucoma |
| JP2005104852A (ja) * | 2003-09-29 | 2005-04-21 | Kyowa Hakko Kogyo Co Ltd | モービリウィルス感染症の予防または治療用組成物 |
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| CA2542419C (en) * | 2003-10-15 | 2013-06-04 | Probiodrug Ag | Use of glutamyl cyclase inhibitors in the treatment of familial british dementia and familial danish dementia |
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- 1997-12-31 AU AU56205/98A patent/AU5620598A/en not_active Abandoned
- 1997-12-31 WO PCT/US1997/023879 patent/WO1998029101A1/en not_active Ceased
- 1997-12-31 US US09/002,100 patent/US6159500A/en not_active Expired - Lifetime
- 1997-12-31 EP EP97952640A patent/EP0957901B1/de not_active Expired - Lifetime
- 1997-12-31 CA CA002276183A patent/CA2276183C/en not_active Expired - Fee Related
- 1997-12-31 DE DE69739663T patent/DE69739663D1/de not_active Expired - Fee Related
- 1997-12-31 US US09/331,947 patent/US6350467B1/en not_active Expired - Lifetime
- 1997-12-31 CA CA002650204A patent/CA2650204A1/en not_active Abandoned
- 1997-12-31 JP JP53020698A patent/JP2001507696A/ja active Pending
- 1997-12-31 AT AT97952640T patent/ATE448782T1/de not_active IP Right Cessation
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1999
- 1999-12-09 US US09/457,642 patent/US6204248B1/en not_active Expired - Lifetime
-
2001
- 2001-03-19 US US09/813,247 patent/US6423687B1/en not_active Expired - Lifetime
-
2002
- 2002-07-22 US US10/200,852 patent/US6586404B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6586404B1 (en) | 2003-07-01 |
| WO1998029101A1 (en) | 1998-07-09 |
| US6159500A (en) | 2000-12-12 |
| DE69739663D1 (de) | 2009-12-31 |
| EP0957901B1 (de) | 2009-11-18 |
| CA2276183C (en) | 2009-06-09 |
| EP0957901A4 (de) | 2006-04-12 |
| CA2650204A1 (en) | 1998-07-09 |
| EP0957901A1 (de) | 1999-11-24 |
| US6423687B1 (en) | 2002-07-23 |
| US6350467B1 (en) | 2002-02-26 |
| US6204248B1 (en) | 2001-03-20 |
| AU5620598A (en) | 1998-07-31 |
| CA2276183A1 (en) | 1998-07-09 |
| JP2001507696A (ja) | 2001-06-12 |
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