ATE448812T1 - Beschichtung von stents mit verzögerter wirkstofffreisetzung - Google Patents

Beschichtung von stents mit verzögerter wirkstofffreisetzung

Info

Publication number
ATE448812T1
ATE448812T1 AT03738920T AT03738920T ATE448812T1 AT E448812 T1 ATE448812 T1 AT E448812T1 AT 03738920 T AT03738920 T AT 03738920T AT 03738920 T AT03738920 T AT 03738920T AT E448812 T1 ATE448812 T1 AT E448812T1
Authority
AT
Austria
Prior art keywords
stents
coating
delayed release
coatings
drug
Prior art date
Application number
AT03738920T
Other languages
English (en)
Inventor
Syed Hossainy
Gordon Stewart
Original Assignee
Abbott Cardiovascular Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Cardiovascular Systems filed Critical Abbott Cardiovascular Systems
Application granted granted Critical
Publication of ATE448812T1 publication Critical patent/ATE448812T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/08—Coatings comprising two or more layers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT03738920T 2002-06-21 2003-05-14 Beschichtung von stents mit verzögerter wirkstofffreisetzung ATE448812T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/177,154 US7396539B1 (en) 2002-06-21 2002-06-21 Stent coatings with engineered drug release rate
PCT/US2003/015347 WO2004000379A1 (en) 2002-06-21 2003-05-14 Stent coatings with sustained drug release rate

Publications (1)

Publication Number Publication Date
ATE448812T1 true ATE448812T1 (de) 2009-12-15

Family

ID=29999084

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03738920T ATE448812T1 (de) 2002-06-21 2003-05-14 Beschichtung von stents mit verzögerter wirkstofffreisetzung

Country Status (7)

Country Link
US (2) US7396539B1 (de)
EP (1) EP1517713B1 (de)
JP (1) JP2005530551A (de)
AT (1) ATE448812T1 (de)
AU (1) AU2003245282A1 (de)
DE (1) DE60330144D1 (de)
WO (1) WO2004000379A1 (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030129215A1 (en) * 1998-09-24 2003-07-10 T-Ram, Inc. Medical devices containing rapamycin analogs
GB0100761D0 (en) 2001-01-11 2001-02-21 Biocompatibles Ltd Drug delivery from stents
US6764505B1 (en) 2001-04-12 2004-07-20 Advanced Cardiovascular Systems, Inc. Variable surface area stent
US6656506B1 (en) * 2001-05-09 2003-12-02 Advanced Cardiovascular Systems, Inc. Microparticle coated medical device
US7056338B2 (en) 2003-03-28 2006-06-06 Conor Medsystems, Inc. Therapeutic agent delivery device with controlled therapeutic agent release rates
EP1539270A1 (de) * 2002-09-18 2005-06-15 Medtronic Vascular, Inc. Steuerbare, arznemittelfreisetzende gradientbeschichtungen für medizinische vorrichtungen
US7169178B1 (en) * 2002-11-12 2007-01-30 Advanced Cardiovascular Systems, Inc. Stent with drug coating
US20090093875A1 (en) * 2007-05-01 2009-04-09 Abbott Laboratories Drug eluting stents with prolonged local elution profiles with high local concentrations and low systemic concentrations
US8313759B2 (en) * 2003-03-06 2012-11-20 Boston Scientific Scimed, Inc. Implantable or insertable medical devices containing miscible polymer blends for controlled delivery of a therapeutic agent
US20040215335A1 (en) * 2003-04-25 2004-10-28 Brin David S. Methods and apparatus for treatment of aneurysmal tissue
DE10329260A1 (de) * 2003-06-23 2005-01-13 Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin Stent mit einem Beschichtungssystem
US20050033417A1 (en) * 2003-07-31 2005-02-10 John Borges Coating for controlled release of a therapeutic agent
US7166099B2 (en) * 2003-08-21 2007-01-23 Boston Scientific Scimed, Inc. Multilayer medical devices
DE10357281A1 (de) * 2003-12-05 2005-07-14 Hassel, Thomas, Dipl.-Ing. Gefäßstütze
DE10361940A1 (de) * 2003-12-24 2005-07-28 Restate Patent Ag Degradationssteuerung biodegradierbarer Implantate durch Beschichtung
US8137397B2 (en) * 2004-02-26 2012-03-20 Boston Scientific Scimed, Inc. Medical devices
US20070027523A1 (en) * 2004-03-19 2007-02-01 Toner John L Method of treating vascular disease at a bifurcated vessel using coated balloon
US8431145B2 (en) * 2004-03-19 2013-04-30 Abbott Laboratories Multiple drug delivery from a balloon and a prosthesis
US20050208093A1 (en) 2004-03-22 2005-09-22 Thierry Glauser Phosphoryl choline coating compositions
US8915952B2 (en) 2004-03-31 2014-12-23 Merlin Md Pte Ltd. Method for treating aneurysms
US8500751B2 (en) 2004-03-31 2013-08-06 Merlin Md Pte Ltd Medical device
US9011831B2 (en) 2004-09-30 2015-04-21 Advanced Cardiovascular Systems, Inc. Methacrylate copolymers for medical devices
US20070100321A1 (en) * 2004-12-22 2007-05-03 Leon Rudakov Medical device
KR100511618B1 (ko) * 2005-01-17 2005-08-31 이경범 약물방출 조절형 다층 코팅 스텐트 및 이의 제조방법
EP1879552B1 (de) * 2005-03-14 2016-02-17 Biotegra, Inc. Arzneimittelabgabezusammensetzungen und dazugehörige verfahren
US9381279B2 (en) 2005-03-24 2016-07-05 Abbott Cardiovascular Systems Inc. Implantable devices formed on non-fouling methacrylate or acrylate polymers
US7700659B2 (en) * 2005-03-24 2010-04-20 Advanced Cardiovascular Systems, Inc. Implantable devices formed of non-fouling methacrylate or acrylate polymers
WO2006109590A1 (ja) * 2005-04-05 2006-10-19 National University Corporation Kanazawa University 医療用器具
US20070050009A1 (en) * 2005-08-30 2007-03-01 Aiden Flanagan Bioabsorbable stent
US20070055352A1 (en) * 2005-09-07 2007-03-08 Wendy Naimark Stent with pockets for containing a therapeutic agent
US8003156B2 (en) 2006-05-04 2011-08-23 Advanced Cardiovascular Systems, Inc. Rotatable support elements for stents
US20080095918A1 (en) * 2006-06-14 2008-04-24 Kleiner Lothar W Coating construct with enhanced interfacial compatibility
US20080118541A1 (en) * 2006-11-21 2008-05-22 Abbott Laboratories Use of a terpolymer of tetrafluoroethylene, hexafluoropropylene, and vinylidene fluoride in drug eluting coatings on medical devices
US7713541B1 (en) * 2006-11-21 2010-05-11 Abbott Cardiovascular Systems Inc. Zwitterionic terpolymers, method of making and use on medical devices
JP5557373B2 (ja) * 2006-11-21 2014-07-23 アボット ラボラトリーズ 薬剤溶出性コーティングにおけるテトラフルオロエチレン、ヘキサフルオロプロピレン、及びフッ化ビニリデンのターポリマーの使用
US8017141B2 (en) 2006-12-15 2011-09-13 Advanced Cardiovascular Systems, Inc. Coatings of acrylamide-based copolymers
US8221496B2 (en) 2007-02-01 2012-07-17 Cordis Corporation Antithrombotic and anti-restenotic drug eluting stent
US20080286332A1 (en) 2007-05-14 2008-11-20 Pacetti Stephen D Implantable medical devices with a topcoat layer of phosphoryl choline acrylate polymer for reduced thrombosis, and improved mechanical properties
US8367150B2 (en) * 2007-06-15 2013-02-05 Abbott Cardiovascular Systems Inc. Methods and apparatus for coating stents
US9737638B2 (en) 2007-06-20 2017-08-22 Abbott Cardiovascular Systems, Inc. Polyester amide copolymers having free carboxylic acid pendant groups
US20090004243A1 (en) 2007-06-29 2009-01-01 Pacetti Stephen D Biodegradable triblock copolymers for implantable devices
DE102007034364A1 (de) * 2007-07-24 2009-01-29 Biotronik Vi Patent Ag Degradierbarer Metallstent mit wirkstoffhaltiger Beschichtung
KR20100085179A (ko) * 2007-09-04 2010-07-28 가부시키가이샤 니혼 스텐토 테크놀로지 약제 서방성 스텐트
US8128983B2 (en) * 2008-04-11 2012-03-06 Abbott Cardiovascular Systems Inc. Coating comprising poly(ethylene glycol)-poly(lactide-glycolide-caprolactone) interpenetrating network
US20090285873A1 (en) * 2008-04-18 2009-11-19 Abbott Cardiovascular Systems Inc. Implantable medical devices and coatings therefor comprising block copolymers of poly(ethylene glycol) and a poly(lactide-glycolide)
US8916188B2 (en) * 2008-04-18 2014-12-23 Abbott Cardiovascular Systems Inc. Block copolymer comprising at least one polyester block and a poly (ethylene glycol) block
US20090297584A1 (en) * 2008-04-18 2009-12-03 Florencia Lim Biosoluble coating with linear over time mass loss
US8697113B2 (en) * 2008-05-21 2014-04-15 Abbott Cardiovascular Systems Inc. Coating comprising a terpolymer comprising caprolactone and glycolide
US8709040B2 (en) 2008-06-26 2014-04-29 Vitasynergies, Llc Suture anchor, guide for locating a hole in a bone, and suture anchor delivery tool
DE102008040356A1 (de) * 2008-07-11 2010-01-14 Biotronik Vi Patent Ag Stent mit biodegradierbaren Stentstreben und Wirkstoffdepots
US20100106242A1 (en) * 2008-10-23 2010-04-29 Abbott Cardiovascular Systems Inc. Stent and method for making a stent
DE102008043277A1 (de) * 2008-10-29 2010-05-06 Biotronik Vi Patent Ag Implantat aus einer biokorrodierbaren Eisen- oder Magnesiumlegierung
JP5597625B2 (ja) 2009-03-02 2014-10-01 株式会社日本ステントテクノロジー 薬剤溶出性ステント
US8183337B1 (en) 2009-04-29 2012-05-22 Abbott Cardiovascular Systems Inc. Method of purifying ethylene vinyl alcohol copolymers for use with implantable medical devices
US8697110B2 (en) * 2009-05-14 2014-04-15 Abbott Cardiovascular Systems Inc. Polymers comprising amorphous terpolymers and semicrystalline blocks
US8911766B2 (en) 2009-06-26 2014-12-16 Abbott Cardiovascular Systems Inc. Drug delivery compositions including nanoshells for triggered drug release
US8480620B2 (en) * 2009-12-11 2013-07-09 Abbott Cardiovascular Systems Inc. Coatings with tunable solubility profile for drug-coated balloon
US8951595B2 (en) * 2009-12-11 2015-02-10 Abbott Cardiovascular Systems Inc. Coatings with tunable molecular architecture for drug-coated balloon
US20110144577A1 (en) * 2009-12-11 2011-06-16 John Stankus Hydrophilic coatings with tunable composition for drug coated balloon
EP2338534A2 (de) * 2009-12-21 2011-06-29 Biotronik VI Patent AG Medizinisches Implantat, Beschichtungsverfahren sowie Implantationsverfahren
JP6324371B2 (ja) 2012-04-06 2018-05-16 マーリン エムディー プライベート リミテッド 動脈瘤を治療するためのデバイスおよび方法
US10238513B2 (en) * 2017-07-19 2019-03-26 Abbott Cardiovascular Systems Inc. Intravascular stent

Family Cites Families (237)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1078329B (de) 1955-04-27 1960-03-24 Du Pont Verfahren zur Herstellung eines elastischen Mischpolymerisats aus Vinylidenfluorid und einem anderen Fluorolefin
US2968649A (en) 1958-12-04 1961-01-17 Du Pont Elastomeric terpolymers
US3178399A (en) 1961-08-10 1965-04-13 Minnesota Mining & Mfg Fluorine-containing polymers and preparation thereof
US3324069A (en) 1964-10-23 1967-06-06 Pennsalt Chemicals Corp Vinylidene fluoride polymer dispersions
US3856827A (en) 1970-12-28 1974-12-24 Jefferson Chem Co Inc Silicon containing molybdenum catalysts
US3779805A (en) 1971-05-19 1973-12-18 Bell Telephone Labor Inc Method of making waveguide mode filter
US4076929A (en) 1975-10-30 1978-02-28 Pennwalt Corporation Vinylidene fluoride polymer having improved melt flow properties
US4197380A (en) 1978-03-01 1980-04-08 Raychem Corporation Hot melt adhesive comprising fluorocarbon elastomer, ethylene copolymer and tackifier
US4346710A (en) 1978-06-16 1982-08-31 Pennwalt Corporation Article for storage and transport of biogenic fluids
US4353960A (en) 1978-09-21 1982-10-12 Kureha Kagaku Kogyo Kabushiki Kaisha Composite and conjugate filaments
JPS6037733B2 (ja) 1978-10-12 1985-08-28 住友電気工業株式会社 管状臓器補綴材及びその製造方法
US4423183A (en) 1980-09-16 1983-12-27 David Hudson, Inc. Fluoroelastomer film compositions and solutions containing fatty polyamide curatives
JPS57144756A (en) 1981-03-04 1982-09-07 Koken Kk Impermeable laminated film
US4530569A (en) 1981-08-20 1985-07-23 E. I. Du Pont De Nemours And Company Optical fibers comprising cores clad with amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4977297A (en) 1981-08-20 1990-12-11 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4977026A (en) 1981-08-20 1990-12-11 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US5000547A (en) 1981-08-20 1991-03-19 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4973142A (en) 1981-08-20 1990-11-27 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4948851A (en) 1981-08-20 1990-08-14 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4977008A (en) 1981-08-20 1990-12-11 E. I Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4977025A (en) 1981-08-20 1990-12-11 E. I Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4985308A (en) 1981-08-20 1991-01-15 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US5006382A (en) 1981-08-20 1991-04-09 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4982056A (en) 1981-08-20 1991-01-01 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxide
US4754009A (en) 1981-08-20 1988-06-28 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4935477A (en) 1981-08-20 1990-06-19 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4975505A (en) 1981-08-20 1990-12-04 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4999248A (en) 1981-08-20 1991-03-12 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4485250A (en) 1981-11-19 1984-11-27 E. I. Du Pont De Nemours And Company Perfluorodioxole and its polymers
US4399264A (en) 1981-11-19 1983-08-16 E. I. Du Pont De Nemours & Co. Perfluorodioxole and its polymers
US5051978A (en) 1982-11-30 1991-09-24 Burroughs Corporation Coated media for optical recording
US4636346A (en) 1984-03-08 1987-01-13 Cordis Corporation Preparing guiding catheter
US4564013A (en) 1984-05-24 1986-01-14 Ethicon, Inc. Surgical filaments from vinylidene fluoride copolymers
US4569978A (en) 1984-07-25 1986-02-11 Pennwalt Corporation Emulsion polymerization of vinylidene fluoride polymers in the presence of trichlorofluoromethane as chain transfer agent
US4718907A (en) 1985-06-20 1988-01-12 Atrium Medical Corporation Vascular prosthesis having fluorinated coating with varying F/C ratio
US4632842A (en) 1985-06-20 1986-12-30 Atrium Medical Corporation Glow discharge process for producing implantable devices
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US4871357A (en) 1986-01-21 1989-10-03 Baxter International Inc. Ionic heparin coating
US4749585A (en) 1986-04-11 1988-06-07 University Of Medicine And Dentistry Of New Jersey Antibiotic bonded prosthesis and process for producing same
GB2194539B (en) 1986-09-01 1990-08-01 Labofina Sa Pvdf-based powder coatings
JPS6389138A (ja) 1986-10-03 1988-04-20 オリンパス光学工業株式会社 内視鏡用弯曲管外皮
US4800882A (en) 1987-03-13 1989-01-31 Cook Incorporated Endovascular stent and delivery system
US5100689A (en) 1987-04-10 1992-03-31 University Of Florida Surface modified surgical instruments, devices, implants, contact lenses and the like
US4876109A (en) 1987-04-13 1989-10-24 Cardiac Pacemakers, Inc. Soluble covering for cardiac pacing electrode
US4897457A (en) 1987-08-14 1990-01-30 Asahi Glass Company Ltd. Novel fluorine-containing cyclic polymer
US5047020A (en) 1987-09-14 1991-09-10 Baxter International Inc. Ionic heparin coating
US4886062A (en) 1987-10-19 1989-12-12 Medtronic, Inc. Intravascular radially expandable stent and method of implant
US5185408A (en) 1987-12-17 1993-02-09 Allied-Signal Inc. Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides
US5076659A (en) 1988-05-27 1991-12-31 E. I. Du Pont De Nemours And Company Process for the stabilization of fluoropolymers
US4931287A (en) 1988-06-14 1990-06-05 University Of Utah Heterogeneous interpenetrating polymer networks for the controlled release of drugs
US5444113A (en) 1988-08-08 1995-08-22 Ecopol, Llc End use applications of biodegradable polymers
US4908404A (en) 1988-08-22 1990-03-13 Biopolymers, Inc. Synthetic amino acid-and/or peptide-containing graft copolymers
US5328471A (en) 1990-02-26 1994-07-12 Endoluminal Therapeutics, Inc. Method and apparatus for treatment of focal disease in hollow tubular organs and other tissue lumens
US5053048A (en) 1988-09-22 1991-10-01 Cordis Corporation Thromboresistant coating
US5030394A (en) 1988-11-08 1991-07-09 Labofina, S.A. PVdF-based powder coatings
US4977901A (en) 1988-11-23 1990-12-18 Minnesota Mining And Manufacturing Company Article having non-crosslinked crystallized polymer coatings
JP3027606B2 (ja) 1989-06-15 2000-04-04 デユポン・カナダ・インコーポレーテツド パーフルオロジオキソール膜
US5196404B1 (en) 1989-08-18 1996-09-10 Biogen Inc Inhibitors of thrombin
US5971954A (en) 1990-01-10 1999-10-26 Rochester Medical Corporation Method of making catheter
US5545208A (en) 1990-02-28 1996-08-13 Medtronic, Inc. Intralumenal drug eluting prosthesis
US5107852A (en) 1990-04-02 1992-04-28 W. L. Gore & Associates, Inc. Catheter guidewire device having a covering of fluoropolymer tape
US5093427A (en) 1990-05-10 1992-03-03 Atochem North America, Inc. Copolymers of vinylidene fluoride and hexafluoropropylene and process for preparing the same
US5395311A (en) 1990-05-14 1995-03-07 Andrews; Winston A. Atherectomy catheter
WO1991017724A1 (en) 1990-05-17 1991-11-28 Harbor Medical Devices, Inc. Medical device polymer
US6060451A (en) 1990-06-15 2000-05-09 The National Research Council Of Canada Thrombin inhibitors based on the amino acid sequence of hirudin
US5112457A (en) 1990-07-23 1992-05-12 Case Western Reserve University Process for producing hydroxylated plasma-polymerized films and the use of the films for enhancing the compatiblity of biomedical implants
US5455040A (en) 1990-07-26 1995-10-03 Case Western Reserve University Anticoagulant plasma polymer-modified substrate
US5302385A (en) 1990-08-20 1994-04-12 Becton, Dickinson And Company Polyurethane-polyvinylpyrrolidone block copolymer and iodine carrier therefrom
US5632776A (en) 1990-11-22 1997-05-27 Toray Industries, Inc. Implantation materials
ATE172664T1 (de) 1991-04-15 1998-11-15 Univ Groningen Verfahren zum modifizieren von fluor enthlatendem kunststoffs, modifizierten kunststoff und diesen kunststoff enthaltendes biomaterial
US5246451A (en) 1991-04-30 1993-09-21 Medtronic, Inc. Vascular prosthesis and method
JP3558293B2 (ja) 1991-08-27 2004-08-25 ダイキン工業株式会社 フッ素ゴム塗料組成物
US5176972A (en) 1991-09-11 1993-01-05 Polaroid Corporation Imaging medium with low refractive index layer
WO1993005825A1 (en) 1991-09-20 1993-04-01 Baxter International Inc. Processes for reducing the thrombogenicity of biomaterials
AU2605592A (en) 1991-10-15 1993-04-22 Atrix Laboratories, Inc. Polymeric compositions useful as controlled release implants
JPH05307137A (ja) 1992-01-07 1993-11-19 Olympus Optical Co Ltd レンズ鏡筒
US5296283A (en) 1992-01-13 1994-03-22 E. I. Du Pont De Nemours And Company Protective coating for machine-readable markings
US5573934A (en) 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
US5591224A (en) 1992-03-19 1997-01-07 Medtronic, Inc. Bioelastomeric stent
US5599352A (en) 1992-03-19 1997-02-04 Medtronic, Inc. Method of making a drug eluting stent
SE500972C2 (sv) 1992-03-30 1994-10-10 Moelnlycke Ab Förfarande och anordning för tillverkning av sårförband samt ett sårförband tillverkat medelst förfarandet
CA2094858C (en) 1992-04-28 2004-06-15 Robert D. Mitchell Method of treating hyperproliferative vascular disease
US5368566A (en) 1992-04-29 1994-11-29 Cardiovascular Dynamics, Inc. Delivery and temporary stent catheter having a reinforced perfusion lumen
US5276121A (en) 1992-05-05 1994-01-04 E. I. Du Pont De Nemours And Company Amorphous copolymers of two fluorinated ring monomers
US5383928A (en) 1992-06-10 1995-01-24 Emory University Stent sheath for local drug delivery
WO1994002185A1 (en) 1992-07-20 1994-02-03 Advanced Cardiovascular Systems, Inc. Inflatable member formed of fluoropolymeric material
US5383853A (en) 1992-11-12 1995-01-24 Medtronic, Inc. Rapid exchange catheter
US5342348A (en) 1992-12-04 1994-08-30 Kaplan Aaron V Method and device for treating and enlarging body lumens
US5336518A (en) 1992-12-11 1994-08-09 Cordis Corporation Treatment of metallic surfaces using radiofrequency plasma deposition and chemical attachment of bioactive agents
US5443458A (en) 1992-12-22 1995-08-22 Advanced Cardiovascular Systems, Inc. Multilayered biodegradable stent and method of manufacture
US5824048A (en) 1993-04-26 1998-10-20 Medtronic, Inc. Method for delivering a therapeutic substance to a body lumen
US5464650A (en) 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
JPH07498A (ja) 1993-06-02 1995-01-06 Uchida Yasunari 骨誘導材
US5861168A (en) 1993-06-11 1999-01-19 The Board Of Trustees Of The Leland Stanford Junior University Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury
JPH0767895A (ja) 1993-06-25 1995-03-14 Sumitomo Electric Ind Ltd 抗菌性人工血管及び抗菌性手術用縫合糸
US5886026A (en) 1993-07-19 1999-03-23 Angiotech Pharmaceuticals Inc. Anti-angiogenic compositions and methods of use
EG20321A (en) 1993-07-21 1998-10-31 Otsuka Pharma Co Ltd Medical material and process for producing the same
DE69330132T2 (de) 1993-07-23 2001-11-15 Cook Inc., Bloomington Flexibler stent mit einer aus einem materialbogen geformten konfiguration
EP1118325B2 (de) 1993-07-29 2010-01-06 The United States of America, represented by the Secretary, Department of Health and Human Services Verwendung von Paclitaxel und seinen Derivaten zur Herstellung eines Medikaments für die Behandlung von Restenose
US5380299A (en) 1993-08-30 1995-01-10 Med Institute, Inc. Thrombolytic treated intravascular medical device
US5310838A (en) 1993-09-07 1994-05-10 E. I. Du Pont De Nemours And Company Functional fluoropolymers
US5723004A (en) 1993-10-21 1998-03-03 Corvita Corporation Expandable supportive endoluminal grafts
DE4337613A1 (de) 1993-11-04 1995-05-11 Fichtel & Sachs Ag Reibungskupplung mit automatischem Verschleißausgleich und Spielgeber
DE69428721T2 (de) 1993-12-10 2002-06-20 Schneider (Usa) Inc., Plymouth Führungskatheter
EP0741585A1 (de) 1994-01-21 1996-11-13 Brown University Research Foundation Bioverträgliche implantate
US5403341A (en) 1994-01-24 1995-04-04 Solar; Ronald J. Parallel flow endovascular stent and deployment apparatus therefore
EP0804249A2 (de) 1994-03-15 1997-11-05 Brown University Research Foundation Polymeres system zur freisetzung von genen
JP3129327B2 (ja) 1994-04-01 2001-01-29 プログラフト メディカル，インコーポレイテッド 自己拡張可能なステントおよびステント−グラフトならびにそれらの使用方法
US5408020A (en) 1994-05-09 1995-04-18 E. I. Du Pont De Nemours And Company Copolymers of perhalo-2,2-di-loweralkyl-1,3-dioxole, and perfluoro-2-methylene-4-methyl-1,3-dioxolane
US5670558A (en) 1994-07-07 1997-09-23 Terumo Kabushiki Kaisha Medical instruments that exhibit surface lubricity when wetted
US5656121A (en) 1994-08-19 1997-08-12 Minnesota Mining And Manufacturing Company Method of making multi-layer composites having a fluoropolymer layer
US5578073A (en) 1994-09-16 1996-11-26 Ramot Of Tel Aviv University Thromboresistant surface treatment for biomaterials
US5649977A (en) 1994-09-22 1997-07-22 Advanced Cardiovascular Systems, Inc. Metal reinforced polymer stent
CA2202511A1 (en) * 1994-10-12 1996-04-25 Laurence A. Roth Targeted delivery via biodegradable polymers
TW363075B (en) 1994-11-01 1999-07-01 Daikin Ind Ltd Fluoride polymer compound painting and coating method thereof
US5637113A (en) 1994-12-13 1997-06-10 Advanced Cardiovascular Systems, Inc. Polymer film for wrapping a stent structure
AU4757596A (en) 1995-01-14 1996-07-31 Prograft Medical, Inc. Kink-resistant stent-graft
US6017577A (en) 1995-02-01 2000-01-25 Schneider (Usa) Inc. Slippery, tenaciously adhering hydrophilic polyurethane hydrogel coatings, coated polymer substrate materials, and coated medical devices
US5919570A (en) 1995-02-01 1999-07-06 Schneider Inc. Slippery, tenaciously adhering hydrogel coatings containing a polyurethane-urea polymer hydrogel commingled with a poly(N-vinylpyrrolidone) polymer hydrogel, coated polymer and metal substrate materials, and coated medical devices
US5575818A (en) 1995-02-14 1996-11-19 Corvita Corporation Endovascular stent with locking ring
US5869127A (en) 1995-02-22 1999-02-09 Boston Scientific Corporation Method of providing a substrate with a bio-active/biocompatible coating
US6179817B1 (en) 1995-02-22 2001-01-30 Boston Scientific Corporation Hybrid coating for medical devices
US6147168A (en) 1995-03-06 2000-11-14 Ethicon, Inc. Copolymers of absorbable polyoxaesters
US6264684B1 (en) 1995-03-10 2001-07-24 Impra, Inc., A Subsidiary Of C.R. Bard, Inc. Helically supported graft
US5605696A (en) 1995-03-30 1997-02-25 Advanced Cardiovascular Systems, Inc. Drug loaded polymeric material and method of manufacture
CA2217541A1 (en) 1995-04-07 1996-10-10 Biotec Biologische Naturverpackungen Gmbh Biologically degradable polymer mixture
US6099562A (en) 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US5837313A (en) 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US6120536A (en) 1995-04-19 2000-09-19 Schneider (Usa) Inc. Medical devices with long term non-thrombogenic coatings
US5900425A (en) 1995-05-02 1999-05-04 Bayer Aktiengesellschaft Pharmaceutical preparations having controlled release of active compound and processes for their preparation
US5562734A (en) 1995-05-31 1996-10-08 Zimmer, Inc. Method for reducing gamma radiation sterilization induced discoloration
US5628728A (en) 1995-05-31 1997-05-13 Ekos Corporation Medicine applying tool
US5704910A (en) 1995-06-05 1998-01-06 Nephros Therapeutics, Inc. Implantable device and use therefor
AU716005B2 (en) 1995-06-07 2000-02-17 Cook Medical Technologies Llc Implantable medical device
US6129761A (en) 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
US5609629A (en) * 1995-06-07 1997-03-11 Med Institute, Inc. Coated implantable medical device
US5820917A (en) 1995-06-07 1998-10-13 Medtronic, Inc. Blood-contacting medical device and method
US5750234A (en) 1996-06-07 1998-05-12 Avery Dennison Corporation Interior automotive laminate with thermoplastic low gloss coating
US5667767A (en) 1995-07-27 1997-09-16 Micro Therapeutics, Inc. Compositions for use in embolizing blood vessels
US5804318A (en) 1995-10-26 1998-09-08 Corvita Corporation Lubricious hydrogel surface modification
JP2000503559A (ja) 1995-12-14 2000-03-28 ゴア エンタープライズ ホールディングス，インコーポレイティド ステント移植片を展開する装置並びに方法
US6042605A (en) 1995-12-14 2000-03-28 Gore Enterprose Holdings, Inc. Kink resistant stent-graft
WO1997022371A1 (en) 1995-12-18 1997-06-26 Collagen Corporation Crosslinked polymer compositions and methods for their use
JP3941128B2 (ja) 1995-12-18 2007-07-04 ダイキン工業株式会社 粉体塗料用組成物
US5713949A (en) 1996-08-06 1998-02-03 Jayaraman; Swaminathan Microporous covered stents and method of coating
US5932299A (en) 1996-04-23 1999-08-03 Katoot; Mohammad W. Method for modifying the surface of an object
GB9608882D0 (en) 1996-04-30 1996-07-03 Luthra Ajay K Non-thrombogenic and anti-thrombogenic polymers
US5874165A (en) 1996-06-03 1999-02-23 Gore Enterprise Holdings, Inc. Materials and method for the immobilization of bioactive species onto polymeric subtrates
NL1003497C2 (nl) 1996-07-03 1998-01-07 Cordis Europ Katheter met tijdelijk vena-cava filter.
US5928279A (en) 1996-07-03 1999-07-27 Baxter International Inc. Stented, radially expandable, tubular PTFE grafts
US6060534A (en) 1996-07-11 2000-05-09 Scimed Life Systems, Inc. Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
US5830178A (en) 1996-10-11 1998-11-03 Micro Therapeutics, Inc. Methods for embolizing vascular sites with an emboilizing composition comprising dimethylsulfoxide
WO1998008463A1 (en) 1996-08-30 1998-03-05 Helix Medical Corporation Medical devices having microbial resistant material properties
AUPO251096A0 (en) 1996-09-23 1996-10-17 Cardiac Crc Nominees Pty Limited Polysiloxane-containing polyurethane elastomeric compositions
US6033724A (en) 1996-11-27 2000-03-07 Spalding Sports Worldwide, Inc. Golf ball mold preparation technique and coating system
US6315791B1 (en) 1996-12-03 2001-11-13 Atrium Medical Corporation Self-expanding prothesis
US5980972A (en) 1996-12-20 1999-11-09 Schneider (Usa) Inc Method of applying drug-release coatings
US5997517A (en) 1997-01-27 1999-12-07 Sts Biopolymers, Inc. Bonding layers for medical device surface coatings
AU737252B2 (en) 1997-02-20 2001-08-16 Cook Medical Technologies Llc Coated implantable medical device
US5858990A (en) 1997-03-04 1999-01-12 St. Elizabeth's Medical Center Fas ligand compositions for treatment of proliferative disorders
US6273913B1 (en) 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
US6165166A (en) 1997-04-25 2000-12-26 Schneider (Usa) Inc. Trilayer, extruded medical tubing and medical devices incorporating such tubing
US5879697A (en) 1997-04-30 1999-03-09 Schneider Usa Inc Drug-releasing coatings for medical devices
DE19723723C2 (de) 1997-05-30 1999-05-20 Fraunhofer Ges Forschung Polymerbeschichtung für Prothesen, Implantate und Körperelektroden und Verfahren zu ihrer Herstellung
US6056993A (en) 1997-05-30 2000-05-02 Schneider (Usa) Inc. Porous protheses and methods for making the same wherein the protheses are formed by spraying water soluble and water insoluble fibers onto a rotating mandrel
WO1998057671A2 (en) 1997-06-18 1998-12-23 Boston Scientific Corporation Polycarbonate-polyurethane dispersions for thrombo-resistant coatings
US6110483A (en) 1997-06-23 2000-08-29 Sts Biopolymers, Inc. Adherent, flexible hydrogel and medicated coatings
CA2294872A1 (en) 1997-06-24 1998-12-30 Schering Aktiengesellschaft Stents that are coated with fluoroalkyl groups, processes for their production and their use for restenosis prophylaxis
US5980928A (en) 1997-07-29 1999-11-09 Terry; Paul B. Implant for preventing conjunctivitis in cattle
US5897911A (en) 1997-08-11 1999-04-27 Advanced Cardiovascular Systems, Inc. Polymer-coated stent structure
US6121027A (en) 1997-08-15 2000-09-19 Surmodics, Inc. Polybifunctional reagent having a polymeric backbone and photoreactive moieties and bioactive groups
US6890546B2 (en) 1998-09-24 2005-05-10 Abbott Laboratories Medical devices containing rapamycin analogs
US6015541A (en) 1997-11-03 2000-01-18 Micro Therapeutics, Inc. Radioactive embolizing compositions
WO1999024174A1 (en) 1997-11-10 1999-05-20 Katoot Mohammad W Method for modifying the surface of an object
US6096396A (en) 1998-01-21 2000-08-01 Rexam Industries Corp. Decorative sheet material suitable for use as a flexible weatherable paint film or decal
DE69918607T2 (de) 1998-03-05 2005-07-21 Solvay Solexis, Inc., Wilmington Witterungsbeständige Beschichtungszusammensetzungen aus Polyvinylidenfluorid,die Polymethylmethacrylat enthalten
US6110188A (en) 1998-03-09 2000-08-29 Corvascular, Inc. Anastomosis method
US20020099438A1 (en) 1998-04-15 2002-07-25 Furst Joseph G. Irradiated stent coating
US20010029351A1 (en) 1998-04-16 2001-10-11 Robert Falotico Drug combinations and delivery devices for the prevention and treatment of vascular disease
US8029561B1 (en) 2000-05-12 2011-10-04 Cordis Corporation Drug combination useful for prevention of restenosis
US7658727B1 (en) 1998-04-20 2010-02-09 Medtronic, Inc Implantable medical device with enhanced biocompatibility and biostability
US20020188037A1 (en) 1999-04-15 2002-12-12 Chudzik Stephen J. Method and system for providing bioactive agent release coating
WO1999055396A1 (en) 1998-04-27 1999-11-04 Surmodics, Inc. Bioactive agent release coating
US6113629A (en) 1998-05-01 2000-09-05 Micrus Corporation Hydrogel for the therapeutic treatment of aneurysms
DE69935716T2 (de) * 1998-05-05 2007-08-16 Boston Scientific Ltd., St. Michael Stent mit glatten enden
US6153252A (en) 1998-06-30 2000-11-28 Ethicon, Inc. Process for coating stents
NL1009551C2 (nl) 1998-07-03 2000-01-07 Cordis Europ Vena cava filter met verbeteringen voor beheerste ejectie.
WO2000002599A1 (en) 1998-07-08 2000-01-20 Advanced Biocompatible Coatings Inc. Biocompatible metallic stents with hydroxy methacrylate coating
US5921933A (en) 1998-08-17 1999-07-13 Medtronic, Inc. Medical devices with echogenic coatings
JP4898991B2 (ja) 1998-08-20 2012-03-21 クック メディカル テクノロジーズ エルエルシー 被覆付植込式医療装置
US6335029B1 (en) 1998-08-28 2002-01-01 Scimed Life Systems, Inc. Polymeric coatings for controlled delivery of active agents
EP1119379A1 (de) 1998-09-02 2001-08-01 Boston Scientific Limited Arzneimittelabgabevorrichtung für stents
WO2000027455A1 (en) 1998-11-06 2000-05-18 Salter Labs Nebulizer mouthpiece and accessories
US6187024B1 (en) 1998-11-10 2001-02-13 Target Therapeutics, Inc. Bioactive coating for vaso-occlusive devices
FR2785812B1 (fr) 1998-11-16 2002-11-29 Commissariat Energie Atomique Protheses bioactives, notamment a proprietes immunosuppressives, antistenose et antithrombose, et leur fabrication
WO2000041738A1 (en) 1999-01-12 2000-07-20 Quanam Medical Corporation Polymer compositions for intraluminal stent
US6090134A (en) 1999-02-16 2000-07-18 Polymerex Medical Corp. Surface fluorinated stent and methods thereof
DE60005423T2 (de) 1999-03-03 2004-07-22 KURARAY CO., LTD, Kurashiki Unterfütterungsmaterial für Zahnprothesen
AU4975500A (en) 1999-04-23 2000-11-10 Agion Technologies, Llc Stent having antimicrobial agent
FR2795326B1 (fr) 1999-06-28 2001-08-31 Adir Composition pharmaceutique solide thermoformable a liberation controlee
US7601270B1 (en) 1999-06-28 2009-10-13 California Institute Of Technology Microfabricated elastomeric valve and pump systems
US6258121B1 (en) 1999-07-02 2001-07-10 Scimed Life Systems, Inc. Stent coating
US6503556B2 (en) 2000-12-28 2003-01-07 Advanced Cardiovascular Systems, Inc. Methods of forming a coating for a prosthesis
US6790228B2 (en) 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US6203551B1 (en) 1999-10-04 2001-03-20 Advanced Cardiovascular Systems, Inc. Chamber for applying therapeutic substances to an implant device
US6638259B1 (en) 1999-10-28 2003-10-28 Scimed Life Systems, Inc. Biocompatible medical devices
US6610087B1 (en) * 1999-11-16 2003-08-26 Scimed Life Systems, Inc. Endoluminal stent having a matched stiffness region and/or a stiffness gradient and methods for providing stent kink resistance
US6355058B1 (en) 1999-12-30 2002-03-12 Advanced Cardiovascular Systems, Inc. Stent with radiopaque coating consisting of particles in a binder
JP4789302B2 (ja) * 2000-04-19 2011-10-12 ホーユー株式会社 染毛剤収納容器
US6776796B2 (en) 2000-05-12 2004-08-17 Cordis Corportation Antiinflammatory drug and delivery device
US6627246B2 (en) 2000-05-16 2003-09-30 Ortho-Mcneil Pharmaceutical, Inc. Process for coating stents and other medical devices using super-critical carbon dioxide
AU2002220950A1 (en) 2000-09-22 2002-04-02 Itzhak Binderman Method for immobilizing poly(hema) on stents
US6716444B1 (en) 2000-09-28 2004-04-06 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
US6254632B1 (en) 2000-09-28 2001-07-03 Advanced Cardiovascular Systems, Inc. Implantable medical device having protruding surface structures for drug delivery and cover attachment
US6863685B2 (en) 2001-03-29 2005-03-08 Cordis Corporation Radiopacity intraluminal medical device
US20020111590A1 (en) 2000-09-29 2002-08-15 Davila Luis A. Medical devices, drug coatings and methods for maintaining the drug coatings thereon
AU1129902A (en) 2000-09-29 2002-04-08 Cordis Corp Coated medical devices
CA2424029C (en) 2000-09-29 2008-01-29 Cordis Corporation Coated medical devices
US6746773B2 (en) 2000-09-29 2004-06-08 Ethicon, Inc. Coatings for medical devices
US7261735B2 (en) 2001-05-07 2007-08-28 Cordis Corporation Local drug delivery devices and methods for maintaining the drug coatings thereon
US20020051730A1 (en) 2000-09-29 2002-05-02 Stanko Bodnar Coated medical devices and sterilization thereof
US6783793B1 (en) 2000-10-26 2004-08-31 Advanced Cardiovascular Systems, Inc. Selective coating of medical devices
CA2430554A1 (en) 2000-12-01 2002-07-25 Nephros Therapeutics, Inc. Intravascular blood conditioning device and use thereof
US6545097B2 (en) 2000-12-12 2003-04-08 Scimed Life Systems, Inc. Drug delivery compositions and medical devices containing block copolymer
KR20030074660A (ko) 2000-12-14 2003-09-19 오스테오테크, 인코포레이티드 탈광물화된 골 입자들을 만드는 방법
US6824559B2 (en) * 2000-12-22 2004-11-30 Advanced Cardiovascular Systems, Inc. Ethylene-carboxyl copolymers as drug delivery matrices
US6663662B2 (en) 2000-12-28 2003-12-16 Advanced Cardiovascular Systems, Inc. Diffusion barrier layer for implantable devices
NZ528994A (en) 2001-04-26 2006-02-24 Control Delivery Sys Inc Sustained release drug delivery system containing codrugs
US6585755B2 (en) 2001-06-29 2003-07-01 Advanced Cardiovascular Polymeric stent suitable for imaging by MRI and fluoroscopy
US7195640B2 (en) 2001-09-25 2007-03-27 Cordis Corporation Coated medical devices for the treatment of vulnerable plaque
US20030065377A1 (en) 2001-09-28 2003-04-03 Davila Luis A. Coated medical devices
US20030073961A1 (en) 2001-09-28 2003-04-17 Happ Dorrie M. Medical device containing light-protected therapeutic agent and a method for fabricating thereof
US7108701B2 (en) 2001-09-28 2006-09-19 Ethicon, Inc. Drug releasing anastomosis devices and methods for treating anastomotic sites
US20030077312A1 (en) 2001-10-22 2003-04-24 Ascher Schmulewicz Coated intraluminal stents and reduction of restenosis using same
US7005137B1 (en) * 2002-06-21 2006-02-28 Advanceed Cardiovascular Systems, Inc. Coating for implantable medical devices
US7217426B1 (en) * 2002-06-21 2007-05-15 Advanced Cardiovascular Systems, Inc. Coatings containing polycationic peptides for cardiovascular therapy
US20040063805A1 (en) 2002-09-19 2004-04-01 Pacetti Stephen D. Coatings for implantable medical devices and methods for fabrication thereof

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EP1517713B1 (de) 2009-11-18
DE60330144D1 (de) 2009-12-31
US7396539B1 (en) 2008-07-08
AU2003245282A1 (en) 2004-01-06
US20090005861A1 (en) 2009-01-01

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