ATE449098T1 - Stereoselektive synthese bestimmter trifluormethylsubstituierter alkohole - Google Patents

Stereoselektive synthese bestimmter trifluormethylsubstituierter alkohole

Info

Publication number
ATE449098T1
ATE449098T1 AT06803728T AT06803728T ATE449098T1 AT E449098 T1 ATE449098 T1 AT E449098T1 AT 06803728 T AT06803728 T AT 06803728T AT 06803728 T AT06803728 T AT 06803728T AT E449098 T1 ATE449098 T1 AT E449098T1
Authority
AT
Austria
Prior art keywords
stereoselective synthesis
substituted alcohols
sup
trifluoromethyl
certain trifluoromethyl
Prior art date
Application number
AT06803728T
Other languages
English (en)
Inventor
Jinhua Song
Jonathan Reeves
Frank Roschangar
Zhulin Tan
Nathan Yee
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Application granted granted Critical
Publication of ATE449098T1 publication Critical patent/ATE449098T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT06803728T 2005-09-30 2006-09-18 Stereoselektive synthese bestimmter trifluormethylsubstituierter alkohole ATE449098T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72214505P 2005-09-30 2005-09-30
PCT/US2006/036157 WO2007040959A1 (en) 2005-09-30 2006-09-18 Stereoselective synthesis of certain trifluoromethyl-substituted alcohols

Publications (1)

Publication Number Publication Date
ATE449098T1 true ATE449098T1 (de) 2009-12-15

Family

ID=37603181

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06803728T ATE449098T1 (de) 2005-09-30 2006-09-18 Stereoselektive synthese bestimmter trifluormethylsubstituierter alkohole

Country Status (8)

Country Link
US (1) US7425629B2 (de)
EP (1) EP1934218B1 (de)
JP (1) JP2009510063A (de)
AT (1) ATE449098T1 (de)
CA (1) CA2623004A1 (de)
DE (1) DE602006010584D1 (de)
ES (1) ES2333820T3 (de)
WO (1) WO2007040959A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20040887A2 (en) * 2002-03-26 2005-04-30 Boehringer Ingelheim Pharmaceuticals Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
EP1539141B1 (de) * 2002-08-29 2010-07-14 Boehringer Ingelheim Pharmaceuticals Inc. 3-(sulfonamidoethyl)-indol-derivate zur verwendung als glucocorticoid-mimetika bei der behandlung von entzündlichen, allergischen und proliferativen erkrankungen
UY28526A1 (es) 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
US7795272B2 (en) 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
EP1836166B1 (de) 2004-12-27 2009-06-17 Boehringer Ingelheim Pharmaceuticals Inc. Glucocorticoid-mimetika, verfahren zu deren herstellung, pharmazeutische zusammensetzungen und deren verwendung
WO2008070507A2 (en) 2006-12-06 2008-06-12 Boehringer Ingelheim International Gmbh Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US20110275808A1 (en) * 2008-04-30 2011-11-10 Boehringer Ingelheim International Gmbh Stereoselective synthesis of certain trifluoromethyl-substituted alcohols
SI2300472T1 (sl) 2008-06-06 2012-05-31 Boehringer Ingelheim Int Glukokortikoidni mimetiki postopki za njihovo pripravo farmacevtski sestavki in njihove uporabe
US20100312013A1 (en) * 2009-06-03 2010-12-09 Boehringer Ingelheim International Gmbh Steroselective synthesis of certain trifluoromethyl-substituted alcohols
US20110130567A1 (en) * 2009-06-03 2011-06-02 Boehringer Ingelheim International Gmbh Steroselective synthesis of certain trifluoromethyl-substituted alcohols
WO2016057931A1 (en) 2014-10-10 2016-04-14 The Research Foundation For The State University Of New York Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69906849T2 (de) * 1998-02-16 2004-01-22 Ajinomoto Co., Inc. Verfahren zur Herstellung von optisch aktiven Phenylpropionsäure-Derivat
HRP20040887A2 (en) * 2002-03-26 2005-04-30 Boehringer Ingelheim Pharmaceuticals Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
UY28526A1 (es) * 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
US7179919B2 (en) * 2004-03-18 2007-02-20 Boehringer Ingelheim Pharmaceuticals, Inc. Stereoselective synthesis of certain trifluoromethyl-substituted alcohols

Also Published As

Publication number Publication date
ES2333820T3 (es) 2010-03-01
EP1934218A1 (de) 2008-06-25
US20070100142A1 (en) 2007-05-03
JP2009510063A (ja) 2009-03-12
DE602006010584D1 (de) 2009-12-31
US7425629B2 (en) 2008-09-16
WO2007040959A1 (en) 2007-04-12
EP1934218B1 (de) 2009-11-18
CA2623004A1 (en) 2007-04-12

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