ATE445611T1 - Regiospezifische synthese von nikotinderivaten - Google Patents
Regiospezifische synthese von nikotinderivatenInfo
- Publication number
- ATE445611T1 ATE445611T1 AT03790030T AT03790030T ATE445611T1 AT E445611 T1 ATE445611 T1 AT E445611T1 AT 03790030 T AT03790030 T AT 03790030T AT 03790030 T AT03790030 T AT 03790030T AT E445611 T1 ATE445611 T1 AT E445611T1
- Authority
- AT
- Austria
- Prior art keywords
- nicotine derivatives
- regiospecific synthesis
- synthesis
- derivatives
- methods
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical class CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
- C07F7/0814—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring is substituted at a C ring atom by Si
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/0825—Preparations of compounds not comprising Si-Si or Si-cyano linkages
- C07F7/083—Syntheses without formation of a Si-C bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2003/037655 WO2005058920A1 (en) | 2003-11-17 | 2003-11-17 | Regiospecific synthesis of nicotine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE445611T1 true ATE445611T1 (de) | 2009-10-15 |
Family
ID=34699475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03790030T ATE445611T1 (de) | 2003-11-17 | 2003-11-17 | Regiospezifische synthese von nikotinderivaten |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1685138B1 (de) |
| JP (1) | JP2007521245A (de) |
| AT (1) | ATE445611T1 (de) |
| AU (1) | AU2003293039C1 (de) |
| CA (1) | CA2546260A1 (de) |
| DE (1) | DE60329721D1 (de) |
| WO (1) | WO2005058920A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007126826A2 (en) * | 2006-03-29 | 2007-11-08 | North Carolina State University | Synthesis and regioselective substitution of 6-halo- and 6-alkoxy nicotine derivatives |
| CN113149958A (zh) * | 2014-10-22 | 2021-07-23 | 下一代实验室有限责任公司 | (r,s)-烟碱的制备方法 |
| TW202317528A (zh) * | 2021-06-24 | 2023-05-01 | 美商富曼西公司 | 用於防治無脊椎有害生物的唑類化合物 |
| CN113999201B (zh) * | 2021-11-03 | 2023-11-03 | 成昌梅 | 一种烟碱的合成制备方法 |
| CN118834163B (zh) * | 2024-06-26 | 2025-09-16 | 安徽大学 | 一种4-(叔丁基)-2-氯吡啶的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4855433A (en) * | 1988-03-29 | 1989-08-08 | Indiana University Foundation | Silanes |
| US5164504A (en) * | 1991-01-16 | 1992-11-17 | Abbott Laboratories | Haptens, tracers, immunogens and antibodies for immunoassays for cotinine derivatives |
| US5703100A (en) * | 1994-11-10 | 1997-12-30 | Sibia Neurosciences, Inc. | Modulators of acetylcholine receptors |
| US5876727A (en) * | 1995-03-31 | 1999-03-02 | Immulogic Pharmaceutical Corporation | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same |
-
2003
- 2003-11-17 WO PCT/US2003/037655 patent/WO2005058920A1/en not_active Ceased
- 2003-11-17 DE DE60329721T patent/DE60329721D1/de not_active Expired - Lifetime
- 2003-11-17 AT AT03790030T patent/ATE445611T1/de not_active IP Right Cessation
- 2003-11-17 EP EP03790030A patent/EP1685138B1/de not_active Expired - Lifetime
- 2003-11-17 CA CA002546260A patent/CA2546260A1/en not_active Abandoned
- 2003-11-17 AU AU2003293039A patent/AU2003293039C1/en not_active Ceased
- 2003-11-17 JP JP2005512246A patent/JP2007521245A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1685138B1 (de) | 2009-10-14 |
| DE60329721D1 (de) | 2009-11-26 |
| EP1685138A1 (de) | 2006-08-02 |
| EP1685138A4 (de) | 2008-08-13 |
| JP2007521245A (ja) | 2007-08-02 |
| AU2003293039C1 (en) | 2010-08-12 |
| AU2003293039A1 (en) | 2005-07-05 |
| WO2005058920A1 (en) | 2005-06-30 |
| AU2003293039B2 (en) | 2010-04-08 |
| CA2546260A1 (en) | 2005-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |