ATE449162T1 - Herstellung von tcr gamma delta t-zellen - Google Patents
Herstellung von tcr gamma delta t-zellenInfo
- Publication number
- ATE449162T1 ATE449162T1 AT01921047T AT01921047T ATE449162T1 AT E449162 T1 ATE449162 T1 AT E449162T1 AT 01921047 T AT01921047 T AT 01921047T AT 01921047 T AT01921047 T AT 01921047T AT E449162 T1 ATE449162 T1 AT E449162T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- gamma delta
- tcr gamma
- production
- growth factors
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 5
- 102000011778 gamma-delta T-Cell Antigen Receptors Human genes 0.000 title abstract 4
- 108010062214 gamma-delta T-Cell Antigen Receptors Proteins 0.000 title abstract 4
- 239000003102 growth factor Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 2
- 238000012258 culturing Methods 0.000 abstract 2
- 239000001963 growth medium Substances 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 1
- 239000003226 mitogen Substances 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/515—CD3, T-cell receptor complex
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19403300P | 2000-04-03 | 2000-04-03 | |
| PCT/CA2001/000444 WO2001075072A2 (en) | 2000-04-03 | 2001-04-03 | PRODUCTION OF TcR GAMMA DELTA T CELLS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE449162T1 true ATE449162T1 (de) | 2009-12-15 |
Family
ID=22716029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01921047T ATE449162T1 (de) | 2000-04-03 | 2001-04-03 | Herstellung von tcr gamma delta t-zellen |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1268746B1 (de) |
| JP (1) | JP4982645B2 (de) |
| AT (1) | ATE449162T1 (de) |
| AU (2) | AU4816201A (de) |
| CA (1) | CA2405050C (de) |
| DE (1) | DE60140526D1 (de) |
| ES (1) | ES2336302T3 (de) |
| NZ (1) | NZ522337A (de) |
| WO (1) | WO2001075072A2 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9018004B2 (en) | 2005-11-18 | 2015-04-28 | University Health Network | Method of expanding double negative T cells |
| EP2053123B1 (de) | 2006-08-01 | 2014-01-15 | NAI Inc. | Verfahren zur proliferation einer lak-zelle |
| GB201506423D0 (en) | 2015-04-15 | 2015-05-27 | Tc Biopharm Ltd | Gamma delta T cells and uses thereof |
| BR112017000464A2 (pt) * | 2014-07-09 | 2017-11-07 | Tc Biopharm Ltd | células gama delta t e uso das mesmas |
| GB201507368D0 (en) | 2015-04-30 | 2015-06-17 | Ucl Business Plc | Cell |
| DK3307875T3 (da) | 2015-06-09 | 2022-03-21 | Lymphact Lymphocyte Activation Tech S A | Fremgangsmåder til fremstilling af tcr-gamma-delta+-t-celler |
| US11166983B2 (en) * | 2015-06-09 | 2021-11-09 | Lymphact—Lymphocyte Activation Technologies, S.A. | Methods for the production of TCRγδ+ T cells |
| JP6621171B2 (ja) * | 2015-06-22 | 2019-12-18 | 国立大学法人広島大学 | T細胞活性化剤、t細胞の活性化方法、および、t細胞培養用培地 |
| US12391739B2 (en) | 2018-07-13 | 2025-08-19 | Kyoto University | Method for producing gamma delta T cells |
| MX2022006288A (es) | 2019-11-25 | 2022-06-08 | Univ Kyoto | Banco de celulas maestras de celulas t. |
| CA3235971A1 (en) * | 2021-10-20 | 2023-04-27 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Methods and materials for expanding tumor infiltrating gamma-delta t cells |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002515756A (ja) * | 1997-01-31 | 2002-05-28 | ヘモソル インク. | 選択されたリンパ球の生産方法 |
| JPH10295368A (ja) * | 1997-04-22 | 1998-11-10 | Hitachi Chem Co Ltd | ガンマー・デルタt細胞の製造法及び免疫治療剤 |
| WO1999046365A1 (en) * | 1998-03-12 | 1999-09-16 | Emory University | Methods and compositions for the selective expansion of gamma/delta t-cells |
| DE69940352D1 (de) * | 1998-11-04 | 2009-03-12 | Therapure Biopharma Inc | Verfahren zur herstellung von gamma delta t zellen |
-
2001
- 2001-04-03 JP JP2001572946A patent/JP4982645B2/ja not_active Expired - Fee Related
- 2001-04-03 CA CA2405050A patent/CA2405050C/en not_active Expired - Fee Related
- 2001-04-03 AU AU4816201A patent/AU4816201A/xx active Pending
- 2001-04-03 NZ NZ522337A patent/NZ522337A/xx unknown
- 2001-04-03 AU AU2001248162A patent/AU2001248162B2/en not_active Ceased
- 2001-04-03 EP EP01921047A patent/EP1268746B1/de not_active Expired - Lifetime
- 2001-04-03 WO PCT/CA2001/000444 patent/WO2001075072A2/en not_active Ceased
- 2001-04-03 DE DE60140526T patent/DE60140526D1/de not_active Expired - Lifetime
- 2001-04-03 ES ES01921047T patent/ES2336302T3/es not_active Expired - Lifetime
- 2001-04-03 AT AT01921047T patent/ATE449162T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU4816201A (en) | 2001-10-15 |
| JP4982645B2 (ja) | 2012-07-25 |
| ES2336302T3 (es) | 2010-04-12 |
| DE60140526D1 (de) | 2009-12-31 |
| EP1268746A2 (de) | 2003-01-02 |
| NZ522337A (en) | 2004-12-24 |
| AU2001248162B2 (en) | 2007-02-01 |
| CA2405050A1 (en) | 2001-10-11 |
| WO2001075072A2 (en) | 2001-10-11 |
| WO2001075072A3 (en) | 2002-04-25 |
| EP1268746B1 (de) | 2009-11-18 |
| JP2003529363A (ja) | 2003-10-07 |
| CA2405050C (en) | 2010-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |