ATE449615T1 - Bilderzeugung mittels magnetischer kernresonanz unter einwirkung hyperpolarisierter edelgase - Google Patents

Bilderzeugung mittels magnetischer kernresonanz unter einwirkung hyperpolarisierter edelgase

Info

Publication number
ATE449615T1
ATE449615T1 AT95916198T AT95916198T ATE449615T1 AT E449615 T1 ATE449615 T1 AT E449615T1 AT 95916198 T AT95916198 T AT 95916198T AT 95916198 T AT95916198 T AT 95916198T AT E449615 T1 ATE449615 T1 AT E449615T1
Authority
AT
Austria
Prior art keywords
noble gas
spatial distribution
imaging
hyperpolarized
xenon
Prior art date
Application number
AT95916198T
Other languages
English (en)
Inventor
Dilip Balamore
Gordon Cates
Bastiaan Driehuys
William Happer
Brian Saam
Arnold Wishnia
Mitchell Albert
Original Assignee
Univ New York State Res Found
Univ Princeton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found, Univ Princeton filed Critical Univ New York State Res Found
Application granted granted Critical
Publication of ATE449615T1 publication Critical patent/ATE449615T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/282—Means specially adapted for hyperpolarisation or for hyperpolarised contrast agents, e.g. for the generation of hyperpolarised gases using optical pumping cells, for storing hyperpolarised contrast agents or for the determination of the polarisation of a hyperpolarised contrast agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Signal Processing (AREA)
  • Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Magnetic Variables (AREA)
AT95916198T 1994-04-08 1995-04-04 Bilderzeugung mittels magnetischer kernresonanz unter einwirkung hyperpolarisierter edelgase ATE449615T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/225,243 US5545396A (en) 1994-04-08 1994-04-08 Magnetic resonance imaging using hyperpolarized noble gases
PCT/US1995/004175 WO1995027438A1 (en) 1994-04-08 1995-04-04 Magnetic resonance imaging using hyperpolarized noble gases

Publications (1)

Publication Number Publication Date
ATE449615T1 true ATE449615T1 (de) 2009-12-15

Family

ID=22844121

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95916198T ATE449615T1 (de) 1994-04-08 1995-04-04 Bilderzeugung mittels magnetischer kernresonanz unter einwirkung hyperpolarisierter edelgase

Country Status (8)

Country Link
US (5) US5545396A (de)
EP (2) EP0754009B1 (de)
JP (1) JP3645569B2 (de)
AT (1) ATE449615T1 (de)
AU (1) AU709515B2 (de)
CA (1) CA2183740C (de)
DE (1) DE69536022D1 (de)
WO (1) WO1995027438A1 (de)

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US6593144B2 (en) 2003-07-15
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US5785953A (en) 1998-07-28
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AU709515B2 (en) 1999-09-02
US20010000726A1 (en) 2001-05-03
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US5545396A (en) 1996-08-13
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US5789921A (en) 1998-08-04
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