ATE449775T1 - Carbacephem beta-lactam-antibiotika - Google Patents

Carbacephem beta-lactam-antibiotika

Info

Publication number
ATE449775T1
ATE449775T1 AT04750798T AT04750798T ATE449775T1 AT E449775 T1 ATE449775 T1 AT E449775T1 AT 04750798 T AT04750798 T AT 04750798T AT 04750798 T AT04750798 T AT 04750798T AT E449775 T1 ATE449775 T1 AT E449775T1
Authority
AT
Austria
Prior art keywords
carbacephem
beta
lactam antibiotics
antibiotics
methicillin
Prior art date
Application number
AT04750798T
Other languages
English (en)
Inventor
Tomasz Glinka
Scott Hecker
Original Assignee
Trine Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trine Pharmaceuticals Inc filed Critical Trine Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE449775T1 publication Critical patent/ATE449775T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
AT04750798T 2003-04-30 2004-04-27 Carbacephem beta-lactam-antibiotika ATE449775T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46698203P 2003-04-30 2003-04-30
PCT/US2004/013054 WO2004098500A2 (en) 2003-04-30 2004-04-27 CARBACEPHEM ss-LACTAM ANTIBIOTICS

Publications (1)

Publication Number Publication Date
ATE449775T1 true ATE449775T1 (de) 2009-12-15

Family

ID=33435002

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04750798T ATE449775T1 (de) 2003-04-30 2004-04-27 Carbacephem beta-lactam-antibiotika

Country Status (10)

Country Link
US (1) US7109190B2 (de)
EP (2) EP2161268A1 (de)
JP (1) JP2006525340A (de)
AT (1) ATE449775T1 (de)
CA (1) CA2526875A1 (de)
DE (1) DE602004024297D1 (de)
DK (1) DK1618106T3 (de)
ES (1) ES2336917T3 (de)
MX (1) MXPA05011681A (de)
WO (1) WO2004098500A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090123367A1 (en) * 2003-03-05 2009-05-14 Delfmems Soluble Glycosaminoglycanases and Methods of Preparing and Using Soluble Glycosaminoglycanases
US7767429B2 (en) * 2003-03-05 2010-08-03 Halozyme, Inc. Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
US7871607B2 (en) 2003-03-05 2011-01-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
US20060104968A1 (en) 2003-03-05 2006-05-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
US20080146535A1 (en) * 2003-04-30 2008-06-19 Tomasz Glinka Compositions comprising carbacephem beta-lactam antibiotics and beta-lactamase inhibitors
US8263613B2 (en) * 2007-02-16 2012-09-11 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab I inhibitors
KR20100093532A (ko) * 2007-10-25 2010-08-25 아카오젠, 인코포레이티드 카바세펨 β―락탐 항생제
WO2010030810A1 (en) * 2008-09-10 2010-03-18 Achaogen, Inc. Carbacephem beta-lactam antibiotics
WO2010030811A2 (en) * 2008-09-10 2010-03-18 Achaogen, Inc. CARBACEPHEM β-LACTAM ANTIBIOTICS
WO2010123997A1 (en) * 2009-04-22 2010-10-28 Achaogen, Inc. Carbacephem beta-lactam antibiotics
KR102869384B1 (ko) 2017-07-07 2025-10-15 에피센트알엑스, 인코포레이티드 치료제의 비경구 투여를 위한 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60174787A (ja) * 1984-02-21 1985-09-09 Kyowa Hakko Kogyo Co Ltd 3位置換カルバセフエム化合物
NO165842C (no) * 1984-04-23 1991-04-17 Takeda Chemical Industries Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-forbindelser.
US4788185A (en) * 1984-04-23 1988-11-29 Takeda Chemical Industries, Ltd. Cephalosporin compounds
JPH0830070B2 (ja) * 1985-09-27 1996-03-27 武田薬品工業株式会社 抗菌性化合物
US4826834A (en) * 1985-09-27 1989-05-02 Takeda Chemical Industries, Ltd. Cephem compounds
US5077287A (en) * 1991-01-18 1991-12-31 Eli Lilly And Company 3-thiazolylthio carbacephem antibacterial agents
US5565445A (en) * 1995-02-22 1996-10-15 Merck & Co., Inc. 3-thioheteroaryl 1-carba-1-dethiacephalosporin compounds, compositions and methods of use
AR029004A1 (es) * 1999-09-22 2003-06-04 Essential Therapeutics Inc Compuesto del acido 7-acilamino-3-heteroariltio-3-cefem carboxilico y su uso para la preparacion de una composicion antibacteriana
US6599893B2 (en) * 2000-08-29 2003-07-29 Essential Therapeutics, Inc. Cephalosporin antibiotics and prodrugs thereof

Also Published As

Publication number Publication date
EP1618106A4 (de) 2006-11-22
EP1618106A2 (de) 2006-01-25
US20050004095A1 (en) 2005-01-06
DE602004024297D1 (de) 2010-01-07
US7109190B2 (en) 2006-09-19
EP1618106B1 (de) 2009-11-25
CA2526875A1 (en) 2004-11-18
DK1618106T3 (da) 2010-03-15
MXPA05011681A (es) 2006-06-27
ES2336917T3 (es) 2010-04-19
WO2004098500A2 (en) 2004-11-18
WO2004098500A3 (en) 2005-06-02
JP2006525340A (ja) 2006-11-09
EP2161268A1 (de) 2010-03-10

Similar Documents

Publication Publication Date Title
HUP0400446A2 (hu) Azitromicin kristályformái
TW200507841A (en) Antibacterial agents
MXPA05009352A (es) Metodos y composiciones para tratamiento y prevencion de staphylococcus y otras infecciones bacterianas.
MX2010004407A (es) Antibioticos de carbacefem beta-lactama.
ATE344799T1 (de) Piperidinderivate als antibakterielle mittel
BRPI0414694A (pt) pró-fármaco(s) aciloximetilcarbamato de oxazolidinonas
DE60307860D1 (de) Aminocyclohexenchinoline und ihre azaisosterischen analoga mit antibakterieller wirkung
DE50306587D1 (de) Antibakterielle amid-makrozyklen
ATE388153T1 (de) Quervernetzte glycopeptid-cephalosporin- antibiotika
IL189017A0 (en) 8-methoxy-9h-isothiazolo[5,4-b]quinoline-3,4-diones and related compounds as anti-effective agents
DK1618106T3 (da) Carbacephem beta-lactam antibiotika
ATE450540T1 (de) Quervernetzte glycopeptid-cephalosporin- antibiotika
NO20055893L (no) Nye linkomycinderivativer med antimikrobiell aktivitet
ATE556088T1 (de) Konjugat beinhaltend cephalosporin und glykopeptidantibiotikum
DE60208404D1 (de) Kreuzverquerte glycopeptid-cephalosporin-antibiotika
UY28542A1 (es) Amidas macrocíclicas antibacterianas
WO2010030811A3 (en) CARBACEPHEM β-LACTAM ANTIBIOTICS
EP2495245A3 (de) Grampositive Carbapenem-Antibakterien und Verfahren zu deren Herstellung
CY1107038T1 (el) Μεθοδος θεραπειας βακτηριακων λοιμωξεων με χρηση της γεμιφλοξασινης ή ενος αλατος αυτης και ενος αντιβιοτικου β-λακταμης
DE60207884D1 (de) Monobactam-antibakterielle verbindungen und anwendungsverfahren
MY136854A (en) Crystalline n-formyl hydroxylamine compounds
ATE425984T1 (de) Trizyklische antibakterielle makrolidderivate
DE60115851D1 (de) Anti-infektionsmittel, die gegen gegenüber mehreren arzneimitteln resistente bakterienstämme nützlich sind
WO2003068790A3 (en) Macrolide antibacterial compounds

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties