ATE452911T1 - Virensicherer faktor viii mit niedrigem gehalt an höheren multimeren - Google Patents

Virensicherer faktor viii mit niedrigem gehalt an höheren multimeren

Info

Publication number
ATE452911T1
ATE452911T1 AT04805296T AT04805296T ATE452911T1 AT E452911 T1 ATE452911 T1 AT E452911T1 AT 04805296 T AT04805296 T AT 04805296T AT 04805296 T AT04805296 T AT 04805296T AT E452911 T1 ATE452911 T1 AT E452911T1
Authority
AT
Austria
Prior art keywords
factor viii
higher multimers
filtration
vwf
low content
Prior art date
Application number
AT04805296T
Other languages
English (en)
Inventor
Abdessatar Chtourou
Michel Nogre
Roland Schmitthaeusler
Original Assignee
Lab Francais Du Fractionnement
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34400721&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE452911(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lab Francais Du Fractionnement filed Critical Lab Francais Du Fractionnement
Application granted granted Critical
Publication of ATE452911T1 publication Critical patent/ATE452911T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/022—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
AT04805296T 2003-10-23 2004-10-25 Virensicherer faktor viii mit niedrigem gehalt an höheren multimeren ATE452911T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0312398A FR2861395B1 (fr) 2003-10-23 2003-10-23 Facteur viii viralement securise a faible teneur en multimeres superieurs
PCT/FR2004/002737 WO2005040214A1 (fr) 2003-10-23 2004-10-25 Facteur viii viralement securise a faible teneur en multimeres superieurs

Publications (1)

Publication Number Publication Date
ATE452911T1 true ATE452911T1 (de) 2010-01-15

Family

ID=34400721

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04805296T ATE452911T1 (de) 2003-10-23 2004-10-25 Virensicherer faktor viii mit niedrigem gehalt an höheren multimeren

Country Status (12)

Country Link
US (1) US7932355B2 (de)
EP (3) EP1675872B1 (de)
JP (2) JP4872669B2 (de)
AT (1) ATE452911T1 (de)
AU (1) AU2004283931B2 (de)
BR (1) BRPI0415743A (de)
CA (1) CA2543095C (de)
DE (1) DE602004024812D1 (de)
ES (1) ES2335893T3 (de)
FR (1) FR2861395B1 (de)
IL (3) IL175027A (de)
WO (1) WO2005040214A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2920429B1 (fr) * 2007-08-30 2012-10-05 Lfb Biotechnologies Procede de purification du facteur viii et du facteur von willebrand
DK2242479T3 (da) 2007-12-28 2012-01-02 Baxter Int Modtryksfiltrering af proteiner
US11197916B2 (en) 2007-12-28 2021-12-14 Takeda Pharmaceutical Company Limited Lyophilized recombinant VWF formulations
WO2009086400A2 (en) * 2007-12-28 2009-07-09 Baxter International Inc. Recombinant vwf formulations
ES2298096B1 (es) * 2008-01-08 2009-01-01 Grifols, S.A. Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos.
DK2349314T3 (da) * 2008-10-21 2013-05-27 Baxter Int Lyofiliserede præparater af rekombinant VWF
EP2725033B1 (de) * 2011-06-24 2017-08-09 Asahi Kasei Medical Co., Ltd. Verfahren zur herstellung eines proteinpräparats
WO2013083858A1 (en) 2012-04-24 2013-06-13 Novo Nordisk A/S Compounds suitable for treatment of haemophilia
CN104804078B (zh) * 2015-05-05 2019-01-04 广东卫伦生物制药有限公司 人体血清凝血因子ⅷ中的病毒过滤方法
BR112020002234A2 (pt) 2017-08-23 2020-07-28 Csl Behring Gmbh método para a filtragem de virus do fator von willebrand
JP2021513913A (ja) * 2018-02-19 2021-06-03 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ 修正フィルタ膜及び方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9500724D0 (sv) 1994-06-23 1995-02-24 Pharmacia Ab Filtrering
US5522991A (en) 1994-07-20 1996-06-04 Millipore Investment Holdings Limited Cellulosic ultrafiltration membrane
EP0860444A1 (de) * 1997-02-24 1998-08-26 Stichting Centraal Laboratorium van de Bloedtransfusiedienst van het Nederlandse Rode Kruis (CLB) Methode zur Entfernung von Viren aus Proteinlösungen
FR2772381B1 (fr) * 1997-12-15 2001-06-08 Lab Francais Du Fractionnement Procede de preparation par filtration d'une solution de facteur viii securisee viralement
WO2001064754A1 (en) 2000-03-03 2001-09-07 Kyowa Hakko Kogyo Co., Ltd. Gene recombinant antibody and its fragment
DK2314686T4 (da) 2000-10-06 2023-08-21 Kyowa Kirin Co Ltd Celler, der danner antistofsammensætninger
KR100988949B1 (ko) 2001-10-25 2010-10-20 제넨테크, 인크. 당단백질 조성물
DE10211632A1 (de) 2002-03-15 2003-10-09 Aventis Behring Gmbh Verfahren zur Abtrennung von Viren aus einer Proteinlösung durch Nanofiltration
ES2298096B1 (es) 2008-01-08 2009-01-01 Grifols, S.A. Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos.

Also Published As

Publication number Publication date
ES2335893T3 (es) 2010-04-06
EP2108659A1 (de) 2009-10-14
IL175027A0 (en) 2006-08-20
CA2543095C (fr) 2017-07-11
US20070275880A1 (en) 2007-11-29
FR2861395B1 (fr) 2006-02-17
EP1675872A1 (de) 2006-07-05
FR2861395A1 (fr) 2005-04-29
IL228278A (en) 2015-07-30
BRPI0415743A (pt) 2006-12-19
JP2011252016A (ja) 2011-12-15
JP4872669B2 (ja) 2012-02-08
EP2805968A1 (de) 2014-11-26
EP1675872B1 (de) 2009-12-23
IL175027A (en) 2013-10-31
JP2007535487A (ja) 2007-12-06
DE602004024812D1 (de) 2010-02-04
CA2543095A1 (fr) 2005-05-06
US7932355B2 (en) 2011-04-26
AU2004283931B2 (en) 2010-08-26
AU2004283931A1 (en) 2005-05-06
IL228277A (en) 2015-07-30
WO2005040214A1 (fr) 2005-05-06

Similar Documents

Publication Publication Date Title
IL228278A (en) Anti-coagulation factor viii, derived from plasma, is safe in terms of virus content
Al‐Ammar et al. The use of collagen cross‐linking agents to enhance dentin bond strength
ES2363827T3 (es) Procedimiento para la obtención de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilización de los mismos.
KR930016109A (ko) 안정한 피브리노겐 용액
CA2421681C (en) Method for separating off viruses from a protein solution by means of nanofiltration
DE60133541D1 (de) Modifizierter faktor viii
CN101677836A (zh) 用于制备纤维蛋白胶的含有浓缩纤维蛋白原的组合物和相关系统的制备方法
DE60231977D1 (de) Abtrennung von thrombozyten aus vollblut zur verwendung als wundheilmittel
DE60021098T2 (de) Von isoagglutinin befreite blutzusammensetzungen und verfahren zu ihrer herstellung
MX9704059A (es) Derivado de amidinonaftilo novedoso o sal del mismo.
Aznar et al. Factor VIII/von Willebrand factor complex in methylene blue‐treated fresh plasma
Buchta et al. Fibrin sealant produced by the CryoSeal® FS system: product chemistry, material properties and possible preparation in the autologous preoperative setting
DE69827787D1 (de) Verfahren zur entfernung von viren aus proteinlösungen mittels nanofiltration
BR9708639A (pt) Composição estabilizadora
JP4312381B2 (ja) 濾過によるウイルス的に安全な因子ｖｉｉｉ溶液の調製方法
KR960031474A (ko) 한외여과에 의한 단백질 용액으로부터의 바이러스의 제거방법
ATE431363T1 (de) Modifizierte faktor viii cdna und ihre verwendung zur produktion von faktor viii
ATE421339T1 (de) Vereinfachte methode zur entfernung von freiem protein während der herstellung von protein- polysaccharid-konjugaten und impfstoffen unter verwendung von medien mit limitierter durchlässigkeit
ATE386055T1 (de) Konzentrat eines faktor viii:c-haltigen von- willebrand-faktors und das dazu gehörige verfahren
ATE358507T1 (de) Herstellung von dialysekonzentrat aus einer hochverdichteten konzentratvorstufe und vorrichtung zur anwendung am dialyseplatz.
ATE190492T1 (de) Verwendung von gift aus hautflüglern (hymenopteren) zur herstellung eines medikamentes zur behandlung von infektionen durch dna-viren
Yousef et al. Cryoprecipitate production: the use of additives to enhance the yield
DE602006006352D1 (de) Verfahren zur herstellung des (s)-enantiomers von omeprazol
ATE394109T1 (de) Augentropfen mit gefiltertem lehmhaltigen wasser zur behandlung von glaukom

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties