ATE454039T1 - Verfharen zur herstellung von herpes-simplex- virus-amplikons, die resultierenden amplikons und ihre verwendung - Google Patents

Verfharen zur herstellung von herpes-simplex- virus-amplikons, die resultierenden amplikons und ihre verwendung

Info

Publication number
ATE454039T1
ATE454039T1 AT01939333T AT01939333T ATE454039T1 AT E454039 T1 ATE454039 T1 AT E454039T1 AT 01939333 T AT01939333 T AT 01939333T AT 01939333 T AT01939333 T AT 01939333T AT E454039 T1 ATE454039 T1 AT E454039T1
Authority
AT
Austria
Prior art keywords
hsv
amplicons
amplicon particles
amplicon
herpes simplex
Prior art date
Application number
AT01939333T
Other languages
English (en)
Inventor
Howard Federoff
William Bowers
Original Assignee
Univ Rochester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rochester filed Critical Univ Rochester
Application granted granted Critical
Publication of ATE454039T1 publication Critical patent/ATE454039T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01939333T 2000-05-23 2001-05-23 Verfharen zur herstellung von herpes-simplex- virus-amplikons, die resultierenden amplikons und ihre verwendung ATE454039T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20649700P 2000-05-23 2000-05-23
PCT/US2001/016682 WO2001089304A1 (en) 2000-05-23 2001-05-23 Method of producing herpes simplex virus amplicons, resulting amplicons, and their use

Publications (1)

Publication Number Publication Date
ATE454039T1 true ATE454039T1 (de) 2010-01-15

Family

ID=22766659

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01939333T ATE454039T1 (de) 2000-05-23 2001-05-23 Verfharen zur herstellung von herpes-simplex- virus-amplikons, die resultierenden amplikons und ihre verwendung

Country Status (7)

Country Link
EP (1) EP1289368B1 (de)
AT (1) ATE454039T1 (de)
AU (2) AU6486201A (de)
CA (1) CA2410536A1 (de)
DE (1) DE60141014D1 (de)
DK (1) DK1289368T3 (de)
WO (1) WO2001089304A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2430589A1 (en) 2000-11-29 2002-07-25 University Of Rochester Helper virus-free herpes virus amplicon particles and uses thereof
US8092791B2 (en) 2001-05-23 2012-01-10 University Of Rochester Method of producing herpes simplex virus amplicons, resulting amplicons, and their use
WO2003101396A2 (en) * 2002-05-31 2003-12-11 University Of Rochester Helper virus-free herpesvirus amplicon particles and uses thereof
US7399851B2 (en) 2002-07-25 2008-07-15 Dana Farber Cancer Institute, Inc. Composition and method for imaging cells
US20060239970A1 (en) * 2003-01-23 2006-10-26 Federoff Howard J Herpesvirus amplicon particles
WO2005082415A2 (en) 2004-02-25 2005-09-09 Dana Farber Cancer Institute, Inc. Inhibitors of insulin-like growth factor receptor-1 for inhibiting tumor cell growth
US7968762B2 (en) 2004-07-13 2011-06-28 Van Andel Research Institute Immune-compromised transgenic mice expressing human hepatocyte growth factor (hHGF)
WO2006135602A2 (en) * 2005-06-03 2006-12-21 University Of Rochester Herpes virus-based compositions and methods of use in the prenatal and perinatal periods
WO2007143681A2 (en) * 2006-06-06 2007-12-13 University Of Rochester Helper virus-free herpesvirus amplicon particles and uses thereof
JP2010510772A (ja) 2006-11-27 2010-04-08 パトリス リミテッド 新生細胞における新規なグリコシル化ペプチド標的
EP2185719B1 (de) 2007-08-02 2013-11-13 NovImmune SA Rantes-antikörper und verfahren zu ihrer verwendung
EP2350264A4 (de) 2008-11-06 2012-08-29 Univ Johns Hopkins Behandlung von chronisch-entzündlichen atemwegserkrankungen
EP2258858A1 (de) 2009-06-05 2010-12-08 Universitätsklinikum Freiburg Für LSD1 transgenisches Tiermodell für Krebs
US9163240B2 (en) 2009-12-07 2015-10-20 The Johns Hopkins University SR-BI mutation as a predictor of low progesterone levels and poor fetal viability during pregnancy
WO2017197355A2 (en) 2016-05-13 2017-11-16 4D Molecular Therapeutics Inc. Adeno-associated virus variant capsids and methods of use thereof
DK3684423T5 (da) 2017-09-20 2024-08-26 4D Molecular Therapeutics Inc Adeno-associerede virusvariantcapsider og fremgangsmåder til anvendelse deraf
US11766489B2 (en) 2017-11-27 2023-09-26 4D Molecular Therapeutics, Inc. Adeno-associated virus variant capsids and use for inhibiting angiogenesis
CN115552021A (zh) 2020-04-27 2022-12-30 4D分子治疗有限公司 用于肺递送的腺相关变体、制剂和方法
EP4349852A4 (de) 2021-05-28 2025-09-03 Shanghai Regenelead Therapies Co Ltd Rekombinantes adeno-assoziiertes virus mit veränderlichem kapsid und anwendung davon

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2045129A1 (en) * 1989-02-01 1990-08-02 Alfred I. Geller Herpes simplex virus type i expression vector

Also Published As

Publication number Publication date
EP1289368A4 (de) 2006-04-19
AU2001264862B2 (en) 2006-03-30
DK1289368T3 (da) 2010-05-03
WO2001089304A1 (en) 2001-11-29
AU6486201A (en) 2001-12-03
CA2410536A1 (en) 2001-11-29
EP1289368B1 (de) 2010-01-06
DE60141014D1 (de) 2010-02-25
EP1289368A1 (de) 2003-03-12

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