ATE454039T1 - Verfharen zur herstellung von herpes-simplex- virus-amplikons, die resultierenden amplikons und ihre verwendung - Google Patents

Verfharen zur herstellung von herpes-simplex- virus-amplikons, die resultierenden amplikons und ihre verwendung

Info

Publication number
ATE454039T1
ATE454039T1 AT01939333T AT01939333T ATE454039T1 AT E454039 T1 ATE454039 T1 AT E454039T1 AT 01939333 T AT01939333 T AT 01939333T AT 01939333 T AT01939333 T AT 01939333T AT E454039 T1 ATE454039 T1 AT E454039T1
Authority
AT
Austria
Prior art keywords
hsv
amplicons
amplicon particles
amplicon
herpes simplex
Prior art date
Application number
AT01939333T
Other languages
English (en)
Inventor
Howard Federoff
William Bowers
Original Assignee
Univ Rochester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rochester filed Critical Univ Rochester
Application granted granted Critical
Publication of ATE454039T1 publication Critical patent/ATE454039T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
AT01939333T 2000-05-23 2001-05-23 Verfharen zur herstellung von herpes-simplex- virus-amplikons, die resultierenden amplikons und ihre verwendung ATE454039T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20649700P 2000-05-23 2000-05-23
PCT/US2001/016682 WO2001089304A1 (en) 2000-05-23 2001-05-23 Method of producing herpes simplex virus amplicons, resulting amplicons, and their use

Publications (1)

Publication Number Publication Date
ATE454039T1 true ATE454039T1 (de) 2010-01-15

Family

ID=22766659

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01939333T ATE454039T1 (de) 2000-05-23 2001-05-23 Verfharen zur herstellung von herpes-simplex- virus-amplikons, die resultierenden amplikons und ihre verwendung

Country Status (7)

Country Link
EP (1) EP1289368B1 (de)
AT (1) ATE454039T1 (de)
AU (2) AU2001264862B2 (de)
CA (1) CA2410536A1 (de)
DE (1) DE60141014D1 (de)
DK (1) DK1289368T3 (de)
WO (1) WO2001089304A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1346036T3 (da) 2000-11-29 2010-07-19 Univ Rochester Virusfri virusamplicon hjælpepartikler samt anvendelser deraf
US8092791B2 (en) 2001-05-23 2012-01-10 University Of Rochester Method of producing herpes simplex virus amplicons, resulting amplicons, and their use
AU2003237326A1 (en) * 2002-05-31 2003-12-19 University Of Rochester Helper virus-free herpesvirus amplicon particles and uses thereof
US7399851B2 (en) 2002-07-25 2008-07-15 Dana Farber Cancer Institute, Inc. Composition and method for imaging cells
EP1592455A4 (de) * 2003-01-23 2006-06-28 Univ Rochester Herpesvirus-amplicon-teilchen
WO2005082415A2 (en) 2004-02-25 2005-09-09 Dana Farber Cancer Institute, Inc. Inhibitors of insulin-like growth factor receptor-1 for inhibiting tumor cell growth
US7968762B2 (en) 2004-07-13 2011-06-28 Van Andel Research Institute Immune-compromised transgenic mice expressing human hepatocyte growth factor (hHGF)
US20080226601A1 (en) * 2005-06-03 2008-09-18 University Of Rochester Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods
WO2007143681A2 (en) * 2006-06-06 2007-12-13 University Of Rochester Helper virus-free herpesvirus amplicon particles and uses thereof
EP2101813B1 (de) 2006-11-27 2014-04-02 Patrys Limited Neues glykosyliertes zielpeptid in neoplastischen zellen
ES2453592T3 (es) 2007-08-02 2014-04-08 Novimmune Sa Anticuerpos anti-RANTES y métodos de uso de los mismos
EP2727996A1 (de) 2008-11-06 2014-05-07 The Johns-Hopkins University Behandlung von chronisch-entzündlichen Atemwegserkrankungen mit NP1 Inhibitoren
EP2258858A1 (de) 2009-06-05 2010-12-08 Universitätsklinikum Freiburg Für LSD1 transgenisches Tiermodell für Krebs
WO2011071916A2 (en) 2009-12-07 2011-06-16 The Johns Hopkins University Sr-bi as a predictor of human female infertility and responsiveness to treatment
US11364308B2 (en) 2016-05-13 2022-06-21 4D Molecular Therapeutics Inc. Adeno-associated virus variant capsids and methods of use thereof
RU2770922C2 (ru) 2017-09-20 2022-04-25 4Д Молекьюлар Терапьютикс Инк. Капсиды вариантов аденоассоциированных вирусов и методы их применения
CN111770999A (zh) 2017-11-27 2020-10-13 4D分子治疗有限公司 腺相关病毒变体衣壳和用于抑制血管生成的应用
AU2021265768B2 (en) 2020-04-27 2023-03-30 4D Molecular Therapeutics Inc. Adeno-associated variants, formulations and methods for pulmonary delivery
US20240252679A1 (en) 2021-05-28 2024-08-01 Shanghai Regenelead Therapies Co., Ltd. Recombinant adeno-associated virus having variant capsid, and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04503306A (ja) * 1989-02-01 1992-06-18 ザ・ジェネラル・ホスピタル・コーポレーション 単純ヘルペスウイルス１型発現ベクター

Also Published As

Publication number Publication date
EP1289368A4 (de) 2006-04-19
EP1289368B1 (de) 2010-01-06
AU2001264862B2 (en) 2006-03-30
EP1289368A1 (de) 2003-03-12
AU6486201A (en) 2001-12-03
DK1289368T3 (da) 2010-05-03
WO2001089304A1 (en) 2001-11-29
CA2410536A1 (en) 2001-11-29
DE60141014D1 (de) 2010-02-25

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