ATE454467T1 - Verwendung des slug-gens oder der transkriptions- oder expressionsprodukte davon beim nachweis und/oder bei der behandlung von krebsartigen zellen - Google Patents

Verwendung des slug-gens oder der transkriptions- oder expressionsprodukte davon beim nachweis und/oder bei der behandlung von krebsartigen zellen

Info

Publication number
ATE454467T1
ATE454467T1 AT02710865T AT02710865T ATE454467T1 AT E454467 T1 ATE454467 T1 AT E454467T1 AT 02710865 T AT02710865 T AT 02710865T AT 02710865 T AT02710865 T AT 02710865T AT E454467 T1 ATE454467 T1 AT E454467T1
Authority
AT
Austria
Prior art keywords
transcription
cells
expression products
cancerical
treating
Prior art date
Application number
AT02710865T
Other languages
English (en)
Inventor
Garcia Isidro Sanchez
De Matos Alberto Orfao
Losada Jesus Perez
Original Assignee
Univ De Salamanca O T R I
Consejo Superior Investigacion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ De Salamanca O T R I, Consejo Superior Investigacion filed Critical Univ De Salamanca O T R I
Application granted granted Critical
Publication of ATE454467T1 publication Critical patent/ATE454467T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5751Immunoassay; Biospecific binding assay; Materials therefor for cancer of the skin, e.g. melanoma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57505Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT02710865T 2001-01-23 2002-01-23 Verwendung des slug-gens oder der transkriptions- oder expressionsprodukte davon beim nachweis und/oder bei der behandlung von krebsartigen zellen ATE454467T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200100151A ES2185472B1 (es) 2001-01-23 2001-01-23 Empleo del gen slug, o de sus productos de transcripcion o expresion, en la deteccion y/o tratamiento de celulas cancerosas.
PCT/ES2002/000026 WO2002059361A1 (es) 2001-01-23 2002-01-23 Empleo del gen slug o de sus productos de transcripcion o expresion en la deteccion y/o tratamiento de celulas cancerosas

Publications (1)

Publication Number Publication Date
ATE454467T1 true ATE454467T1 (de) 2010-01-15

Family

ID=8496481

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02710865T ATE454467T1 (de) 2001-01-23 2002-01-23 Verwendung des slug-gens oder der transkriptions- oder expressionsprodukte davon beim nachweis und/oder bei der behandlung von krebsartigen zellen

Country Status (7)

Country Link
US (1) US7776519B2 (de)
EP (1) EP1354962B1 (de)
JP (1) JP2004520045A (de)
AT (1) ATE454467T1 (de)
DE (1) DE60234991D1 (de)
ES (4) ES2185472B1 (de)
WO (1) WO2002059361A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2195751B1 (es) 2001-11-27 2005-04-01 Universidad De Salamanca (Otri) Mamiferos no humanos transgenicos como modelos para patologias humanas con origen en celulas stem.
ES2253028B1 (es) * 2003-05-30 2007-08-01 Universidad De Salamanca "empleo del gen slug, sus productos de transcripcion o expresion, y/o compuestos inhibidores o estimuladores de la expresion de slug para conferir radioresistencia o radioproteccion celular.
ES2301268B1 (es) 2004-10-25 2009-05-01 Centro De Investigacion Biomolecular Aplicada Salamanca, S.L. Empleo del gen slug, o de sus productos de replicacion, transcripcion o expresion, en la identificacion, diagnostico, prevencion o tratamiento de la diseminacion del cancer y/o desarrollo de metastasis.
CA2656548A1 (en) * 2005-06-30 2007-01-11 Whitehead Institute Progenitor cells and uses thereof
US20110302665A1 (en) * 2008-07-02 2011-12-08 Oktay Kirak Non-human mammals with t or b cells having predefined specificity
KR101805181B1 (ko) 2016-09-02 2017-12-07 충북대학교 산학협력단 인산화된 slug 단백질의 유사분열 세포에 대한 신규한 바이오 마커로서의 용도
WO2023126958A1 (en) * 2021-12-30 2023-07-06 Mestastop Solutions Private Limited Method for producing a spontaneous metastasis model
CN116747309B (zh) * 2023-06-20 2025-12-05 中山大学 Slug抑制剂在制备华支睾吸虫细胞外囊泡诱导的胆管癌的治疗药物中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US20060019256A1 (en) * 2003-06-09 2006-01-26 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer

Also Published As

Publication number Publication date
ES2242469B1 (es) 2006-07-16
EP1354962A1 (de) 2003-10-22
WO2002059361A1 (es) 2002-08-01
EP1354962B1 (de) 2010-01-06
ES2339335T3 (es) 2010-05-19
JP2004520045A (ja) 2004-07-08
ES2185472B1 (es) 2004-10-16
ES2241402A1 (es) 2005-10-16
ES2241402B1 (es) 2007-02-16
US7776519B2 (en) 2010-08-17
DE60234991D1 (de) 2010-02-25
ES2242469A1 (es) 2005-11-01
US20060141454A1 (en) 2006-06-29
ES2185472A1 (es) 2003-04-16

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