ATE454475T1 - Gerät zur messung der fähigkeit eines enzyms zur modifizierung der supercoil-topologie von nukleinsäuren sowie modulatoren - Google Patents
Gerät zur messung der fähigkeit eines enzyms zur modifizierung der supercoil-topologie von nukleinsäuren sowie modulatorenInfo
- Publication number
- ATE454475T1 ATE454475T1 AT05803594T AT05803594T ATE454475T1 AT E454475 T1 ATE454475 T1 AT E454475T1 AT 05803594 T AT05803594 T AT 05803594T AT 05803594 T AT05803594 T AT 05803594T AT E454475 T1 ATE454475 T1 AT E454475T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- enzyme
- target nucleic
- topology
- modulators
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 12
- 102000039446 nucleic acids Human genes 0.000 title abstract 12
- 108020004707 nucleic acids Proteins 0.000 title abstract 12
- 102000004190 Enzymes Human genes 0.000 title abstract 4
- 108090000790 Enzymes Proteins 0.000 title abstract 4
- 238000000034 method Methods 0.000 abstract 4
- 239000007787 solid Substances 0.000 abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0424953A GB0424953D0 (en) | 2004-11-11 | 2004-11-11 | Assay |
| PCT/GB2005/004346 WO2006051303A1 (en) | 2004-11-11 | 2005-11-10 | Assay for measuring an enzyme’s capability to modify supercoil topology of nucleic acids and modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE454475T1 true ATE454475T1 (de) | 2010-01-15 |
Family
ID=33523584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05803594T ATE454475T1 (de) | 2004-11-11 | 2005-11-10 | Gerät zur messung der fähigkeit eines enzyms zur modifizierung der supercoil-topologie von nukleinsäuren sowie modulatoren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7838230B2 (de) |
| EP (1) | EP1812592B1 (de) |
| AT (1) | ATE454475T1 (de) |
| AU (1) | AU2005303599A1 (de) |
| CA (1) | CA2586534A1 (de) |
| DE (1) | DE602005018808D1 (de) |
| GB (1) | GB0424953D0 (de) |
| WO (1) | WO2006051303A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009037510A1 (en) * | 2007-09-21 | 2009-03-26 | Astrazeneca Ab | Dna decatenation assay 997 |
| WO2009037511A1 (en) * | 2007-09-21 | 2009-03-26 | Astrazeneca Ab | Assay for dna supercoiling/relaxation |
| WO2010044101A1 (en) * | 2008-10-08 | 2010-04-22 | V. B. Medicare Pvt. Ltd. | Purification and assay for topoisomerases and use of the assay for screening modulators of topoisomerases |
| KR102798620B1 (ko) * | 2018-06-07 | 2025-04-22 | 암젠 인크 | 단백질-폴리뉴클레오티드 접합체에 대한 검출 검정 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0231955B2 (ja) | 1982-12-07 | 1990-07-17 | Rikagaku Kenkyusho | Kodonochorasenojusuruheikanjodnanochoseiho |
| AU1377099A (en) | 1997-11-03 | 1999-05-24 | Small Molecule Therapeutics, Inc. | Methods and compositions for modulation of bacterial topoisomerase enzymes |
| DE19753182A1 (de) | 1997-11-21 | 1999-07-29 | Claas Junghans | Topologisch fixierte matrixgebundene Nukleinsäure |
| US5998152A (en) | 1998-03-09 | 1999-12-07 | Tularik Inc. | High-throughput screening assays for modulators of nucleic acid topoisomerases |
| JP2002507433A (ja) | 1998-03-25 | 2002-03-12 | ザ プロクター アンド ギャンブル カンパニー | トポイソメラーゼ阻害剤用蛍光アッセイ |
| US6420115B1 (en) | 1999-12-21 | 2002-07-16 | Ingeneus Corporation | Cation mediated triplex hybridization assay |
| US6620588B1 (en) | 2000-05-31 | 2003-09-16 | Salk Institute For Biological Studies | Method of identifying inhibitors of topoisomerase DNA religation |
| AU2001270098A1 (en) | 2000-06-22 | 2002-01-02 | San Diego State University Foundation | Recombination modulators and methods for their production and use |
| WO2003012124A2 (en) | 2001-07-31 | 2003-02-13 | New York Institute Of Technology | Methods for immobilizing molecules to a solid phase and uses thereof |
| US20040022764A1 (en) * | 2002-07-31 | 2004-02-05 | Hanan Polansky | Inhibition of microcompetition with a foreign polynucleotide as treatment of chronic disease |
| FR2852606A1 (fr) | 2003-03-18 | 2004-09-24 | Inst Nat Sante Rech Med | Moyens pour inhiber simultanement l'expression de plusieurs genes impliques dans une pathologie |
| WO2004087963A1 (en) | 2003-03-31 | 2004-10-14 | Astrazeneca Ab | Topoisomerase modulator assays |
-
2004
- 2004-11-11 GB GB0424953A patent/GB0424953D0/en not_active Ceased
-
2005
- 2005-11-10 CA CA002586534A patent/CA2586534A1/en not_active Abandoned
- 2005-11-10 AT AT05803594T patent/ATE454475T1/de not_active IP Right Cessation
- 2005-11-10 AU AU2005303599A patent/AU2005303599A1/en not_active Abandoned
- 2005-11-10 WO PCT/GB2005/004346 patent/WO2006051303A1/en not_active Ceased
- 2005-11-10 EP EP05803594A patent/EP1812592B1/de not_active Expired - Lifetime
- 2005-11-10 DE DE602005018808T patent/DE602005018808D1/de not_active Expired - Lifetime
- 2005-11-10 US US11/718,978 patent/US7838230B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005018808D1 (de) | 2010-02-25 |
| EP1812592A1 (de) | 2007-08-01 |
| WO2006051303A1 (en) | 2006-05-18 |
| GB0424953D0 (en) | 2004-12-15 |
| AU2005303599A1 (en) | 2006-05-18 |
| WO2006051303A8 (en) | 2007-07-26 |
| EP1812592B1 (de) | 2010-01-06 |
| US7838230B2 (en) | 2010-11-23 |
| US20080026388A1 (en) | 2008-01-31 |
| CA2586534A1 (en) | 2006-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |