ATE454475T1 - Gerät zur messung der fähigkeit eines enzyms zur modifizierung der supercoil-topologie von nukleinsäuren sowie modulatoren - Google Patents

Gerät zur messung der fähigkeit eines enzyms zur modifizierung der supercoil-topologie von nukleinsäuren sowie modulatoren

Info

Publication number
ATE454475T1
ATE454475T1 AT05803594T AT05803594T ATE454475T1 AT E454475 T1 ATE454475 T1 AT E454475T1 AT 05803594 T AT05803594 T AT 05803594T AT 05803594 T AT05803594 T AT 05803594T AT E454475 T1 ATE454475 T1 AT E454475T1
Authority
AT
Austria
Prior art keywords
nucleic acid
enzyme
target nucleic
topology
modulators
Prior art date
Application number
AT05803594T
Other languages
English (en)
Inventor
Anthony Maxwell
Original Assignee
Plant Bioscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plant Bioscience Ltd filed Critical Plant Bioscience Ltd
Application granted granted Critical
Publication of ATE454475T1 publication Critical patent/ATE454475T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Saccharide Compounds (AREA)
AT05803594T 2004-11-11 2005-11-10 Gerät zur messung der fähigkeit eines enzyms zur modifizierung der supercoil-topologie von nukleinsäuren sowie modulatoren ATE454475T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0424953A GB0424953D0 (en) 2004-11-11 2004-11-11 Assay
PCT/GB2005/004346 WO2006051303A1 (en) 2004-11-11 2005-11-10 Assay for measuring an enzyme’s capability to modify supercoil topology of nucleic acids and modulators

Publications (1)

Publication Number Publication Date
ATE454475T1 true ATE454475T1 (de) 2010-01-15

Family

ID=33523584

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05803594T ATE454475T1 (de) 2004-11-11 2005-11-10 Gerät zur messung der fähigkeit eines enzyms zur modifizierung der supercoil-topologie von nukleinsäuren sowie modulatoren

Country Status (8)

Country Link
US (1) US7838230B2 (de)
EP (1) EP1812592B1 (de)
AT (1) ATE454475T1 (de)
AU (1) AU2005303599A1 (de)
CA (1) CA2586534A1 (de)
DE (1) DE602005018808D1 (de)
GB (1) GB0424953D0 (de)
WO (1) WO2006051303A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009037511A1 (en) * 2007-09-21 2009-03-26 Astrazeneca Ab Assay for dna supercoiling/relaxation
WO2009037510A1 (en) * 2007-09-21 2009-03-26 Astrazeneca Ab Dna decatenation assay 997
WO2010044101A1 (en) * 2008-10-08 2010-04-22 V. B. Medicare Pvt. Ltd. Purification and assay for topoisomerases and use of the assay for screening modulators of topoisomerases
KR102798620B1 (ko) * 2018-06-07 2025-04-22 암젠 인크 단백질-폴리뉴클레오티드 접합체에 대한 검출 검정

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0231955B2 (ja) 1982-12-07 1990-07-17 Rikagaku Kenkyusho Kodonochorasenojusuruheikanjodnanochoseiho
WO1999023244A1 (en) 1997-11-03 1999-05-14 Small Molecule Therapeutics, Inc. Methods and compositions for modulation of bacterial topoisomerase enzymes
DE19753182A1 (de) * 1997-11-21 1999-07-29 Claas Junghans Topologisch fixierte matrixgebundene Nukleinsäure
US5998152A (en) 1998-03-09 1999-12-07 Tularik Inc. High-throughput screening assays for modulators of nucleic acid topoisomerases
IL138532A0 (en) * 1998-03-25 2001-10-31 Procter & Gamble Fluorescent assay for topoisomerase inhibitors
US6420115B1 (en) * 1999-12-21 2002-07-16 Ingeneus Corporation Cation mediated triplex hybridization assay
US6620588B1 (en) 2000-05-31 2003-09-16 Salk Institute For Biological Studies Method of identifying inhibitors of topoisomerase DNA religation
CA2412513A1 (en) 2000-06-22 2001-12-27 San Diego State University Foundation Modulators of recombination and methods for producing and using the same
EP1421201A4 (de) * 2001-07-31 2005-11-23 New York Inst Techn Verfahren zur immobilisierung von molekülen and eine festphase sowie verwendungen davon
US20040022764A1 (en) * 2002-07-31 2004-02-05 Hanan Polansky Inhibition of microcompetition with a foreign polynucleotide as treatment of chronic disease
FR2852606A1 (fr) * 2003-03-18 2004-09-24 Inst Nat Sante Rech Med Moyens pour inhiber simultanement l'expression de plusieurs genes impliques dans une pathologie
EP1608779A1 (de) 2003-03-31 2005-12-28 AstraZeneca AB Topoisomerasemodulator-assays

Also Published As

Publication number Publication date
US20080026388A1 (en) 2008-01-31
EP1812592B1 (de) 2010-01-06
DE602005018808D1 (de) 2010-02-25
EP1812592A1 (de) 2007-08-01
WO2006051303A1 (en) 2006-05-18
GB0424953D0 (en) 2004-12-15
AU2005303599A1 (en) 2006-05-18
WO2006051303A8 (en) 2007-07-26
US7838230B2 (en) 2010-11-23
CA2586534A1 (en) 2006-05-18

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