ATE454900T1 - Stabilisierung von proteinen in lösung - Google Patents

Stabilisierung von proteinen in lösung

Info

Publication number
ATE454900T1
ATE454900T1 AT04734213T AT04734213T ATE454900T1 AT E454900 T1 ATE454900 T1 AT E454900T1 AT 04734213 T AT04734213 T AT 04734213T AT 04734213 T AT04734213 T AT 04734213T AT E454900 T1 ATE454900 T1 AT E454900T1
Authority
AT
Austria
Prior art keywords
wall portion
coated glass
cycloolefin
polymers
protein
Prior art date
Application number
AT04734213T
Other languages
English (en)
Inventor
Michael Jensen
Birthe Hansen
Troels Kornfelt
Kirsten Jakobsen
Original Assignee
Novo Nordisk Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34973305&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE454900(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk Healthcare Ag filed Critical Novo Nordisk Healthcare Ag
Application granted granted Critical
Publication of ATE454900T1 publication Critical patent/ATE454900T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F110/00Homopolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4846Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00Rigid or semi-rigid containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material or by deep-drawing operations performed on sheet material
    • B65D1/02Bottles or similar containers with necks or like restricted apertures, designed for pouring contents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Ceramic Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
AT04734213T 2003-05-23 2004-05-21 Stabilisierung von proteinen in lösung ATE454900T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200300788 2003-05-23
US47628003P 2003-06-05 2003-06-05

Publications (1)

Publication Number Publication Date
ATE454900T1 true ATE454900T1 (de) 2010-01-15

Family

ID=34973305

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04734213T ATE454900T1 (de) 2003-05-23 2004-05-21 Stabilisierung von proteinen in lösung

Country Status (13)

Country Link
US (1) US8536127B2 (de)
EP (1) EP1628677B1 (de)
JP (2) JP5627832B2 (de)
KR (1) KR20060015574A (de)
CN (1) CN1780638B (de)
AT (1) ATE454900T1 (de)
AU (1) AU2004241698A1 (de)
BR (1) BRPI0409936A (de)
CA (1) CA2525224A1 (de)
DE (1) DE602004025100D1 (de)
MX (1) MXPA05012476A (de)
RU (1) RU2364609C2 (de)
WO (1) WO2004103398A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
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EP1458408B1 (de) 2001-12-21 2009-04-15 Novo Nordisk Health Care AG Flüssige zusammensetzung aus faktor vii polypeptiden
US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
CN1671410B (zh) * 2002-06-21 2010-05-12 诺和诺德医疗保健公司 因子ⅶ多肽的稳定化固体组合物
US7897734B2 (en) * 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
RU2364609C2 (ru) * 2003-05-23 2009-08-20 Ново Нордиск Хелт Кэр Аг Стабилизация белка в растворе
WO2005002615A1 (en) * 2003-07-01 2005-01-13 Novo Nordisk Health Care Ag Liquid, aqueous pharmaceutical composition of factor vii polypeptides
JP5653572B2 (ja) * 2003-08-14 2015-01-14 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 第vii因子ポリペプチドの液状水性医薬組成物
CN1917861B (zh) * 2003-12-19 2012-03-21 诺和诺德医疗保健公司 因子vii多肽的稳定化固体组合物
US20070041905A1 (en) * 2005-08-19 2007-02-22 Hoffman Rebecca S Method of treating depression using a TNF-alpha antibody
CN104887620A (zh) * 2007-05-02 2015-09-09 诺沃—诺迪斯克保健股份有限公司 包括芳香族防腐剂和抗氧化剂的高浓度因子vii多肽制剂
KR101140483B1 (ko) 2007-05-02 2012-07-11 에프. 호프만-라 로슈 아게 단백질을 안정화시키는 방법
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US8420081B2 (en) * 2007-11-30 2013-04-16 Abbvie, Inc. Antibody formulations and methods of making same
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US8883979B2 (en) 2012-08-31 2014-11-11 Bayer Healthcare Llc Anti-prolactin receptor antibody formulations
CN107063940B (zh) 2016-02-10 2019-10-18 贝克顿迪金森法国公司 用于评价基于蛋白质的制剂的稳定性的方法
WO2018181531A1 (ja) 2017-03-29 2018-10-04 テルモ株式会社 プレフィルドシリンジ包装体
EP3760220B1 (de) 2018-02-28 2025-02-19 Seikagaku Corporation Packung mit chondroitinase abc und verfahren zur herstellung davon
CN114980851A (zh) * 2020-01-28 2022-08-30 日本瑞翁株式会社 预填充药剂包装和预填充药剂包装的制造方法
WO2024214811A1 (ja) * 2023-04-14 2024-10-17 中外製薬株式会社 タンパク質含有医薬製剤の安定化方法

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Also Published As

Publication number Publication date
CN1780638A (zh) 2006-05-31
KR20060015574A (ko) 2006-02-17
JP2007502310A (ja) 2007-02-08
AU2004241698A1 (en) 2004-12-02
DE602004025100D1 (de) 2010-03-04
WO2004103398A1 (en) 2004-12-02
CA2525224A1 (en) 2004-12-02
RU2364609C2 (ru) 2009-08-20
MXPA05012476A (es) 2006-02-22
RU2005140282A (ru) 2006-07-27
JP2012229230A (ja) 2012-11-22
EP1628677B1 (de) 2010-01-13
US20060160720A1 (en) 2006-07-20
BRPI0409936A (pt) 2006-04-25
EP1628677A1 (de) 2006-03-01
CN1780638B (zh) 2010-04-14
US8536127B2 (en) 2013-09-17
JP5627832B2 (ja) 2014-11-19

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