ATE455118T1 - Chemisches zwischenprodukt - Google Patents

Chemisches zwischenprodukt

Info

Publication number
ATE455118T1
ATE455118T1 AT03751697T AT03751697T ATE455118T1 AT E455118 T1 ATE455118 T1 AT E455118T1 AT 03751697 T AT03751697 T AT 03751697T AT 03751697 T AT03751697 T AT 03751697T AT E455118 T1 ATE455118 T1 AT E455118T1
Authority
AT
Austria
Prior art keywords
aryl
optionally substituted
chemical intermediate
halo
cyano
Prior art date
Application number
AT03751697T
Other languages
English (en)
Inventor
David Cladingboel
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE455118T1 publication Critical patent/ATE455118T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT03751697T 2002-10-14 2003-10-13 Chemisches zwischenprodukt ATE455118T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0223712.1A GB0223712D0 (en) 2002-10-14 2002-10-14 Chemical intermediate
PCT/SE2003/001594 WO2004035592A1 (en) 2002-10-14 2003-10-13 Chemical intermediate

Publications (1)

Publication Number Publication Date
ATE455118T1 true ATE455118T1 (de) 2010-01-15

Family

ID=9945773

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03751697T ATE455118T1 (de) 2002-10-14 2003-10-13 Chemisches zwischenprodukt

Country Status (25)

Country Link
US (2) US7314931B2 (de)
EP (1) EP1554285B1 (de)
JP (1) JP4476810B2 (de)
KR (1) KR20050056239A (de)
CN (1) CN1319976C (de)
AT (1) ATE455118T1 (de)
AU (1) AU2003269768B2 (de)
BR (1) BR0315112A (de)
CA (1) CA2501413A1 (de)
DE (1) DE60330982D1 (de)
DK (1) DK1554285T3 (de)
ES (1) ES2337998T3 (de)
GB (1) GB0223712D0 (de)
IL (1) IL167778A (de)
IS (1) IS7841A (de)
MX (1) MXPA05003812A (de)
NO (1) NO20051627L (de)
NZ (1) NZ539371A (de)
PL (1) PL375100A1 (de)
PT (1) PT1554285E (de)
RU (1) RU2326122C2 (de)
SI (1) SI1554285T1 (de)
UA (1) UA79986C2 (de)
WO (1) WO2004035592A1 (de)
ZA (1) ZA200502579B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR030756A1 (es) * 2000-10-02 2003-09-03 Astrazeneca Ab Compuesto de oxabispidina util en el tratamiento de arritmias cardiacas
GB0223712D0 (en) * 2002-10-14 2002-11-20 Astrazeneca Ab Chemical intermediate
SE0401539D0 (sv) 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
JP2008543750A (ja) * 2005-06-13 2008-12-04 アストラゼネカ アクチボラグ 心不整脈の処置用の新規オキサビスピジン化合物
US20100222335A1 (en) * 2005-06-20 2010-09-02 Astrazeneca Ab Process For The Preparation Of N,N'-Disubstituted Oxabispidines
WO2006137772A1 (en) * 2005-06-20 2006-12-28 Astrazeneca Ab New physical form of n,n´- disubstituted oxabispidines
CA2610093A1 (en) * 2005-06-20 2006-12-28 Astrazeneca Ab Process for the preparation of sulfonic acid salts of oxabispidines
AR054391A1 (es) * 2005-06-20 2007-06-20 Astrazeneca Ab Procedimiento para la preparacion de 3,7- dihidroxi-1,5-diazaciclooctanos
TW200734342A (en) * 2005-12-15 2007-09-16 Astrazeneca Ab New compounds for the treatment of cardiac arrhythmias
SG10201802911RA (en) 2013-03-15 2018-05-30 Global Blood Therapeutics Inc Compounds and uses thereof for the modulation of hemoglobin
EA202092627A1 (ru) 2013-11-18 2021-09-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
TWI773657B (zh) 2015-12-18 2022-08-11 美商亞德利克斯公司 作爲非全身tgr5促效劑之經取代之4-苯基吡啶化合物
US12084472B2 (en) 2015-12-18 2024-09-10 Ardelyx, Inc. Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903759D0 (sv) 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
AR030756A1 (es) * 2000-10-02 2003-09-03 Astrazeneca Ab Compuesto de oxabispidina util en el tratamiento de arritmias cardiacas
SE0101324D0 (sv) 2001-04-12 2001-04-12 Astrazeneca Ab New process
GB0223712D0 (en) * 2002-10-14 2002-11-20 Astrazeneca Ab Chemical intermediate

Also Published As

Publication number Publication date
CN1319976C (zh) 2007-06-06
US20060199814A1 (en) 2006-09-07
EP1554285B1 (de) 2010-01-13
JP4476810B2 (ja) 2010-06-09
UA79986C2 (en) 2007-08-10
EP1554285A1 (de) 2005-07-20
IL167778A (en) 2010-04-29
HK1078861A1 (en) 2006-03-24
HK1082498A1 (en) 2006-06-09
GB0223712D0 (en) 2002-11-20
US7314931B2 (en) 2008-01-01
MXPA05003812A (es) 2005-06-08
SI1554285T1 (sl) 2010-04-30
BR0315112A (pt) 2005-08-16
DK1554285T3 (da) 2010-04-19
ZA200502579B (en) 2006-02-22
KR20050056239A (ko) 2005-06-14
RU2326122C2 (ru) 2008-06-10
DE60330982D1 (de) 2010-03-04
ES2337998T3 (es) 2010-05-03
WO2004035592A1 (en) 2004-04-29
NZ539371A (en) 2006-10-27
US20090062532A1 (en) 2009-03-05
IS7841A (is) 2005-05-12
CN1705671A (zh) 2005-12-07
AU2003269768A1 (en) 2004-05-04
JP2006505565A (ja) 2006-02-16
NO20051627L (no) 2005-05-06
CA2501413A1 (en) 2004-04-29
PT1554285E (pt) 2010-03-08
RU2005109158A (ru) 2006-01-20
AU2003269768B2 (en) 2007-08-23
PL375100A1 (en) 2005-11-14

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