ATE457736T1 - Zusammensetzung aus einem pulmonalen surfactant und einem von tnf stammenden peptid - Google Patents

Zusammensetzung aus einem pulmonalen surfactant und einem von tnf stammenden peptid

Info

Publication number
ATE457736T1
ATE457736T1 AT05767969T AT05767969T ATE457736T1 AT E457736 T1 ATE457736 T1 AT E457736T1 AT 05767969 T AT05767969 T AT 05767969T AT 05767969 T AT05767969 T AT 05767969T AT E457736 T1 ATE457736 T1 AT E457736T1
Authority
AT
Austria
Prior art keywords
tnf
composition
pulmonary surfactant
peptide derived
pulmonary
Prior art date
Application number
AT05767969T
Other languages
English (en)
Inventor
Klaus P Schaefer
Stefan-Lutz Wollin
Ingeborg Muehldorfer
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Application granted granted Critical
Publication of ATE457736T1 publication Critical patent/ATE457736T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0082—Lung surfactant, artificial mucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
AT05767969T 2004-08-06 2005-07-27 Zusammensetzung aus einem pulmonalen surfactant und einem von tnf stammenden peptid ATE457736T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04103808 2004-08-06
PCT/EP2005/053672 WO2006013183A1 (en) 2004-08-06 2005-07-27 Composition comprising a pulmonary surfactant and a tnf-derived peptide

Publications (1)

Publication Number Publication Date
ATE457736T1 true ATE457736T1 (de) 2010-03-15

Family

ID=34929426

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05767969T ATE457736T1 (de) 2004-08-06 2005-07-27 Zusammensetzung aus einem pulmonalen surfactant und einem von tnf stammenden peptid

Country Status (9)

Country Link
US (1) US8236750B2 (de)
EP (1) EP1781323B1 (de)
JP (1) JP5108515B2 (de)
AT (1) ATE457736T1 (de)
AU (1) AU2005268755B2 (de)
CA (1) CA2575513C (de)
DE (1) DE602005019416D1 (de)
ES (1) ES2339954T3 (de)
WO (1) WO2006013183A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008036293A1 (en) * 2006-09-19 2008-03-27 Discovery Laboratories, Inc. Pulmonary surfactant formulations and methods for promoting mucus clearance
EP2009023A1 (de) * 2007-06-04 2008-12-31 Rentschler Beteiligungs GmbH Neuartige Peptide und ihre Verwendung bei der Behandlung von Ödemen
AT507953B1 (de) * 2009-03-05 2011-02-15 Apeptico Forschung & Entwicklung Gmbh Verfahren zur vermeidung und zur behandlung einer hyperpermeabilität
AT509267A1 (de) 2010-01-14 2011-07-15 Apeptico Forschung & Entwicklung Gmbh Organische verbindungen zur regulierung von vektoriellen ionenkanälen
ES2542227T3 (es) * 2010-06-21 2015-08-03 Apeptico Forschung Und Entwicklung Gmbh Tratamiento de complicaciones vasculares de diabetes
AT510585B1 (de) * 2010-11-18 2012-05-15 Apeptico Forschung & Entwicklung Gmbh Zusammensetzung umfassend ein peptid und ein hemmstoff der viralen neuraminidase
EP2679239A1 (de) * 2012-06-28 2014-01-01 Apeptico Forschung und Entwicklung GmbH Pharmazeutische Zusammensetzung zur Behandlung der durch Sauerstoffarmut und verringerten Luftdruck vermittelten pulmonalen Form der Höhenkrankheit
ES2813379T3 (es) * 2013-04-23 2021-03-23 Apeptico Forschung & Entwicklung Gmbh Tratamiento extracorporal del pulmón con un péptido cíclico de formula x1-gqretpegaeakpwy-x2
US12004506B2 (en) 2013-04-23 2024-06-11 Apeptico Forschung Und Entwicklung Gmbh Pharmaceutical composition comprising a cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2 and use for extracorporeal lung treatment
EP2988768B1 (de) * 2013-04-23 2021-03-31 APEPTICO Forschung und Entwicklung GmbH Lyophilisat enthaltend ein zyklisches peptid der formel x1-gqretpegaeakpwy-x2 zur behandlung pulmonarer ödeme
US20170014472A1 (en) * 2014-03-04 2017-01-19 Apeptico Forschung Und Entwicklung Gmbh Attenuation of intrapulmonary inflammation
EP3062772B1 (de) * 2014-03-18 2018-01-24 APEPTICO Forschung und Entwicklung GmbH Peptidmedikament in der form eines trockenpulvers
JP2018514545A (ja) * 2015-04-30 2018-06-07 ユニバーシティ オブ ブレーメン 医療用および美容用の新規な皮膚ケア製造物
CN106821982A (zh) * 2017-01-12 2017-06-13 东南大学 一种西那普肽微泡制剂及其制备方法
US20250241978A1 (en) * 2020-05-08 2025-07-31 Apeptico Forschung Und Entwicklung Gmbh Peptide for prevention or treatment of covid-19

Family Cites Families (27)

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Publication number Priority date Publication date Assignee Title
DE3229179C2 (de) 1982-08-05 1986-04-17 A. Nattermann & Cie GmbH, 5000 Köln Lungensurfactant
DE3369644D1 (en) 1982-11-22 1987-03-12 Teijin Ltd Artificial lung surfactant and remedy for respiratory distress syndrome containing it as active principle
JPS59164724A (ja) 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
CS938384A1 (en) 1983-12-08 1990-08-14 Lachmann Burkhardt Pharmaceutical agent for breathlesness therapy and method of its production
US4659805A (en) 1984-12-11 1987-04-21 California Biotechnology, Inc. Recombinant alveolar surfactant protein
US5104853A (en) 1984-12-11 1992-04-14 California Biotechnology Inc. Alveolar surfactant proteins having cys to ser mutations
US4933280A (en) 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
JPS63503222A (ja) 1986-05-06 1988-11-24 サイオス　ノバ　インコーポレイテッド 肺の疎水性界面活性物質に結合した分子量６，０００ダルトンのタンパク質及びその多量体
WO1988003170A1 (en) 1986-10-24 1988-05-05 Whitsett Jeffrey A Pulmonary hydrophobic surfactant-associated proteins
IT1203873B (it) 1987-04-08 1989-02-23 Chiesi Farma Spa Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e
US4944941A (en) * 1987-08-07 1990-07-31 Genentech, Inc. Methods and compositions for the treatment of lung conditions
JP2602968B2 (ja) 1987-11-04 1997-04-23 カリフォルニア バイオテクノロジー インコーポレイテッド 肺胞の界面活性タンパク類
US5164369A (en) 1988-01-06 1992-11-17 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
US5260273A (en) 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
NZ229737A (en) 1988-07-01 1991-05-28 Merrell Dow Pharma Polypeptides and derivatives of them with lung surfactant properties and their preparation
SE8803713D0 (sv) 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
DE4418936A1 (de) 1994-05-31 1996-02-08 Byk Gulden Lomberg Chem Fab Polypeptid
CZ292186B6 (cs) 1996-01-24 2003-08-13 Altana Pharma Ag Způsob výroby práškového prostředku s obsahem plicní povrchově aktivní látky, práškový prostředek a jeho použití
WO1997035882A1 (en) 1996-03-27 1997-10-02 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
DE69835594T2 (de) 1997-02-17 2007-08-16 Altana Pharma Ag Zusammensetzungen zur behandlung von irds oder ards die 3-(cyclopropylmethoxy)-n-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy) benzamid und lungensurfactant enthalten
NZ509604A (en) * 1998-08-14 2003-05-30 Innogenetics N TNF-derived peptides for use in treating oedema
ATE308976T1 (de) 1998-11-10 2005-11-15 Altana Pharma Ag Lungensurfactant zubereitungen enthaltendes behandlungset
DE19851617A1 (de) * 1998-11-10 2000-05-11 Byk Gulden Lomberg Chem Fab Behandlungsset
US20030091509A1 (en) * 2000-02-11 2003-05-15 Haefner Dietrich Novel use of pulmonary surfactant for the prophylaxis and treatment of chronic pulmonary diseases
US20030158087A1 (en) 2000-04-12 2003-08-21 Dietrich Hafner Novel use of fulmonary surfactant for the prophylaxis or early treatment if acute fulmonary diseases
SE0102055D0 (sv) 2001-06-08 2001-06-08 Astrazeneca Ab New Compounds
WO2003033014A2 (de) 2001-10-11 2003-04-24 Altana Pharma Ag Neue verwendung von lungensurfactant

Also Published As

Publication number Publication date
US8236750B2 (en) 2012-08-07
AU2005268755A1 (en) 2006-02-09
CA2575513C (en) 2014-09-16
WO2006013183A1 (en) 2006-02-09
EP1781323B1 (de) 2010-02-17
DE602005019416D1 (de) 2010-04-01
AU2005268755B2 (en) 2011-04-07
JP5108515B2 (ja) 2012-12-26
JP2008509107A (ja) 2008-03-27
EP1781323A1 (de) 2007-05-09
US20070299003A1 (en) 2007-12-27
CA2575513A1 (en) 2006-02-09
ES2339954T3 (es) 2010-05-27

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