ATE457990T1 - Neues verfahren zur herstellung eines cefprozil- zwischenprodukts - Google Patents

Neues verfahren zur herstellung eines cefprozil- zwischenprodukts

Info

Publication number: ATE457990T1
Authority: AT; Austria
Prior art keywords: cefprozil; producing; new process; cephem; acetamido
Prior art date: 2004-11-01

Application number

AT04806740T

Other languages

English (en)

Inventor

Reddy Bandi Parthasaradhi

Reddy K Rathnakar

Reddy R Raji

Reddy D Muralidhara

Nagabelli Murali

Original Assignee

Hetero Drugs Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-11-01

Filing date

2004-11-01

Publication date

2010-03-15

2004-11-01 Application filed by Hetero Drugs Ltd filed Critical Hetero Drugs Ltd

2010-03-15 Application granted granted Critical

2010-03-15 Publication of ATE457990T1 publication Critical patent/ATE457990T1/de

Links

WDLWHQDACQUCJR-ZAMMOSSLSA-N (6r,7r)-7-[[(2r)-2-azaniumyl-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(e)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)/C=C/C)C(O)=O)=CC=C(O)C=C1 WDLWHQDACQUCJR-ZAMMOSSLSA-N 0.000 title abstract 2
229960002580 cefprozil Drugs 0.000 title abstract 2
WDLWHQDACQUCJR-WTBJWPOVSA-N (6r,7r)-7-[[2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(z)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical compound N([C@H]1[C@@H]2N(C1=O)C(=C(CS2)\C=C/C)C(O)=O)C(=O)C(N)C1=CC=C(O)C=C1 WDLWHQDACQUCJR-WTBJWPOVSA-N 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/188—Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Magnetic Heads (AREA)

AT04806740T 2004-11-01 2004-11-01 Neues verfahren zur herstellung eines cefprozil- zwischenprodukts ATE457990T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/IN2004/000337 WO2006048887A1 (en)	2004-11-01	2004-11-01	A novel process for preparation of cefprozil intermediate

Publications (1)

Publication Number	Publication Date
ATE457990T1 true ATE457990T1 (de)	2010-03-15

Family

ID=36318935

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04806740T ATE457990T1 (de)	2004-11-01	2004-11-01	Neues verfahren zur herstellung eines cefprozil- zwischenprodukts

Country Status (7)

Country	Link
US (2)	US20080281093A1 (de)
EP (2)	EP2213676A1 (de)
AT (1)	ATE457990T1 (de)
DE (1)	DE602004025631D1 (de)
ES (1)	ES2338335T3 (de)
PL (1)	PL1809638T3 (de)
WO (1)	WO2006048887A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7230097B2 (en) *	2003-03-10	2007-06-12	Lupin Ltd.	Process for preparation of 7-[α-Amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid
PL1809638T3 (pl)	2004-11-01	2010-07-30	Hetero Drugs Ltd	Nowy sposób wytwarzania związków pośrednich w syntezie cefprozilu
CN102408438B (zh) *	2010-09-26	2015-01-07	石药集团中奇制药技术（石家庄）有限公司	一种头孢丙烯一水合物的制备方法
CN102911187B (zh) *	2012-10-11	2015-03-11	南通康鑫药业有限公司	一种头孢丙烯的回收方法
CN103910749B (zh) *	2014-03-14	2016-06-29	中节能万润股份有限公司	一种盐酸头孢替安的制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2215939B1 (de) *	1973-01-31	1976-07-02	Roussel Uclaf
GB1505345A (en) *	1974-04-10	1978-03-30	Beecham Group Ltd	Cephalosporins
US4148817A (en) *	1976-03-25	1979-04-10	Eli Lilly And Company	Process and intermediates for preparing cephalosporin antibiotics
IT1065387B (it) *	1976-12-16	1985-02-25	Dobfar Spa	Proccedimento per la preparazione di cefalosporine
KR820001564B1 (ko) *	1981-05-09	1982-09-02	동신제약 주식회사	새로운 실릴화제를 이용한 세팔로스포린 유도체의 제조방법
US4520022A (en) *	1983-01-28	1985-05-28	Bristol-Myers Company	Substituted vinyl cephalosporins
US4699979A (en) *	1985-04-22	1987-10-13	Bristol-Meyers Company	7-amino-3-propenylcephalosporanic acid and esters thereof
FR2580652B1 (fr) *	1985-04-22	1989-01-06	Bristol Myers Co	Acide 7-amino-3-propenylcephalosporanique et ses esters
US4694079A (en)	1985-07-29	1987-09-15	Bristol-Myers Company	3-propenyl cephalosporin solvates
US4727070A (en) *	1985-11-25	1988-02-23	Bristol-Myers Company	3-Propenzl cephalosporin isomer separation process and derivative
GB9115203D0 (en) *	1991-07-15	1991-08-28	Biochemie Gmbh	Improvements in or relating to beta lactam production
TW555855B (en)	1996-07-26	2003-10-01	Bristol Myers Squibb Co	Synthesis of beta-lactam antibacterials using soluble side chain esters and enzyme acylase
GB0118764D0 (en) *	2001-08-01	2001-09-26	Biochemie Gmbh	Organic compounds
US6903211B2 (en) *	2002-10-30	2005-06-07	Orchid Chemicals & Pharmaceuticals Limited	Process for the preparation of 3-propenyl cephalosporin DMF solvate
US7230097B2 (en) *	2003-03-10	2007-06-12	Lupin Ltd.	Process for preparation of 7-[α-Amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid
WO2004083172A2 (en) *	2003-03-21	2004-09-30	Ranbaxy Laboratories Limited	Process for the preparation of 7-amino (p-hydroxyphenylglyclyamido) cephem compounds
PL1809638T3 (pl)	2004-11-01	2010-07-30	Hetero Drugs Ltd	Nowy sposób wytwarzania związków pośrednich w syntezie cefprozilu

2004
- 2004-11-01 PL PL04806740T patent/PL1809638T3/pl unknown
- 2004-11-01 EP EP09177637A patent/EP2213676A1/de not_active Withdrawn
- 2004-11-01 ES ES04806740T patent/ES2338335T3/es not_active Expired - Lifetime
- 2004-11-01 WO PCT/IN2004/000337 patent/WO2006048887A1/en not_active Ceased
- 2004-11-01 DE DE602004025631T patent/DE602004025631D1/de not_active Expired - Lifetime
- 2004-11-01 EP EP04806740A patent/EP1809638B1/de not_active Expired - Lifetime
- 2004-11-01 AT AT04806740T patent/ATE457990T1/de not_active IP Right Cessation
- 2004-11-01 US US10/595,544 patent/US20080281093A1/en not_active Abandoned
2008
- 2008-10-24 US US12/257,738 patent/US7629482B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP2213676A1 (de)	2010-08-04
US7629482B2 (en)	2009-12-08
US20080281093A1 (en)	2008-11-13
WO2006048887A1 (en)	2006-05-11
DE602004025631D1 (de)	2010-04-01
PL1809638T3 (pl)	2010-07-30
ES2338335T3 (es)	2010-05-06
EP1809638B1 (de)	2010-02-17
US20090048460A1 (en)	2009-02-19
EP1809638A1 (de)	2007-07-25

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2010-08-15

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