ATE460671T1 - Identifikation von arzneimittel gegen mykobakterien - Google Patents
Identifikation von arzneimittel gegen mykobakterienInfo
- Publication number
- ATE460671T1 ATE460671T1 AT03751127T AT03751127T ATE460671T1 AT E460671 T1 ATE460671 T1 AT E460671T1 AT 03751127 T AT03751127 T AT 03751127T AT 03751127 T AT03751127 T AT 03751127T AT E460671 T1 ATE460671 T1 AT E460671T1
- Authority
- AT
- Austria
- Prior art keywords
- rv2027c
- devr
- devs
- degree
- single domain
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 3
- 101100278329 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) dosT gene Proteins 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000030609 dephosphorylation Effects 0.000 abstract 2
- 238000006209 dephosphorylation reaction Methods 0.000 abstract 2
- 230000035578 autophosphorylation Effects 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41883702P | 2002-10-16 | 2002-10-16 | |
| PCT/IB2003/004555 WO2004036224A2 (en) | 2002-10-16 | 2003-10-16 | Screening method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE460671T1 true ATE460671T1 (de) | 2010-03-15 |
Family
ID=32107981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03751127T ATE460671T1 (de) | 2002-10-16 | 2003-10-16 | Identifikation von arzneimittel gegen mykobakterien |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7566550B2 (de) |
| EP (1) | EP1554586B1 (de) |
| CN (1) | CN100554966C (de) |
| AT (1) | ATE460671T1 (de) |
| AU (1) | AU2003269346A1 (de) |
| DE (1) | DE60331669D1 (de) |
| WO (1) | WO2004036224A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8795978B2 (en) * | 2007-06-22 | 2014-08-05 | The Uab Research Foundation | Modulating latency and reactivation of Mycobacterium tuberculosis |
| KR101574332B1 (ko) * | 2008-06-17 | 2015-12-08 | 재단법인 한국파스퇴르연구소 | 항감염성 화합물 |
| WO2012002239A1 (ja) * | 2010-06-29 | 2012-01-05 | 独立行政法人産業技術総合研究所 | ハロゲン化物の検出剤、並びにそれを検出する方法及び検出センサー |
| EP3050565A1 (de) * | 2015-01-27 | 2016-08-03 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Benzimidazolschwefelderivate zur Vorbeugung oder Behandlung von Tuberkulose |
| WO2016182819A2 (en) * | 2015-05-05 | 2016-11-17 | William Marsh Rice University | Identifying ligands from bacterial sensors |
| WO2020202188A1 (en) * | 2019-03-29 | 2020-10-08 | Indian Institute Of Science | In-vitro processes for screening candidate molecules |
| EP3953686A4 (de) * | 2019-04-09 | 2022-12-21 | Agency for Science, Technology and Research | Markierungsfreie detektion von mycobakterien mittels oberflächenverstärkter raman-spektroskopie |
| CN115312136B (zh) * | 2022-06-20 | 2025-10-28 | 军事科学院军事医学研究院环境医学与作业医学研究所 | 一种环境双酚类污染物生态风险的评价模型的构建方法和评价方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4975280A (en) * | 1989-01-23 | 1990-12-04 | Ethyl Corporation | Bioerodable sustained release implants |
| US6043045A (en) * | 1996-09-12 | 2000-03-28 | The Scripps Research Institute | Screening methods for the identification of novel antibiotics |
| US6162627A (en) | 1998-03-19 | 2000-12-19 | University Of Medicine And Dentistry Of New Jersey | Methods of identifying inhibitors of sensor histidine kinases through rational drug design |
| GB0030368D0 (en) * | 2000-12-13 | 2001-01-24 | Inst Of Molecul & Cell Biology | Dormancy-induced mycobacterium proteins |
| GB2398302B (en) | 2002-02-08 | 2005-10-19 | All India Inst Med | A process for identifying a novel target for use for the development of therapeutic modalities and drugs effective against tuberculosis |
-
2003
- 2003-10-16 AT AT03751127T patent/ATE460671T1/de not_active IP Right Cessation
- 2003-10-16 US US10/687,402 patent/US7566550B2/en not_active Expired - Lifetime
- 2003-10-16 EP EP03751127A patent/EP1554586B1/de not_active Expired - Lifetime
- 2003-10-16 AU AU2003269346A patent/AU2003269346A1/en not_active Abandoned
- 2003-10-16 CN CNB2003801045391A patent/CN100554966C/zh not_active Expired - Lifetime
- 2003-10-16 DE DE60331669T patent/DE60331669D1/de not_active Expired - Lifetime
- 2003-10-16 WO PCT/IB2003/004555 patent/WO2004036224A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US7566550B2 (en) | 2009-07-28 |
| WO2004036224A3 (en) | 2004-09-02 |
| AU2003269346A8 (en) | 2004-05-04 |
| EP1554586B1 (de) | 2010-03-10 |
| EP1554586A2 (de) | 2005-07-20 |
| WO2004036224A2 (en) | 2004-04-29 |
| DE60331669D1 (de) | 2010-04-22 |
| US20040209319A1 (en) | 2004-10-21 |
| CN100554966C (zh) | 2009-10-28 |
| AU2003269346A1 (en) | 2004-05-04 |
| CN1754100A (zh) | 2006-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |