ATE461283T1 - Neue vollständige genomische rna des japanenzephalitis-virus, infektiöse jev cdna daraus und deren verwendung - Google Patents

Neue vollständige genomische rna des japanenzephalitis-virus, infektiöse jev cdna daraus und deren verwendung

Info

Publication number
ATE461283T1
ATE461283T1 AT03748780T AT03748780T ATE461283T1 AT E461283 T1 ATE461283 T1 AT E461283T1 AT 03748780 T AT03748780 T AT 03748780T AT 03748780 T AT03748780 T AT 03748780T AT E461283 T1 ATE461283 T1 AT E461283T1
Authority
AT
Austria
Prior art keywords
jev
genomic rna
infectious
virus
japanese
Prior art date
Application number
AT03748780T
Other languages
English (en)
Inventor
Seung Han Lee
Young-Min Lee
Sang-Im Yun
Original Assignee
Cid Co Ltd
Seung Han Lee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cid Co Ltd, Seung Han Lee filed Critical Cid Co Ltd
Application granted granted Critical
Publication of ATE461283T1 publication Critical patent/ATE461283T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/20—Pseudochromosomes, minichrosomosomes
    • C12N2800/204—Pseudochromosomes, minichrosomosomes of bacterial origin, e.g. BAC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT03748780T 2002-10-09 2003-10-09 Neue vollständige genomische rna des japanenzephalitis-virus, infektiöse jev cdna daraus und deren verwendung ATE461283T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20020061589 2002-10-09
PCT/KR2003/002081 WO2004033690A1 (en) 2002-10-09 2003-10-09 Novel full-length genomic rna of japanese encephalitis virus, infectious jev cdna therefrom, and use thereof

Publications (1)

Publication Number Publication Date
ATE461283T1 true ATE461283T1 (de) 2010-04-15

Family

ID=36947533

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03748780T ATE461283T1 (de) 2002-10-09 2003-10-09 Neue vollständige genomische rna des japanenzephalitis-virus, infektiöse jev cdna daraus und deren verwendung

Country Status (11)

Country Link
US (1) US7811579B2 (de)
EP (1) EP1556493B1 (de)
JP (1) JP4430543B2 (de)
KR (1) KR100710519B1 (de)
CN (1) CN1829796B (de)
AT (1) ATE461283T1 (de)
AU (1) AU2003267851B2 (de)
CA (1) CA2501289A1 (de)
DE (1) DE60331758D1 (de)
RU (1) RU2307872C2 (de)
WO (1) WO2004033690A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100872840B1 (ko) * 2004-07-09 2008-12-22 (주)씨아이디 돼지생식기호흡기증후군 바이러스에 대한 전체-길이의감염성이 있는 cDNA 클론 및 이의 용도
BRPI0504945B8 (pt) * 2005-10-31 2022-08-02 Fundacao Oswaldo Cruz Método para a produção de flavivirus recombinante contendo sequências de nucleotídeos codificantes de uma proteína heteróloga, constructo de dna, flavivirus, e, composição vacinal para imunizar contra flavivirus e/ou outros patógenos.
JP5779352B2 (ja) * 2008-03-14 2015-09-16 サノフィ パスツール バイオロジクス リミテッド ライアビリティ カンパニー 複製欠損フラビウイルスワクチンおよびワクチンベクター
EP2473624B1 (de) * 2009-08-31 2019-05-01 Gen-Probe Incorporated Test für dengue-virus
US9080185B2 (en) * 2010-09-21 2015-07-14 National Defensive Medical Center Recombinant flaviviral constructs and uses thereof
CN102199673A (zh) * 2010-12-24 2011-09-28 中国检验检疫科学研究院 乙型脑炎病毒荧光定量pcr检测新方法及乙型脑炎病毒检测pcr体系
WO2015157730A2 (en) * 2014-04-11 2015-10-15 Young-Min Lee Drug target and construct for japanese encephalitis virus infection
EP3146051B8 (de) * 2014-05-20 2019-11-27 University of Iowa Research Foundation Therapeutische verbindungen für huntington-krankheit
WO2017059902A1 (en) 2015-10-07 2017-04-13 Biontech Rna Pharmaceuticals Gmbh 3' utr sequences for stabilization of rna
CN107937615B (zh) * 2017-12-20 2021-06-25 广东省农业科学院动物卫生研究所 用于区分猪乙型脑炎病毒野毒株和疫苗株的引物和探针
KR102119875B1 (ko) * 2019-03-19 2020-06-05 한국화학연구원 한국형 중동호흡기증후군 코로나바이러스 감염성 변이 유전자 및 이의 용도
CN110840908B (zh) * 2019-10-17 2021-06-01 浙江农林大学 lncRNA NONSUST0067151在抑制乙脑病毒增殖中的应用
CN111334482B (zh) * 2020-03-31 2023-03-14 华南农业大学 一种复制性增强的减毒jev及其制备方法与应用
WO2022015514A1 (en) * 2020-07-13 2022-01-20 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods to enhance rna stability and translation and uses thereof
EP4179112A4 (de) 2020-07-13 2024-11-20 The Board of Trustees of the Leland Stanford Junior University Systeme und verfahren zur beurteilung der rna-stabilität

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988003032A1 (en) * 1986-10-27 1988-05-05 Fournier Maurielle J Diagnosis of and vaccine for japanese encephalitis virus and related viruses
KR100430960B1 (ko) * 1995-05-11 2004-10-28 거번먼트오브더유나이티드스테이츠오브아메리카,애즈리프리젠티드바이더세크러트리오브디아미 매우약독화된재조합일본뇌염바이러스를생성하는감염성일본뇌염바이러스cDNA클론및이의백신
KR0157262B1 (ko) * 1995-12-19 1998-11-16 김태구 차량용 파워 시트에서의 콘솔 박스의 무빙 시스템
KR100252379B1 (ko) * 1997-08-27 2000-04-15 대한민국 한국에서 분리된 일본뇌염 바이러스의 염기서열
IL139844A0 (en) 1998-06-04 2002-02-10 Us Gov Health & Human Serv Nucleic acid vaccines for prevention of flavivirus infection
GB2372991B (en) * 2001-03-09 2004-11-17 Fiocruz Fundacao Oswaldo Cruz Flavivirus expression vector

Also Published As

Publication number Publication date
RU2307872C2 (ru) 2007-10-10
US20060234965A1 (en) 2006-10-19
AU2003267851B2 (en) 2007-07-05
EP1556493B1 (de) 2010-03-17
CN1829796A (zh) 2006-09-06
CA2501289A1 (en) 2004-04-22
RU2005114015A (ru) 2005-12-20
US7811579B2 (en) 2010-10-12
CN1829796B (zh) 2010-05-26
AU2003267851A1 (en) 2004-05-04
WO2004033690A1 (en) 2004-04-22
JP4430543B2 (ja) 2010-03-10
KR100710519B1 (ko) 2007-04-24
EP1556493A4 (de) 2006-04-26
EP1556493A1 (de) 2005-07-27
KR20040032791A (ko) 2004-04-17
DE60331758D1 (de) 2010-04-29
JP2006501841A (ja) 2006-01-19

Similar Documents

Publication Publication Date Title
ATE461283T1 (de) Neue vollständige genomische rna des japanenzephalitis-virus, infektiöse jev cdna daraus und deren verwendung
BR9712592A (pt) Processo para gerar um clone infeccioso, ácido nucléico recombinante, molécula do mesmo, vìrus de rna modificado, célula infectada com o mesmo, vacina, proteìna e/ou antìgeno, e, ensaio diagnóstico
DK0702085T3 (da) Rekombinant infektiøs ikke-segmenteret negativ-strenget RNA-virus
NO990025D0 (no) Hamster-EF-1<alfa> transkripsjonsregulatorisk DNA
DE69536039D1 (de) Wirtszelle enthaltend ein rekombinantes Virus, welches ein Antigen exprimiert und ein rekombinantes Virus, welches ein immunstimulatorisches Molekül exprimiert
DE69334357D1 (de) Nachweis und Typisierung das Hepatitis C Virus (HCV) mittels 5'UTR und NS5 Nukleinsäuresequenzen
WO2005056584A3 (fr) Nouvelle souche de coronavirus associe au sras et ses applications.
ATE553201T1 (de) Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismittel
MX9801715A (es) Secuencia novedosa en el extremo 3' del genoma del virus de la hepatitis c, y su uso en diagnostico y en la preparacion de composiciones terapeuticas.
PT783321E (pt) Sequencia nucleotidica viral vr-2332 e metodos de utilizacao
DE69104380D1 (de) Vom genom des papillomavirus-hpv-39 abgeleitete dns-sequenzen, deren anwendung in der in vitro-diagnose und zur herstellung einer immunogenenzusammensetzung.
BR0016145A (pt) Clones infecciosos
BR0211191A (pt) ensaios baseados em ácido nucléico para se diagnosticar precisamente infecção por parvovìrus b19 e inciadores e marcadores para uso nesses ensaios
WO2004085633A8 (en) A novel human virus causing severe acute respiratory syndrome (sars) and uses thereof
DE69028951D1 (de) Oligonukleotiden-Sequenzen zur Amplifizierung von HIV-2 und SIV Retrovirusgenomen, ihre Verwendung zur In-vitro-Diagnostik von durch diese Viren verursachten Infektionen
DE60034884D1 (de) Klonierte genome von infektiösen hepatitis c viren genotyp 2a und deren verwendungen
ATE408013T1 (de) Infektiöses cdna klon des gb-virus b und dessen verwendungen
AR021143A1 (es) Identificacion de genotipos senv
Mustafa et al. Pandemic SARS Coronavirus-2 infections in humans-COVID-19
ATE414905T1 (de) Diabetesmodell
PT1254663E (pt) Agente antiviral
DE60035680D1 (de) Komplette gensequenz des esel-leukozyten-impfstoffstammes des equinen infektiösen anemievirus und ihre anwendung
ATE481507T1 (de) Primer- und sondenkonstruktion zur effizienten amplifikation und detektion des 3'- nichttranslatierten bereichs von hcv
WO1999052947A3 (en) TRANSFERRIN RECEPTOR GENES OF $i(MORAXELLA)
ATE420210T1 (de) Diagnose des brustkrebsrisikos

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties