ATE462702T1 - Für die behandlung von entzündlichen krankheiten nützliche beta-carboline - Google Patents

Für die behandlung von entzündlichen krankheiten nützliche beta-carboline

Info

Publication number: ATE462702T1
Authority: AT; Austria
Prior art keywords: beta; inflammatory diseases; treatment; useful; carbolines
Prior art date: 2004-04-09

Application number

AT05779267T

Other languages

English (en)

Inventor

Michael Hepperle

Julie Liu

Francois Soucy

Raman Prakash

Jeremy Little

Paul Fleming

Dominic Reynolds

Geraldine Harriman

Original Assignee

Millennium Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-04-09

Filing date

2005-04-08

Publication date

2010-04-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35045213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE462702(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-04-08 Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc

2010-04-15 Application granted granted Critical

2010-04-15 Publication of ATE462702T1 publication Critical patent/ATE462702T1/de

Links

208000027866 inflammatory disease Diseases 0.000 title abstract 2
206010028980 Neoplasm Diseases 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
AIFRHYZBTHREPW-UHFFFAOYSA-N β-carboline Chemical class N1=CC=C2C3=CC=CC=C3NC2=C1 AIFRHYZBTHREPW-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A61P31/08—Antibacterial agents for leprosy
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Physical Education & Sports Medicine (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Immunology (AREA)
Neurology (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Biotechnology (AREA)
Dermatology (AREA)
Obesity (AREA)
Psychiatry (AREA)
AIDS & HIV (AREA)
Endocrinology (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)

AT05779267T 2004-04-09 2005-04-08 Für die behandlung von entzündlichen krankheiten nützliche beta-carboline ATE462702T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US56089204P	2004-04-09	2004-04-09
PCT/US2005/013812 WO2005111037A1 (en)	2004-04-09	2005-04-08	Beta-carbolines useful for treating inflammatory disease

Publications (1)

Publication Number	Publication Date
ATE462702T1 true ATE462702T1 (de)	2010-04-15

Family

ID=35045213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05779267T ATE462702T1 (de)	2004-04-09	2005-04-08	Für die behandlung von entzündlichen krankheiten nützliche beta-carboline

Country Status (23)

Country	Link
US (1)	US7951801B2 (de)
EP (2)	EP2206713A1 (de)
JP (1)	JP2007532582A (de)
KR (1)	KR20070014166A (de)
CN (1)	CN1976931A (de)
AT (1)	ATE462702T1 (de)
AU (1)	AU2005243188A1 (de)
BR (1)	BRPI0509660A (de)
CA (1)	CA2561859A1 (de)
CR (1)	CR8696A (de)
DE (1)	DE602005020263D1 (de)
EA (1)	EA010546B1 (de)
EC (1)	ECSP066986A (de)
IL (1)	IL178435A0 (de)
MA (1)	MA28567B1 (de)
MX (1)	MXPA06011545A (de)
NO (1)	NO20064894L (de)
RS (1)	RS20060584A (de)
TN (1)	TNSN06321A1 (de)
TW (1)	TW200539880A (de)
UA (1)	UA88638C2 (de)
WO (1)	WO2005111037A1 (de)
ZA (1)	ZA200608956B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200630337A (en) *	2004-10-14	2006-09-01	Euro Celtique Sa	Piperidinyl compounds and the use thereof
WO2007110449A1 (en) *	2006-03-29	2007-10-04	Euro-Celtique S.A.	Benzenesulfonamide compounds and their use
TW200812963A (en) *	2006-04-13	2008-03-16	Euro Celtique Sa	Benzenesulfonamide compounds and the use thereof
WO2007118853A1 (en) *	2006-04-13	2007-10-25	Euro-Celtique S.A.	Benzenesulfonamide compounds and their use as blockers of calcium channels
US20100210633A1 (en) *	2006-10-12	2010-08-19	Epix Delaware, Inc.	Carboxamide compounds and their use
WO2008124118A1 (en)	2007-04-09	2008-10-16	Purdue Pharma L.P.	Benzenesulfonyl compounds and the use therof
WO2009040659A2 (en) *	2007-09-28	2009-04-02	Purdue Pharma L.P.	Benzenesulfonamide compounds and the use thereof
US20090131422A1 (en) *	2007-10-23	2009-05-21	Millennium Pharmaceuticals, Inc.	Salts of an IKK inhibitor
WO2009054970A1 (en) *	2007-10-23	2009-04-30	Millennium Pharmaceuticals, Inc.	Mesylate salt of an ikk inhibitor
AU2008335135A1 (en)	2007-12-11	2009-06-18	Cytopathfinder, Inc.	Carboxamide compounds and their use as chemokine receptor agonists
PL2592081T3 (pl)	2010-07-06	2017-07-31	Ono Pharmaceutical Co., Ltd.	Pochodna tetrahydrokarboliny
US9353113B2 (en)	2011-03-18	2016-05-31	Ono Pharmaceutical Co., Ltd.	Tetrahydrocarboline derivative
CN102416014B (zh) *	2011-09-13	2012-11-21	河南中医学院	一种生物碱类成分组合物在制备抗甲型h1n1流感病毒药物中的应用
CN108271369A (zh)	2015-10-23	2018-07-10	法尔玛赞公司	用于制备色胺及其衍生物的新工艺
CA3016729A1 (en)	2016-03-03	2017-09-08	Bill Elliot Cham	Glycoalkaloid combinations and various uses thereof
US11117893B2 (en) *	2018-09-24	2021-09-14	Union University	Methods for preparation of substituted pyridines and related novel compounds
WO2022223022A1 (zh) *	2021-04-23	2022-10-27	四川海思科制药有限公司	一种并环杂环衍生物及其在医药上的应用
CN120846792A (zh) *	2025-07-18	2025-10-28	苏州市环境监测站(苏州市环境监控中心)	一种水中微囊藻毒素的提取与检测方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000009492A1 (en)	1998-08-12	2000-02-24	Pfizer Products Inc.	Tace inhibitors
DE19951360A1 (de)	1999-10-26	2001-05-03	Aventis Pharma Gmbh	Substituierte Indole
EP1268477B1 (de) *	2000-03-15	2010-04-21	Sanofi-Aventis Deutschland GmbH	Substituierte beta-carboline mit ikb-kinase hemmender wirkung
CA2402549A1 (en)	2000-03-15	2001-09-20	Aventis Pharma Deutschland Gmbh	Substituted beta-carbolines
CA2460939C (en)	2001-09-19	2008-07-29	Pharmacia Corporation	Substituted pyrazolyl compounds for the treatment of inflammation
DE60217532T8 (de)	2001-11-07	2008-02-07	Millennium Pharmaceuticals, Inc., Cambridge	Carboline derivate als ikb-inhibitoren zur behandlung des m ultiplen myelomas
KR20060006031A (ko) *	2003-04-09	2006-01-18	밀레니엄 파머슈티컬스 인코퍼레이티드	염증 질환 치료에 유용한 베타-카르볼린

2005
- 2005-04-08 EP EP10003450A patent/EP2206713A1/de not_active Withdrawn
- 2005-04-08 CN CNA2005800190147A patent/CN1976931A/zh active Pending
- 2005-04-08 UA UAA200611756A patent/UA88638C2/ru unknown
- 2005-04-08 BR BRPI0509660-0A patent/BRPI0509660A/pt not_active IP Right Cessation
- 2005-04-08 EP EP05779267A patent/EP1735311B1/de not_active Expired - Lifetime
- 2005-04-08 MX MXPA06011545A patent/MXPA06011545A/es not_active Application Discontinuation
- 2005-04-08 AU AU2005243188A patent/AU2005243188A1/en not_active Withdrawn
- 2005-04-08 KR KR1020067023401A patent/KR20070014166A/ko not_active Ceased
- 2005-04-08 TW TW094111190A patent/TW200539880A/zh unknown
- 2005-04-08 US US11/101,998 patent/US7951801B2/en not_active Expired - Lifetime
- 2005-04-08 AT AT05779267T patent/ATE462702T1/de not_active IP Right Cessation
- 2005-04-08 JP JP2007507578A patent/JP2007532582A/ja active Pending
- 2005-04-08 WO PCT/US2005/013812 patent/WO2005111037A1/en not_active Ceased
- 2005-04-08 EA EA200601884A patent/EA010546B1/ru not_active IP Right Cessation
- 2005-04-08 CA CA002561859A patent/CA2561859A1/en not_active Abandoned
- 2005-04-08 RS RSP-2006/0584A patent/RS20060584A/sr unknown
- 2005-04-08 DE DE602005020263T patent/DE602005020263D1/de not_active Expired - Fee Related
2006
- 2006-10-04 IL IL178435A patent/IL178435A0/en unknown
- 2006-10-06 TN TNP2006000321A patent/TNSN06321A1/en unknown
- 2006-10-19 CR CR8696A patent/CR8696A/es unknown
- 2006-10-26 NO NO20064894A patent/NO20064894L/no not_active Application Discontinuation
- 2006-10-27 ZA ZA200608956A patent/ZA200608956B/en unknown
- 2006-11-02 MA MA29431A patent/MA28567B1/fr unknown
- 2006-11-09 EC EC2006006986A patent/ECSP066986A/es unknown

Also Published As

Publication number	Publication date
EA200601884A1 (ru)	2007-04-27
KR20070014166A (ko)	2007-01-31
EP2206713A1 (de)	2010-07-14
NO20064894L (no)	2007-01-03
EP1735311B1 (de)	2010-03-31
TNSN06321A1 (en)	2008-02-22
WO2005111037A1 (en)	2005-11-24
EP1735311A1 (de)	2006-12-27
EA010546B1 (ru)	2008-10-30
CN1976931A (zh)	2007-06-06
CR8696A (es)	2007-08-28
JP2007532582A (ja)	2007-11-15
ZA200608956B (en)	2008-06-25
US7951801B2 (en)	2011-05-31
MXPA06011545A (es)	2007-03-26
DE602005020263D1 (de)	2010-05-12
ECSP066986A (es)	2006-12-29
MA28567B1 (fr)	2007-05-02
AU2005243188A1 (en)	2005-11-24
US20050239781A1 (en)	2005-10-27
RS20060584A (sr)	2008-08-07
TW200539880A (en)	2005-12-16
IL178435A0 (en)	2007-02-11
UA88638C2 (ru)	2009-11-10
BRPI0509660A (pt)	2007-10-09
CA2561859A1 (en)	2005-11-24

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Publication	Publication Date	Title
ATE544748T1 (de)	2012-02-15	Zusammensetzungen und verfahren für die behandlung von zellproliferationserkrankungen
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DE602006018057D1 (de)	2010-12-16	Substituierte chinolone und verwendungsverfahren
EA200900802A1 (ru)	2010-04-30	Способы и композиции для лечения амилоидных заболеваний
EA200501771A1 (ru)	2006-06-30	Лиганды каннабиноидных рецепторов и их применения
DE602005015687D1 (de)	2009-09-10	Phospholipid-analoga für die behandlung von krebs
ATE433447T1 (de)	2009-06-15	Pyrimiidinverbindungen
EA200700175A1 (ru)	2007-08-31	Композиции и способы лечения воспалительных заболеваний
BRPI0514017A (pt)	2008-05-27	indazóis úteis no tratamento de doenças cardiovasculares
DE602006009968D1 (de)	2009-12-03	N4-phenyl-chinazolin-4-aminderivate und verwandte verbindungen als inhibitoren der erbb-typ-i-rezeptortyrosinkinase zur behandlung hyperproliferativer krankheiten
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ATE432930T1 (de)	2009-06-15	Benzosulfonamide derivate, deren verfahren zum herstellung, und deren verwendung zur behandlung von schmerzen
DE602004006118D1 (de)	2007-06-06	2,3,4,5-TETRAHYDROBENZOiFöi1,4öOXAZEPIN-5-CARBONSÄUREAMID DERIVATE ALS GAMMA-SECRETASE INHIBITOREN ZUR BEHANDLUNG VON ALZHEIMER
DE602004021363D1 (de)	2009-07-16	Imidazotriazin verbindungen zur behandlung von krebserkrankungen
DE602005015963D1 (de)	2009-09-24	Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen
ECSP066484A (es)	2006-10-10	Compuestos y metodos para el tratamiento de dislipidemia
NO20055563L (no)	2005-11-24	Midler for behandlingen av lavere abdominale lidelser
ATE410166T1 (de)	2008-10-15	4-phenyl-5-oxo-1,4,5,6,7,8-hexahydrochinolin- derivate zur behandlung von unfruchtbarkeit
ATE482217T1 (de)	2010-10-15	Dithiolopyrrolon-derivate zur behandlung von proliferativen störungen
DE602006016413D1 (de)	2010-10-07	Kim-1-antikörper zur behandlung von th2-vermittelten erkrankungen
NO20053562L (no)	2005-07-20	Nye aminobenzofenonforbindelser