|
US6677347B2
(en)
*
|
2000-12-08 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamido ether substituted imidazoquinolines
|
|
US8703146B2
(en)
|
2001-04-20 |
2014-04-22 |
Institute For Systems Biology |
Toll-like receptor 5 ligands and methods of use
|
|
WO2002085933A1
(en)
|
2001-04-20 |
2002-10-31 |
The Institute For Systems Biology |
Toll-like receptor 5 ligands and methods of use
|
|
US9045727B2
(en)
*
|
2002-05-17 |
2015-06-02 |
Emory University |
Virus-like particles, methods of preparation, and immunogenic compositions
|
|
EP1536832A2
(de)
*
|
2002-09-03 |
2005-06-08 |
Fondation Eurovacc |
Flagellin peptide als adjuvantien für impfstoffe
|
|
EP1599726A4
(de)
*
|
2003-02-27 |
2009-07-22 |
3M Innovative Properties Co |
Selektive modulation von tlr-vermittelter biologischer aktivität
|
|
WO2004094671A2
(en)
*
|
2003-04-22 |
2004-11-04 |
Coley Pharmaceutical Gmbh |
Methods and products for identification and assessment of tlr ligands
|
|
WO2004096144A2
(en)
*
|
2003-04-28 |
2004-11-11 |
3M Innovative Properties Company |
Compositions and methods for induction of opioid receptors
|
|
WO2005018556A2
(en)
*
|
2003-08-12 |
2005-03-03 |
3M Innovative Properties Company |
Hydroxylamine substituted imidazo-containing compounds
|
|
RU2006105101A
(ru)
*
|
2003-08-27 |
2007-10-10 |
3М Инновейтив Пропертиз Компани (US) |
Арилокси и арилалкиленокси замещенные имидазохинолины
|
|
WO2005023190A2
(en)
*
|
2003-09-05 |
2005-03-17 |
3M Innovative Properties Company |
Treatment for cd5+ b cell lymphoma
|
|
US8871782B2
(en)
*
|
2003-10-03 |
2014-10-28 |
3M Innovative Properties Company |
Alkoxy substituted imidazoquinolines
|
|
US20090075980A1
(en)
*
|
2003-10-03 |
2009-03-19 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridines and Analogs Thereof
|
|
US7544697B2
(en)
*
|
2003-10-03 |
2009-06-09 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridines and analogs thereof
|
|
WO2005040208A2
(en)
*
|
2003-10-21 |
2005-05-06 |
Androclus Therapeutics, Soa |
Peptides derived from heat shock proteins binding toll-like receptors 2 and 4 and their use
|
|
JP4966661B2
(ja)
*
|
2003-10-22 |
2012-07-04 |
アイディー バイオメディカル コーポレイション オブ ケベック |
生得的免疫およびアレルギー性免疫を活性化させるための組成物および方法
|
|
US8598192B2
(en)
*
|
2003-11-14 |
2013-12-03 |
3M Innovative Properties Company |
Hydroxylamine substituted imidazoquinolines
|
|
CA2545774A1
(en)
|
2003-11-14 |
2005-06-02 |
3M Innovative Properties Company |
Oxime substituted imidazo ring compounds
|
|
AR046781A1
(es)
*
|
2003-11-25 |
2005-12-21 |
3M Innovative Properties Co |
Derivados de imidazoquinolinas. composiciones farmaceuticas.
|
|
WO2005066170A1
(en)
*
|
2003-12-29 |
2005-07-21 |
3M Innovative Properties Company |
Arylalkenyl and arylalkynyl substituted imidazoquinolines
|
|
CA2551399A1
(en)
*
|
2003-12-30 |
2005-07-21 |
3M Innovative Properties Company |
Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
|
|
KR20050073865A
(ko)
*
|
2004-01-12 |
2005-07-18 |
대한민국(전남대학교총장) |
비브리오 패혈증균 편모 구성인자 플라젤린을유효성분으로 함유하는 백신 보조제
|
|
AU2005228150A1
(en)
*
|
2004-03-24 |
2005-10-13 |
3M Innovative Properties Company |
Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
|
|
WO2005107381A2
(en)
*
|
2004-05-07 |
2005-11-17 |
Hans-Gustaf Ljunggren |
Use of flagellin as an adjuvant for vaccine
|
|
DE102004024674A1
(de)
*
|
2004-05-18 |
2005-12-15 |
Wolfgang Lorenz |
Mittel und Verfahren zur Diagnose, Prophylaxe und Therapie von Bindegewebserkrankungen
|
|
WO2005123080A2
(en)
*
|
2004-06-15 |
2005-12-29 |
3M Innovative Properties Company |
Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
|
|
WO2006038923A2
(en)
*
|
2004-06-18 |
2006-04-13 |
3M Innovative Properties Company |
Aryl substituted imidazonaphthyridines
|
|
US8026366B2
(en)
*
|
2004-06-18 |
2011-09-27 |
3M Innovative Properties Company |
Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
|
|
WO2006065280A2
(en)
*
|
2004-06-18 |
2006-06-22 |
3M Innovative Properties Company |
Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
|
|
WO2006009832A1
(en)
*
|
2004-06-18 |
2006-01-26 |
3M Innovative Properties Company |
Substituted imidazo ring systems and methods
|
|
WO2006005004A2
(en)
*
|
2004-06-30 |
2006-01-12 |
University Of Florida Research Foundation Inc. |
Materials and methods for enhancing nitrogen fixation in plants
|
|
US20090270443A1
(en)
*
|
2004-09-02 |
2009-10-29 |
Doris Stoermer |
1-amino imidazo-containing compounds and methods
|
|
WO2006039701A1
(en)
*
|
2004-10-01 |
2006-04-13 |
University Of South Florida |
Flagellin-based adjuvants and vaccines
|
|
EP1819364A4
(de)
*
|
2004-12-08 |
2010-12-29 |
3M Innovative Properties Co |
Immunmodulatorische zusammensetzungen, kombinationen und verfahren
|
|
WO2006081007A2
(en)
*
|
2004-12-16 |
2006-08-03 |
Wake Forest University Health Sciences |
Use of flagellin in tumor immunotherapy
|
|
JP5285278B2
(ja)
|
2004-12-22 |
2013-09-11 |
クリーブランド クリニック ファウンデイション |
フラゲリン関連ポリペプチドおよびその使用
|
|
HU227285B1
(en)
*
|
2004-12-29 |
2011-01-28 |
Mta Enzimologiai Intezet |
Modified flagellins and flagellar filaments useful as receptors and processes for producing same
|
|
EP1831226B1
(de)
*
|
2004-12-30 |
2012-08-08 |
3M Innovative Properties Company |
Chirale tetracyklische verbindungen, die interferon biosyntheze induzieren
|
|
AU2005326708C1
(en)
|
2004-12-30 |
2012-08-30 |
3M Innovative Properties Company |
Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
|
|
AR052195A1
(es)
*
|
2005-01-19 |
2007-03-07 |
Vaxinnate Corp |
Composiciones de patrones moleculares asociados a patogenos en metodos de uso
|
|
AU2006210392A1
(en)
*
|
2005-02-04 |
2006-08-10 |
Coley Pharmaceutical Group, Inc. |
Aqueous gel formulations containing immune response modifiers
|
|
WO2006085411A1
(ja)
*
|
2005-02-10 |
2006-08-17 |
National University Corporation Hokkaido University |
免疫応答を惹起するための新規アジュバントおよびその利用
|
|
CA2597587A1
(en)
|
2005-02-11 |
2006-08-17 |
Coley Pharmaceutical Group, Inc. |
Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
|
|
US7700728B2
(en)
*
|
2005-03-24 |
2010-04-20 |
Schering Corporation |
Use of chimeric receptors in a screening assay for identifying agonists and antagonists of cell receptors
|
|
US7943636B2
(en)
|
2005-04-01 |
2011-05-17 |
3M Innovative Properties Company |
1-substituted pyrazolo (3,4-C) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
|
|
WO2006107853A2
(en)
|
2005-04-01 |
2006-10-12 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridine-1,4-diamines and analogs thereof
|
|
DE102005020798A1
(de)
*
|
2005-04-28 |
2006-11-02 |
Eberhard-Karls-Universität Tübingen Universitätsklinikum |
Verwendung von TLR- und/oder Nod2-Liganden zur Herstellung eines Arzneimittels zur Behandlung einer Krankheit des zentralen Nervensystems
|
|
KR100804507B1
(ko)
|
2005-05-17 |
2008-02-20 |
전남대학교산학협력단 |
플라젤린을 포함하는 천식 및 알레르기 질환 면역치료제
|
|
US8137930B2
(en)
*
|
2005-10-28 |
2012-03-20 |
University Of Maryland, Baltimore |
Attenuated Salmonella enterica serovar paratyphi A and uses thereof
|
|
WO2007062043A1
(en)
*
|
2005-11-23 |
2007-05-31 |
Coley Pharmaceutical Group Inc. |
Method of activating murine toll-like receptor 8
|
|
WO2007098371A2
(en)
*
|
2006-02-16 |
2007-08-30 |
Wayne State University |
Use of flagellin to prevent and treat gram negative bacterial infection
|
|
ES2555544T3
(es)
|
2006-03-07 |
2016-01-04 |
Vaxinnate Corporation |
Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas
|
|
US7906506B2
(en)
*
|
2006-07-12 |
2011-03-15 |
3M Innovative Properties Company |
Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
|
|
US20100159486A1
(en)
*
|
2006-11-01 |
2010-06-24 |
George Mason Intellectual Properties, Inc. |
Biomarkers for neurological conditions
|
|
EP2121734B1
(de)
*
|
2007-02-09 |
2013-05-08 |
Industry Foundation of Chonam National University |
Modifiziertes flagellin mit verbesserter stimulierung des toll-like-rezeptors 5
|
|
US20100330190A1
(en)
*
|
2007-12-17 |
2010-12-30 |
Compans Richard W |
Immunogenic compositions and methods of use thereof
|
|
WO2009082440A2
(en)
*
|
2007-12-18 |
2009-07-02 |
Vaxinnate Corporation |
Compositions of toll-like receptor agonists and malaria antigens and methods of use
|
|
SG190562A1
(en)
|
2008-04-18 |
2013-06-28 |
Vaxinnate Corp |
Deletion mutants of flagellin and methods of use
|
|
JP5577337B2
(ja)
|
2008-08-01 |
2014-08-20 |
クリーブランド バイオラブス, インコーポレイテッド |
再灌流傷害を治療するための方法
|
|
CA2739454C
(en)
*
|
2008-10-03 |
2018-05-01 |
Emory University |
Methods for the treatment of graft-versus-host disease
|
|
WO2010080007A2
(ko)
*
|
2009-01-09 |
2010-07-15 |
부산대학교 산학협력단 |
Toll 유사수용체2 리간드로서 기능하는 그람양성균 유래의 리포단백질
|
|
EP2408475B1
(de)
|
2009-03-18 |
2017-11-15 |
Wake Forest University Health Sciences |
Flagellin-fusionsproteine und ihre verwendung zur auslösung von immunantworten gegen pseudomonas aeruginosa
|
|
WO2010135704A2
(en)
*
|
2009-05-22 |
2010-11-25 |
Institute For Systems Biology |
Secretion-related bacterial proteins for nlrc4 stimulation
|
|
US20120135037A1
(en)
|
2009-06-01 |
2012-05-31 |
Mizel Steven B |
Flagellin fusion proteins and conjugates comprising pneumococcus antigens and methods of using the same
|
|
US20120171239A1
(en)
|
2009-09-03 |
2012-07-05 |
Mizel Steven B |
Immunogenic Conjugates for Producing Immune Responses to Drugs of Abuse and Methods of Use
|
|
US20130108661A1
(en)
|
2010-02-05 |
2013-05-02 |
Mount Sinai School Of Medicine |
Methods and compositions for cancer immunotherapy using flagellin-tumor associated antigen fusion protein expressing tumor cells
|
|
GB2481267B
(en)
*
|
2010-06-15 |
2016-04-20 |
Univ Leicester |
Assay for determining the risk of a toll-like receptor containing foodstuff for causing systemic inflammation in vivo
|
|
KR101768118B1
(ko)
|
2010-06-25 |
2017-08-14 |
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) |
기도 감염의 치료를 위한 방법 및 약학 조성물
|
|
US9872895B2
(en)
|
2010-09-24 |
2018-01-23 |
Emory University |
TLR5 ligands, therapeutic methods, and compositions related thereto
|
|
EP2663367A4
(de)
|
2011-01-10 |
2014-08-06 |
Cleveland Biolabs Inc |
Verwendung von toll-ähnlichen rezeptoragonisten zur behandlung von krebs
|
|
GB201112091D0
(en)
|
2011-07-14 |
2011-08-31 |
Gt Biolog Ltd |
Bacterial strains isolated from pigs
|
|
GB201117313D0
(en)
|
2011-10-07 |
2011-11-16 |
Gt Biolog Ltd |
Bacterium for use in medicine
|
|
EP2847215A1
(de)
*
|
2012-05-07 |
2015-03-18 |
Synthes GmbH |
Verfahren und vorrichtungen zur behandlung einer bandscheibenerkrankung
|
|
US9296792B2
(en)
|
2012-05-23 |
2016-03-29 |
The Board Of Trustees Of The Leland Stanford Junior University |
Ordered flagellin array as an immunostimulant
|
|
US8932598B2
(en)
|
2012-08-28 |
2015-01-13 |
Vaxinnate Corporation |
Fusion proteins and methods of use
|
|
GB201306536D0
(en)
|
2013-04-10 |
2013-05-22 |
Gt Biolog Ltd |
Polypeptide and immune modulation
|
|
EP3024476A1
(de)
|
2013-07-26 |
2016-06-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Verbindungen und pharmazeutische zusammensetzungen zur behandlung von bakterieninfektionen
|
|
EP3174893B1
(de)
|
2014-07-30 |
2020-05-06 |
Genome Protection, Inc. |
Flagellinzusammensetzungen und verwendungen
|
|
WO2016109002A2
(en)
|
2014-10-16 |
2016-07-07 |
Cleveland Biolabs, Inc. |
Methods and compositions for the treatment of radiation-related disorders
|
|
PE20171138A1
(es)
|
2014-12-23 |
2017-08-09 |
4D Pharma Res Ltd |
Modulacion inmunitaria
|
|
DK3193901T3
(en)
|
2014-12-23 |
2018-05-28 |
4D Pharma Res Ltd |
PIRIN POLYPEPTIDE AND IMMUNMODULATION
|
|
US10676723B2
(en)
|
2015-05-11 |
2020-06-09 |
David Gordon Bermudes |
Chimeric protein toxins for expression by therapeutic bacteria
|
|
PE20180243A1
(es)
|
2015-06-15 |
2018-01-31 |
4D Pharma Res Ltd |
Composiciones que comprenden cepas bacterianas
|
|
MA41010B1
(fr)
|
2015-06-15 |
2020-01-31 |
4D Pharma Res Ltd |
Compositions comprenant des souches bactériennes
|
|
MA41060B1
(fr)
|
2015-06-15 |
2019-11-29 |
4D Pharma Res Ltd |
Compositions comprenant des souches bactériennes
|
|
EP3662917A1
(de)
|
2015-06-15 |
2020-06-10 |
4D Pharma Research Limited |
Zusammensetzungen mit bakterienstämmen
|
|
LT3360559T
(lt)
|
2015-06-15 |
2019-12-27 |
4D Pharma Research Limited |
Kompozicijos, apimančios bakterijų kamienus
|
|
GB201520497D0
(en)
|
2015-11-20 |
2016-01-06 |
4D Pharma Res Ltd |
Compositions comprising bacterial strains
|
|
MA41013A
(fr)
|
2015-11-20 |
2017-08-30 |
4D Pharma Res Ltd |
Compositions comprenant des souches bactériennes
|
|
GB201520631D0
(en)
|
2015-11-23 |
2016-01-06 |
4D Pharma Res Ltd |
Compositions comprising bacterial strains
|
|
GB201520638D0
(en)
|
2015-11-23 |
2016-01-06 |
4D Pharma Res Ltd |
Compositions comprising bacterial strains
|
|
MX373290B
(es)
|
2016-03-04 |
2020-06-18 |
4D Pharma Plc |
Composiciones que comprenden cepas bacterianas.
|
|
GB201612191D0
(en)
|
2016-07-13 |
2016-08-24 |
4D Pharma Plc |
Compositions comprising bacterial strains
|
|
TWI802545B
(zh)
|
2016-07-13 |
2023-05-21 |
英商4D製藥有限公司 |
包含細菌菌株之組合物
|
|
GB201621123D0
(en)
|
2016-12-12 |
2017-01-25 |
4D Pharma Plc |
Compositions comprising bacterial strains
|
|
MA48940A
(fr)
|
2017-05-22 |
2020-04-08 |
4D Pharma Res Ltd |
Compositions comprenant des souches bactériennes
|
|
MA41708A
(fr)
|
2017-05-24 |
2020-04-08 |
4D Pharma Res Ltd |
Compositions comprenant des souches bactériennes
|
|
JP2020523326A
(ja)
|
2017-06-14 |
2020-08-06 |
フォーディー ファーマ リサーチ リミテッド4D Pharma Research Limited |
細菌株を含む組成物
|
|
TWI767013B
(zh)
|
2017-06-14 |
2022-06-11 |
英商4D製藥研究有限公司 |
包含細菌品系之組成物
|
|
PL3638271T3
(pl)
|
2017-06-14 |
2021-03-22 |
4D Pharma Research Limited |
Kompozycje zawierające szczepy bakteryjne
|
|
JP7722629B2
(ja)
*
|
2017-07-04 |
2025-08-13 |
キュアバック エスイー |
新規核酸分子
|
|
US10717767B2
(en)
|
2017-07-20 |
2020-07-21 |
Spogen Biotech, Inc. |
Bioactive polypeptides for improvements in plant protection, growth and productivity
|
|
US12440536B2
(en)
|
2018-05-18 |
2025-10-14 |
The University Of Hong Kong |
Compositions of toll-like receptor 5 (TLR5) agonist and methods of use thereof
|
|
KR102524577B1
(ko)
*
|
2019-04-22 |
2023-04-21 |
전남대학교산학협력단 |
플라젤린 융합 단백질 및 이의 용도
|
|
FR3114970B1
(fr)
|
2020-10-08 |
2023-06-30 |
Univ Tours |
Combinaison d’anticorps inhalés avec des agents immunomodulateurs pour le traitement ou la prévention d’inféctions respiratoires
|
|
KR102461645B1
(ko)
*
|
2020-10-20 |
2022-11-01 |
전남대학교산학협력단 |
플라젤린 융합 단백질을 포함하는 비알코올성 지방간질환 또는 대사증후군 예방 또는 치료용 조성물
|
|
US20240277801A1
(en)
|
2021-06-30 |
2024-08-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Aerosol composition for pulmonary delivery of flagellin
|
|
WO2024035137A1
(ko)
*
|
2022-08-10 |
2024-02-15 |
주식회사 메디스팬 |
바실러스 서브틸리스 플라젤린 변이체 및 이의 용도
|
|
KR102896818B1
(ko)
*
|
2022-10-19 |
2025-12-08 |
전남대학교 산학협력단 |
Tlr5 활성능을 가진 플라젤린 면역증강제 유도체의 진핵세포 발현시스템을 이용한 제조 및 응용
|
|
WO2025172452A1
(en)
|
2024-02-14 |
2025-08-21 |
Institut National de la Santé et de la Recherche Médicale |
Combination for treating bacterial infection due to pseudomonas aeruginosa antibiotic-resistant strain
|
|
WO2026022365A1
(en)
*
|
2024-07-26 |
2026-01-29 |
Elanco Animal Health Gmbh |
Mammalian il-4/il-13/flagellin constructs
|