ATE466020T1 - Neue isoform des gefässendothelzell wachstumshemmers (vegi) - Google Patents

Neue isoform des gefässendothelzell wachstumshemmers (vegi)

Info

Publication number
ATE466020T1
ATE466020T1 AT02793986T AT02793986T ATE466020T1 AT E466020 T1 ATE466020 T1 AT E466020T1 AT 02793986 T AT02793986 T AT 02793986T AT 02793986 T AT02793986 T AT 02793986T AT E466020 T1 ATE466020 T1 AT E466020T1
Authority
AT
Austria
Prior art keywords
vegi
isoforms
vascular
cell growth
growth inhibitor
Prior art date
Application number
AT02793986T
Other languages
English (en)
Inventor
Luyuan Li
Hongguang Pan
Original Assignee
Univ Georgetown
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgetown filed Critical Univ Georgetown
Application granted granted Critical
Publication of ATE466020T1 publication Critical patent/ATE466020T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02793986T 2001-11-09 2002-11-12 Neue isoform des gefässendothelzell wachstumshemmers (vegi) ATE466020T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33119001P 2001-11-09 2001-11-09
PCT/US2002/037426 WO2003039491A2 (en) 2001-11-09 2002-11-12 Novel isoforms of vascular endothelial cell growth inhibitor

Publications (1)

Publication Number Publication Date
ATE466020T1 true ATE466020T1 (de) 2010-05-15

Family

ID=23292954

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02793986T ATE466020T1 (de) 2001-11-09 2002-11-12 Neue isoform des gefässendothelzell wachstumshemmers (vegi)

Country Status (10)

Country Link
US (2) US7498407B2 (de)
EP (1) EP1487854B1 (de)
CN (1) CN100398551C (de)
AT (1) ATE466020T1 (de)
AU (1) AU2002359446B2 (de)
CA (1) CA2465953A1 (de)
DE (1) DE60236212D1 (de)
ES (1) ES2345329T3 (de)
RU (1) RU2316591C2 (de)
WO (1) WO2003039491A2 (de)

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WO2003039491A2 (en) 2001-11-09 2003-05-15 Georgetown University Novel isoforms of vascular endothelial cell growth inhibitor
CN1311076C (zh) * 2003-04-16 2007-04-18 普罗特奥姆技术公司 生产重组尿激酶的方法
WO2005058930A2 (en) * 2003-12-11 2005-06-30 Proteomtech Inc. Methods for production of recombinant vascular endothelial cell growth inhibitor
WO2005058243A2 (en) * 2003-12-11 2005-06-30 Proteomtech Inc. Methods for treating cancer using vascular endothelial cell growth inhibitor vegi-192a
AU2006284922B2 (en) 2005-08-30 2012-01-19 University Of Miami Immunomodulating tumor necrosis factor receptor 25 (TNFR25) agonists, antagonists and immunotoxins
US20070218535A1 (en) * 2005-11-28 2007-09-20 Xinli Lin Methods for production of recombinant alpha1-antitrypsin
UA104132C2 (en) 2007-11-13 2014-01-10 Тева Биофармасьютикалз Юесей, Инк. Humanized antibodies against tl1a
CN101503474B (zh) * 2009-03-09 2012-07-04 中山大学 一种人血管内皮细胞生长抑制因子嵌合多肽及其制备方法和在靶向性抗肿瘤活性中的应用
CN101503697B (zh) * 2009-03-09 2013-08-07 中山大学 一种人血管内皮细胞生长抑制因子rhVEGI-192A的重组蛋白的制备方法
SG10201502330TA (en) 2009-08-03 2015-05-28 Univ Miami Method for in vivo expansion of t regulatory cells
CN102453097A (zh) * 2010-10-27 2012-05-16 上海科新生物技术股份有限公司 抑制血管新生的融合蛋白vf及药物组合物和应用
US20140193410A1 (en) 2013-01-09 2014-07-10 University Of Miami Compositions and Methods for the Regulation of T Regulatory Cells Using TL1A-Ig Fusion Protein
US10398369B2 (en) 2014-08-08 2019-09-03 Medtronic Xomed, Inc. Wireless stimulation probe device for wireless nerve integrity monitoring systems
CN107951862B (zh) * 2016-10-17 2021-03-12 南京绿叶制药有限公司 一种抑制bcl-2的反义寡聚核酸的脂质纳米粒及其制备方法
CN111569051B (zh) * 2020-05-11 2021-10-22 中山大学 人血管内皮细胞抑制因子vegi-251在制备抗肿瘤药物中的应用
CN121843714A (zh) 2023-08-11 2026-04-10 派拉冈医疗公司 Tl1a结合抗体及使用方法

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Also Published As

Publication number Publication date
US7498407B2 (en) 2009-03-03
EP1487854A2 (de) 2004-12-22
RU2316591C2 (ru) 2008-02-10
WO2003039491A2 (en) 2003-05-15
US20030170242A1 (en) 2003-09-11
CA2465953A1 (en) 2003-05-15
EP1487854B1 (de) 2010-04-28
CN100398551C (zh) 2008-07-02
US7750133B2 (en) 2010-07-06
AU2002359446B2 (en) 2008-12-04
ES2345329T3 (es) 2010-09-21
RU2004117536A (ru) 2005-04-20
CN1668630A (zh) 2005-09-14
DE60236212D1 (de) 2010-06-10
WO2003039491A3 (en) 2004-09-30
WO2003039491A8 (en) 2003-10-30
US20090227014A1 (en) 2009-09-10
EP1487854A4 (de) 2006-01-04

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