ATE466868T1 - Zusammensetzungen und verfahren zur trennung von fusionsproteinen - Google Patents

Zusammensetzungen und verfahren zur trennung von fusionsproteinen

Info

Publication number
ATE466868T1
ATE466868T1 AT06779979T AT06779979T ATE466868T1 AT E466868 T1 ATE466868 T1 AT E466868T1 AT 06779979 T AT06779979 T AT 06779979T AT 06779979 T AT06779979 T AT 06779979T AT E466868 T1 ATE466868 T1 AT E466868T1
Authority
AT
Austria
Prior art keywords
compositions
methods
fusion proteins
separating fusion
separating
Prior art date
Application number
AT06779979T
Other languages
English (en)
Inventor
Sujeong Kim
Jong-Mook Kim
Song Shan Xu
Original Assignee
Viromed Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viromed Co Ltd filed Critical Viromed Co Ltd
Application granted granted Critical
Publication of ATE466868T1 publication Critical patent/ATE466868T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5431—IL-11
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57581—Thymosin; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Endocrinology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
AT06779979T 2005-04-20 2006-04-20 Zusammensetzungen und verfahren zur trennung von fusionsproteinen ATE466868T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67287905P 2005-04-20 2005-04-20
PCT/IB2006/002378 WO2006126102A2 (en) 2005-04-20 2006-04-20 Compositions and methods for fusion protein separation

Publications (1)

Publication Number Publication Date
ATE466868T1 true ATE466868T1 (de) 2010-05-15

Family

ID=37452418

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06779979T ATE466868T1 (de) 2005-04-20 2006-04-20 Zusammensetzungen und verfahren zur trennung von fusionsproteinen

Country Status (8)

Country Link
US (2) US7585943B2 (de)
EP (1) EP1871785B1 (de)
JP (1) JP4897792B2 (de)
KR (1) KR101312339B1 (de)
CN (1) CN101287748B (de)
AT (1) ATE466868T1 (de)
DE (1) DE602006014126D1 (de)
WO (1) WO2006126102A2 (de)

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WO2011151716A1 (en) 2010-06-04 2011-12-08 Lupin Limited Process for the purification of recombinant human il-11
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EP2600891B1 (de) 2010-08-05 2018-01-17 Council of Scientific & Industrial Research Proteinfusionskonstrukte mit thrombolyse- und gerinnungshemmenden eigenschaften
CN102161700A (zh) * 2011-01-19 2011-08-24 温州医学院 一种新型人白细胞介素-11
CA3080181A1 (en) * 2011-03-04 2012-09-13 Shire Human Genetic Therapies, Inc. Peptide linkers for polypeptide compositions and methods for using same
US8580922B2 (en) 2011-03-04 2013-11-12 Shire Human Genetic Therapies, Inc. Peptide linkers for polypeptide compositions and methods for using same
KR20140036905A (ko) * 2012-09-18 2014-03-26 삼성전자주식회사 이중특이 항체를 포함하는 단백질 복합체
WO2014084432A1 (ko) * 2012-11-30 2014-06-05 경상대학교 산학협력단 헬리코박터 파일로리 발현 벡터
WO2014197816A1 (en) * 2013-06-06 2014-12-11 Massachusetts Institute Of Technology Stimulus responsive nanocomplexes and methods of use thereof
JP6046862B2 (ja) * 2013-08-21 2016-12-21 カディラ ヘルスケア リミテッド Ｐｔｈの精製方法
KR101814048B1 (ko) 2014-01-28 2018-01-02 (주)에이피테크놀로지 대량 생산이 가능하도록 개선된 경구투여용 트롬보포이에틴 및 이의 대량 생산공정
WO2016089782A1 (en) 2014-12-01 2016-06-09 Pfenex Inc. Fusion partners for peptide production
CN104437411A (zh) * 2014-12-15 2015-03-25 武汉大学 可逆组装和分解的Strep-tag多肽标记的生物分子衍生化基质及其应用
CN106884030A (zh) * 2015-12-16 2017-06-23 丰益(上海)生物技术研发中心有限公司 提高含纤维素结合域的融合蛋白的发酵产量的方法
JP6758889B2 (ja) * 2016-04-07 2020-09-23 シスメックス株式会社 標的タンパク質の精製方法
WO2020113403A1 (en) * 2018-12-04 2020-06-11 Beijing Percans Oncology Co. Ltd. Cytokine fusion proteins
CN112105632A (zh) 2018-01-24 2020-12-18 北京智康博药肿瘤医学研究有限公司 细胞因子融合蛋白
KR102140531B1 (ko) * 2018-08-07 2020-08-04 (주)휴온스 Gly-Tβ4의 제조방법
US20220214340A1 (en) * 2019-04-28 2022-07-07 Leide Biosciences Co., Ltd. Zipper structure that helps the formation of protein dimer and application thereof
CN110484551B (zh) * 2019-07-29 2021-04-02 因之彩生物科技（武汉）有限公司 金属硫蛋白表达载体及其应用
MX2022004711A (es) * 2019-10-22 2022-06-14 Icahn School Med Mount Sinai Neuraminidasa recombinante y usos de la misma.
CN111909947B (zh) * 2020-08-04 2022-06-07 辽宁省海洋水产科学研究院 一种仿刺参β-胸腺素的制备及应用
CN112946041B (zh) * 2021-02-06 2022-07-22 自然资源部第一海洋研究所 一种基于融合蛋白传感器的重金属离子检测方法
CN115078728B (zh) * 2021-03-11 2024-10-22 盛禾(中国)生物制药有限公司 一种融合蛋白的快速分析方法
CN114644715B (zh) * 2022-03-04 2024-08-20 苏州红冠庄国药股份有限公司 一种igfbp-3和igf-1的融合蛋白及复合物制备方法
CN118638209A (zh) * 2024-06-20 2024-09-13 上海唯科生物制药有限公司 一种重组肿瘤坏死因子的生产方法

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Also Published As

Publication number Publication date
HK1125387A1 (en) 2009-08-07
DE602006014126D1 (de) 2010-06-17
CN101287748A (zh) 2008-10-15
CN101287748B (zh) 2013-03-27
US20080171852A9 (en) 2008-07-17
US20060276625A1 (en) 2006-12-07
JP4897792B2 (ja) 2012-03-14
US7585943B2 (en) 2009-09-08
EP1871785A4 (de) 2009-03-18
EP1871785A2 (de) 2008-01-02
KR101312339B1 (ko) 2013-09-27
US8106158B2 (en) 2012-01-31
US20100285526A1 (en) 2010-11-11
KR20080002845A (ko) 2008-01-04
WO2006126102A8 (en) 2008-05-15
JP2008539696A (ja) 2008-11-20
WO2006126102A2 (en) 2006-11-30
EP1871785B1 (de) 2010-05-05

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