ATE466883T1 - Katalytische monoklonale antikörper mit proteaseaktivität zur selektiven lysis der proteinkomponente von mit pathologischen konditionen zusammenhängenden plaques und aggregaten - Google Patents

Katalytische monoklonale antikörper mit proteaseaktivität zur selektiven lysis der proteinkomponente von mit pathologischen konditionen zusammenhängenden plaques und aggregaten

Info

Publication number
ATE466883T1
ATE466883T1 AT98945101T AT98945101T ATE466883T1 AT E466883 T1 ATE466883 T1 AT E466883T1 AT 98945101 T AT98945101 T AT 98945101T AT 98945101 T AT98945101 T AT 98945101T AT E466883 T1 ATE466883 T1 AT E466883T1
Authority
AT
Austria
Prior art keywords
plaques
monoclonal antibodies
protease activity
protein component
pathological conditions
Prior art date
Application number
AT98945101T
Other languages
English (en)
Inventor
Silvia Trasciatti
Sergio Rosini
Original Assignee
Abiogen Pharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abiogen Pharma Spa filed Critical Abiogen Pharma Spa
Application granted granted Critical
Publication of ATE466883T1 publication Critical patent/ATE466883T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0002—Antibodies with enzymatic activity, e.g. abzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT98945101T 1997-07-30 1998-07-28 Katalytische monoklonale antikörper mit proteaseaktivität zur selektiven lysis der proteinkomponente von mit pathologischen konditionen zusammenhängenden plaques und aggregaten ATE466883T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97MI001826A IT1293511B1 (it) 1997-07-30 1997-07-30 Anticorpi monoclonali catalitici ad attivita' proteasica per la lisi selettiva della componente proteica di placche e aggregati correlati
PCT/EP1998/004706 WO1999006066A2 (en) 1997-07-30 1998-07-28 Catalytic monoclonal antibodies with protease activity for the selective lysis of the protein component of plaques and aggregates related to pathological conditions

Publications (1)

Publication Number Publication Date
ATE466883T1 true ATE466883T1 (de) 2010-05-15

Family

ID=11377678

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98945101T ATE466883T1 (de) 1997-07-30 1998-07-28 Katalytische monoklonale antikörper mit proteaseaktivität zur selektiven lysis der proteinkomponente von mit pathologischen konditionen zusammenhängenden plaques und aggregaten

Country Status (17)

Country Link
US (1) US6387674B1 (de)
EP (1) EP0996463B1 (de)
JP (1) JP2001511369A (de)
CN (1) CN1268175A (de)
AT (1) ATE466883T1 (de)
AU (1) AU741368B2 (de)
CA (1) CA2299442C (de)
CY (1) CY1110128T1 (de)
DE (1) DE69841653D1 (de)
DK (1) DK0996463T3 (de)
ES (1) ES2340892T3 (de)
IL (1) IL134142A0 (de)
IT (1) IT1293511B1 (de)
NO (1) NO329769B1 (de)
NZ (1) NZ502527A (de)
PT (1) PT996463E (de)
WO (1) WO1999006066A2 (de)

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US20030147882A1 (en) 1998-05-21 2003-08-07 Alan Solomon Methods for amyloid removal using anti-amyloid antibodies
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Also Published As

Publication number Publication date
WO1999006066A3 (en) 1999-04-29
NO329769B1 (no) 2010-12-13
DE69841653D1 (de) 2010-06-17
ITMI971826A1 (it) 1999-01-30
NO20000396L (no) 2000-03-29
EP0996463B1 (de) 2010-05-05
EP0996463A2 (de) 2000-05-03
DK0996463T3 (da) 2010-08-09
US6387674B1 (en) 2002-05-14
JP2001511369A (ja) 2001-08-14
IL134142A0 (en) 2001-04-30
PT996463E (pt) 2010-05-17
AU741368B2 (en) 2001-11-29
ES2340892T3 (es) 2010-06-10
AU9255398A (en) 1999-02-22
NO20000396D0 (no) 2000-01-26
IT1293511B1 (it) 1999-03-01
CY1110128T1 (el) 2015-01-14
NZ502527A (en) 2003-01-31
CN1268175A (zh) 2000-09-27
CA2299442A1 (en) 1999-02-11
CA2299442C (en) 2011-06-21
WO1999006066A2 (en) 1999-02-11

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