ATE469911T1 - Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung - Google Patents
Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendungInfo
- Publication number
- ATE469911T1 ATE469911T1 AT99953231T AT99953231T ATE469911T1 AT E469911 T1 ATE469911 T1 AT E469911T1 AT 99953231 T AT99953231 T AT 99953231T AT 99953231 T AT99953231 T AT 99953231T AT E469911 T1 ATE469911 T1 AT E469911T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- acid molecules
- tif
- applications
- isolated nucleic
- Prior art date
Links
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 230000001939 inductive effect Effects 0.000 title abstract 2
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 102000000585 Interleukin-9 Human genes 0.000 abstract 1
- 108010002335 Interleukin-9 Proteins 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 229940118526 interleukin-9 Drugs 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/178,973 US6274710B1 (en) | 1998-10-26 | 1998-10-26 | Antibodies which specifically bind T Cell inducible factors (TIFs) |
| US09/354,243 US6359117B1 (en) | 1998-10-26 | 1999-07-16 | Isolated nucleic acid molecules which encode T cell inducible factors (TIFs), the proteins encoded, and uses therefor |
| PCT/US1999/024424 WO2000024758A1 (en) | 1998-10-26 | 1999-10-18 | ISOLATED NUCLEIC ACID MOLECULES WHICH ENCODE T CELL INDUCIBLE FACTORS (TIFs), THE PROTEINS ENCODED, AND USES THEREOF |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE469911T1 true ATE469911T1 (de) | 2010-06-15 |
Family
ID=22654680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99953231T ATE469911T1 (de) | 1998-10-26 | 1999-10-18 | Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US6274710B1 (de) |
| CN (1) | CN1789411A (de) |
| AT (1) | ATE469911T1 (de) |
| DE (1) | DE69942459D1 (de) |
| ES (1) | ES2346831T3 (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965704A (en) * | 1997-08-05 | 1999-10-12 | Zymogenetics, Inc. | Class two cytokine receptor-11 |
| US6551799B2 (en) * | 1999-12-07 | 2003-04-22 | Genentech, Inc. | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
| US7081528B2 (en) * | 1998-10-26 | 2006-07-25 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules encoding T cell derived inducible factors |
| US6274710B1 (en) * | 1998-10-26 | 2001-08-14 | Ludwig Institute For Cancer Research | Antibodies which specifically bind T Cell inducible factors (TIFs) |
| JP4828703B2 (ja) * | 1999-04-28 | 2011-11-30 | ジェネティックス インスティテュート エルエルシー | ヒトgil−19/ae289タンパク質、及び、同タンパク質をコードするポリヌクレオチド |
| US7307161B1 (en) | 1999-04-28 | 2007-12-11 | Genetics Institute, Llc | Human Gil-19/AE289 polynucleotides |
| US6939545B2 (en) * | 1999-04-28 | 2005-09-06 | Genetics Institute, Llc | Composition and method for treating inflammatory disorders |
| WO2001040467A1 (en) * | 1999-12-03 | 2001-06-07 | Zymogenetics, Inc. | Human cytokine receptor |
| US7226591B2 (en) * | 2000-05-22 | 2007-06-05 | Genentech, Inc. | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
| US20030170823A1 (en) * | 1999-12-23 | 2003-09-11 | Presnell Scott R. | Novel cytokine ZCYTO18 |
| US20030012788A1 (en) * | 2000-07-27 | 2003-01-16 | Jean-Christophe Renauld | Method for influencing kinase pathways with IL-22 |
| ATE342980T1 (de) * | 2000-08-08 | 2006-11-15 | Zymogenetics Inc | Lösliche zcyctor 11 cytokinrezeptoren |
| US7638604B2 (en) * | 2001-02-23 | 2009-12-29 | Genetics Institute, Llc | Monoclonal antibodies against interleukin-22 |
| JP2005503765A (ja) * | 2001-03-27 | 2005-02-10 | ザイモジェネティクス,インコーポレイティド | ヒトサイトカイン受容体 |
| CA2480163A1 (en) * | 2002-03-22 | 2003-10-09 | Zymogenetics, Inc. | Anti-il-tif antibodies and methods of using in inflammation |
| DE602004028347D1 (de) * | 2003-03-24 | 2010-09-09 | Zymogenetics Inc | Anti-il-22ra antikörper und bindungspartner und verwendungsmethoden bei entzündung |
| EA015706B1 (ru) | 2004-10-22 | 2011-10-31 | Займоджинетикс, Инк. | Моноклональное антитело или его фрагмент, связывающиеся с полипептидом il-22ra, гуманизированное антитело, полученное из указанного антитела, гибридомы, продуцирующие антитело, и применение указанного антитела |
| CN100515491C (zh) * | 2005-01-04 | 2009-07-22 | 健能隆医药技术(上海)有限公司 | 白介素-22的医药用途 |
| AU2006212807A1 (en) * | 2005-02-08 | 2006-08-17 | Zymogenetics, Inc. | Anti-IL-20, anti-IL-22 and anti-IL-22RA antibodies and binding partners and methods of using in inflammation |
| EP2623516B1 (de) * | 2005-12-02 | 2015-07-15 | Genentech, Inc. | Zusammensetzungen und Verfahren für die Behandlung von Krankheiten und Störungen in Zusammenhang mit der Zytokinsignalisierung, mit Antikörper, die an IL-22 und IL-22R bind. |
| TWI417301B (zh) | 2006-02-21 | 2013-12-01 | Wyeth Corp | 對抗人類介白素-22(il-22)之抗體及其用途 |
| TW200744634A (en) * | 2006-02-21 | 2007-12-16 | Wyeth Corp | Methods of using antibodies against human IL-22 |
| CN101361968B (zh) | 2007-08-06 | 2011-08-03 | 健能隆医药技术(上海)有限公司 | 白介素-22在治疗脂肪肝中的应用 |
| CN102260343A (zh) | 2010-05-25 | 2011-11-30 | 健能隆医药技术(上海)有限公司 | 重组人g-csf二聚体在治疗神经损伤疾病中的用途 |
| CN102380091A (zh) | 2010-08-31 | 2012-03-21 | 健能隆医药技术(上海)有限公司 | 白介素-22在治疗病毒性肝炎中的应用 |
| AU2012289433B2 (en) | 2011-07-25 | 2017-07-27 | Evive Biotechnology (Shanghai) Ltd | Use of G-CSF dimer in preparation of medicament for treatment of neurodegenerative diseases |
| CN103182072B (zh) | 2011-12-27 | 2017-05-03 | 健能隆医药技术(上海)有限公司 | 白介素‑22在治疗和预防神经损伤疾病或神经退行性疾病中的用途 |
| WO2014053481A1 (en) | 2012-10-03 | 2014-04-10 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the prophylactic treatment of bacterial superinfections post-influenza |
| CN104623639A (zh) | 2013-11-07 | 2015-05-20 | 健能隆医药技术(上海)有限公司 | 白介素22二聚体在制备治疗胰腺炎药物中的应用 |
| CN104623637A (zh) | 2013-11-07 | 2015-05-20 | 健能隆医药技术(上海)有限公司 | Il-22二聚体在制备静脉注射药物中的应用 |
| WO2015070077A1 (en) | 2013-11-07 | 2015-05-14 | Memorial Sloan-Kettering Cancer Center | Methods of use for il-22 in the treatment of gastrointestinal graft vs. host disease |
| EP3167892A1 (de) | 2015-11-10 | 2017-05-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Verfahren und pharmazeutische zusammensetzungen zur vorbeugung oder behandlung von entzündlichen darmerkrankungen |
| US11510966B2 (en) | 2016-04-15 | 2022-11-29 | Evive Biotechnology (Shanghai) Ltd | Use of IL-22 in treating necrotizing enterocolitis |
| EP3802596A4 (de) | 2018-06-05 | 2022-07-20 | BioAtla, Inc. | Anti-il-22-antikörper, antikörperfragmente, deren immunkonjugate und verwendungen davon |
| US12527875B2 (en) | 2020-02-19 | 2026-01-20 | Evive Biotechnology (Shanghai) Ltd | Methods for treating graft versus host disease |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002516103A (ja) * | 1998-05-29 | 2002-06-04 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | インターロイキン21およびインターロイキン22 |
| US6274710B1 (en) * | 1998-10-26 | 2001-08-14 | Ludwig Institute For Cancer Research | Antibodies which specifically bind T Cell inducible factors (TIFs) |
| US6331613B1 (en) * | 1998-10-26 | 2001-12-18 | Ludwig Institue For Cancer Research | Isolated nucleic acid molecules which encode T cell inducible factors (TIFS), the proteins encoded, and uses thereof |
| US7081528B2 (en) * | 1998-10-26 | 2006-07-25 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules encoding T cell derived inducible factors |
| JP4828703B2 (ja) * | 1999-04-28 | 2011-11-30 | ジェネティックス インスティテュート エルエルシー | ヒトgil−19/ae289タンパク質、及び、同タンパク質をコードするポリヌクレオチド |
| US6939545B2 (en) * | 1999-04-28 | 2005-09-06 | Genetics Institute, Llc | Composition and method for treating inflammatory disorders |
| US7307161B1 (en) * | 1999-04-28 | 2007-12-11 | Genetics Institute, Llc | Human Gil-19/AE289 polynucleotides |
| WO2000073457A1 (en) | 1999-05-27 | 2000-12-07 | Schering-Corporation | Mammalian interleukin-10 homologs: il-d110 and il-d210 |
| US20030012788A1 (en) * | 2000-07-27 | 2003-01-16 | Jean-Christophe Renauld | Method for influencing kinase pathways with IL-22 |
-
1998
- 1998-10-26 US US09/178,973 patent/US6274710B1/en not_active Expired - Fee Related
-
1999
- 1999-07-16 US US09/354,243 patent/US6359117B1/en not_active Expired - Fee Related
- 1999-10-18 DE DE69942459T patent/DE69942459D1/de not_active Expired - Lifetime
- 1999-10-18 AT AT99953231T patent/ATE469911T1/de not_active IP Right Cessation
- 1999-10-18 ES ES99953231T patent/ES2346831T3/es not_active Expired - Lifetime
- 1999-10-18 CN CNA2005101169982A patent/CN1789411A/zh active Pending
-
2007
- 2007-09-21 US US11/902,473 patent/US7972833B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1789411A (zh) | 2006-06-21 |
| DE69942459D1 (de) | 2010-07-15 |
| US7972833B2 (en) | 2011-07-05 |
| ES2346831T3 (es) | 2010-10-20 |
| US6359117B1 (en) | 2002-03-19 |
| US6274710B1 (en) | 2001-08-14 |
| US20080213881A1 (en) | 2008-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |