|
US2264423A
(en)
*
|
1939-08-29 |
1941-12-02 |
Roy L Wingenroth |
Blast furnace receiving hopper
|
|
US3687808A
(en)
*
|
1969-08-14 |
1972-08-29 |
Univ Leland Stanford Junior |
Synthetic polynucleotides
|
|
US4469863A
(en)
*
|
1980-11-12 |
1984-09-04 |
Ts O Paul O P |
Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
|
|
US4711955A
(en)
*
|
1981-04-17 |
1987-12-08 |
Yale University |
Modified nucleotides and methods of preparing and using same
|
|
CA1190838A
(en)
|
1981-07-17 |
1985-07-23 |
Cavit Akin |
Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer
|
|
US5023243A
(en)
*
|
1981-10-23 |
1991-06-11 |
Molecular Biosystems, Inc. |
Oligonucleotide therapeutic agent and method of making same
|
|
US4476301A
(en)
*
|
1982-04-29 |
1984-10-09 |
Centre National De La Recherche Scientifique |
Oligonucleotides, a process for preparing the same and their application as mediators of the action of interferon
|
|
US4994373A
(en)
*
|
1983-01-27 |
1991-02-19 |
Enzo Biochem, Inc. |
Method and structures employing chemically-labelled polynucleotide probes
|
|
CA1228811A
(en)
|
1983-05-05 |
1987-11-03 |
Robert G. Pergolizzi |
Assay method utilizing polynucleotide sequences
|
|
US5118800A
(en)
*
|
1983-12-20 |
1992-06-02 |
California Institute Of Technology |
Oligonucleotides possessing a primary amino group in the terminal nucleotide
|
|
US4748111A
(en)
*
|
1984-03-12 |
1988-05-31 |
Molecular Diagnostics, Inc. |
Nucleic acid-protein conjugate used in immunoassay
|
|
US5550111A
(en)
*
|
1984-07-11 |
1996-08-27 |
Temple University-Of The Commonwealth System Of Higher Education |
Dual action 2',5'-oligoadenylate antiviral derivatives and uses thereof
|
|
FR2567892B1
(fr)
*
|
1984-07-19 |
1989-02-17 |
Centre Nat Rech Scient |
Nouveaux oligonucleotides, leur procede de preparation et leurs applications comme mediateurs dans le developpement des effets des interferons
|
|
US5367066A
(en)
*
|
1984-10-16 |
1994-11-22 |
Chiron Corporation |
Oligonucleotides with selectably cleavable and/or abasic sites
|
|
US5242794A
(en)
*
|
1984-12-13 |
1993-09-07 |
Applied Biosystems, Inc. |
Detection of specific sequences in nucleic acids
|
|
US4883750A
(en)
*
|
1984-12-13 |
1989-11-28 |
Applied Biosystems, Inc. |
Detection of specific sequences in nucleic acids
|
|
FR2575751B1
(fr)
*
|
1985-01-08 |
1987-04-03 |
Pasteur Institut |
Nouveaux nucleosides de derives de l'adenosine, leur preparation et leurs applications biologiques
|
|
US5235033A
(en)
*
|
1985-03-15 |
1993-08-10 |
Anti-Gene Development Group |
Alpha-morpholino ribonucleoside derivatives and polymers thereof
|
|
US5185444A
(en)
*
|
1985-03-15 |
1993-02-09 |
Anti-Gene Deveopment Group |
Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages
|
|
US5034506A
(en)
*
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
|
US5166315A
(en)
*
|
1989-12-20 |
1992-11-24 |
Anti-Gene Development Group |
Sequence-specific binding polymers for duplex nucleic acids
|
|
US5405938A
(en)
*
|
1989-12-20 |
1995-04-11 |
Anti-Gene Development Group |
Sequence-specific binding polymers for duplex nucleic acids
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US4965188A
(en)
*
|
1986-08-22 |
1990-10-23 |
Cetus Corporation |
Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
|
|
US5264423A
(en)
*
|
1987-03-25 |
1993-11-23 |
The United States Of America As Represented By The Department Of Health And Human Services |
Inhibitors for replication of retroviruses and for the expression of oncogene products
|
|
US5276019A
(en)
*
|
1987-03-25 |
1994-01-04 |
The United States Of America As Represented By The Department Of Health And Human Services |
Inhibitors for replication of retroviruses and for the expression of oncogene products
|
|
ATE113059T1
(de)
*
|
1987-06-24 |
1994-11-15 |
Florey Howard Inst |
Nukleosid-derivate.
|
|
US4924624A
(en)
*
|
1987-10-22 |
1990-05-15 |
Temple University-Of The Commonwealth System Of Higher Education |
2,',5'-phosphorothioate oligoadenylates and plant antiviral uses thereof
|
|
US5188897A
(en)
*
|
1987-10-22 |
1993-02-23 |
Temple University Of The Commonwealth System Of Higher Education |
Encapsulated 2',5'-phosphorothioate oligoadenylates
|
|
CA1340807C
(en)
*
|
1988-02-24 |
1999-11-02 |
Lawrence T. Malek |
Nucleic acid amplification process
|
|
WO1989009221A1
(en)
*
|
1988-03-25 |
1989-10-05 |
University Of Virginia Alumni Patents Foundation |
Oligonucleotide n-alkylphosphoramidates
|
|
US5278302A
(en)
*
|
1988-05-26 |
1994-01-11 |
University Patents, Inc. |
Polynucleotide phosphorodithioates
|
|
US5216141A
(en)
*
|
1988-06-06 |
1993-06-01 |
Benner Steven A |
Oligonucleotide analogs containing sulfur linkages
|
|
US5130238A
(en)
*
|
1988-06-24 |
1992-07-14 |
Cangene Corporation |
Enhanced nucleic acid amplification process
|
|
US5175273A
(en)
*
|
1988-07-01 |
1992-12-29 |
Genentech, Inc. |
Nucleic acid intercalating agents
|
|
GB8818020D0
(en)
|
1988-07-28 |
1988-09-01 |
Ici Plc |
Method for amplification of nucleotide sequences
|
|
US4984957A
(en)
*
|
1988-08-08 |
1991-01-15 |
Kubota, Ltd. |
Work-implement adapter for front loader
|
|
ATE142272T1
(de)
|
1989-01-19 |
1996-09-15 |
Behringwerke Ag |
Nukleinsäure-amplifikation unter verwendung eines einzelprimers
|
|
US5629158A
(en)
|
1989-03-22 |
1997-05-13 |
Cemu Bitecknik Ab |
Solid phase diagnosis of medical conditions
|
|
US5198543A
(en)
*
|
1989-03-24 |
1993-03-30 |
Consejo Superior Investigaciones Cientificas |
PHI29 DNA polymerase
|
|
US5001050A
(en)
*
|
1989-03-24 |
1991-03-19 |
Consejo Superior Investigaciones Cientificas |
PHφ29 DNA polymerase
|
|
US5106727A
(en)
|
1989-04-27 |
1992-04-21 |
Life Technologies, Inc. |
Amplification of nucleic acid sequences using oligonucleotides of random sequences as primers
|
|
US5043272A
(en)
*
|
1989-04-27 |
1991-08-27 |
Life Technologies, Incorporated |
Amplification of nucleic acid sequences using oligonucleotides of random sequence as primers
|
|
US5143854A
(en)
*
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
US5134066A
(en)
*
|
1989-08-29 |
1992-07-28 |
Monsanto Company |
Improved probes using nucleosides containing 3-dezauracil analogs
|
|
JP2581833B2
(ja)
*
|
1989-09-11 |
1997-02-12 |
株式会社日立製作所 |
プラントの運転状態監視システム
|
|
US5591722A
(en)
|
1989-09-15 |
1997-01-07 |
Southern Research Institute |
2'-deoxy-4'-thioribonucleosides and their antiviral activity
|
|
US5399676A
(en)
*
|
1989-10-23 |
1995-03-21 |
Gilead Sciences |
Oligonucleotides with inverted polarity
|
|
US5264564A
(en)
*
|
1989-10-24 |
1993-11-23 |
Gilead Sciences |
Oligonucleotide analogs with novel linkages
|
|
US5264562A
(en)
*
|
1989-10-24 |
1993-11-23 |
Gilead Sciences, Inc. |
Oligonucleotide analogs with novel linkages
|
|
DK0942000T3
(da)
*
|
1989-10-24 |
2004-11-01 |
Isis Pharmaceuticals Inc |
2'-modificerede oligonukleotider
|
|
US5177198A
(en)
*
|
1989-11-30 |
1993-01-05 |
University Of N.C. At Chapel Hill |
Process for preparing oligoribonucleoside and oligodeoxyribonucleoside boranophosphates
|
|
US5130302A
(en)
*
|
1989-12-20 |
1992-07-14 |
Boron Bilogicals, Inc. |
Boronated nucleoside, nucleotide and oligonucleotide compounds, compositions and methods for using same
|
|
US5681941A
(en)
|
1990-01-11 |
1997-10-28 |
Isis Pharmaceuticals, Inc. |
Substituted purines and oligonucleotide cross-linking
|
|
US5459255A
(en)
|
1990-01-11 |
1995-10-17 |
Isis Pharmaceuticals, Inc. |
N-2 substituted purines
|
|
US5646265A
(en)
|
1990-01-11 |
1997-07-08 |
Isis Pharmceuticals, Inc. |
Process for the preparation of 2'-O-alkyl purine phosphoramidites
|
|
US5670633A
(en)
|
1990-01-11 |
1997-09-23 |
Isis Pharmaceuticals, Inc. |
Sugar modified oligonucleotides that detect and modulate gene expression
|
|
US5587361A
(en)
*
|
1991-10-15 |
1996-12-24 |
Isis Pharmaceuticals, Inc. |
Oligonucleotides having phosphorothioate linkages of high chiral purity
|
|
ES2089038T3
(es)
|
1990-01-26 |
1996-10-01 |
Abbott Lab |
Procedimiento mejorado para amplificar acidos nucleicos blanco aplicable para la reaccion en cadena de polimerasa y ligasa.
|
|
US5427930A
(en)
*
|
1990-01-26 |
1995-06-27 |
Abbott Laboratories |
Amplification of target nucleic acids using gap filling ligase chain reaction
|
|
US5321131A
(en)
*
|
1990-03-08 |
1994-06-14 |
Hybridon, Inc. |
Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling
|
|
US5470967A
(en)
*
|
1990-04-10 |
1995-11-28 |
The Dupont Merck Pharmaceutical Company |
Oligonucleotide analogs with sulfamate linkages
|
|
GB9009980D0
(en)
*
|
1990-05-03 |
1990-06-27 |
Amersham Int Plc |
Phosphoramidite derivatives,their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides
|
|
ES2116977T3
(es)
*
|
1990-05-11 |
1998-08-01 |
Microprobe Corp |
Soportes solidos para ensayos de hibridacion de acidos nucleicos y metodos para inmovilizar oligonucleotidos de modo covalente.
|
|
JPH06500014A
(ja)
|
1990-07-25 |
1994-01-06 |
シンジーン,インコーポレイテッド |
多数の核酸相補体を生成させる環状伸長法
|
|
US5677437A
(en)
|
1990-07-27 |
1997-10-14 |
Isis Pharmaceuticals, Inc. |
Heteroatomic oligonucleoside linkages
|
|
US5618704A
(en)
|
1990-07-27 |
1997-04-08 |
Isis Pharmacueticals, Inc. |
Backbone-modified oligonucleotide analogs and preparation thereof through radical coupling
|
|
JPH0874B2
(ja)
|
1990-07-27 |
1996-01-10 |
アイシス・ファーマシューティカルス・インコーポレーテッド |
遺伝子発現を検出および変調するヌクレアーゼ耐性、ピリミジン修飾オリゴヌクレオチド
|
|
US5541307A
(en)
*
|
1990-07-27 |
1996-07-30 |
Isis Pharmaceuticals, Inc. |
Backbone modified oligonucleotide analogs and solid phase synthesis thereof
|
|
US5608046A
(en)
|
1990-07-27 |
1997-03-04 |
Isis Pharmaceuticals, Inc. |
Conjugated 4'-desmethyl nucleoside analog compounds
|
|
US5623070A
(en)
|
1990-07-27 |
1997-04-22 |
Isis Pharmaceuticals, Inc. |
Heteroatomic oligonucleoside linkages
|
|
US5610289A
(en)
|
1990-07-27 |
1997-03-11 |
Isis Pharmaceuticals, Inc. |
Backbone modified oligonucleotide analogues
|
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
|
US5489677A
(en)
*
|
1990-07-27 |
1996-02-06 |
Isis Pharmaceuticals, Inc. |
Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms
|
|
ATE131827T1
(de)
|
1990-08-03 |
1996-01-15 |
Sterling Winthrop Inc |
Verbindungen und verfahren zur unterdrückung der genexpression
|
|
US5177196A
(en)
*
|
1990-08-16 |
1993-01-05 |
Microprobe Corporation |
Oligo (α-arabinofuranosyl nucleotides) and α-arabinofuranosyl precursors thereof
|
|
US5214134A
(en)
*
|
1990-09-12 |
1993-05-25 |
Sterling Winthrop Inc. |
Process of linking nucleosides with a siloxane bridge
|
|
US5561225A
(en)
*
|
1990-09-19 |
1996-10-01 |
Southern Research Institute |
Polynucleotide analogs containing sulfonate and sulfonamide internucleoside linkages
|
|
EP0549686A4
(en)
|
1990-09-20 |
1995-01-18 |
Gilead Sciences Inc |
Modified internucleoside linkages
|
|
US5432272A
(en)
*
|
1990-10-09 |
1995-07-11 |
Benner; Steven A. |
Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases
|
|
US5264567A
(en)
*
|
1990-10-22 |
1993-11-23 |
Mect Corporation |
GM3 analogous compound
|
|
US5455166A
(en)
*
|
1991-01-31 |
1995-10-03 |
Becton, Dickinson And Company |
Strand displacement amplification
|
|
US5489667A
(en)
|
1991-03-20 |
1996-02-06 |
Atochem Deutschland Gmbh |
Polyetheresteramides and process for making and using the same
|
|
US5539082A
(en)
*
|
1993-04-26 |
1996-07-23 |
Nielsen; Peter E. |
Peptide nucleic acids
|
|
US5719262A
(en)
|
1993-11-22 |
1998-02-17 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having amino acid side chains
|
|
US5714331A
(en)
|
1991-05-24 |
1998-02-03 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
|
|
US5571799A
(en)
*
|
1991-08-12 |
1996-11-05 |
Basco, Ltd. |
(2'-5') oligoadenylate analogues useful as inhibitors of host-v5.-graft response
|
|
US5273638A
(en)
*
|
1991-09-30 |
1993-12-28 |
Beckman Instruments, Inc. |
Nucleotide sequence determination employing matched dideoxynucleotide terminator concentrations
|
|
ES2103918T3
(es)
*
|
1991-10-17 |
1997-10-01 |
Ciba Geigy Ag |
Nucleosidos biciclicos, oligonucleotidos, procedimiento para su obtencion y productos intermedios.
|
|
US5594121A
(en)
|
1991-11-07 |
1997-01-14 |
Gilead Sciences, Inc. |
Enhanced triple-helix and double-helix formation with oligomers containing modified purines
|
|
US5412087A
(en)
*
|
1992-04-24 |
1995-05-02 |
Affymax Technologies N.V. |
Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces
|
|
US5484908A
(en)
*
|
1991-11-26 |
1996-01-16 |
Gilead Sciences, Inc. |
Oligonucleotides containing 5-propynyl pyrimidines
|
|
US5359044A
(en)
*
|
1991-12-13 |
1994-10-25 |
Isis Pharmaceuticals |
Cyclobutyl oligonucleotide surrogates
|
|
FR2687679B1
(fr)
|
1992-02-05 |
1994-10-28 |
Centre Nat Rech Scient |
Oligothionucleotides.
|
|
US5633360A
(en)
|
1992-04-14 |
1997-05-27 |
Gilead Sciences, Inc. |
Oligonucleotide analogs capable of passive cell membrane permeation
|
|
DE4216120A1
(de)
*
|
1992-05-15 |
1993-11-18 |
Bayer Ag |
å-Phthalocyanine
|
|
US5434257A
(en)
*
|
1992-06-01 |
1995-07-18 |
Gilead Sciences, Inc. |
Binding compentent oligomers containing unsaturated 3',5' and 2',5' linkages
|
|
EP0577558A2
(de)
|
1992-07-01 |
1994-01-05 |
Ciba-Geigy Ag |
Carbocyclische Nukleoside mit bicyclischen Ringen, Oligonukleotide daraus, Verfahren zu deren Herstellung, deren Verwendung und Zwischenproduckte
|
|
US5547843A
(en)
*
|
1992-07-17 |
1996-08-20 |
Associated Universities, Inc. |
Method for promoting specific alignment of short oligonucleotides on nucleic acids
|
|
WO1994003624A1
(en)
|
1992-08-04 |
1994-02-17 |
Auerbach Jeffrey I |
Methods for the isothermal amplification of nucleic acid molecules
|
|
US5614389A
(en)
|
1992-08-04 |
1997-03-25 |
Replicon, Inc. |
Methods for the isothermal amplification of nucleic acid molecules
|
|
US5733733A
(en)
|
1992-08-04 |
1998-03-31 |
Replicon, Inc. |
Methods for the isothermal amplification of nucleic acid molecules
|
|
JP3778925B2
(ja)
|
1993-01-15 |
2006-05-24 |
ザ パブリック ヘルス リサーチ インスティチュート オブ ザ シティー オブ ニューヨーク インク |
高感度核酸サンドイッチハイブリダイゼーション検定法及びキット
|
|
US5476925A
(en)
*
|
1993-02-01 |
1995-12-19 |
Northwestern University |
Oligodeoxyribonucleotides including 3'-aminonucleoside-phosphoramidate linkages and terminal 3'-amino groups
|
|
GB9304618D0
(en)
*
|
1993-03-06 |
1993-04-21 |
Ciba Geigy Ag |
Chemical compounds
|
|
AU6449394A
(en)
*
|
1993-03-30 |
1994-10-24 |
Sterling Winthrop Inc. |
Acyclic nucleoside analogs and oligonucleotide sequences containing them
|
|
CA2159629A1
(en)
|
1993-03-31 |
1994-10-13 |
Sanofi |
Oligonucleotides with amide linkages replacing phosphodiester linkages
|
|
DE4311944A1
(de)
|
1993-04-10 |
1994-10-13 |
Degussa |
Umhüllte Natriumpercarbonatpartikel, Verfahren zu deren Herstellung und sie enthaltende Wasch-, Reinigungs- und Bleichmittelzusammensetzungen
|
|
US6096880A
(en)
*
|
1993-04-15 |
2000-08-01 |
University Of Rochester |
Circular DNA vectors for synthesis of RNA and DNA
|
|
US5714320A
(en)
|
1993-04-15 |
1998-02-03 |
University Of Rochester |
Rolling circle synthesis of oligonucleotides and amplification of select randomized circular oligonucleotides
|
|
US5462854A
(en)
|
1993-04-19 |
1995-10-31 |
Beckman Instruments, Inc. |
Inverse linkage oligonucleotides for chemical and enzymatic processes
|
|
EP0710296A4
(de)
|
1993-07-23 |
1999-05-26 |
Bio Rad Laboratories |
Lineare vervielfältigung von nukleinsäuren
|
|
AU689789B2
(en)
|
1993-07-23 |
1998-04-09 |
Gen-Probe Incorporated |
Methods for enhancing nucleic acid amplification
|
|
US6294664B1
(en)
|
1993-07-29 |
2001-09-25 |
Isis Pharmaceuticals, Inc. |
Synthesis of oligonucleotides
|
|
US5322687A
(en)
|
1993-07-29 |
1994-06-21 |
Ecogen Inc. |
Bacillus thuringiensis cryet4 and cryet5 toxin genes and proteins toxic to lepidopteran insects
|
|
US5502177A
(en)
*
|
1993-09-17 |
1996-03-26 |
Gilead Sciences, Inc. |
Pyrimidine derivatives for labeled binding partners
|
|
JP3334279B2
(ja)
*
|
1993-09-30 |
2002-10-15 |
カシオ計算機株式会社 |
ピッチ表示装置
|
|
US5429807A
(en)
*
|
1993-10-28 |
1995-07-04 |
Beckman Instruments, Inc. |
Method and apparatus for creating biopolymer arrays on a solid support surface
|
|
US5925517A
(en)
|
1993-11-12 |
1999-07-20 |
The Public Health Research Institute Of The City Of New York, Inc. |
Detectably labeled dual conformation oligonucleotide probes, assays and kits
|
|
US5457187A
(en)
*
|
1993-12-08 |
1995-10-10 |
Board Of Regents University Of Nebraska |
Oligonucleotides containing 5-fluorouracil
|
|
US5446137B1
(en)
*
|
1993-12-09 |
1998-10-06 |
Behringwerke Ag |
Oligonucleotides containing 4'-substituted nucleotides
|
|
US5519134A
(en)
*
|
1994-01-11 |
1996-05-21 |
Isis Pharmaceuticals, Inc. |
Pyrrolidine-containing monomers and oligomers
|
|
CA2140081C
(en)
|
1994-01-13 |
2008-04-01 |
Dean L. Engelhardt |
Process, construct and conjugate for producing multiple nucleic acid copies
|
|
SE9400522D0
(sv)
|
1994-02-16 |
1994-02-16 |
Ulf Landegren |
Method and reagent for detecting specific nucleotide sequences
|
|
US5834252A
(en)
|
1995-04-18 |
1998-11-10 |
Glaxo Group Limited |
End-complementary polymerase reaction
|
|
KR100230718B1
(ko)
|
1994-03-16 |
1999-11-15 |
다니엘 엘. 캐시앙, 헨리 엘. 노르호프 |
등온 가닥 변위 핵산 증폭법
|
|
US5596091A
(en)
|
1994-03-18 |
1997-01-21 |
The Regents Of The University Of California |
Antisense oligonucleotides comprising 5-aminoalkyl pyrimidine nucleotides
|
|
US5627053A
(en)
|
1994-03-29 |
1997-05-06 |
Ribozyme Pharmaceuticals, Inc. |
2'deoxy-2'-alkylnucleotide containing nucleic acid
|
|
US5625050A
(en)
|
1994-03-31 |
1997-04-29 |
Amgen Inc. |
Modified oligonucleotides and intermediates useful in nucleic acid therapeutics
|
|
US5547861A
(en)
|
1994-04-18 |
1996-08-20 |
Becton, Dickinson And Company |
Detection of nucleic acid amplification
|
|
CA2148140C
(en)
*
|
1994-04-29 |
2010-08-10 |
John W. Sutherland |
Homogeneous method for assay of double-stranded nucleic acids using fluorescent dyes and kit useful therein
|
|
US5525711A
(en)
*
|
1994-05-18 |
1996-06-11 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Pteridine nucleotide analogs as fluorescent DNA probes
|
|
US5942391A
(en)
|
1994-06-22 |
1999-08-24 |
Mount Sinai School Of Medicine |
Nucleic acid amplification method: ramification-extension amplification method (RAM)
|
|
WO1995035390A1
(en)
|
1994-06-22 |
1995-12-28 |
Mount Sinai School Of Medicine Of The City University Of New York |
Ligation-dependent amplification for the detection of infectious pathogens and abnormal genes
|
|
US5876924A
(en)
*
|
1994-06-22 |
1999-03-02 |
Mount Sinai School Of Medicine |
Nucleic acid amplification method hybridization signal amplification method (HSAM)
|
|
US5451203A
(en)
*
|
1994-07-29 |
1995-09-19 |
Orthopedic Systems, Inc. |
Traction mechanism
|
|
US5597909A
(en)
|
1994-08-25 |
1997-01-28 |
Chiron Corporation |
Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use
|
|
US5516134A
(en)
*
|
1994-09-20 |
1996-05-14 |
Perfect Season, Inc. |
Seat for a wheeled vehicle
|
|
US5451067A
(en)
*
|
1994-10-18 |
1995-09-19 |
Pieper; Julius A. |
Chuck key with integral holder
|
|
FR2726277B1
(fr)
|
1994-10-28 |
1996-12-27 |
Bio Merieux |
Oligonucleotide utilisable comme amorce dans une methode d'amplification basee sur une replication avec deplacement de brin
|
|
US5821084A
(en)
|
1994-11-21 |
1998-10-13 |
The Regents Of The University Of Michigan |
Osteoblast-testicular protein tyrosine phosphatase
|
|
US6281332B1
(en)
|
1994-12-02 |
2001-08-28 |
The Johns Hopkins University School Of Medicine |
Hedgehog-derived polypeptides
|
|
US5563912A
(en)
*
|
1995-02-27 |
1996-10-08 |
Nec Corporation |
High efficiency speech coding apparatus and transit switching system employing the same
|
|
US5629179A
(en)
|
1995-03-17 |
1997-05-13 |
Novagen, Inc. |
Method and kit for making CDNA library
|
|
DE69632870T2
(de)
|
1995-03-17 |
2005-07-14 |
John Wayne Cancer Institute, Santa Monica |
Nachweis von melanomenmetastasen unter verwendung eines mehrfachmarker-tests
|
|
US5648245A
(en)
*
|
1995-05-09 |
1997-07-15 |
Carnegie Institution Of Washington |
Method for constructing an oligonucleotide concatamer library by rolling circle replication
|
|
US5734058A
(en)
|
1995-11-09 |
1998-03-31 |
Biometric Imaging, Inc. |
Fluorescent DNA-Intercalating cyanine dyes including a positively charged benzothiazole substituent
|
|
US5658735A
(en)
|
1995-11-09 |
1997-08-19 |
Biometric Imaging, Inc. |
Cyclized fluorescent nucleic acid intercalating cyanine dyes and nucleic acid detection methods
|
|
US5854033A
(en)
|
1995-11-21 |
1998-12-29 |
Yale University |
Rolling circle replication reporter systems
|
|
WO1997019193A2
(en)
|
1995-11-21 |
1997-05-29 |
Yale University |
Unimolecular segment amplification and detection
|
|
ES2262902T3
(es)
|
1995-12-05 |
2006-12-01 |
Jorn Erland Koch |
Una reaccion en cascada de amplificacion de acido nucleico.
|
|
GB9609213D0
(en)
|
1996-05-02 |
1996-07-03 |
Tepnel Medical Ltd |
Amplification of nucleic acids
|
|
US5614390A
(en)
|
1996-06-14 |
1997-03-25 |
Becton, Dickinson And Company |
Species-specific detection of Mycobacterium kansasii
|
|
US6117635A
(en)
|
1996-07-16 |
2000-09-12 |
Intergen Company |
Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
|
|
US5866336A
(en)
*
|
1996-07-16 |
1999-02-02 |
Oncor, Inc. |
Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
|
|
SE9603171D0
(sv)
|
1996-08-30 |
1996-08-30 |
Marek Kwiatkowski |
Solid phase synthesis
|
|
CA2286864A1
(en)
|
1997-01-10 |
1998-07-16 |
Pioneer Hi-Bred International, Inc. |
Hybridization-based genetic amplification and analysis
|
|
US6297006B1
(en)
|
1997-01-16 |
2001-10-02 |
Hyseq, Inc. |
Methods for sequencing repetitive sequences and for determining the order of sequence subfragments
|
|
US6017703A
(en)
|
1997-03-06 |
2000-01-25 |
Bard Diagnostic Sciences, Inc. |
Methods and compositions for screening for or modulating a tumor associated antigen
|
|
KR19990004292A
(ko)
|
1997-06-27 |
1999-01-15 |
윤종용 |
항균 전자렌지
|
|
US6124120A
(en)
|
1997-10-08 |
2000-09-26 |
Yale University |
Multiple displacement amplification
|
|
US6054274A
(en)
|
1997-11-12 |
2000-04-25 |
Hewlett-Packard Company |
Method of amplifying the signal of target nucleic acid sequence analyte
|
|
AU3909199A
(en)
|
1997-12-15 |
1999-07-05 |
Nexstar Pharmaceuticals, Inc. |
Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
|
|
US6087102A
(en)
|
1998-01-07 |
2000-07-11 |
Clontech Laboratories, Inc. |
Polymeric arrays and methods for their use in binding assays
|
|
US6287776B1
(en)
|
1998-02-02 |
2001-09-11 |
Signature Bioscience, Inc. |
Method for detecting and classifying nucleic acid hybridization
|
|
JP3944996B2
(ja)
|
1998-03-05 |
2007-07-18 |
株式会社日立製作所 |
Dnaプローブアレー
|
|
US6312902B1
(en)
|
1998-03-13 |
2001-11-06 |
Promega Corporation |
Nucleic acid detection
|
|
US6031078A
(en)
|
1998-06-16 |
2000-02-29 |
Millennium Pharmaceuticals, Inc. |
MTbx protein and nucleic acid molecules and uses therefor
|
|
US6203984B1
(en)
*
|
1998-07-02 |
2001-03-20 |
Pacron, Inc. |
Proportional amplification of mRNA from a linear template in vitro
|
|
US6316229B1
(en)
|
1998-07-20 |
2001-11-13 |
Yale University |
Single molecule analysis target-mediated ligation of bipartite primers
|
|
US6180408B1
(en)
|
1998-08-21 |
2001-01-30 |
Washington University |
Fluorescence polarization in nucleic acid analysis
|
|
US6287824B1
(en)
|
1998-09-15 |
2001-09-11 |
Yale University |
Molecular cloning using rolling circle amplification
|
|
US6277607B1
(en)
|
1999-05-24 |
2001-08-21 |
Sanjay Tyagi |
High specificity primers, amplification methods and kits
|
|
US6274320B1
(en)
*
|
1999-09-16 |
2001-08-14 |
Curagen Corporation |
Method of sequencing a nucleic acid
|
|
JP2003515149A
(ja)
*
|
1999-11-26 |
2003-04-22 |
キュラジェン コーポレイション |
核酸プローブアレイ
|
|
US6458544B1
(en)
|
1999-12-02 |
2002-10-01 |
Dna Sciences, Inc. |
Methods for determining single nucleotide variations and genotyping
|
|
US6248535B1
(en)
|
1999-12-20 |
2001-06-19 |
University Of Southern California |
Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
|
|
US6221603B1
(en)
|
2000-02-04 |
2001-04-24 |
Molecular Dynamics, Inc. |
Rolling circle amplification assay for nucleic acid analysis
|
|
US6291187B1
(en)
|
2000-05-12 |
2001-09-18 |
Molecular Staging, Inc. |
Poly-primed amplification of nucleic acid sequences
|
|
US6323009B1
(en)
|
2000-06-28 |
2001-11-27 |
Molecular Staging, Inc. |
Multiply-primed amplification of nucleic acid sequences
|
|
US6479242B1
(en)
|
2000-10-26 |
2002-11-12 |
Cleveland State University |
Method for genotyping of single nucleotide polymorphism
|
|
US6573051B2
(en)
|
2001-03-09 |
2003-06-03 |
Molecular Staging, Inc. |
Open circle probes with intramolecular stem structures
|
|
US6479244B1
(en)
|
2001-04-23 |
2002-11-12 |
Galileo Genomics |
Method for genotyping microsatellite DNA markers
|
|
US6617137B2
(en)
|
2001-10-15 |
2003-09-09 |
Molecular Staging Inc. |
Method of amplifying whole genomes without subjecting the genome to denaturing conditions
|