ATE470669T1 - D-(17alpha)-13-ethyl-17hydroxy-18,19-dinorpregn 4-ene-20-yne-3-one in form des reinen 3e- und 3z- oximes sowie das verfahren zur herstellung der mischung der isomere wie auch der reinen isomere - Google Patents

D-(17alpha)-13-ethyl-17hydroxy-18,19-dinorpregn 4-ene-20-yne-3-one in form des reinen 3e- und 3z- oximes sowie das verfahren zur herstellung der mischung der isomere wie auch der reinen isomere

Info

Publication number
ATE470669T1
ATE470669T1 AT04730317T AT04730317T ATE470669T1 AT E470669 T1 ATE470669 T1 AT E470669T1 AT 04730317 T AT04730317 T AT 04730317T AT 04730317 T AT04730317 T AT 04730317T AT E470669 T1 ATE470669 T1 AT E470669T1
Authority
AT
Austria
Prior art keywords
pure
isomers
dinorpregn
17alpha
yne
Prior art date
Application number
AT04730317T
Other languages
English (en)
Inventor
Zoltan Tuba
Sandor Maho
Gyoergy Keseru
Jozsef Kozma
Janos Horvath
Gabor Balogh
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Application granted granted Critical
Publication of ATE470669T1 publication Critical patent/ATE470669T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Indole Compounds (AREA)
AT04730317T 2003-06-30 2004-04-29 D-(17alpha)-13-ethyl-17hydroxy-18,19-dinorpregn 4-ene-20-yne-3-one in form des reinen 3e- und 3z- oximes sowie das verfahren zur herstellung der mischung der isomere wie auch der reinen isomere ATE470669T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0301981A HUP0301981A2 (hu) 2003-06-30 2003-06-30 Tiszta d-(17alfa)-13-etil-17-hidroxi-18,19-dinor-pregn-4-én-20-in-3-on-3E- és 3Z-oxim izomerek, valamint eljárás az izomer keverékek és a tiszta izomerek előállítására
PCT/HU2004/000030 WO2005000867A1 (en) 2003-06-30 2004-04-29 PURE D-(17α)-13-ETHYL-17-HYDROXY-18,19-DINORPREGN-4-ENE-20-YNE-3-ONE-3E- AND -3Z-OXIME ISOMERS, AS WELL AS PROCESS FOR THE SYNTHESIS OF THE MIXTURE OF ISOMERS AND THE PURE ISOMERS

Publications (1)

Publication Number Publication Date
ATE470669T1 true ATE470669T1 (de) 2010-06-15

Family

ID=90001693

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04730317T ATE470669T1 (de) 2003-06-30 2004-04-29 D-(17alpha)-13-ethyl-17hydroxy-18,19-dinorpregn 4-ene-20-yne-3-one in form des reinen 3e- und 3z- oximes sowie das verfahren zur herstellung der mischung der isomere wie auch der reinen isomere

Country Status (17)

Country Link
EP (1) EP1641812B1 (de)
JP (1) JP2007534617A (de)
CN (1) CN100497368C (de)
AT (1) ATE470669T1 (de)
AU (1) AU2004251117A1 (de)
BR (1) BRPI0411734A (de)
CA (1) CA2526305A1 (de)
DE (1) DE602004027629D1 (de)
EA (1) EA008174B1 (de)
HR (1) HRP20060040A2 (de)
HU (1) HUP0301981A2 (de)
MX (1) MXPA05012655A (de)
NO (1) NO20060456L (de)
NZ (1) NZ544481A (de)
RS (1) RS20050816A (de)
UA (1) UA85190C2 (de)
WO (1) WO2005000867A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6734277B2 (en) 2002-05-09 2004-05-11 General Electric Company Method of enhancing pit replication in optical disks
US7576226B2 (en) 2003-06-30 2009-08-18 Richter Gedeon Vegyeszeti Gyar Rt. Process of making isomers of norelgestromin and methods using the same
JP2007508380A (ja) * 2004-08-12 2007-04-05 シコール インコーポレイティド ３−オキシイミノステロイドの調製方法
US20070098772A1 (en) * 2005-09-23 2007-05-03 Westcott Tyler D Transdermal norelgestromin delivery system

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1123104A (en) * 1965-10-22 1968-08-14 Ortho Pharma Corp 3-oxime-steroids and method of preparation
AT343292B (de) * 1973-03-01 1978-05-26 Ortho Pharma Corp Verfahren zur herstellung von neuen steroid-3-oxim-derivaten
US4027019A (en) * 1975-07-24 1977-05-31 Ortho Pharmaceutical Corporation 3-Oximes of D-17α-ethynyl-19-nortestosterone esters and method
JPS624400A (ja) * 1985-06-29 1987-01-10 内藤　喜之 マイクロ波用アンテナ
HU214598B (hu) * 1987-09-24 1998-04-28 Jencap Research Ltd Eljárás fogamzásgátló és hormonterápiához alkalmazható, ösztrogént és progesztint tartalmazó gyógyszerkészítmények előállítására
DK0836506T4 (da) * 1995-06-07 2012-01-30 Ortho Mcneil Pharm Inc Transdermalt plaster til indgivelse af 17-deacetyl norgestimat alene eller i kombination med et østrogen

Also Published As

Publication number Publication date
UA85190C2 (en) 2009-01-12
CN1798758A (zh) 2006-07-05
HRP20060040A2 (hr) 2007-08-31
WO2005000867A1 (en) 2005-01-06
RS20050816A (sr) 2007-08-03
MXPA05012655A (es) 2006-02-22
NO20060456L (no) 2006-03-30
CA2526305A1 (en) 2005-01-06
HUP0301981D0 (en) 2003-09-29
EP1641812A1 (de) 2006-04-05
JP2007534617A (ja) 2007-11-29
DE602004027629D1 (de) 2010-07-22
BRPI0411734A (pt) 2006-08-08
NZ544481A (en) 2009-05-31
EA200600120A1 (ru) 2006-06-30
AU2004251117A1 (en) 2005-01-06
EP1641812B1 (de) 2010-06-09
CN100497368C (zh) 2009-06-10
HUP0301981A2 (hu) 2005-04-28
EA008174B1 (ru) 2007-04-27

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