ATE471326T1 - Substituierte thienopyrrolcarbonsäureamide, pyrrolothiazolcarbonsäureamide und verwandte analoga als inhibitoren von caseinkinase-i- epsilon - Google Patents

Substituierte thienopyrrolcarbonsäureamide, pyrrolothiazolcarbonsäureamide und verwandte analoga als inhibitoren von caseinkinase-i- epsilon

Info

Publication number
ATE471326T1
ATE471326T1 AT05826812T AT05826812T ATE471326T1 AT E471326 T1 ATE471326 T1 AT E471326T1 AT 05826812 T AT05826812 T AT 05826812T AT 05826812 T AT05826812 T AT 05826812T AT E471326 T1 ATE471326 T1 AT E471326T1
Authority
AT
Austria
Prior art keywords
acid amides
thienopyrrolencarbononic
caseinkinase
carbononic
analogas
Prior art date
Application number
AT05826812T
Other languages
English (en)
Inventor
David Marc Fink
Yulin Chiang
Nicola Dawn Collar
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of ATE471326T1 publication Critical patent/ATE471326T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
AT05826812T 2004-08-19 2005-08-18 Substituierte thienopyrrolcarbonsäureamide, pyrrolothiazolcarbonsäureamide und verwandte analoga als inhibitoren von caseinkinase-i- epsilon ATE471326T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60334704P 2004-08-19 2004-08-19
PCT/US2005/029383 WO2006021000A2 (en) 2004-08-19 2005-08-18 Substituted thienopyrrole carboxylic acid amides, pyrrolothiazole carboxylic acid amides, and related analogs as inhibitors of casein kinase i epsilon

Publications (1)

Publication Number Publication Date
ATE471326T1 true ATE471326T1 (de) 2010-07-15

Family

ID=35695546

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05826812T ATE471326T1 (de) 2004-08-19 2005-08-18 Substituierte thienopyrrolcarbonsäureamide, pyrrolothiazolcarbonsäureamide und verwandte analoga als inhibitoren von caseinkinase-i- epsilon

Country Status (30)

Country Link
US (2) US7393867B2 (de)
EP (1) EP1784409B1 (de)
JP (1) JP4869232B2 (de)
KR (1) KR20070045263A (de)
CN (1) CN100562521C (de)
AR (1) AR051008A1 (de)
AT (1) ATE471326T1 (de)
AU (1) AU2005272584B2 (de)
BR (1) BRPI0514419A (de)
CA (1) CA2577879C (de)
CY (1) CY1110775T1 (de)
DE (1) DE602005021889D1 (de)
DK (1) DK1784409T3 (de)
ES (1) ES2347166T3 (de)
GT (1) GT200500215A (de)
HR (1) HRP20100475T1 (de)
IL (1) IL181158A0 (de)
JO (1) JO2629B1 (de)
MY (1) MY139831A (de)
PA (1) PA8642801A1 (de)
PE (1) PE20060630A1 (de)
PL (1) PL1784409T3 (de)
PT (1) PT1784409E (de)
RS (1) RS51413B (de)
RU (1) RU2403257C2 (de)
SI (1) SI1784409T1 (de)
SV (1) SV2006002190A (de)
TW (1) TWI372149B (de)
UY (1) UY29077A1 (de)
WO (1) WO2006021000A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004312530A1 (en) 2003-12-29 2005-07-21 Sepracor Inc. Pyrrole and pyrazole DAAO inhibitors
NZ569608A (en) 2006-01-06 2011-09-30 Sepracor Inc Tetralone-based monoamine reuptake inhibitors
BRPI0706365A2 (pt) 2006-01-06 2011-03-22 Sepracor Inc Cicloalquilaminas como inibidores da recaptação de monoamina
DK2816024T3 (en) 2006-03-31 2017-10-30 Sunovion Pharmaceuticals Inc CHIRALE AMINER
US7884124B2 (en) 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US7902252B2 (en) 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
EP1955699A1 (de) * 2007-02-08 2008-08-13 Boehringer Ingelheim Pharma GmbH & Co. KG Verwendung von Flibanserin zur Behandlung von Schlaflosigkeit
AU2008259841B2 (en) 2007-05-31 2015-02-05 Sunovion Pharmaceuticals Inc. Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors
JP4748823B2 (ja) * 2009-02-12 2011-08-17 株式会社ファルマデザイン カゼインキナーゼ１δ及びカゼインキナーゼ１ε阻害剤
NZ596616A (en) * 2009-05-28 2013-05-31 Vertex Pharma Aminopyrazole triazolothiadiazole inhibitors of c-met protien kinase
SI2493876T1 (sl) * 2009-10-28 2014-04-30 Pfizer Inc. Derivati imidazola kot inhibitorji kazein-kinaze
DE102009058280A1 (de) * 2009-12-14 2011-06-16 Merck Patent Gmbh Thiazolderivate
JP5181156B2 (ja) * 2010-08-09 2013-04-10 株式会社ファルマデザイン カゼインキナーゼ１δ及びカゼインキナーゼ１ε阻害剤
CN109748927A (zh) * 2017-11-03 2019-05-14 上海交通大学医学院附属瑞金医院 杂芳基酰胺类化合物、其制备方法、药用组合物及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9702001D0 (sv) * 1997-05-28 1997-05-28 Astra Pharma Prod Novel compounds
ATE322016T1 (de) * 1999-06-08 2006-04-15 Aventis Pharma Inc Screeningsverfahren zur änderung zirkadiane- rhythmus-eiweisse
ATE428711T1 (de) * 2003-12-11 2009-05-15 Aventis Pharma Inc Substituierte 1h-pyrroloä3,2-b, 3,2-c und 2,3- cüpyridin-2-carbonsäureamide und verwandte analoga als inhibitoren von caseinkinase-i- epsilon

Also Published As

Publication number Publication date
SI1784409T1 (sl) 2010-10-29
JP2008510712A (ja) 2008-04-10
US20070299112A1 (en) 2007-12-27
DK1784409T3 (da) 2010-09-27
US20080227822A1 (en) 2008-09-18
PL1784409T3 (pl) 2010-10-29
KR20070045263A (ko) 2007-05-02
GT200500215A (es) 2006-03-27
EP1784409B1 (de) 2010-06-16
PA8642801A1 (es) 2006-05-16
DE602005021889D1 (en) 2010-07-29
TW200621788A (en) 2006-07-01
HRP20100475T1 (hr) 2010-10-31
US7652046B2 (en) 2010-01-26
WO2006021000A2 (en) 2006-02-23
US7393867B2 (en) 2008-07-01
JO2629B1 (en) 2012-06-24
EP1784409A2 (de) 2007-05-16
UY29077A1 (es) 2006-03-31
SV2006002190A (es) 2006-05-24
AR051008A1 (es) 2006-12-13
PE20060630A1 (es) 2006-08-03
BRPI0514419A (pt) 2008-06-10
AU2005272584A1 (en) 2006-02-23
JP4869232B2 (ja) 2012-02-08
ES2347166T3 (es) 2010-10-26
MY139831A (en) 2009-10-30
CN100562521C (zh) 2009-11-25
PT1784409E (pt) 2010-09-06
RU2007109812A (ru) 2008-09-27
RS51413B (sr) 2011-02-28
IL181158A0 (en) 2007-07-04
CA2577879A1 (en) 2006-02-23
WO2006021000A3 (en) 2006-06-15
CN101001861A (zh) 2007-07-18
RU2403257C2 (ru) 2010-11-10
HK1105198A1 (en) 2008-02-06
CY1110775T1 (el) 2015-06-10
TWI372149B (en) 2012-09-11
CA2577879C (en) 2011-07-12
AU2005272584B2 (en) 2010-11-11

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