ATE471386T1 - Verfahren für die dynamische kinetische racematspaltung (dkr) racemischer verbindungen in fluorkohlen(wasser)stofflösungsmitteln - Google Patents

Verfahren für die dynamische kinetische racematspaltung (dkr) racemischer verbindungen in fluorkohlen(wasser)stofflösungsmitteln

Info

Publication number
ATE471386T1
ATE471386T1 AT07732468T AT07732468T ATE471386T1 AT E471386 T1 ATE471386 T1 AT E471386T1 AT 07732468 T AT07732468 T AT 07732468T AT 07732468 T AT07732468 T AT 07732468T AT E471386 T1 ATE471386 T1 AT E471386T1
Authority
AT
Austria
Prior art keywords
compound
fluorocarbon
compounds
racemix
racemat
Prior art date
Application number
AT07732468T
Other languages
English (en)
Inventor
Jason Micklefield
Anthony Ball
Stuart Corr
Original Assignee
Ineos Fluor Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ineos Fluor Holdings Ltd filed Critical Ineos Fluor Holdings Ltd
Application granted granted Critical
Publication of ATE471386T1 publication Critical patent/ATE471386T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
AT07732468T 2006-04-21 2007-04-19 Verfahren für die dynamische kinetische racematspaltung (dkr) racemischer verbindungen in fluorkohlen(wasser)stofflösungsmitteln ATE471386T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0607911.5A GB0607911D0 (en) 2006-04-21 2006-04-21 Process
PCT/GB2007/001426 WO2007129018A1 (en) 2006-04-21 2007-04-19 Process for dynamic kinetic resolution (dkr) of racemic compounds in (hydro) fluorocarbon solvents

Publications (1)

Publication Number Publication Date
ATE471386T1 true ATE471386T1 (de) 2010-07-15

Family

ID=36581012

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07732468T ATE471386T1 (de) 2006-04-21 2007-04-19 Verfahren für die dynamische kinetische racematspaltung (dkr) racemischer verbindungen in fluorkohlen(wasser)stofflösungsmitteln

Country Status (10)

Country Link
US (1) US20090280558A1 (de)
EP (1) EP2010666B1 (de)
JP (1) JP2009533067A (de)
AT (1) ATE471386T1 (de)
AU (1) AU2007246952B2 (de)
CA (1) CA2644268C (de)
DE (1) DE602007007204D1 (de)
ES (1) ES2360245T3 (de)
GB (1) GB0607911D0 (de)
WO (1) WO2007129018A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007288122A1 (en) * 2006-08-25 2008-02-28 The University Of Sydney Reaction system
FR2986804A1 (fr) * 2012-02-09 2013-08-16 Servier Lab Procede de synthese enzymatique de l'acide (7s) 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene 7-carboxylique ou de ses esters, et application a la synthese de l'ivabradine et de ses sels
CN104230667B (zh) * 2014-09-12 2016-04-06 王际宽 R-3,5-双三氟甲基苯乙醇的制备
CN104388516A (zh) * 2014-10-08 2015-03-04 王同俊 (r)-(+)-3-氯-1-苯丙醇的制备
EP3523280B1 (de) * 2016-10-06 2026-03-11 Janssen Pharmaceutica NV Verfahren und zwischenprodukte zur herstellung eines btk-hemmers

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0725707B2 (ja) * 1989-04-14 1995-03-22 昭和電工株式会社 １，１，１，２―テトラフルオロエタンの精製法
DE4422045A1 (de) * 1994-06-26 1996-01-04 Hoechst Schering Agrevo Gmbh Verfahren zur enzymatischen Spaltung von 2-Amino-4-methylphosphinobutansäureamid-Derivaten
US6201151B1 (en) * 1998-12-17 2001-03-13 National Science Council Of Republic Of China Processes for preparing optically active (S)-α-aryl propionic acid or ester therof
JP2003512034A (ja) * 1999-10-18 2003-04-02 サムソン ファイン ケミカルズ カンパニー リミテッド キラルエステルの製造方法
AUPR732601A0 (en) * 2001-08-28 2001-09-20 Polychip Pharmaceuticals Pty Ltd Methods for the synthesis of amines such as ephedrine and inter mediates
KR100644165B1 (ko) * 2002-03-14 2006-11-10 학교법인 포항공과대학교 아미노시클로펜타디에닐 루테늄 촉매를 이용한 키랄화합물 분할 방법
GB0306267D0 (en) * 2003-03-19 2003-04-23 Ineos Fluor Ltd Process

Also Published As

Publication number Publication date
AU2007246952A1 (en) 2007-11-15
JP2009533067A (ja) 2009-09-17
WO2007129018A1 (en) 2007-11-15
US20090280558A1 (en) 2009-11-12
EP2010666A1 (de) 2009-01-07
EP2010666B1 (de) 2010-06-16
AU2007246952B2 (en) 2010-10-28
CA2644268C (en) 2012-01-17
GB0607911D0 (en) 2006-05-31
ES2360245T3 (es) 2011-06-02
CA2644268A1 (en) 2007-11-15
DE602007007204D1 (de) 2010-07-29

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