ATE471386T1 - Verfahren für die dynamische kinetische racematspaltung (dkr) racemischer verbindungen in fluorkohlen(wasser)stofflösungsmitteln - Google Patents

Verfahren für die dynamische kinetische racematspaltung (dkr) racemischer verbindungen in fluorkohlen(wasser)stofflösungsmitteln

Info

Publication number: ATE471386T1
Authority: AT; Austria
Prior art keywords: compound; fluorocarbon; compounds; racemix; racemat
Prior art date: 2006-04-21

Application number

AT07732468T

Other languages

English (en)

Inventor

Jason Micklefield

Anthony Ball

Stuart Corr

Original Assignee

Ineos Fluor Holdings Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-04-21

Filing date

2007-04-19

Publication date

2010-07-15

2007-04-19 Application filed by Ineos Fluor Holdings Ltd filed Critical Ineos Fluor Holdings Ltd

2010-07-15 Application granted granted Critical

2010-07-15 Publication of ATE471386T1 publication Critical patent/ATE471386T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 9
238000000034 method Methods 0.000 title abstract 3
NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 title abstract 2
239000002904 solvent Substances 0.000 title abstract 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
239000003054 catalyst Substances 0.000 abstract 4
239000000758 substrate Substances 0.000 abstract 2
102000004190 Enzymes Human genes 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
ZZUFCTLCJUWOSV-UHFFFAOYSA-N furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Analytical Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Glass Compositions (AREA)
Iron Core Of Rotating Electric Machines (AREA)

AT07732468T 2006-04-21 2007-04-19 Verfahren für die dynamische kinetische racematspaltung (dkr) racemischer verbindungen in fluorkohlen(wasser)stofflösungsmitteln ATE471386T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0607911.5A GB0607911D0 (en)	2006-04-21	2006-04-21	Process
PCT/GB2007/001426 WO2007129018A1 (en)	2006-04-21	2007-04-19	Process for dynamic kinetic resolution (dkr) of racemic compounds in (hydro) fluorocarbon solvents

Publications (1)

Publication Number	Publication Date
ATE471386T1 true ATE471386T1 (de)	2010-07-15

Family

ID=36581012

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT07732468T ATE471386T1 (de)	2006-04-21	2007-04-19	Verfahren für die dynamische kinetische racematspaltung (dkr) racemischer verbindungen in fluorkohlen(wasser)stofflösungsmitteln

Country Status (10)

Country	Link
US (1)	US20090280558A1 (de)
EP (1)	EP2010666B1 (de)
JP (1)	JP2009533067A (de)
AT (1)	ATE471386T1 (de)
AU (1)	AU2007246952B2 (de)
CA (1)	CA2644268C (de)
DE (1)	DE602007007204D1 (de)
ES (1)	ES2360245T3 (de)
GB (1)	GB0607911D0 (de)
WO (1)	WO2007129018A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20100081849A1 (en) *	2006-08-25	2010-04-01	The University Of Sydney	Reaction system
FR2986804A1 (fr) *	2012-02-09	2013-08-16	Servier Lab	Procede de synthese enzymatique de l'acide (7s) 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene 7-carboxylique ou de ses esters, et application a la synthese de l'ivabradine et de ses sels
CN104230667B (zh) *	2014-09-12	2016-04-06	王际宽	R-3,5-双三氟甲基苯乙醇的制备
CN104388516A (zh) *	2014-10-08	2015-03-04	王同俊	(r)-(+)-3-氯-1-苯丙醇的制备
JP7590810B2 (ja) *	2016-10-06	2024-11-27	ヤンセンファーマシューティカエヌ．ベー．	Ｂｔｋ阻害剤を調製するための方法および中間体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0725707B2 (ja) *	1989-04-14	1995-03-22	昭和電工株式会社	１，１，１，２―テトラフルオロエタンの精製法
DE4422045A1 (de) *	1994-06-26	1996-01-04	Hoechst Schering Agrevo Gmbh	Verfahren zur enzymatischen Spaltung von 2-Amino-4-methylphosphinobutansäureamid-Derivaten
US6201151B1 (en) *	1998-12-17	2001-03-13	National Science Council Of Republic Of China	Processes for preparing optically active (S)-α-aryl propionic acid or ester therof
CN1390192A (zh) *	1999-10-18	2003-01-08	三星精密化学株式会社	手性酯的制备方法
AUPR732601A0 (en) *	2001-08-28	2001-09-20	Polychip Pharmaceuticals Pty Ltd	Methods for the synthesis of amines such as ephedrine and inter mediates
KR100644165B1 (ko) *	2002-03-14	2006-11-10	학교법인 포항공과대학교	아미노시클로펜타디에닐 루테늄 촉매를 이용한 키랄화합물 분할 방법
GB0306267D0 (en) *	2003-03-19	2003-04-23	Ineos Fluor Ltd	Process

2006
- 2006-04-21 GB GBGB0607911.5A patent/GB0607911D0/en not_active Ceased
2007
- 2007-04-19 US US12/297,024 patent/US20090280558A1/en not_active Abandoned
- 2007-04-19 ES ES07732468T patent/ES2360245T3/es active Active
- 2007-04-19 WO PCT/GB2007/001426 patent/WO2007129018A1/en not_active Ceased
- 2007-04-19 JP JP2009505954A patent/JP2009533067A/ja active Pending
- 2007-04-19 EP EP07732468A patent/EP2010666B1/de not_active Not-in-force
- 2007-04-19 DE DE602007007204T patent/DE602007007204D1/de active Active
- 2007-04-19 CA CA2644268A patent/CA2644268C/en not_active Expired - Fee Related
- 2007-04-19 AT AT07732468T patent/ATE471386T1/de not_active IP Right Cessation
- 2007-04-19 AU AU2007246952A patent/AU2007246952B2/en not_active Ceased

Also Published As

Publication number	Publication date
AU2007246952A1 (en)	2007-11-15
EP2010666B1 (de)	2010-06-16
WO2007129018A1 (en)	2007-11-15
EP2010666A1 (de)	2009-01-07
US20090280558A1 (en)	2009-11-12
DE602007007204D1 (de)	2010-07-29
JP2009533067A (ja)	2009-09-17
CA2644268C (en)	2012-01-17
ES2360245T3 (es)	2011-06-02
AU2007246952B2 (en)	2010-10-28
CA2644268A1 (en)	2007-11-15
GB0607911D0 (en)	2006-05-31

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Legal Events

Date	Code	Title	Description
2010-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties