ATE473438T1 - Zuführung von molekülen an eine lipiddoppelschicht - Google Patents

Zuführung von molekülen an eine lipiddoppelschicht

Info

Publication number
ATE473438T1
ATE473438T1 AT06726479T AT06726479T ATE473438T1 AT E473438 T1 ATE473438 T1 AT E473438T1 AT 06726479 T AT06726479 T AT 06726479T AT 06726479 T AT06726479 T AT 06726479T AT E473438 T1 ATE473438 T1 AT E473438T1
Authority
AT
Austria
Prior art keywords
molecule
lipide
molecules
delivery
double layer
Prior art date
Application number
AT06726479T
Other languages
English (en)
Inventor
John Hagan Pryce Bayley
Matthew Alexander Holden
Original Assignee
Isis Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Innovation filed Critical Isis Innovation
Application granted granted Critical
Publication of ATE473438T1 publication Critical patent/ATE473438T1/de

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Sustainable Development (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT06726479T 2005-03-23 2006-03-22 Zuführung von molekülen an eine lipiddoppelschicht ATE473438T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0505971.2A GB0505971D0 (en) 2005-03-23 2005-03-23 Delivery of molecules to a lipid bilayer
PCT/GB2006/001057 WO2006100484A2 (en) 2005-03-23 2006-03-22 Deliver of molecules to a li id bila

Publications (1)

Publication Number Publication Date
ATE473438T1 true ATE473438T1 (de) 2010-07-15

Family

ID=34531741

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06726479T ATE473438T1 (de) 2005-03-23 2006-03-22 Zuführung von molekülen an eine lipiddoppelschicht

Country Status (7)

Country Link
US (1) US7939270B2 (de)
EP (1) EP1861071B1 (de)
JP (1) JP5253148B2 (de)
AT (1) ATE473438T1 (de)
DE (1) DE602006015292D1 (de)
GB (1) GB0505971D0 (de)
WO (1) WO2006100484A2 (de)

Families Citing this family (178)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4159298B2 (ja) 2001-09-04 2008-10-01 シャープ株式会社 電気掃除機及び機器
US9233846B2 (en) 2005-10-14 2016-01-12 The Regents Of The University Of California Formation and encapsulation of molecular bilayer and monolayer membranes
GB0523282D0 (en) 2005-11-15 2005-12-21 Isis Innovation Methods using pores
US9415422B2 (en) 2006-03-10 2016-08-16 Siemens Industry, Inc. Mail sorting system
CN101495656B (zh) * 2006-06-07 2017-02-08 纽约哥伦比亚大学理事会 采用带修饰的核苷酸通过纳米通道进行dna序列测定
EP2122344B8 (de) * 2007-02-20 2019-08-21 Oxford Nanopore Technologies Limited Lipiddoppelschicht-sensorsystem
GB2446823A (en) * 2007-02-20 2008-08-27 Oxford Nanolabs Ltd Formulation of lipid bilayers
GB2447043A (en) * 2007-02-20 2008-09-03 Oxford Nanolabs Ltd Lipid bilayer sensor system
WO2008124107A1 (en) 2007-04-04 2008-10-16 The Regents Of The University Of California Compositions, devices, systems, and methods for using a nanopore
GB0716264D0 (en) 2007-08-21 2007-09-26 Isis Innovation Bilayers
GB2453377A (en) 2007-10-05 2009-04-08 Isis Innovation Transmembrane protein pores and molecular adapters therefore.
WO2009073622A1 (en) 2007-11-30 2009-06-11 Electronic Bio Sciences, Llc Method and apparatus for single side bilayer formation
GB0724736D0 (en) 2007-12-19 2008-01-30 Oxford Nanolabs Ltd Formation of layers of amphiphilic molecules
US8772041B2 (en) * 2008-05-22 2014-07-08 The Regents Of The University Of California Membrane precursors and membranes formed therefrom
US20110229877A1 (en) 2008-07-07 2011-09-22 Oxford Nanopore Technologies Limited Enzyme-pore constructs
GB0820927D0 (en) 2008-11-14 2008-12-24 Isis Innovation Method
CN102482330A (zh) 2009-01-30 2012-05-30 牛津纳米孔技术有限公司 酶突变体
EP2391732B1 (de) 2009-01-30 2015-05-27 Oxford Nanopore Technologies Limited Verfahren die adaptoren zur nukleinsaure constructen für transmembrane sequenzierung benutzen
GB0905140D0 (en) 2009-03-25 2009-05-06 Isis Innovation Method
US9678055B2 (en) 2010-02-08 2017-06-13 Genia Technologies, Inc. Methods for forming a nanopore in a lipid bilayer
US8324914B2 (en) * 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
US9605307B2 (en) 2010-02-08 2017-03-28 Genia Technologies, Inc. Systems and methods for forming a nanopore in a lipid bilayer
EP2614156B1 (de) 2010-09-07 2018-08-01 The Regents of The University of California Bis auf ein nukleotid genaue steuerung der dna-bewegung in einer nanopore mithilfe eines prozessiven enzyms
CN103282518B (zh) 2010-12-17 2016-11-16 纽约哥伦比亚大学理事会 使用经修饰的核苷酸和纳米孔检测的dna边合成边测序
US9121059B2 (en) 2010-12-22 2015-09-01 Genia Technologies, Inc. Nanopore-based single molecule characterization
GB201100516D0 (en) 2011-01-12 2011-02-23 Isis Innovation Method using fluorinated amphiphiles
US8962242B2 (en) 2011-01-24 2015-02-24 Genia Technologies, Inc. System for detecting electrical properties of a molecular complex
US9110478B2 (en) 2011-01-27 2015-08-18 Genia Technologies, Inc. Temperature regulation of measurement arrays
BR112013020411B1 (pt) 2011-02-11 2021-09-08 Oxford Nanopore Technologies Limited Monômero de msp mutante, construto, polinucleotídeo, poro, kit e aparelho para caracterizar uma sequência de ácido nucleico alvo, e, método para caracterizar uma sequência de ácido nucleico alvo
US8968539B2 (en) 2011-03-08 2015-03-03 Electronic Biosciences, Inc. Methods for voltage-induced protein incorporation into planar lipid bilayers
SG10201604316WA (en) 2011-05-27 2016-07-28 Oxford Nanopore Tech Ltd Coupling method
KR20140050067A (ko) 2011-07-25 2014-04-28 옥스포드 나노포어 테크놀로지즈 리미티드 막횡단 포어를 사용한 이중 가닥 폴리뉴클레오티드 서열분석을 위한 헤어핀 루프 방법
US9150598B2 (en) * 2011-10-05 2015-10-06 The Regents Of The University Of California Masking apertures enabling automation and solution exchange in sessile bilayers
CN104039979B (zh) 2011-10-21 2016-08-24 牛津纳米孔技术公司 使用孔和Hel308解旋酶表征目标多核苷酸的酶方法
GB201119032D0 (en) 2011-11-03 2011-12-14 Isis Innovation Multisomes: encapsulated droplet networks
EP2798083B1 (de) 2011-12-29 2017-08-09 Oxford Nanopore Technologies Limited Verfahren zur charakterisierung einer polynukelotids mittels verwendung einer xpd-helikase
CA2861808C (en) 2011-12-29 2021-02-23 Oxford Nanopore Technologies Limited Enzyme method
GB201202519D0 (en) 2012-02-13 2012-03-28 Oxford Nanopore Tech Ltd Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules
CA2864035C (en) 2012-02-15 2021-05-18 Oxford Nanopore Technologies Limited A method for determining the presence of an analyte using an aptamer
EP3736339B1 (de) 2012-02-16 2022-07-27 Oxford Nanopore Technologies plc Analyse von messungen eines polymers
US8986629B2 (en) 2012-02-27 2015-03-24 Genia Technologies, Inc. Sensor circuit for controlling, detecting, and measuring a molecular complex
WO2013154999A2 (en) 2012-04-09 2013-10-17 The Trustees Of Columbia University In The City Of New York Method of preparation of nanopore and uses thereof
WO2013153359A1 (en) 2012-04-10 2013-10-17 Oxford Nanopore Technologies Limited Mutant lysenin pores
JP2015525077A (ja) 2012-06-15 2015-09-03 ジェニア・テクノロジーズ・インコーポレイテッド チップの構成および高精度な核酸配列決定
ES2779699T3 (es) 2012-06-20 2020-08-18 Univ Columbia Secuenciación de ácidos nucleicos mediante detección en nanoporos de moléculas de etiqueta
US11155860B2 (en) 2012-07-19 2021-10-26 Oxford Nanopore Technologies Ltd. SSB method
AU2013291763B2 (en) 2012-07-19 2019-06-20 Oxford Nanopore Technologies Limited Modified helicases
CA2879355C (en) 2012-07-19 2021-09-21 Oxford Nanopore Technologies Limited Helicase construct and its use in characterising polynucleotides
WO2014041337A1 (en) 2012-09-14 2014-03-20 Oxford Nanopore Technologies Limited Sample preparation method
GB201219201D0 (en) 2012-10-25 2012-12-12 Isis Innovation Hydrogel network
GB201219196D0 (en) 2012-10-25 2012-12-12 Isis Innovation Droplet assembly method
GB201313121D0 (en) 2013-07-23 2013-09-04 Oxford Nanopore Tech Ltd Array of volumes of polar medium
JP6375301B2 (ja) 2012-10-26 2018-08-15 オックスフォード ナノポール テクノロジーズ リミテッド 液滴界面
WO2014072703A1 (en) 2012-11-06 2014-05-15 Oxford Nanopore Technologies Limited Quadruplex method
US9605309B2 (en) 2012-11-09 2017-03-28 Genia Technologies, Inc. Nucleic acid sequencing using tags
CN105188934B (zh) 2012-12-07 2018-12-04 牛津大学创新有限公司 3d打印的液滴组件
GB201222928D0 (en) 2012-12-19 2013-01-30 Oxford Nanopore Tech Ltd Analysis of a polynucleotide
EP2746772B1 (de) 2012-12-20 2016-03-23 AIT Austrian Institute of Technology GmbH Lipidmembran-umhüllte Partikel mit Membranproteinen
US9759711B2 (en) 2013-02-05 2017-09-12 Genia Technologies, Inc. Nanopore arrays
GB201318465D0 (en) 2013-10-18 2013-12-04 Oxford Nanopore Tech Ltd Method
CA2901545C (en) 2013-03-08 2019-10-08 Oxford Nanopore Technologies Limited Use of spacer elements in a nucleic acid to control movement of a helicase
GB201314695D0 (en) 2013-08-16 2013-10-02 Oxford Nanopore Tech Ltd Method
US10732183B2 (en) 2013-03-15 2020-08-04 The Trustees Of Columbia University In The City Of New York Method for detecting multiple predetermined compounds in a sample
GB201313477D0 (en) 2013-07-29 2013-09-11 Univ Leuven Kath Nanopore biosensors for detection of proteins and nucleic acids
GB201316849D0 (en) 2013-09-23 2013-11-06 Isis Innovation Method
US9551697B2 (en) 2013-10-17 2017-01-24 Genia Technologies, Inc. Non-faradaic, capacitively coupled measurement in a nanopore cell array
EP3575410A3 (de) 2013-10-18 2020-03-04 Oxford Nanopore Technologies Limited Modifizierte enzyme
GB201406151D0 (en) 2014-04-04 2014-05-21 Oxford Nanopore Tech Ltd Method
US9567630B2 (en) 2013-10-23 2017-02-14 Genia Technologies, Inc. Methods for forming lipid bilayers on biochips
EP3060918B1 (de) 2013-10-23 2019-09-18 Genia Technologies, Inc. Schnelle molekulare erfassung mit nanoporen
ES2735015T3 (es) 2013-11-26 2019-12-13 Illumina Inc Composiciones y métodos para secuenciar polinucleótidos
EP2886663A1 (de) 2013-12-19 2015-06-24 Centre National de la Recherche Scientifique (CNRS) Nanoporensequenzierung mit replikativen Polymerasen und Helicasen
EP3097210B2 (de) 2014-01-22 2022-04-20 Oxford Nanopore Technologies Limited Verfahren zur anheftung eines oder mehrerer polynukleotid-bindenden proteine an ein zielpolynukleotid
GB201406155D0 (en) 2014-04-04 2014-05-21 Oxford Nanopore Tech Ltd Method
GB201403096D0 (en) 2014-02-21 2014-04-09 Oxford Nanopore Tech Ltd Sample preparation method
US10240195B2 (en) 2014-03-24 2019-03-26 The Trustees Of Columbia University In The City Of New York Chemical methods for producing tagged nucleotides
US10337060B2 (en) 2014-04-04 2019-07-02 Oxford Nanopore Technologies Ltd. Method for characterising a double stranded nucleic acid using a nano-pore and anchor molecules at both ends of said nucleic acid
US10443097B2 (en) 2014-05-02 2019-10-15 Oxford Nanopore Technologies Ltd. Method of improving the movement of a target polynucleotide with respect to a transmembrane pore
GB201417712D0 (en) 2014-10-07 2014-11-19 Oxford Nanopore Tech Ltd Method
EP3982121B1 (de) 2014-07-31 2024-04-24 Illumina, Inc. Nukleinsäuresequenzierung mit hybriden nanoporensensoren
CN119899249A (zh) 2014-09-01 2025-04-29 弗拉芒区生物技术研究所 突变csgg孔
US10266885B2 (en) 2014-10-07 2019-04-23 Oxford Nanopore Technologies Ltd. Mutant pores
GB201418159D0 (en) 2014-10-14 2014-11-26 Oxford Nanopore Tech Ltd Method
EP3971300B1 (de) 2014-10-16 2024-06-05 Oxford Nanopore Technologies plc Sortierung von polymeren
GB201418469D0 (en) 2014-10-17 2014-12-03 Oxford Nanopore Tech Ltd Method
GB201418512D0 (en) 2014-10-17 2014-12-03 Oxford Nanopore Tech Ltd Electrical device with detachable components
EP3250602A1 (de) 2015-01-26 2017-12-06 Cellectis T-zellenrezeptor-knockout-manipulierte immunzellen mit an cd123 bindenden chimären antigenrezeptoren zur behandlung von rezidivierenden/refraktären akuten myeloischen lymphomen oder blastischen plasmazytoiden dendritischen zellneoplasmen
GB201502810D0 (en) 2015-02-19 2015-04-08 Oxford Nanopore Tech Ltd Method
GB201502809D0 (en) 2015-02-19 2015-04-08 Oxford Nanopore Tech Ltd Mutant pore
CN107735686B (zh) 2015-04-14 2021-06-11 鲁汶天主教大学 具有内部蛋白质衔接子的纳米孔
CN109072295B (zh) 2015-12-08 2022-05-31 鲁汶大学研究与发展中心 修饰的纳米孔，包含其的组合物及其应用
KR102222191B1 (ko) 2016-03-02 2021-03-02 옥스포드 나노포어 테크놀로지즈 리미티드 돌연변이체 기공
CN118272512A (zh) 2016-04-06 2024-07-02 牛津纳米孔科技公开有限公司 突变体孔
EP3464616B1 (de) 2016-05-25 2022-05-04 Oxford Nanopore Technologies plc Verfahren
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
GB201609221D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
GB201611770D0 (en) 2016-07-06 2016-08-17 Oxford Nanopore Tech Microfluidic device
GB201616590D0 (en) 2016-09-29 2016-11-16 Oxford Nanopore Technologies Limited Method
JP2018059786A (ja) * 2016-10-04 2018-04-12 住友化学株式会社 嗅覚受容体複合体を用いた標的物質の検出装置及び検出方法並びに該検出装置の製造方法
GB201617886D0 (en) 2016-10-21 2016-12-07 Oxford Nanopore Technologies Limited Method
GB201620450D0 (en) 2016-12-01 2017-01-18 Oxford Nanopore Tech Ltd Method
CA3053086A1 (en) 2017-02-10 2018-08-16 Oxford Nanopore Technologies Limited Modified nanopores, compositions comprising the same, and uses thereof
GB201707122D0 (en) 2017-05-04 2017-06-21 Oxford Nanopore Tech Ltd Pore
GB201707140D0 (en) 2017-05-04 2017-06-21 Oxford Nanopore Tech Ltd Method
EP3645552B1 (de) 2017-06-30 2023-06-28 Vib Vzw Neue proteinporen
CN111225744B (zh) * 2017-10-23 2022-05-03 豪夫迈·罗氏有限公司 使用渗透不平衡除去和重新插入膜中的蛋白纳米孔
GB2568895B (en) 2017-11-29 2021-10-27 Oxford Nanopore Tech Ltd Microfluidic device
GB201801768D0 (en) 2018-02-02 2018-03-21 Oxford Nanopore Tech Ltd Synthesis method
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method
GB2574048B (en) 2018-05-24 2021-06-16 Oxford Nanopore Tech Ltd Nanopore sensor component with electrostatic discharge protection
GB201808556D0 (en) 2018-05-24 2018-07-11 Oxford Nanopore Tech Ltd Method
GB201809323D0 (en) 2018-06-06 2018-07-25 Oxford Nanopore Tech Ltd Method
GB201811623D0 (en) 2018-07-16 2018-08-29 Univ Oxford Innovation Ltd Molecular hopper
US12698528B2 (en) 2018-07-30 2026-08-04 Oxford University Innovation Limited Assembly comprising a nucleic acid scaffold, systems, methods, and uses therefore
JP7499761B2 (ja) 2018-11-08 2024-06-14 オックスフォード ナノポール テクノロジーズ ピーエルシー 細孔
GB201818216D0 (en) 2018-11-08 2018-12-26 Oxford Nanopore Tech Ltd Pore
GB201821155D0 (en) 2018-12-21 2019-02-06 Oxford Nanopore Tech Ltd Method
WO2020183172A1 (en) 2019-03-12 2020-09-17 Oxford Nanopore Technologies Inc. Nanopore sensing device and methods of operation and of forming it
GB2580988B (en) 2019-03-19 2022-04-13 Oxford Nanopore Tech Ltd Current measurement apparatus, molecular entity sensing apparatus, method of measuring a current, method of sensing a molecular entity
CN113677693B (zh) 2019-04-09 2025-10-21 牛津纳米孔科技公开有限公司 孔
GB201907246D0 (en) 2019-05-22 2019-07-03 Oxford Nanopore Tech Ltd Method
GB201907244D0 (en) 2019-05-22 2019-07-03 Oxford Nanopore Tech Ltd Method
GB201913997D0 (en) 2019-09-27 2019-11-13 Oxford Nanopore Tech Ltd Method
GB201915480D0 (en) 2019-10-25 2019-12-11 Oxford Nanopore Tech Ltd Improved nanopore sensing device, components and method of manufacture
GB201917060D0 (en) 2019-11-22 2020-01-08 Oxford Nanopore Tech Ltd Method
WO2021111125A1 (en) 2019-12-02 2021-06-10 Oxford Nanopore Technologies Limited Method of characterising a target polypeptide using a nanopore
GB201917742D0 (en) 2019-12-04 2020-01-15 Oxford Nanopore Tech Ltd Method
GB202004944D0 (en) 2020-04-03 2020-05-20 King S College London Method
GB202016874D0 (en) 2020-10-23 2020-12-09 Oxford Nanopore Tech Ltd Nanopore support structure and manufacture thereof
EP4168582B1 (de) 2020-06-18 2025-11-19 Oxford Nanopore Technologies plc Verfahren zur selektiven charakterisierung eines polynukleotids unter verwendung eines detektors
US20240076729A9 (en) 2020-06-18 2024-03-07 Oxford Nanopore Technologies Plc Method
GB202009349D0 (en) 2020-06-18 2020-08-05 Oxford Nanopore Tech Ltd Method
CN115989410A (zh) 2020-07-17 2023-04-18 牛津纳米孔科技公开有限公司 纳米孔感测装置
GB202015993D0 (en) 2020-10-08 2020-11-25 Oxford Nanopore Tech Ltd Method
GB202107192D0 (en) 2021-05-19 2021-06-30 Oxford Nanopore Tech Ltd Method
US20240240248A1 (en) 2021-05-19 2024-07-18 Oxford Nanopore Technologies Plc Methods for complement strand sequencing
GB202107354D0 (en) 2021-05-24 2021-07-07 Oxford Nanopore Tech Ltd Method
GB202112235D0 (en) 2021-08-26 2021-10-13 Oxford Nanopore Tech Ltd Nanopore
GB202118906D0 (en) 2021-12-23 2022-02-09 Oxford Nanopore Tech Ltd Method
GB202118939D0 (en) 2021-12-23 2022-02-09 Oxford Nanopore Tech Plc Pore
GB202118908D0 (en) 2021-12-23 2022-02-09 Oxford Nanopore Tech Ltd Method
GB202204919D0 (en) 2022-04-04 2022-05-18 Oxford Nanopore Tech Plc Method
GB202205617D0 (en) 2022-04-14 2022-06-01 Oxford Nanopore Tech Plc Novel modified protein pores and enzymes
CN119173641A (zh) 2022-05-17 2024-12-20 牛津纳米孔科技公开有限公司 方法和衔接子
CA3262948A1 (en) 2022-08-09 2024-02-15 Oxford Nanopore Technologies Plc NEW PORE-FORMING MONOMERS AND PORES
GB202211607D0 (en) 2022-08-09 2022-09-21 Oxford Nanopore Tech Plc Novel pore monomers and pores
AU2023322679A1 (en) 2022-08-09 2025-01-23 Oxford Nanopore Technologies Plc De novo pores
GB202211602D0 (en) 2022-08-09 2022-09-21 Oxford Nanopore Tech Plc Novel pore monomers and pores
CN120303290A (zh) 2022-10-28 2025-07-11 牛津纳米孔科技公开有限公司 孔单体和孔
GB202216162D0 (en) 2022-10-31 2022-12-14 Oxford Nanopore Tech Plc Method
GB202216905D0 (en) 2022-11-11 2022-12-28 Oxford Nanopore Tech Plc Novel pore monomers and pores
JP2026505839A (ja) 2023-02-07 2026-02-18 オックスフォード ユニヴァーシティ イノヴェーション リミテッド ナノポアを使用してペプチド、ポリペプチドまたはタンパク質を特徴付ける方法
GB202304324D0 (en) 2023-03-24 2023-05-10 Oxford Nanopore Tech Plc Method and kits
GB202305524D0 (en) 2023-04-14 2023-05-31 Oxford Nanopore Tech Plc Novel pore monomers and pores
GB202307141D0 (en) 2023-05-12 2023-06-28 Oxford Nanopore Tech Plc Modified helicases
GB202307486D0 (en) 2023-05-18 2023-07-05 Oxford Nanopore Tech Plc Method
GB202312709D0 (en) 2023-08-18 2023-10-04 Univ Oxford Innovation Ltd Nanopore
GB202313035D0 (en) 2023-08-25 2023-10-11 Univ Oxford Innovation Ltd Power unit
GB202315935D0 (en) 2023-10-18 2023-11-29 Oxford Nanopore Tech Ltd Novel enzymes
GB202317028D0 (en) 2023-11-06 2023-12-20 Oxford Nanopore Tech Ltd Method
WO2025160387A1 (en) * 2024-01-24 2025-07-31 The Rockefeller University Microscope for freestanding bilayer illumination
GB202405960D0 (en) 2024-04-29 2024-06-12 Oxford Nanopore Tech Plc Photo-active conjugates and their uses
GB202407055D0 (en) 2024-05-17 2024-07-03 Oxford Nanopore Tech Plc Enhanced polynucleotide sequencing
GB202407247D0 (en) 2024-05-21 2024-07-03 Oxford Nanopore Tech Plc Method
GB202407228D0 (en) 2024-05-21 2024-07-03 Oxford Nanopore Tech Plc Method
WO2026052811A2 (en) 2024-09-06 2026-03-12 Oxford Nanopore Technologies Plc Method
WO2026052817A1 (en) 2024-09-06 2026-03-12 Oxford Nanopore Technologies Plc Method
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GB202413618D0 (en) 2024-09-16 2024-10-30 Oxford Nanopore Tech Plc peptide characterisation
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WO2026120129A1 (en) 2024-12-06 2026-06-11 Oxford Nanopore Technologies plc. Pore constructs and their uses
GB202418735D0 (en) 2024-12-19 2025-02-05 Oxford Nanpore Tech Plc Methods and kits
GB202418836D0 (en) 2024-12-20 2025-02-05 Oxford Nanopore Tech Plc Method
GB202500688D0 (en) 2025-01-17 2025-03-05 Oxford Nanopore Tech Plc Pore monomers and their uses
GB202500666D0 (en) 2025-01-17 2025-03-05 Univ Oxford Innovation Ltd Nanopore
WO2026154167A1 (en) 2025-01-17 2026-07-23 Oxford Nanopore Technologies Plc Method
WO2026162912A1 (en) 2025-01-31 2026-08-06 Oxford Nanopore Technologies Plc Methods and systems for polymer measurements

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3799743A (en) 1971-11-22 1974-03-26 Alexander James Stable lysis responsive lipid bilayer
US6327410B1 (en) * 1997-03-14 2001-12-04 The Trustees Of Tufts College Target analyte sensors utilizing Microspheres
GB9712386D0 (en) * 1997-06-14 1997-08-13 Univ Coventry Biosensor
ATE294240T1 (de) * 1998-02-17 2005-05-15 Univ Cardiff Verfahren und kit, um biologische substanzen in plasmamembran und/oder zytosol einzuführen
ATE332306T1 (de) * 1998-08-31 2006-07-15 Gryphon Therapeutics Inc Chemische anknüpfung unter einbeziehung von einer lipid-matrix und herstellung von membranpolypeptiden
JP3665720B2 (ja) * 1999-09-24 2005-06-29 株式会社東芝 センサデバイス
ES2271253T3 (es) * 2001-01-18 2007-04-16 Newcastle University Ventures Limited Biosensor con proteinas transmembrana unidas covalentemente.
WO2003095669A1 (en) 2002-05-10 2003-11-20 The Texas A & M University System Stochastic sensing through covalent interactions
JP4394916B2 (ja) * 2003-09-19 2010-01-06 独立行政法人科学技術振興機構 人工脂質二重膜の形成装置および人工脂質二重膜の形成方法、並びにその利用
WO2005071405A1 (ja) * 2004-01-21 2005-08-04 Japan Science And Technology Agency 膜タンパク質分析用平面脂質二重膜の形成方法とその装置

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EP1861071B1 (de) 2010-07-07
US20080153150A1 (en) 2008-06-26
JP5253148B2 (ja) 2013-07-31
DE602006015292D1 (de) 2010-08-19
WO2006100484A3 (en) 2008-05-29
EP1861071A2 (de) 2007-12-05
US7939270B2 (en) 2011-05-10

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