BRPI0816426A2 - Dispositivo para investigar uma molécula, método para investigar uma molécula, substrato adequado para uso no dispositivo para investigar moléculas, método para sequenciar um ácido nucléico. - Google Patents
Dispositivo para investigar uma molécula, método para investigar uma molécula, substrato adequado para uso no dispositivo para investigar moléculas, método para sequenciar um ácido nucléico.Info
- Publication number
- BRPI0816426A2 BRPI0816426A2 BRPI0816426-6A2A BRPI0816426A BRPI0816426A2 BR PI0816426 A2 BRPI0816426 A2 BR PI0816426A2 BR PI0816426 A BRPI0816426 A BR PI0816426A BR PI0816426 A2 BRPI0816426 A2 BR PI0816426A2
- Authority
- BR
- Brazil
- Prior art keywords
- investigating
- molecula
- molecule
- nucleic acid
- molecules
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 238000012163 sequencing technique Methods 0.000 title 1
- 239000000758 substrate Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/701—Integrated with dissimilar structures on a common substrate
- Y10S977/702—Integrated with dissimilar structures on a common substrate having biological material component
- Y10S977/704—Nucleic acids, e.g. DNA or RNA
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/724—Devices having flexible or movable element
- Y10S977/733—Nanodiaphragm
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/778—Nanostructure within specified host or matrix material, e.g. nanocomposite films
- Y10S977/781—Possessing nonosized surface openings that extend partially into or completely through the host material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0717150.7A GB0717150D0 (en) | 2007-09-04 | 2007-09-04 | Apparatus and method |
| PCT/GB2008/050783 WO2009030953A1 (en) | 2007-09-04 | 2008-09-04 | Apparatus and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0816426A2 true BRPI0816426A2 (pt) | 2015-03-03 |
Family
ID=38640188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0816426-6A2A BRPI0816426A2 (pt) | 2007-09-04 | 2008-09-04 | Dispositivo para investigar uma molécula, método para investigar uma molécula, substrato adequado para uso no dispositivo para investigar moléculas, método para sequenciar um ácido nucléico. |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8865455B2 (pt) |
| EP (1) | EP2188618B1 (pt) |
| JP (2) | JP2010538290A (pt) |
| CN (2) | CN103087904A (pt) |
| BR (1) | BRPI0816426A2 (pt) |
| CA (1) | CA2698876A1 (pt) |
| ES (1) | ES2617089T3 (pt) |
| GB (1) | GB0717150D0 (pt) |
| WO (1) | WO2009030953A1 (pt) |
Families Citing this family (50)
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| WO2009020682A2 (en) | 2007-05-08 | 2009-02-12 | The Trustees Of Boston University | Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof |
| GB0717150D0 (en) * | 2007-09-04 | 2007-10-17 | Univ Warwick | Apparatus and method |
| EP2196796A1 (en) * | 2008-12-09 | 2010-06-16 | Imec | Single molecule optical spectroscopy in solid-state nanopores in a transmission-based approach |
| EP2483680A4 (en) | 2009-09-30 | 2014-01-01 | Quantapore Inc | ULTRASOUND SEQUENCING OF BIOLOGICAL POLYMERS WITH THE HELP OF A MARKED NANOPORE |
| US8748091B2 (en) * | 2009-12-18 | 2014-06-10 | The Board Of Trustees Of The University Of Illinois | Characterizing stretched polynucleotides in a synthetic nanopassage |
| AU2011218847B2 (en) * | 2010-02-23 | 2015-03-12 | Christopher Gordon Atwood | Methods for the detection of biologically relevant molecules and their interaction characteristics |
| US10010272B2 (en) | 2010-05-27 | 2018-07-03 | Profusa, Inc. | Tissue-integrating electronic apparatus |
| EP2402738A3 (en) * | 2010-07-02 | 2012-01-11 | Imec | Spectroscopy using nanopore cavities |
| CN103069267B (zh) * | 2010-09-29 | 2016-05-11 | 株式会社日立高新技术 | 生物聚合物的光学的解析装置以及方法 |
| WO2012048150A1 (en) | 2010-10-06 | 2012-04-12 | Profusa, Inc. | Tissue-integrating sensors |
| US9274053B2 (en) * | 2011-05-18 | 2016-03-01 | Uvic Industry Partnerships Inc. | Flow through metallic nanohole arrays |
| WO2012165400A1 (ja) * | 2011-06-03 | 2012-12-06 | 株式会社日立ハイテクノロジーズ | 生体ポリマーの光学的解析装置及び方法 |
| GB2493397A (en) | 2011-08-05 | 2013-02-06 | Base4 Innovation Ltd | Pulse counter for single photon events |
| US9007576B2 (en) | 2011-08-12 | 2015-04-14 | Savannah River Nuclear Solutions, Llc | Surface enhanced Raman scattering spectroscopic waveguide |
| WO2013039778A2 (en) | 2011-09-12 | 2013-03-21 | The University Of North Carolina At Chapel Hill | Devices with a fluid transport nanochannel intersected by a fluid sensing nanochannel and related methods |
| AU2012339711B2 (en) * | 2011-11-14 | 2014-10-16 | Brigham Young University | Two- chamber dual-pore device |
| GB2497784A (en) * | 2011-12-20 | 2013-06-26 | Base4 Innovation Ltd | Identification of polymers using nanopore devices |
| JP6339024B2 (ja) * | 2012-02-10 | 2018-06-06 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルThe University Of North Carolina At Chapel Hill | 流体ナノファンネルを有する装置、関連する方法、製造及び解析システム |
| GB201212135D0 (en) * | 2012-07-09 | 2012-08-22 | Base4 Innovation Ltd | Improved sequencing apparatus |
| CN110579435B (zh) | 2012-10-15 | 2023-09-26 | 纳诺赛莱克特生物医药股份有限公司 | 颗粒分选的系统、设备和方法 |
| US9651539B2 (en) | 2012-10-28 | 2017-05-16 | Quantapore, Inc. | Reducing background fluorescence in MEMS materials by low energy ion beam treatment |
| GB201301178D0 (en) * | 2013-01-23 | 2013-03-06 | Dynamic Biosensors Gmbh | Method for sequencing a template nucleic acid immobilized on a substrate |
| KR20150132125A (ko) | 2013-02-28 | 2015-11-25 | 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 | 거대분자의 통제된 포획, 고정, 및 전달을 위한 통합된 부품을 가진 나노유체 장치 및 관련 분석 방법 |
| US9255288B2 (en) | 2013-03-13 | 2016-02-09 | The University Of North Carolina At Chapel Hill | Nanofluidic devices for the rapid mapping of whole genomes and related systems and methods of analysis |
| US20160003732A1 (en) * | 2013-03-14 | 2016-01-07 | Hewlett-Packard Development Company, L.P. | Devices to detect a substance and methods of producing such a device |
| WO2014158988A1 (en) | 2013-03-14 | 2014-10-02 | Profusa, Inc. | Method and device for correcting optical signals |
| GB201306446D0 (en) * | 2013-04-09 | 2013-05-22 | Base4 Innovation Ltd | Nanopore plasmonic detector |
| GB201306447D0 (en) * | 2013-04-09 | 2013-05-22 | Base4 Innovation Ltd | Plasmonic detector |
| AU2014270410B2 (en) | 2013-05-24 | 2020-07-16 | Illumina Cambridge Limited | Pyrophosphorolytic sequencing |
| CA2910019A1 (en) | 2013-05-24 | 2014-11-27 | Quantapore, Inc. | Nanopore-based nucleic acid analysis with mixed fret detection |
| JP2014235043A (ja) * | 2013-05-31 | 2014-12-15 | キヤノン株式会社 | 検査器具、検査システム、および検査方法 |
| US10219729B2 (en) | 2013-06-06 | 2019-03-05 | Profusa, Inc. | Apparatus and methods for detecting optical signals from implanted sensors |
| WO2015081294A2 (en) * | 2013-11-26 | 2015-06-04 | Stc.Unm | Innovative nanopore sequencing technology |
| US10612084B2 (en) * | 2014-04-08 | 2020-04-07 | International Business Machines Corporation | Reduction of entropic barrier of polyelectrolyte molecules in a nanopore device with agarose gel |
| EP2995934A1 (en) | 2014-09-15 | 2016-03-16 | Base4 Innovation Ltd | Improved nanopore plasmonic analyser |
| EP2995933A1 (en) | 2014-09-15 | 2016-03-16 | Base4 Innovation Ltd | Improved nanopore plasmonic analyser |
| ES2789000T3 (es) | 2014-10-10 | 2020-10-23 | Quantapore Inc | Análisis de polinucleótidos basado en nanoporos con marcadores fluorescentes que se inactivan mutuamente |
| CN107002126B (zh) * | 2014-10-24 | 2021-05-25 | 昆塔波尔公司 | 使用纳米结构阵列的聚合物的高效光学分析 |
| HK1245348A1 (zh) * | 2015-02-02 | 2018-08-24 | 奥特拉公司 | 来自样品背景的靶多核苷酸的纳米孔隙检测 |
| US10471428B2 (en) | 2015-05-11 | 2019-11-12 | The University Of North Carolina At Chapel Hill | Fluidic devices with nanoscale manifolds for molecular transport, related systems and methods of analysis |
| JP6559187B2 (ja) * | 2016-07-01 | 2019-08-14 | ツィンファ ユニバーシティ | 単一分子検出用のキャリア及び単一分子検出装置 |
| CN107561053B (zh) * | 2016-07-01 | 2020-04-28 | 清华大学 | 一种单分子检测方法 |
| JP2019522983A (ja) | 2016-07-05 | 2019-08-22 | クアンタポール, インコーポレイテッド | 光学ベースのナノポア配列決定 |
| WO2018119400A1 (en) | 2016-12-22 | 2018-06-28 | Profusa, Inc. | System and single-channel luminescent sensor for and method of determining analyte value |
| JP7272967B2 (ja) | 2017-06-20 | 2023-05-12 | イラミーナ インコーポレーテッド | ナノポアシーケンサー |
| EP3441143B1 (en) * | 2017-08-08 | 2022-04-13 | Roche Diagnostics GmbH | Laboratory instrument base plate |
| CN114846130A (zh) * | 2019-12-03 | 2022-08-02 | 国立研究开发法人科学技术振兴机构 | 纳米孔结构体及包含纳米孔结构体的碱基序列分析装置 |
| WO2022165276A1 (en) | 2021-01-29 | 2022-08-04 | Armonica Technologies, Inc. | Enhancement structures for surface-enhanced raman scattering |
| US20230055537A1 (en) * | 2021-08-18 | 2023-02-23 | University Of South Florida | Multi-modal nanopore sensors for nucleic acid sequencing |
| CN118401821A (zh) * | 2021-11-19 | 2024-07-26 | 国立大学法人北海道大学 | 微粒试样的光谱数据的生成方法、微粒的分析方法、微粒的判别方法、有无来自癌细胞的外泌体的判定方法、微粒的光谱测量用基板、微粒的光谱测量用器件和微粒的光谱测量用装置 |
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-
2007
- 2007-09-04 GB GBGB0717150.7A patent/GB0717150D0/en not_active Ceased
-
2008
- 2008-09-04 EP EP08788753.5A patent/EP2188618B1/en not_active Not-in-force
- 2008-09-04 JP JP2010523597A patent/JP2010538290A/ja active Pending
- 2008-09-04 US US12/676,472 patent/US8865455B2/en not_active Expired - Fee Related
- 2008-09-04 CN CN2012102917016A patent/CN103087904A/zh active Pending
- 2008-09-04 CA CA2698876A patent/CA2698876A1/en not_active Abandoned
- 2008-09-04 WO PCT/GB2008/050783 patent/WO2009030953A1/en not_active Ceased
- 2008-09-04 BR BRPI0816426-6A2A patent/BRPI0816426A2/pt not_active IP Right Cessation
- 2008-09-04 ES ES08788753.5T patent/ES2617089T3/es active Active
- 2008-09-04 CN CN2008801144811A patent/CN101842692B/zh not_active Expired - Fee Related
-
2012
- 2012-04-30 US US13/459,612 patent/US8440403B2/en not_active Expired - Fee Related
-
2014
- 2014-03-12 JP JP2014048399A patent/JP5827360B2/ja not_active Expired - Fee Related
- 2014-09-19 US US14/490,935 patent/US20150001085A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2188618B1 (en) | 2016-10-26 |
| US8440403B2 (en) | 2013-05-14 |
| EP2188618A1 (en) | 2010-05-26 |
| CN101842692B (zh) | 2012-09-12 |
| US20110036994A1 (en) | 2011-02-17 |
| JP2010538290A (ja) | 2010-12-09 |
| JP2014145771A (ja) | 2014-08-14 |
| ES2617089T3 (es) | 2017-06-15 |
| GB0717150D0 (en) | 2007-10-17 |
| JP5827360B2 (ja) | 2015-12-02 |
| US20120237940A1 (en) | 2012-09-20 |
| US8865455B2 (en) | 2014-10-21 |
| US20150001085A1 (en) | 2015-01-01 |
| CN103087904A (zh) | 2013-05-08 |
| CA2698876A1 (en) | 2009-03-12 |
| WO2009030953A1 (en) | 2009-03-12 |
| CN101842692A (zh) | 2010-09-22 |
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