CL2011000919A1 - Compuestos derivados de n-fenil-4-oxo-(1,4-dihidroquinolin o 1h-quinolin)-3-carboxamida, moduladores del regulador de conductancia transmembrana de fibrosis quistica (cftr); compuestos intermediarios; composicion farmaceutica; kit farmaceutico; proceso de preparacion; y uso para el tratamiento de fibrosis quistica, diabetes, entre otros. - Google Patents
Compuestos derivados de n-fenil-4-oxo-(1,4-dihidroquinolin o 1h-quinolin)-3-carboxamida, moduladores del regulador de conductancia transmembrana de fibrosis quistica (cftr); compuestos intermediarios; composicion farmaceutica; kit farmaceutico; proceso de preparacion; y uso para el tratamiento de fibrosis quistica, diabetes, entre otros.Info
- Publication number
- CL2011000919A1 CL2011000919A1 CL2011000919A CL2011000919A CL2011000919A1 CL 2011000919 A1 CL2011000919 A1 CL 2011000919A1 CL 2011000919 A CL2011000919 A CL 2011000919A CL 2011000919 A CL2011000919 A CL 2011000919A CL 2011000919 A1 CL2011000919 A1 CL 2011000919A1
- Authority
- CL
- Chile
- Prior art keywords
- cystic fibrosis
- compounds
- dihydroquinolin
- cftr
- quinolin
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- IRFSXVIRXMYULF-UHFFFAOYSA-N 1,2-dihydroquinoline Chemical compound C1=CC=C2C=CCNC2=C1 IRFSXVIRXMYULF-UHFFFAOYSA-N 0.000 title abstract 2
- ROBKVGDBQLURAF-UHFFFAOYSA-N 1,4-dihydroquinoline Chemical compound C1=CC=C2CC=CNC2=C1 ROBKVGDBQLURAF-UHFFFAOYSA-N 0.000 title abstract 2
- 102000012605 Cystic Fibrosis Transmembrane Conductance Regulator Human genes 0.000 title abstract 2
- 108010079245 Cystic Fibrosis Transmembrane Conductance Regulator Proteins 0.000 title abstract 2
- 201000003883 Cystic fibrosis Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 title 1
- 238000000034 method Methods 0.000 abstract 1
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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Abstract
Compuestos derivados de n-fenil-4-oxo-(1,4-dihidroquinolin o 1h-quinolin)-3-carboxamida, moduladores del regulador de conductancia transmembrana de fibrosis quística (cftr); composición farmacéutica; método de tratamiento; kit farmacéutico; proceso de preparación; y su uso para el tratamiento de fibrosis quística, entre otros.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10783008P | 2008-10-23 | 2008-10-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2011000919A1 true CL2011000919A1 (es) | 2012-01-06 |
Family
ID=42119997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2011000919A CL2011000919A1 (es) | 2008-10-23 | 2011-04-21 | Compuestos derivados de n-fenil-4-oxo-(1,4-dihidroquinolin o 1h-quinolin)-3-carboxamida, moduladores del regulador de conductancia transmembrana de fibrosis quistica (cftr); compuestos intermediarios; composicion farmaceutica; kit farmaceutico; proceso de preparacion; y uso para el tratamiento de fibrosis quistica, diabetes, entre otros. |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US8513282B2 (es) |
| EP (1) | EP2349263B1 (es) |
| JP (1) | JP5645833B2 (es) |
| KR (1) | KR20110074917A (es) |
| CN (1) | CN102227424B (es) |
| AR (1) | AR074060A1 (es) |
| AU (1) | AU2009308284B2 (es) |
| BR (1) | BRPI0919930A2 (es) |
| CA (1) | CA2741718A1 (es) |
| CL (1) | CL2011000919A1 (es) |
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