ATE473751T1 - Isolierung und transplantation von retinalen stammzellen - Google Patents
Isolierung und transplantation von retinalen stammzellenInfo
- Publication number
- ATE473751T1 ATE473751T1 AT01907195T AT01907195T ATE473751T1 AT E473751 T1 ATE473751 T1 AT E473751T1 AT 01907195 T AT01907195 T AT 01907195T AT 01907195 T AT01907195 T AT 01907195T AT E473751 T1 ATE473751 T1 AT E473751T1
- Authority
- AT
- Austria
- Prior art keywords
- transplantation
- isolation
- stem cells
- retinal stem
- vivo
- Prior art date
Links
- 238000002955 isolation Methods 0.000 title abstract 2
- 230000002207 retinal effect Effects 0.000 title abstract 2
- 210000000130 stem cell Anatomy 0.000 title abstract 2
- 238000002054 transplantation Methods 0.000 title abstract 2
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000010354 integration Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/135—Platelet-derived growth factor [PDGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Environmental Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18172300P | 2000-02-11 | 2000-02-11 | |
| PCT/US2001/004419 WO2001058460A1 (en) | 2000-02-11 | 2001-02-12 | Isolation and transplantation of retinal stem cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE473751T1 true ATE473751T1 (de) | 2010-07-15 |
Family
ID=22665510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01907195T ATE473751T1 (de) | 2000-02-11 | 2001-02-12 | Isolierung und transplantation von retinalen stammzellen |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7514259B2 (de) |
| EP (1) | EP1261357B1 (de) |
| JP (1) | JP2003521910A (de) |
| AT (1) | ATE473751T1 (de) |
| AU (2) | AU3499801A (de) |
| CA (1) | CA2399434C (de) |
| DE (1) | DE60142553D1 (de) |
| WO (1) | WO2001058460A1 (de) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7547674B2 (en) * | 2001-06-06 | 2009-06-16 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
| US20020061587A1 (en) | 2000-07-31 | 2002-05-23 | Piero Anversa | Methods and compositions for the repair and/or regeneration of damaged myocardium |
| US7862810B2 (en) | 2000-07-31 | 2011-01-04 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
| AU2003249227A1 (en) * | 2002-07-12 | 2004-02-02 | University Of Washington | Methods and systems for extended in vitro culture of neuronal cells |
| DE602004024529D1 (de) * | 2003-06-11 | 2010-01-21 | Japan Science & Tech Agency | Verfahren zur herstellung eines retinalen neurozyten aus einer von irisgewebe abgeleiteten stammzelle sowie mit dem verfahren hergestellter retinaler neurozyt |
| WO2005001080A2 (en) | 2003-06-27 | 2005-01-06 | Ethicon, Incorporated | Postpartum-derived cells for use in treatment of disease of the heart and circulatory system |
| WO2006071794A2 (en) | 2004-12-23 | 2006-07-06 | Ethicon Incorporated | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same |
| US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
| US8491883B2 (en) | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
| US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
| US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
| US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
| US8518390B2 (en) | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
| GB0328021D0 (en) | 2003-12-03 | 2004-01-07 | Inst Of Ophthalmology | Method |
| WO2006071778A2 (en) | 2004-12-23 | 2006-07-06 | Ethicon Incorporated | Treatment of parkinson's disease and related disorders using postpartum derived cells |
| WO2007070870A1 (en) | 2005-12-16 | 2007-06-21 | Ethicon, Inc. | Compositions and methods for inhibiting adverse immune response in histocompatibility-mismatched transplantation |
| JP5179376B2 (ja) | 2005-12-19 | 2013-04-10 | エシコン・インコーポレイテッド | ローラーボトルでの分娩後取り出し細胞の体外増殖 |
| US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
| WO2007130060A2 (en) | 2006-05-03 | 2007-11-15 | Schepens Eye Research | Isolation and therapeutic application of adult retinal stem cells collected from extra-retinal tissues |
| US9061017B2 (en) * | 2006-05-03 | 2015-06-23 | The Schepens Eye Research Institute, Inc. | Isolation and therapeutic application of adult retinal stem cells collected from extra-retinal tissues |
| EP2484308A1 (de) * | 2006-07-24 | 2012-08-08 | International Stem Cell Corporation | Synthetische Hornhaut aus Netzhautstammzellen |
| JP5323845B2 (ja) | 2007-10-05 | 2013-10-23 | エシコン・インコーポレイテッド | ヒト臍帯組織由来細胞を用いた腎組織の修復および再建 |
| US8236538B2 (en) | 2007-12-20 | 2012-08-07 | Advanced Technologies And Regenerative Medicine, Llc | Methods for sterilizing materials containing biologically active agents |
| US8481313B2 (en) | 2008-04-22 | 2013-07-09 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
| US20100098675A1 (en) * | 2008-05-30 | 2010-04-22 | Nikolai Tankovich | Methods for reducing the side effects of ophthalmic laser surgery |
| GB0822246D0 (en) * | 2008-12-05 | 2009-01-14 | Reneuron Ltd | Composition |
| CN102387807A (zh) | 2008-12-19 | 2012-03-21 | 先进科技及再生医学有限责任公司 | 肺部疾病和病症的治疗 |
| US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
| GB0902034D0 (en) | 2009-02-06 | 2009-03-11 | Reneuron Ltd | Method |
| SG174551A1 (en) | 2009-03-26 | 2011-10-28 | Ethicon Inc | Human umbilical cord tissue cells as therapy for alzheimer' s disease |
| CA2835215C (en) * | 2011-05-18 | 2023-10-10 | The Regents Of The University Of California | Non-immortal human retinal cell compositions, method for preparing them, and their use for treating retinal diseases |
| US8563304B2 (en) | 2011-06-14 | 2013-10-22 | The Schepens Eye Research Institute | Low oxygen culture conditions for maintaining retinal progenitor cell multipotency |
| AU2012358810B2 (en) | 2011-12-23 | 2018-03-15 | DePuy Synthes Products, Inc. | Detection of human umbilical cord tissue-derived cells |
| ES2700980T3 (es) | 2012-02-17 | 2019-02-20 | Schepens Eye Res Inst | Perfil fenotípico de células progenitoras de retina humana |
| GB201302468D0 (en) | 2013-02-12 | 2013-03-27 | Reneuron Ltd | Stem cell product |
| EP2833893B1 (de) | 2012-04-03 | 2018-08-29 | Reneuron Limited | Stammzellenmikropartikel |
| RU2494712C1 (ru) * | 2012-05-18 | 2013-10-10 | Федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения и социального развития Российской Федерации | Способ лечения атрофии зрительного нерва различной этиологии |
| SG11201500329WA (en) | 2012-07-19 | 2015-02-27 | Reneuron Ltd | Stem cell microparticles |
| US20160002597A1 (en) | 2013-02-12 | 2016-01-07 | Reneuron Limited | Method of producing microparticles |
| CN103409363B (zh) * | 2013-08-06 | 2015-01-21 | 中国人民解放军总医院 | 感光前体细胞与视网膜组织体外共培养方法 |
| GB201317887D0 (en) | 2013-10-09 | 2013-11-20 | Reneuron Ltd | Product |
| GB201317889D0 (en) | 2013-10-09 | 2013-11-20 | Reneuron Ltd | Product and use |
| EP3204021A4 (de) * | 2014-10-07 | 2018-03-07 | Nutech Medical, Inc. | Diagnosetest mit mesenchymalen stammzellen |
| CH711966A2 (it) * | 2015-12-23 | 2017-06-30 | Pinelli Roberto | Cellule staminali retinali. |
| WO2018220490A1 (en) * | 2017-06-02 | 2018-12-06 | Janssen Biotech, Inc. | Method of modulating müller glia cells |
| US12090252B2 (en) | 2017-09-14 | 2024-09-17 | Riken | Method for producing retinal tissues |
| WO2020069360A1 (en) * | 2018-09-27 | 2020-04-02 | The Regents Of The University Of California | Methods of human retinal progenitor cell isolation and culture |
| KR102196069B1 (ko) * | 2019-04-17 | 2020-12-29 | 경북대학교 산학협력단 | 망막신경절세포의 분리방법 및 그에 의해 분리된 세포의 용도 |
| GB201919021D0 (en) | 2019-12-20 | 2020-02-05 | Reneuron Ltd | Nucleic acid constructs for delivering polynucleotides into exosomes |
| GB202114441D0 (en) | 2021-10-08 | 2021-11-24 | Reneuron Ltd | Proteins and extracellular vesicles |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2636968B1 (fr) * | 1988-09-27 | 1992-01-03 | Inst Nat Sante Rech Med | Acide nucleique codant pour l'enzyme de conversion de l'angiotensine (eca) humaine, et ses applications, notamment pour le diagnostic in vitro de l'hypertension arterielle |
| WO1992010591A1 (en) * | 1990-12-14 | 1992-06-25 | Cell Genesys, Inc. | Chimeric chains for receptor-associated signal transduction pathways |
| US5851832A (en) * | 1991-07-08 | 1998-12-22 | Neurospheres, Ltd. | In vitro growth and proliferation of multipotent neural stem cells and their progeny |
| US6071889A (en) * | 1991-07-08 | 2000-06-06 | Neurospheres Holdings Ltd. | In vivo genetic modification of growth factor-responsive neural precursor cells |
| US5981165A (en) * | 1991-07-08 | 1999-11-09 | Neurospheres Holdings Ltd. | In vitro induction of dopaminergic cells |
| US5980885A (en) * | 1991-07-08 | 1999-11-09 | Neurospheres Holdings Ltd. | Growth factor-induced proliferation of neural precursor cells in vivo |
| US5750376A (en) | 1991-07-08 | 1998-05-12 | Neurospheres Holdings Ltd. | In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny |
| US5654183A (en) * | 1992-07-27 | 1997-08-05 | California Institute Of Technology | Genetically engineered mammalian neural crest stem cells |
| US5672499A (en) * | 1992-07-27 | 1997-09-30 | California Institute Of Technology | Immoralized neural crest stem cells and methods of making |
| US5849553A (en) * | 1992-07-27 | 1998-12-15 | California Institute Of Technology | Mammalian multipotent neural stem cells |
| NZ256154A (en) * | 1992-07-27 | 1997-02-24 | California Inst Of Techn | Production of mammalian multipotent neural stem cells, antibodies |
| WO1994009119A1 (en) | 1992-10-16 | 1994-04-28 | Neurospheres Ltd. | Remyelination using neural stem cells |
| KR950704476A (ko) | 1992-10-28 | 1995-11-20 | 브렌드 레이놀즈 | 생물학적 인자 및 신경 간세포(biological factors and neural stem cells) |
| FR2699191B1 (fr) * | 1992-12-16 | 1995-02-10 | Univ Paris Curie | Nouveaux vecteurs rétroviraux, lignées cellulaires les contenant, et leur utilisation dans le traitement des tumeurs. |
| FI953569A7 (fi) | 1993-01-29 | 1995-09-25 | Neurospheres Ltd | Neuraalisten kantasolujen geneettinen modifikaatio |
| US6033906A (en) * | 1993-07-26 | 2000-03-07 | California Institute Of Technology | Methods for differentiating neural stem cells to glial cells using neuregulins |
| CN1141058A (zh) | 1993-11-09 | 1997-01-22 | 纽罗斯菲里斯控股有限公司 | 中枢神经系统干细胞的原位修饰和处理 |
| US6001654A (en) * | 1994-01-28 | 1999-12-14 | California Institute Of Technology | Methods for differentiating neural stem cells to neurons or smooth muscle cells using TGT-β super family growth factors |
| US5935849A (en) * | 1994-07-20 | 1999-08-10 | Cytotherapeutics, Inc. | Methods and compositions of growth control for cells encapsulated within bioartificial organs |
| US5795790A (en) * | 1994-07-20 | 1998-08-18 | Cytotherapeutics, Inc. | Method for controlling proliferation and differentiation of cells encapsulated within bioartificial organs |
| ES2167461T3 (es) | 1994-09-23 | 2002-05-16 | Neurospheres Holdings Ltd | Modelos in vitro de funcion y disfuncion del sistema nervioso central. |
| FI971956L (fi) | 1994-11-14 | 1997-07-04 | Neurospheres Holdings Ltd | Hermosolujen lisääntymisen säännöstely |
| US5861283A (en) * | 1995-03-31 | 1999-01-19 | The University Of Medicine And Dentistry Of New Jersey | DNA encoding a limbic system-associated membrane protein |
| WO1997035605A1 (en) | 1996-03-26 | 1997-10-02 | Neurospheres Holdings Ltd. | Manipulation of mitotically active cells of the hippocampal region of the brain |
| US5753506A (en) * | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
| CA2216439A1 (en) * | 1996-09-25 | 1998-03-25 | Derek Van Der Kooy | Pharmaceuticals containing retinal stem cells |
| US5968829A (en) * | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
| US6093531A (en) * | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
| US6165783A (en) * | 1997-10-24 | 2000-12-26 | Neuro Spheres Holdings Ltd. | Erythropoietin-mediated neurogenesis |
| AU3964799A (en) * | 1998-04-24 | 1999-11-16 | University Of Nebraska Board Of Regents | Compositions and methods for the characterization and transplantation of mammalian retinal stem cells |
| US6171610B1 (en) * | 1998-04-24 | 2001-01-09 | University Of Massachusetts | Guided development and support of hydrogel-cell compositions |
| US5958767A (en) * | 1998-08-14 | 1999-09-28 | The Children's Medical Center Corp. | Engraftable human neural stem cells |
| US6184035B1 (en) * | 1998-11-18 | 2001-02-06 | California Institute Of Technology | Methods for isolation and activation of, and control of differentiation from, skeletal muscle stem or progenitor cells |
| WO2000047718A1 (en) | 1999-02-11 | 2000-08-17 | The Salk Institute For Biological Studies | Isolation of stem cells and methods of use thereof |
-
2001
- 2001-02-12 AU AU3499801A patent/AU3499801A/xx active Pending
- 2001-02-12 US US10/203,105 patent/US7514259B2/en not_active Expired - Fee Related
- 2001-02-12 AU AU2001234998A patent/AU2001234998B2/en not_active Expired
- 2001-02-12 JP JP2001557570A patent/JP2003521910A/ja active Pending
- 2001-02-12 DE DE60142553T patent/DE60142553D1/de not_active Expired - Lifetime
- 2001-02-12 EP EP01907195A patent/EP1261357B1/de not_active Expired - Lifetime
- 2001-02-12 AT AT01907195T patent/ATE473751T1/de not_active IP Right Cessation
- 2001-02-12 WO PCT/US2001/004419 patent/WO2001058460A1/en not_active Ceased
- 2001-02-12 CA CA2399434A patent/CA2399434C/en not_active Expired - Lifetime
-
2008
- 2008-11-06 US US12/266,116 patent/US20090104694A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2399434C (en) | 2010-10-19 |
| CA2399434A1 (en) | 2001-08-16 |
| AU3499801A (en) | 2001-08-20 |
| AU2001234998B2 (en) | 2006-06-08 |
| JP2003521910A (ja) | 2003-07-22 |
| US7514259B2 (en) | 2009-04-07 |
| EP1261357A1 (de) | 2002-12-04 |
| EP1261357B1 (de) | 2010-07-14 |
| US20090104694A1 (en) | 2009-04-23 |
| DE60142553D1 (de) | 2010-08-26 |
| WO2001058460A1 (en) | 2001-08-16 |
| US20030207450A1 (en) | 2003-11-06 |
| EP1261357A4 (de) | 2004-05-19 |
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