ATE473983T1 - Ein peroxyderivat enthaltende duale moleküle, deren synthese und deren therapeutische anwendungen - Google Patents

Ein peroxyderivat enthaltende duale moleküle, deren synthese und deren therapeutische anwendungen

Info

Publication number
ATE473983T1
ATE473983T1 AT04805417T AT04805417T ATE473983T1 AT E473983 T1 ATE473983 T1 AT E473983T1 AT 04805417 T AT04805417 T AT 04805417T AT 04805417 T AT04805417 T AT 04805417T AT E473983 T1 ATE473983 T1 AT E473983T1
Authority
AT
Austria
Prior art keywords
synthesis
therapeutic applications
molecules containing
dual molecules
peroxy
Prior art date
Application number
AT04805417T
Other languages
English (en)
Inventor
Jerome Cazelles
Frederic Cosledan
Bernard Meunier
Alain Pellet
Original Assignee
Centre Nat Rech Scient
Palumed Sa
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Palumed Sa, Sanofi Aventis filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE473983T1 publication Critical patent/ATE473983T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT04805417T 2003-11-14 2004-11-09 Ein peroxyderivat enthaltende duale moleküle, deren synthese und deren therapeutische anwendungen ATE473983T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0313371A FR2862304A1 (fr) 2003-11-14 2003-11-14 Molecules duales racemiques ou achirales contenant un derive peroxydique, leur synthese et leurs applications therapeutiques
PCT/FR2004/002874 WO2005049619A1 (fr) 2003-11-14 2004-11-09 Molecules duales contenant un derive peroxydique, leur synthese et leurs applications therapeutiques

Publications (1)

Publication Number Publication Date
ATE473983T1 true ATE473983T1 (de) 2010-07-15

Family

ID=34508480

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04805417T ATE473983T1 (de) 2003-11-14 2004-11-09 Ein peroxyderivat enthaltende duale moleküle, deren synthese und deren therapeutische anwendungen

Country Status (25)

Country Link
US (1) US7947701B2 (de)
EP (1) EP1687312B1 (de)
JP (1) JP2007511489A (de)
CN (1) CN100448878C (de)
AP (1) AP2006003626A0 (de)
AR (1) AR046449A1 (de)
AT (1) ATE473983T1 (de)
AU (1) AU2004291374A1 (de)
BR (1) BRPI0416593A (de)
CA (1) CA2545491A1 (de)
DE (1) DE602004028149D1 (de)
DK (1) DK1687312T3 (de)
ES (1) ES2348624T3 (de)
FR (1) FR2862304A1 (de)
HR (1) HRP20100557T1 (de)
IL (1) IL175589A0 (de)
MX (1) MXPA06005409A (de)
NO (1) NO20062740L (de)
NZ (1) NZ547805A (de)
PL (1) PL1687312T3 (de)
PT (1) PT1687312E (de)
SI (1) SI1687312T1 (de)
TW (1) TW200530249A (de)
WO (1) WO2005049619A1 (de)
ZA (1) ZA200604247B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2902100A1 (fr) * 2006-06-13 2007-12-14 Sanofi Aventis Sa Molecules duales contenant un derive peroxydique, leur synthese et leurs applications en therapeutique
FR2924343A1 (fr) * 2007-12-04 2009-06-05 Palumed Sa Nouvelles utilisations therapeutiques de molecules duales contenant un derive peroxydique.
US20170000784A1 (en) * 2013-12-08 2017-01-05 Van Andel Research Institute Autophagy Inhibitors
WO2015123595A1 (en) 2014-02-14 2015-08-20 The Regents Of The University Of California Cyclic peroxides as prodrugs for selective delivery of agents
TWI903299B (zh) 2018-03-08 2025-11-01 美商英塞特公司 作為PI3K-γ抑制劑之胺基吡嗪二醇化合物
WO2020010003A1 (en) 2018-07-02 2020-01-09 Incyte Corporation AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2807433B1 (fr) * 2000-04-06 2002-09-20 Centre Nat Rech Scient Molecules duales contenant un derives peroxydique, leur synthese et leurs applications therapeutiques
US6486199B1 (en) * 2001-06-21 2002-11-26 Medicines For Malaria Venture Mmv International Centre Cointrin Spiro and dispiro 1,2,4-trioxolane antimalarials

Also Published As

Publication number Publication date
SI1687312T1 (sl) 2010-11-30
ES2348624T3 (es) 2010-12-09
DE602004028149D1 (de) 2010-08-26
NO20062740L (no) 2006-08-11
CN1910189A (zh) 2007-02-07
EP1687312A1 (de) 2006-08-09
FR2862304A1 (fr) 2005-05-20
PT1687312E (pt) 2010-10-18
CA2545491A1 (fr) 2005-06-02
DK1687312T3 (da) 2010-11-08
PL1687312T3 (pl) 2011-07-29
BRPI0416593A (pt) 2007-01-30
AU2004291374A1 (en) 2005-06-02
MXPA06005409A (es) 2007-11-22
TW200530249A (en) 2005-09-16
ZA200604247B (en) 2008-05-28
IL175589A0 (en) 2006-09-05
EP1687312B1 (de) 2010-07-14
AR046449A1 (es) 2005-12-07
NZ547805A (en) 2010-05-28
US20070021423A1 (en) 2007-01-25
US7947701B2 (en) 2011-05-24
WO2005049619A1 (fr) 2005-06-02
AP2006003626A0 (en) 2006-06-30
JP2007511489A (ja) 2007-05-10
HRP20100557T1 (hr) 2011-03-31
CN100448878C (zh) 2009-01-07

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