NO20062740L - Duale molekyler inneholdende peroksyderivat, syntese derav og terapeutiske anvendelser derav - Google Patents
Duale molekyler inneholdende peroksyderivat, syntese derav og terapeutiske anvendelser deravInfo
- Publication number
- NO20062740L NO20062740L NO20062740A NO20062740A NO20062740L NO 20062740 L NO20062740 L NO 20062740L NO 20062740 A NO20062740 A NO 20062740A NO 20062740 A NO20062740 A NO 20062740A NO 20062740 L NO20062740 L NO 20062740L
- Authority
- NO
- Norway
- Prior art keywords
- residue
- synthesis
- dual molecules
- therapeutic applications
- molecules containing
- Prior art date
Links
- 230000009977 dual effect Effects 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 title 1
- 150000002978 peroxides Chemical class 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 4
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 239000003430 antimalarial agent Substances 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- AEOCXXJPGCBFJA-UHFFFAOYSA-N ethionamide Chemical compound CCC1=CC(C(N)=S)=CC=N1 AEOCXXJPGCBFJA-UHFFFAOYSA-N 0.000 abstract 2
- 229940124530 sulfonamide Drugs 0.000 abstract 2
- 150000003456 sulfonamides Chemical class 0.000 abstract 2
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 abstract 2
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 2
- 125000002813 thiocarbonyl group Chemical group *C(*)=S 0.000 abstract 2
- 150000003568 thioethers Chemical group 0.000 abstract 2
- 230000000078 anti-malarial effect Effects 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- -1 cyclic peroxide Chemical class 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000003367 polycyclic group Chemical group 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0313371A FR2862304A1 (fr) | 2003-11-14 | 2003-11-14 | Molecules duales racemiques ou achirales contenant un derive peroxydique, leur synthese et leurs applications therapeutiques |
| PCT/FR2004/002874 WO2005049619A1 (fr) | 2003-11-14 | 2004-11-09 | Molecules duales contenant un derive peroxydique, leur synthese et leurs applications therapeutiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20062740L true NO20062740L (no) | 2006-08-11 |
Family
ID=34508480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20062740A NO20062740L (no) | 2003-11-14 | 2006-06-13 | Duale molekyler inneholdende peroksyderivat, syntese derav og terapeutiske anvendelser derav |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7947701B2 (de) |
| EP (1) | EP1687312B1 (de) |
| JP (1) | JP2007511489A (de) |
| CN (1) | CN100448878C (de) |
| AP (1) | AP2006003626A0 (de) |
| AR (1) | AR046449A1 (de) |
| AT (1) | ATE473983T1 (de) |
| AU (1) | AU2004291374A1 (de) |
| BR (1) | BRPI0416593A (de) |
| CA (1) | CA2545491A1 (de) |
| DE (1) | DE602004028149D1 (de) |
| DK (1) | DK1687312T3 (de) |
| ES (1) | ES2348624T3 (de) |
| FR (1) | FR2862304A1 (de) |
| HR (1) | HRP20100557T1 (de) |
| IL (1) | IL175589A0 (de) |
| MX (1) | MXPA06005409A (de) |
| NO (1) | NO20062740L (de) |
| NZ (1) | NZ547805A (de) |
| PL (1) | PL1687312T3 (de) |
| PT (1) | PT1687312E (de) |
| SI (1) | SI1687312T1 (de) |
| TW (1) | TW200530249A (de) |
| WO (1) | WO2005049619A1 (de) |
| ZA (1) | ZA200604247B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2902100A1 (fr) * | 2006-06-13 | 2007-12-14 | Sanofi Aventis Sa | Molecules duales contenant un derive peroxydique, leur synthese et leurs applications en therapeutique |
| FR2924343A1 (fr) * | 2007-12-04 | 2009-06-05 | Palumed Sa | Nouvelles utilisations therapeutiques de molecules duales contenant un derive peroxydique. |
| US20170000784A1 (en) * | 2013-12-08 | 2017-01-05 | Van Andel Research Institute | Autophagy Inhibitors |
| WO2015123595A1 (en) | 2014-02-14 | 2015-08-20 | The Regents Of The University Of California | Cyclic peroxides as prodrugs for selective delivery of agents |
| TWI903299B (zh) | 2018-03-08 | 2025-11-01 | 美商英塞特公司 | 作為PI3K-γ抑制劑之胺基吡嗪二醇化合物 |
| WO2020010003A1 (en) | 2018-07-02 | 2020-01-09 | Incyte Corporation | AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2807433B1 (fr) * | 2000-04-06 | 2002-09-20 | Centre Nat Rech Scient | Molecules duales contenant un derives peroxydique, leur synthese et leurs applications therapeutiques |
| US6486199B1 (en) * | 2001-06-21 | 2002-11-26 | Medicines For Malaria Venture Mmv International Centre Cointrin | Spiro and dispiro 1,2,4-trioxolane antimalarials |
-
2003
- 2003-11-14 FR FR0313371A patent/FR2862304A1/fr not_active Withdrawn
-
2004
- 2004-11-09 ZA ZA200604247A patent/ZA200604247B/en unknown
- 2004-11-09 AT AT04805417T patent/ATE473983T1/de active
- 2004-11-09 PT PT04805417T patent/PT1687312E/pt unknown
- 2004-11-09 MX MXPA06005409A patent/MXPA06005409A/es not_active Application Discontinuation
- 2004-11-09 SI SI200431519T patent/SI1687312T1/sl unknown
- 2004-11-09 HR HR20100557T patent/HRP20100557T1/hr unknown
- 2004-11-09 NZ NZ547805A patent/NZ547805A/en unknown
- 2004-11-09 AP AP2006003626A patent/AP2006003626A0/xx unknown
- 2004-11-09 DE DE602004028149T patent/DE602004028149D1/de not_active Expired - Lifetime
- 2004-11-09 CA CA002545491A patent/CA2545491A1/fr not_active Abandoned
- 2004-11-09 EP EP04805417A patent/EP1687312B1/de not_active Expired - Lifetime
- 2004-11-09 WO PCT/FR2004/002874 patent/WO2005049619A1/fr not_active Ceased
- 2004-11-09 DK DK04805417.5T patent/DK1687312T3/da active
- 2004-11-09 CN CNB2004800372615A patent/CN100448878C/zh not_active Expired - Fee Related
- 2004-11-09 ES ES04805417T patent/ES2348624T3/es not_active Expired - Lifetime
- 2004-11-09 AU AU2004291374A patent/AU2004291374A1/en not_active Abandoned
- 2004-11-09 PL PL04805417T patent/PL1687312T3/pl unknown
- 2004-11-09 BR BRPI0416593-4A patent/BRPI0416593A/pt not_active IP Right Cessation
- 2004-11-09 JP JP2006538893A patent/JP2007511489A/ja active Pending
- 2004-11-12 TW TW093134762A patent/TW200530249A/zh unknown
- 2004-11-12 AR ARP040104170A patent/AR046449A1/es unknown
-
2006
- 2006-05-11 IL IL175589A patent/IL175589A0/en unknown
- 2006-05-12 US US11/433,890 patent/US7947701B2/en not_active Expired - Fee Related
- 2006-06-13 NO NO20062740A patent/NO20062740L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SI1687312T1 (sl) | 2010-11-30 |
| ES2348624T3 (es) | 2010-12-09 |
| DE602004028149D1 (de) | 2010-08-26 |
| CN1910189A (zh) | 2007-02-07 |
| EP1687312A1 (de) | 2006-08-09 |
| FR2862304A1 (fr) | 2005-05-20 |
| PT1687312E (pt) | 2010-10-18 |
| CA2545491A1 (fr) | 2005-06-02 |
| DK1687312T3 (da) | 2010-11-08 |
| PL1687312T3 (pl) | 2011-07-29 |
| BRPI0416593A (pt) | 2007-01-30 |
| AU2004291374A1 (en) | 2005-06-02 |
| MXPA06005409A (es) | 2007-11-22 |
| TW200530249A (en) | 2005-09-16 |
| ZA200604247B (en) | 2008-05-28 |
| ATE473983T1 (de) | 2010-07-15 |
| IL175589A0 (en) | 2006-09-05 |
| EP1687312B1 (de) | 2010-07-14 |
| AR046449A1 (es) | 2005-12-07 |
| NZ547805A (en) | 2010-05-28 |
| US20070021423A1 (en) | 2007-01-25 |
| US7947701B2 (en) | 2011-05-24 |
| WO2005049619A1 (fr) | 2005-06-02 |
| AP2006003626A0 (en) | 2006-06-30 |
| JP2007511489A (ja) | 2007-05-10 |
| HRP20100557T1 (hr) | 2011-03-31 |
| CN100448878C (zh) | 2009-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |