ATE475419T1 - Verfahren zur zubereitung von lansoprazol - Google Patents

Verfahren zur zubereitung von lansoprazol

Info

Publication number
ATE475419T1
ATE475419T1 AT06706233T AT06706233T ATE475419T1 AT E475419 T1 ATE475419 T1 AT E475419T1 AT 06706233 T AT06706233 T AT 06706233T AT 06706233 T AT06706233 T AT 06706233T AT E475419 T1 ATE475419 T1 AT E475419T1
Authority
AT
Austria
Prior art keywords
lansoprazole
preparing
preparing lansoprazole
directed
pharmaceutical composition
Prior art date
Application number
AT06706233T
Other languages
English (en)
Inventor
Berta Kotar-Jordan
Franc Vrecer
Zakelj Mojca Segula
Gregor Ritlop
Original Assignee
Krka Tovarna Zdravil D D Novo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krka Tovarna Zdravil D D Novo filed Critical Krka Tovarna Zdravil D D Novo
Application granted granted Critical
Publication of ATE475419T1 publication Critical patent/ATE475419T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicinal Preparation (AREA)
AT06706233T 2005-01-14 2006-01-13 Verfahren zur zubereitung von lansoprazol ATE475419T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05000663A EP1681056A1 (de) 2005-01-14 2005-01-14 Verfahren zur Herstellung von Lansoprazol
US11/269,211 US7662968B2 (en) 2005-01-14 2005-11-08 Process for preparing lansoprazole
PCT/EP2006/000285 WO2006074952A1 (en) 2005-01-14 2006-01-13 Process for preparing lansoprazole

Publications (1)

Publication Number Publication Date
ATE475419T1 true ATE475419T1 (de) 2010-08-15

Family

ID=34933288

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06706233T ATE475419T1 (de) 2005-01-14 2006-01-13 Verfahren zur zubereitung von lansoprazol

Country Status (14)

Country Link
US (1) US7662968B2 (de)
EP (3) EP1681056A1 (de)
CN (2) CN101824028A (de)
AT (1) ATE475419T1 (de)
AU (1) AU2006205818A1 (de)
CA (1) CA2594821A1 (de)
DE (1) DE602006015771D1 (de)
EA (1) EA015043B1 (de)
NO (1) NO20074086L (de)
NZ (1) NZ556706A (de)
SI (2) SI2308492T1 (de)
UA (1) UA90293C2 (de)
WO (1) WO2006074952A1 (de)
ZA (1) ZA200706691B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5173191B2 (ja) * 2004-09-13 2013-03-27 武田薬品工業株式会社 酸化化合物の製造方法及び製造装置
US8129536B2 (en) 2006-09-22 2012-03-06 Orchid Chemicals & Pharmaceuticals Limited Method for the purification of lansoprazole
ITMI20062481A1 (it) * 2006-12-22 2008-06-23 Recordati Chem Pharm Processo per la preparazione di lansoprazolo forma i microcristallino
EP2152244B1 (de) * 2007-04-26 2015-12-02 Technion Research & Development Foundation Ltd. Orale verabreichung von proteinen und peptiden
SI22806A (sl) * 2008-06-23 2009-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove kristalinične oblike natrijevega rabeprazola
WO2011063150A2 (en) * 2009-11-20 2011-05-26 Handa Pharmaceuticals, Llc Oral formulation for dexlansoprazole
US20120039999A1 (en) * 2010-08-11 2012-02-16 Ashish Chatterji Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
US20120040008A1 (en) * 2010-08-11 2012-02-16 Ashish Chatterji Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
CN102180865B (zh) * 2011-03-17 2013-01-16 浙江工业大学 一种兰索拉唑的合成方法
CN102558154B (zh) * 2012-02-24 2014-01-08 海南锦瑞制药股份有限公司 一种兰索拉唑结晶化合物及其肠溶胶囊、及制备方法
CN102838537B (zh) * 2012-09-18 2014-04-09 寿光富康制药有限公司 一种兰索拉唑中间体的制备方法
CN103539728A (zh) * 2013-10-14 2014-01-29 安徽国星生物化学有限公司 一种拉唑类药物中间体氯甲基吡啶衍生物的合成方法
CN103539729A (zh) * 2013-10-14 2014-01-29 安徽国星生物化学有限公司 一种氯甲基吡啶衍生物的工业化生产方法
CN103664750A (zh) * 2013-12-09 2014-03-26 惠州市莱佛士制药技术有限公司 一种拉唑氯代物的合成方法
CN104083330A (zh) * 2014-02-21 2014-10-08 杭州长典医药科技有限公司 兰索拉唑钠特种超细粉体冻干制剂及其制备方法
CN104447696B (zh) * 2014-11-19 2016-08-17 上海泰坦科技股份有限公司 兰索拉唑的合成工艺
CN104557693B (zh) * 2015-01-16 2017-01-04 江苏中邦制药有限公司 一种3,5-二甲基-4-硝基吡啶-n-氧化物的合成方法
CN104592107B (zh) * 2015-01-16 2017-01-11 江苏中邦制药有限公司 一种2,3-二甲基-4-硝基吡啶-n-氧化物的合成方法
CN104817492B (zh) * 2015-05-22 2018-05-18 抚州三和医药化工有限公司 兰索拉唑中间体2-羟甲基-3-甲基-4-(2,2,2-三氟乙氧基）吡啶的分离纯化方法
CN106928191B (zh) * 2015-12-30 2019-09-03 河南康达制药有限公司 一种兰索拉唑的制备工艺
CN106543146A (zh) * 2016-11-10 2017-03-29 石家庄市度智医药科技有限公司 一种右兰索拉唑的制备方法
CN106749186B (zh) * 2016-12-29 2019-03-05 南京海融制药有限公司 一种右兰索拉唑钠的新晶型及其制备方法
CN106619520B (zh) * 2016-12-29 2019-08-06 南京海融制药有限公司 一种右兰索拉唑钠的干混悬剂及其制备方法
CN106727381B (zh) * 2016-12-29 2020-07-07 南京海融制药有限公司 一种右兰索拉唑钠的口崩片及其制备方法
CN108947967B (zh) * 2018-08-24 2020-10-30 迪嘉药业集团有限公司 一种兰索拉唑的制备方法
CN112533608B (zh) * 2018-09-03 2022-09-20 正大天晴药业集团股份有限公司 包含1,3,5-三嗪衍生物或其盐的固体药物组合物
CN114163419A (zh) * 2021-12-24 2022-03-11 辰欣药业股份有限公司 一种兰索拉唑的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
DK171989B1 (da) * 1987-08-04 1997-09-08 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler
TW385306B (en) * 1996-11-14 2000-03-21 Takeda Chemical Industries Ltd Method for producing crystals of benzimidazole derivatives
WO1999002521A1 (en) * 1997-07-11 1999-01-21 Eisai Co., Ltd. Processes for the preparation of pyridine derivatives
KR100883477B1 (ko) * 1999-05-27 2009-02-16 아쿠스피어 인코포레이티드. 다공성 약물 매트릭스의 약제 조성물
PL333847A1 (en) * 1999-06-18 2001-01-02 Inst Farmaceutyczny Crystalline forms of lansoprozole and method of obtaining lansoprazole in pharmacologically advanthageous crystalline form
CA2436825C (en) * 2000-12-01 2011-01-18 Takeda Chemical Industries, Ltd. Process for the crystallization of (r)- or (s)-lansoprazole
SK10792003A3 (sk) * 2001-02-02 2004-07-07 Teva Pharmaceutical Industries Ltd. Spôsob výroby substituovaných 2-(2-pyridylmetyl) sulfinyl -1H-benzimidazolov
KR100433735B1 (ko) * 2001-06-27 2004-06-04 주식회사 씨트리 결정형 ⅰ을 갖는 란소프라졸의 제조방법
ATE321758T1 (de) 2001-07-16 2006-04-15 Janssen Pharmaceutica Nv Verbessertes verfahren zur herstellung von verbindungen des benzimidazoltyps
CA2480352A1 (en) * 2002-03-27 2003-10-09 Teva Pharmaceutical Industries Ltd. Lansoprazole polymorphs and processes for preparation thereof
JP4115751B2 (ja) * 2002-05-31 2008-07-09 株式会社パーマケム・アジア 微水ベンズイミダゾール系化合物の製法
WO2004011455A1 (en) * 2002-07-26 2004-02-05 Teva Pharmaceutical Industries Ltd. Preparation of lansoprazole and related compounds

Also Published As

Publication number Publication date
EA200701461A1 (ru) 2008-02-28
US7662968B2 (en) 2010-02-16
EP1681056A1 (de) 2006-07-19
EP1838314B1 (de) 2010-07-28
EP2308492A1 (de) 2011-04-13
EP1838314A1 (de) 2007-10-03
SI1838314T1 (sl) 2010-11-30
EP2308492B1 (de) 2016-09-14
WO2006074952A1 (en) 2006-07-20
AU2006205818A1 (en) 2006-07-20
ZA200706691B (en) 2008-09-25
CN101824028A (zh) 2010-09-08
NZ556706A (en) 2009-11-27
EA015043B1 (ru) 2011-04-29
CA2594821A1 (en) 2006-07-20
US20070259049A1 (en) 2007-11-08
CN101137371B (zh) 2011-05-25
UA90293C2 (en) 2010-04-26
CN101137371A (zh) 2008-03-05
DE602006015771D1 (de) 2010-09-09
SI2308492T1 (sl) 2017-02-28
NO20074086L (no) 2007-10-10

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