ATE475421T1 - Pyrazoloä4,3-düpyrimidines, verfahren zur ihre herstellung und deren verwendung - Google Patents

Pyrazoloä4,3-düpyrimidines, verfahren zur ihre herstellung und deren verwendung

Info

Publication number
ATE475421T1
ATE475421T1 AT03010184T AT03010184T ATE475421T1 AT E475421 T1 ATE475421 T1 AT E475421T1 AT 03010184 T AT03010184 T AT 03010184T AT 03010184 T AT03010184 T AT 03010184T AT E475421 T1 ATE475421 T1 AT E475421T1
Authority
AT
Austria
Prior art keywords
substituted
alkyl
unsubstituted
cycloalkyl
arylalkyl
Prior art date
Application number
AT03010184T
Other languages
English (en)
Inventor
Daniela Moravcova
Libor Havlicek
Vladimir Krystof
Rene Lenobel
Pavla Binarova
Petra Mlejnek
Borek Vojtesek
Stjepan Uldrijan
Thomas Schmuelling
Miroslav Strnad
Original Assignee
Ustav Ex Botan Akademie Ved Ce
Univ Palackeho
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ustav Ex Botan Akademie Ved Ce, Univ Palackeho filed Critical Ustav Ex Botan Akademie Ved Ce
Application granted granted Critical
Publication of ATE475421T1 publication Critical patent/ATE475421T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03010184T 2003-05-06 2003-05-06 Pyrazoloä4,3-düpyrimidines, verfahren zur ihre herstellung und deren verwendung ATE475421T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03010184A EP1475094B8 (de) 2003-05-06 2003-05-06 Pyrazolo[4,3-D]pyrimidines, verfahren zur ihre herstellung und deren verwendung

Publications (1)

Publication Number Publication Date
ATE475421T1 true ATE475421T1 (de) 2010-08-15

Family

ID=32981816

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03010184T ATE475421T1 (de) 2003-05-06 2003-05-06 Pyrazoloä4,3-düpyrimidines, verfahren zur ihre herstellung und deren verwendung

Country Status (8)

Country Link
US (1) US20070167466A1 (de)
EP (1) EP1475094B8 (de)
AT (1) ATE475421T1 (de)
CA (1) CA2524344C (de)
DE (1) DE60333546D1 (de)
DK (1) DK1475094T3 (de)
ES (1) ES2351624T3 (de)
WO (1) WO2004098608A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102558155A (zh) 2003-01-14 2012-07-11 阿伦纳药品公司 作为代谢调节剂的芳基和杂芳基衍生物及其所涉及的疾病如糖尿病和高血糖症的预防和治疗
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
TWI335328B (en) * 2003-07-14 2011-01-01 Arena Pharm Inc Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related hereto
KR101415503B1 (ko) 2003-07-17 2014-07-04 플렉시콘, 인코퍼레이티드 Ｐｐａｒ 활성 화합물
MY148521A (en) 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
US7932257B2 (en) * 2005-07-22 2011-04-26 Sunesis Pharmaceuticals, Inc. Substituted pyrazolo[4,3-d]pyrimidines as aurora kinase inhibitors
ES2564826T3 (es) * 2007-06-21 2016-03-29 Neuronascent, Inc. Métodos y composiciones para estimular neurogénesis e inhibir degeneración neuronal utilizando isotiazolopirimidinonas
KR101483215B1 (ko) * 2010-01-29 2015-01-16 한미약품 주식회사 단백질 키나아제 저해활성을 갖는 비시클릭 헤테로아릴 유도체
MX2013003184A (es) 2010-09-22 2013-06-07 Arena Pharm Inc Moduladores del receptor gpr119 y el tratamiento de transtornos relacionados con el mismo.
WO2014126580A1 (en) * 2013-02-15 2014-08-21 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
AU2016205361C1 (en) 2015-01-06 2021-04-08 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
CZ307147B6 (cs) * 2015-05-14 2018-02-07 Ústav experimentální botaniky AV ČR, v. v. i. 5-Substituované 7-[4-(2-pyridyl)fenylmethylamino]-3-isopropylpyrazolo[4,3-d]pyrimidiny, jejich použití jako léčiva, a farmaceutické přípravky
PL3310760T3 (pl) 2015-06-22 2023-03-06 Arena Pharmaceuticals, Inc. Krystaliczna sól L-argininy kwasu (R)-2-(7-(4-cyklopentylo-3-(trifluorometylo)benzyloksy)- 1,2,3,4-tetrahydrocyklo-penta[b]indol-3-ilo)octowego do zastosowania w zaburzeniach związanych z receptorem S1P1
AU2019280822A1 (en) 2018-06-06 2021-01-07 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
CN115554303B (zh) * 2021-09-18 2024-07-09 上海科技大学 一种三环类化合物、其制备方法及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1530747A (en) * 1922-05-20 1925-03-24 Frank B Wyatt Motion-picture machine
GB1530747A (en) * 1976-04-05 1978-11-01 Massachusetts Inst Technology Pharmaceutical composition
US4282361A (en) * 1978-03-16 1981-08-04 Massachusetts Institute Of Technology Synthesis for 7-alkylamino-3-methylpyrazolo [4,3-d]pyrimidines
CZ27399A3 (cs) * 1999-01-26 2000-08-16 Ústav Experimentální Botaniky Av Čr Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
AU7323000A (en) * 1999-08-26 2001-04-10 Plant Research International B.V. Conditional inhibition of vegetative propagation
DE10060388A1 (de) * 2000-12-05 2002-06-06 Merck Patent Gmbh Verwendung von Pyrazolo [4,3-d]pyrimidinen

Also Published As

Publication number Publication date
DE60333546D1 (de) 2010-09-09
WO2004098608A1 (en) 2004-11-18
DK1475094T3 (da) 2010-11-22
EP1475094A1 (de) 2004-11-10
ES2351624T3 (es) 2011-02-08
US20070167466A1 (en) 2007-07-19
CA2524344A1 (en) 2004-11-18
EP1475094B1 (de) 2010-07-28
EP1475094B8 (de) 2011-01-12
CA2524344C (en) 2012-03-13

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