ATE477810T1 - Stabilisierte albumin-zubereitungen - Google Patents

Stabilisierte albumin-zubereitungen

Info

Publication number: ATE477810T1
Authority: AT; Austria
Prior art keywords: albumin; solution; preparation; preparations; stabilized
Prior art date: 2002-02-28

Application number

AT03743064T

Other languages

English (en)

Inventor

Masaki Otagiri

Toshiya Kai

Makoto Sato

Original Assignee

Nipro Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-02-28

Filing date

2003-02-28

Publication date

2010-09-15

2003-02-28 Application filed by Nipro Corp filed Critical Nipro Corp

2010-09-15 Application granted granted Critical

2010-09-15 Publication of ATE477810T1 publication Critical patent/ATE477810T1/de

Links

102000009027 Albumins Human genes 0.000 title abstract 5
108010088751 Albumins Proteins 0.000 title abstract 5
238000002360 preparation method Methods 0.000 title abstract 5
239000000203 mixture Substances 0.000 abstract 2
239000000243 solution Substances 0.000 abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
241000700605 Viruses Species 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
239000000872 buffer Substances 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
239000003978 infusion fluid Substances 0.000 abstract 1
229940102223 injectable solution Drugs 0.000 abstract 1
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1
150000004667 medium chain fatty acids Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000007911 parenteral administration Methods 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
239000008363 phosphate buffer Substances 0.000 abstract 1
239000002504 physiological saline solution Substances 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000006641 stabilisation Effects 0.000 abstract 1
238000011105 stabilization Methods 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Gastroenterology & Hepatology (AREA)
Dermatology (AREA)
Hematology (AREA)
Zoology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT03743064T 2002-02-28 2003-02-28 Stabilisierte albumin-zubereitungen ATE477810T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2002053337		2002-02-28
PCT/JP2003/002320 WO2003072123A1 (fr)	2002-02-28	2003-02-28	Preparations d'albumine stabilisees

Publications (1)

Publication Number	Publication Date
ATE477810T1 true ATE477810T1 (de)	2010-09-15

Family

ID=27764357

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03743064T ATE477810T1 (de)	2002-02-28	2003-02-28	Stabilisierte albumin-zubereitungen

Country Status (9)

Country	Link
US (1)	US7351800B2 (de)
EP (1)	EP1479393B1 (de)
JP (1)	JP4259324B2 (de)
CN (1)	CN1330370C (de)
AT (1)	ATE477810T1 (de)
AU (1)	AU2003211474A1 (de)
CA (1)	CA2477557C (de)
DE (1)	DE60333821D1 (de)
WO (1)	WO2003072123A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7658938B2 (en)	1999-02-22	2010-02-09	Merrion Reasearch III Limited	Solid oral dosage form containing an enhancer
BRPI0710503A2 (pt)	2006-04-07	2011-08-16	Merrion Res Iii Ltd	uso de uma composição farmacêutica, composição farmacêutica, e, forma de dosagem oral
EP2033615B1 (de) *	2006-06-28	2017-05-10	Fujimori Kogyo Co., Ltd.	Flüssigkeitsbehälter
JP4935242B2 (ja) *	2006-08-24	2012-05-23	ニプロ株式会社	脂肪酸を含有するｓ−ニトロソタンパク質とその製法
US20090280169A1 (en) *	2008-05-07	2009-11-12	Merrion Research Iii Limited	Compositions of peptides and processes of preparation thereof
US9089484B2 (en)	2010-03-26	2015-07-28	Merrion Research Iii Limited	Pharmaceutical compositions of selective factor Xa inhibitors for oral administration
EP2661273A4 (de)	2011-01-07	2014-06-04	Merrion Res Iii Ltd	Pharmazeutische zusammensetzungen aus eisen zur oralen verabreichung
EP2719704B1 (de) *	2011-04-08	2016-07-20	Universidad De Costa Rica	Verfahren zur herstellung injizierbarerformulierungen aus blutderiviertem proteinmaterial und anhand dieses verfahrens hergestellte materialien
AU2013205138B2 (en) *	2012-08-09	2015-06-25	Grifols, S.A.	Caprylate Viral Deactivation
EP2931332B1 (de) *	2012-12-14	2021-10-06	Gambro Lundia AB	Reinigung von biologischen flüssigkeiten
JP7211704B2 (ja)	2015-01-29	2023-01-24	ノヴォノルディスクアー／エス	Ｇｌｐ－１アゴニスト及び腸溶コーティングを含む錠剤
CN106106739A (zh) *	2016-06-15	2016-11-16	广州嘉德乐生化科技有限公司	含有双乙酰酒石酸单双甘油酯的稳定剂组合物及其用途
WO2018115953A1 (en) *	2016-12-21	2018-06-28	Prometic Pharma Smt Limited	Methods and compositions for preventing or minimizing epithelial-mesenchymal transition
US12629445B2 (en)	2020-03-20	2026-05-19	Bard Peripheral Vascular, Inc.	Reactive hydrogel forming formulations and related methods, including methods of preparation
US12161777B2 (en)	2020-07-02	2024-12-10	Davol Inc.	Flowable hemostatic suspension
US11739166B2 (en)	2020-07-02	2023-08-29	Davol Inc.	Reactive polysaccharide-based hemostatic agent
WO2022146917A1 (en)	2020-12-28	2022-07-07	Davol Inc.	Reactive dry powdered hemostatic materials comprising a protein and a multifunctionalized modified polyethylene glycol based crosslinking agent

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5892619A (ja) *	1981-11-28	1983-06-02	Sunstar Inc	インタ−フエロンを安定に配合した組成物
JPS60215631A (ja) *	1984-04-09	1985-10-29	Takeda Chem Ind Ltd	インタ−ロイキン−２組成物
JP2799483B2 (ja) *	1988-03-09	1998-09-17	大塚製薬株式会社	インターロイキン−１β組成物の安定化方法
JPH01246226A (ja) *	1988-03-28	1989-10-02	Sumitomo Pharmaceut Co Ltd	安定な修飾アスパラギナーゼ含有組成物
US5277818A (en) *	1988-10-31	1994-01-11	The Green Cross Corporation	Albumin preparation and process for preparing the same
EP0401379B1 (de) *	1988-12-06	1994-06-15	Otsuka Pharmaceutical Co., Ltd.	Stabilisierte interleukin-1-beta enthaltende zusammensetzung
US4939176A (en) *	1988-12-20	1990-07-03	Miles Inc.	Viral inactivation process
JPH0327320A (ja) *	1989-06-26	1991-02-05	Ajinomoto Co Inc	ヒトｂ細胞分化因子医薬組成物
JPH0671434B2 (ja) *	1989-09-18	1994-09-14	株式会社ミドリ十字	ヒト血清アルブミンの製造方法
JP2949846B2 (ja) *	1990-11-30	1999-09-20	吉富製薬株式会社	アルブミン製剤の保存方法
JPH0672891A (ja) *	1992-08-31	1994-03-15	Green Cross Corp:The	ヒト血清アルブミン含有製剤
JPH07102148B2 (ja) *	1992-05-20	1995-11-08	株式会社ミドリ十字	遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物
US5440018A (en) *	1992-05-20	1995-08-08	The Green Cross Corporation	Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
JPH06247870A (ja) *	1993-02-23	1994-09-06	Ajinomoto Co Inc	インターロイキン−６を含有する医薬製剤
CA2138349A1 (en) *	1993-12-17	1995-06-18	Welfide Corporation	Method for decoloring human serum albumin
JP3533687B2 (ja) *	1993-12-17	2004-05-31	三菱ウェルファーマ株式会社	ヒト血清アルブミンの脱色方法
JP3702474B2 (ja) *	1994-06-01	2005-10-05	三菱ウェルファーマ株式会社	血清アルブミン製剤の製造方法
JP3840674B2 (ja) *	1994-08-31	2006-11-01	三菱ウェルファーマ株式会社	遺伝子操作に由来するヒト血清アルブミンの精製方法
DK0699687T3 (da)	1994-08-31	2004-04-26	Mitsubishi Pharma Corp	Fremgangsmåde til oprensning af rekombinant humant serumalbumin
JP2885212B2 (ja) *	1997-01-06	1999-04-19	吉富製薬株式会社	遺伝子操作由来のヒト血清アルブミンより得られる高純度ヒト血清アルブミン含有組成物
WO2000043035A1 (en) *	1999-01-19	2000-07-27	Nissho Corporation	Amino acid-containing albumin preparations
JP2000247903A (ja) *	1999-03-01	2000-09-12	Chugai Pharmaceut Co Ltd	長期安定化製剤
EP1762251A1 (de) *	2000-03-23	2007-03-14	Clearant, Inc.	Verfahren zum Sterilisieren biologischen Materials

2003
- 2003-02-28 US US10/505,783 patent/US7351800B2/en not_active Expired - Fee Related
- 2003-02-28 JP JP2003570867A patent/JP4259324B2/ja not_active Expired - Fee Related
- 2003-02-28 CN CNB038047799A patent/CN1330370C/zh not_active Expired - Fee Related
- 2003-02-28 AU AU2003211474A patent/AU2003211474A1/en not_active Abandoned
- 2003-02-28 WO PCT/JP2003/002320 patent/WO2003072123A1/ja not_active Ceased
- 2003-02-28 DE DE60333821T patent/DE60333821D1/de not_active Expired - Lifetime
- 2003-02-28 EP EP03743064A patent/EP1479393B1/de not_active Expired - Lifetime
- 2003-02-28 CA CA2477557A patent/CA2477557C/en not_active Expired - Fee Related
- 2003-02-28 AT AT03743064T patent/ATE477810T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP1479393B1 (de)	2010-08-18
US7351800B2 (en)	2008-04-01
EP1479393A4 (de)	2009-07-01
US20050222024A1 (en)	2005-10-06
CA2477557C (en)	2011-01-25
EP1479393A1 (de)	2004-11-24
JP4259324B2 (ja)	2009-04-30
AU2003211474A1 (en)	2003-09-09
JPWO2003072123A1 (ja)	2005-06-16
CN1330370C (zh)	2007-08-08
DE60333821D1 (de)	2010-09-30
WO2003072123A1 (fr)	2003-09-04
CA2477557A1 (en)	2003-09-04
CN1638788A (zh)	2005-07-13

Legal Events

Date	Code	Title	Description
2011-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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