ATE478061T1 - Kristalline polymorphe eines cxc- chemokinrezeptorliganden - Google Patents

Kristalline polymorphe eines cxc- chemokinrezeptorliganden

Info

Publication number
ATE478061T1
ATE478061T1 AT05712748T AT05712748T ATE478061T1 AT E478061 T1 ATE478061 T1 AT E478061T1 AT 05712748 T AT05712748 T AT 05712748T AT 05712748 T AT05712748 T AT 05712748T AT E478061 T1 ATE478061 T1 AT E478061T1
Authority
AT
Austria
Prior art keywords
polymorphos
crystalline
chemokine receptor
receptor ligand
cxc chemokine
Prior art date
Application number
AT05712748T
Other languages
English (en)
Inventor
Mengwei Hu
Younong Yu
Michael Dwyer
Arthur Taveras
Agnes Kim-Meade
Jianguo Yin
Xiaoyong Fu
Timothy Mcallister
Shuyi Zhang
Kevin Klopfer
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34837390&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE478061(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE478061T1 publication Critical patent/ATE478061T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
AT05712748T 2004-01-30 2005-01-28 Kristalline polymorphe eines cxc- chemokinrezeptorliganden ATE478061T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54048704P 2004-01-30 2004-01-30
PCT/US2005/003414 WO2005075447A1 (en) 2004-01-30 2005-01-28 Crystalline polymorphs of a cxc-chemokine receptor ligand

Publications (1)

Publication Number Publication Date
ATE478061T1 true ATE478061T1 (de) 2010-09-15

Family

ID=34837390

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05712748T ATE478061T1 (de) 2004-01-30 2005-01-28 Kristalline polymorphe eines cxc- chemokinrezeptorliganden

Country Status (25)

Country Link
US (2) US20050192345A1 (de)
EP (1) EP1723131B1 (de)
JP (2) JP2007519751A (de)
KR (1) KR100883476B1 (de)
CN (1) CN1914187B (de)
AR (1) AR047739A1 (de)
AT (1) ATE478061T1 (de)
AU (1) AU2005210504B2 (de)
BR (1) BRPI0507329A (de)
CA (1) CA2554709C (de)
CO (1) CO5700731A2 (de)
DE (1) DE602005022986D1 (de)
EC (1) ECSP066733A (de)
ES (1) ES2349788T3 (de)
IL (1) IL177033A0 (de)
MX (1) MXPA06008599A (de)
MY (1) MY144657A (de)
NO (1) NO20063841L (de)
NZ (1) NZ548499A (de)
PE (1) PE20051093A1 (de)
PL (1) PL380997A1 (de)
RU (1) RU2388756C2 (de)
TW (1) TW200536848A (de)
WO (1) WO2005075447A1 (de)
ZA (1) ZA200606295B (de)

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US20040106794A1 (en) 2001-04-16 2004-06-03 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
US7132445B2 (en) * 2001-04-16 2006-11-07 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
WO2006051340A1 (en) * 2004-07-22 2006-05-18 Pliva - Istrazivanje I Razvoj D.O.O. Novel form of celecoxib
GB2418427A (en) 2004-09-02 2006-03-29 Univ Cambridge Tech Ligands for G-protein coupled receptors
AU2007258325B2 (en) 2006-06-12 2013-02-21 Merck Sharp & Dohme Corp. Pharmaceutical formulations and compositions of a selective antagonist of either CXCR2 or both CXCR1 and CXCR2 and methods of using the same for treating inflammatory disorders
WO2009005801A1 (en) * 2007-07-03 2009-01-08 Schering Corporation Process and intermediates for the synthesis of 1,2-substituted 3,4-dioxo-1-cyclobutene compounds
CN101778836A (zh) * 2007-07-05 2010-07-14 先灵公司 在1,2-取代的3,4-二氧-1-环丁烯化合物中控制的晶体大小的方法
CA2706883A1 (en) * 2007-12-04 2009-06-11 Schering Corporation Methods of treating copd
GB2455539B (en) * 2007-12-12 2012-01-18 Cambridge Entpr Ltd Anti-inflammatory compositions and combinations
UA103198C2 (en) 2008-08-04 2013-09-25 Новартис Аг Squaramide derivatives as cxcr2 antagonists
WO2010063802A1 (en) * 2008-12-05 2010-06-10 Novartis Ag 3, 4-di-substituted cyclobutene- 1, 2 -diones as cxcr2 receptor antagonists
EP2509596B1 (de) 2009-12-08 2019-08-28 Case Western Reserve University Gamma aminosäure zur behandlung von augenerkrankungen
SI2760821T1 (en) 2011-09-02 2018-02-28 Novartis Ag A salt salt of an anti-inflammatory substituted cyclobutenedione compound
US8865723B2 (en) 2012-10-25 2014-10-21 Tetra Discovery Partners Llc Selective PDE4 B inhibition and improvement in cognition in subjects with brain injury
US9763992B2 (en) 2014-02-13 2017-09-19 Father Flanagan's Boys' Home Treatment of noise induced hearing loss
TWI724056B (zh) 2015-11-19 2021-04-11 美商卡默森屈有限公司 Ｃｘｃｒ２抑制劑
TWI734715B (zh) 2015-11-19 2021-08-01 美商卡默森屈有限公司 趨化因子受體調節劑
EP3426253A4 (de) 2016-03-11 2019-11-06 Ardea Biosciences, Inc. Cxcr-2-inhibitoren zur behandlung von kristallarthropathien
WO2019055509A1 (en) * 2017-09-12 2019-03-21 Ardea Biosciences, Inc. INHIBITORS OF CXCR-2 FOR THE TREATMENT OF DISORDERS
MA50424A (fr) 2018-01-08 2020-08-26 Chemocentryx Inc Méthodes de traitement du psoriasis pustuleux généralisé avec un antagoniste de ccr6 ou cxcr2
EP4686469A1 (de) * 2024-07-31 2026-02-04 Dompé farmaceutici SpA Cxcl8-inhibitoren zur verwendung bei der behandlung von diabetes-assoziierten erkrankungen

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US5125894A (en) * 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
EE9600184A (et) * 1994-06-27 1997-06-16 Cytomed, Inc. Kardiovaskulaar-, inflammatoor- ja immuunhaiguste raviühendid ja -meetodid
US7027859B1 (en) * 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
RU2220721C2 (ru) * 1997-12-24 2004-01-10 Санкио Компани, Лимитед Активный агент для ингибирования роста опухолей у млекопитающих, лечения и/или профилактики связанных с опухолями нарушений и метастаз опухолей у млекопитающих
ES2287284T3 (es) * 2001-04-16 2007-12-16 Schering Corporation Ciclobuteno-1,2-dionas disustituidas en las posiciones 3,4 como ligandos de receptores de quimiocinas cxc.
US7132445B2 (en) * 2001-04-16 2006-11-07 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
US20040053953A1 (en) * 2002-03-18 2004-03-18 Schering Corporation Treatment of chemokine mediated diseases
ATE457307T1 (de) * 2003-04-18 2010-02-15 Schering Corp Synthese von 2-hydroxy-n,n-dimethyl-3-[[2-[1(r)- (5-methyl-2-furanyl)propyl amino -3,4-dioxo-1- cyclobuten-1-yl amino benzamid

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AU2005210504B2 (en) 2009-01-08
RU2006131050A (ru) 2008-03-10
TW200536848A (en) 2005-11-16
NZ548499A (en) 2010-06-25
MXPA06008599A (es) 2006-08-28
AU2005210504A1 (en) 2005-08-18
US20080279822A1 (en) 2008-11-13
RU2388756C2 (ru) 2010-05-10
AR047739A1 (es) 2006-02-15
JP2011042692A (ja) 2011-03-03
KR100883476B1 (ko) 2009-02-16
ZA200606295B (en) 2008-02-27
PE20051093A1 (es) 2006-01-16
WO2005075447A1 (en) 2005-08-18
IL177033A0 (en) 2006-12-10
CO5700731A2 (es) 2006-11-30
DE602005022986D1 (de) 2010-09-30
US8207221B2 (en) 2012-06-26
KR20060128981A (ko) 2006-12-14
ECSP066733A (es) 2006-11-24
CA2554709C (en) 2011-11-15
HK1091496A1 (en) 2007-01-19
CN1914187B (zh) 2012-01-25
EP1723131A1 (de) 2006-11-22
BRPI0507329A (pt) 2007-07-03
CN1914187A (zh) 2007-02-14
CA2554709A1 (en) 2005-08-18
US20050192345A1 (en) 2005-09-01
MY144657A (en) 2011-10-31
JP2007519751A (ja) 2007-07-19
NO20063841L (no) 2006-10-27
PL380997A1 (pl) 2007-04-16
EP1723131B1 (de) 2010-08-18
ES2349788T3 (es) 2011-01-11

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