ATE478960T1 - Verfahren zur herstellung eines vitamin e - zwischenproduktes - Google Patents

Verfahren zur herstellung eines vitamin e - zwischenproduktes

Info

Publication number: ATE478960T1
Authority: AT; Austria
Prior art keywords: trimethylhydroquinone; vitamin; producing; monoacetate; intermediate product
Prior art date: 2001-02-21

Application number

AT02003627T

Other languages

English (en)

Inventor

Werner Bonrath

Detlef Eisenkraetzer

Valerie Enjolras

Reinhard Karge

Thomas Netscher

Michael Schneider

Original Assignee

Dsm Ip Assets Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-21

Filing date

2002-02-16

Publication date

2010-09-15

2002-02-16 Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv

2010-09-15 Application granted granted Critical

2010-09-15 Publication of ATE478960T1 publication Critical patent/ATE478960T1/de

Links

239000013067 intermediate product Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
229940088594 vitamin Drugs 0.000 title 1
229930003231 vitamin Natural products 0.000 title 1
235000013343 vitamin Nutrition 0.000 title 1
239000011782 vitamin Substances 0.000 title 1
150000003722 vitamin derivatives Chemical class 0.000 title 1
JFNARRJEBQBMJF-UHFFFAOYSA-N (4-hydroxy-2,3,6-trimethylphenyl) acetate Chemical compound CC(=O)OC1=C(C)C=C(O)C(C)=C1C JFNARRJEBQBMJF-UHFFFAOYSA-N 0.000 abstract 2
102000004190 Enzymes Human genes 0.000 abstract 2
108090000790 Enzymes Proteins 0.000 abstract 2
JXLWCZWBHZGUEE-UHFFFAOYSA-N (4-acetyloxy-2,3,5-trimethylphenyl) acetate Chemical compound CC(=O)OC1=CC(C)=C(OC(C)=O)C(C)=C1C JXLWCZWBHZGUEE-UHFFFAOYSA-N 0.000 abstract 1
QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
KEVYVLWNCKMXJX-ZCNNSNEGSA-N Isophytol Natural products CC(C)CCC[C@H](C)CCC[C@@H](C)CCC[C@@](C)(O)C=C KEVYVLWNCKMXJX-ZCNNSNEGSA-N 0.000 abstract 1
102000004882 Lipase Human genes 0.000 abstract 1
108090001060 Lipase Proteins 0.000 abstract 1
239000004367 Lipase Substances 0.000 abstract 1
230000021736 acetylation Effects 0.000 abstract 1
238000006640 acetylation reaction Methods 0.000 abstract 1
239000012876 carrier material Substances 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000002255 enzymatic effect Effects 0.000 abstract 1
235000019421 lipase Nutrition 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Steroid Compounds (AREA)
Pyrane Compounds (AREA)

AT02003627T 2001-02-21 2002-02-16 Verfahren zur herstellung eines vitamin e - zwischenproduktes ATE478960T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01104141		2001-02-21

Publications (1)

Publication Number	Publication Date
ATE478960T1 true ATE478960T1 (de)	2010-09-15

Family

ID=8176554

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02003627T ATE478960T1 (de)	2001-02-21	2002-02-16	Verfahren zur herstellung eines vitamin e - zwischenproduktes

Country Status (8)

Country	Link
US (1)	US6743615B2 (de)
EP (1)	EP1239045B1 (de)
JP (1)	JP2002291495A (de)
KR (1)	KR100831541B1 (de)
CN (1)	CN1242067C (de)
AT (1)	ATE478960T1 (de)
DE (1)	DE60237411D1 (de)
ES (1)	ES2350741T3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1562929B1 (de) *	2002-11-21	2007-11-14	DSM IP Assets B.V.	Herstellung von tocoferylazetaten
KR101154117B1 (ko)	2003-01-13	2012-06-11	디에스엠 아이피 어셋츠 비.브이.	α-토코페릴 아세테이트의 제조방법
CN103627741B (zh) *	2013-11-28	2016-03-09	浙江工业大学	一种三甲基氢醌-1-乙酸酯的制备方法
CN115927288A (zh) *	2022-07-28	2023-04-07	南京林业大学	一种固定化脂肪tll酶及固体结合肽在其固定化中的应用
CN115745938B (zh) *	2022-11-15	2024-05-03	万华化学集团股份有限公司	一种连续制备维生素e乙酸酯的方法
WO2025242782A1 (en) *	2024-05-23	2025-11-27	Dsm Ip Assets B.V.	Mono-saponifaction of diesters of trimethylhydroquinone and its use in the process of manufacturing esterified alpha-tocopherol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5445951A (en) *	1993-02-02	1995-08-29	Mcneil-Ppc, Inc.	Regioselective enzymatic deacylation of sucrose esters in anhydrous organic media
JP3638644B2 (ja) *	1994-10-18	2005-04-13	株式会社クラレ	光学活性クロマン化合物の製造方法

2002
- 2002-02-16 ES ES02003627T patent/ES2350741T3/es not_active Expired - Lifetime
- 2002-02-16 DE DE60237411T patent/DE60237411D1/de not_active Expired - Lifetime
- 2002-02-16 AT AT02003627T patent/ATE478960T1/de not_active IP Right Cessation
- 2002-02-16 EP EP02003627A patent/EP1239045B1/de not_active Expired - Lifetime
- 2002-02-18 JP JP2002039852A patent/JP2002291495A/ja active Pending
- 2002-02-19 US US10/078,789 patent/US6743615B2/en not_active Expired - Lifetime
- 2002-02-20 KR KR1020020008903A patent/KR100831541B1/ko not_active Expired - Fee Related
- 2002-02-20 CN CNB021050872A patent/CN1242067C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CN1242067C (zh)	2006-02-15
EP1239045A1 (de)	2002-09-11
US20020161246A1 (en)	2002-10-31
US6743615B2 (en)	2004-06-01
CN1373225A (zh)	2002-10-09
KR100831541B1 (ko)	2008-05-21
ES2350741T3 (es)	2011-01-26
JP2002291495A (ja)	2002-10-08
EP1239045B1 (de)	2010-08-25
DE60237411D1 (de)	2010-10-07
KR20020068461A (ko)	2002-08-27

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Legal Events

Date	Code	Title	Description
2011-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties