ATE479758T1 - (r)-2-octanol dehydrogenasen, verfahren zur herstellung dieser enzyme, dna, welche für dieser enzyme kodiert, und verfahren zur herstellung von alkoholen durch anwendung der enzyme - Google Patents
(r)-2-octanol dehydrogenasen, verfahren zur herstellung dieser enzyme, dna, welche für dieser enzyme kodiert, und verfahren zur herstellung von alkoholen durch anwendung der enzymeInfo
- Publication number
- ATE479758T1 ATE479758T1 AT01904474T AT01904474T ATE479758T1 AT E479758 T1 ATE479758 T1 AT E479758T1 AT 01904474 T AT01904474 T AT 01904474T AT 01904474 T AT01904474 T AT 01904474T AT E479758 T1 ATE479758 T1 AT E479758T1
- Authority
- AT
- Austria
- Prior art keywords
- enzymes
- producing
- octanol
- alcohols
- dehydrogenases
- Prior art date
Links
- 108090000790 Enzymes Proteins 0.000 title abstract 4
- 102000004190 Enzymes Human genes 0.000 title abstract 4
- 150000001298 alcohols Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 2
- 108020005199 Dehydrogenases Proteins 0.000 title 1
- SJWFXCIHNDVPSH-MRVPVSSYSA-N (2R)-octan-2-ol Chemical compound CCCCCC[C@@H](C)O SJWFXCIHNDVPSH-MRVPVSSYSA-N 0.000 abstract 3
- 101710088194 Dehydrogenase Proteins 0.000 abstract 3
- 241000222120 Candida <Saccharomycetales> Species 0.000 abstract 1
- 241001112159 Ogataea Species 0.000 abstract 1
- 241000235648 Pichia Species 0.000 abstract 1
- 239000005515 coenzyme Substances 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 abstract 1
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000006479 redox reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000043506 | 2000-02-16 | ||
| JP2000374593 | 2000-12-08 | ||
| PCT/JP2001/001082 WO2001061014A1 (en) | 2000-02-16 | 2001-02-15 | (r)-2-octanol dehydrogenase, process for producing the enzyme, dna encoding the enzyme and process for producing alcohol by using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE479758T1 true ATE479758T1 (de) | 2010-09-15 |
Family
ID=26585778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01904474T ATE479758T1 (de) | 2000-02-16 | 2001-02-15 | (r)-2-octanol dehydrogenasen, verfahren zur herstellung dieser enzyme, dna, welche für dieser enzyme kodiert, und verfahren zur herstellung von alkoholen durch anwendung der enzyme |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6706507B2 (de) |
| EP (1) | EP1179595B1 (de) |
| JP (1) | JP4651896B2 (de) |
| KR (1) | KR100760106B1 (de) |
| CN (1) | CN100413967C (de) |
| AT (1) | ATE479758T1 (de) |
| CZ (1) | CZ300833B6 (de) |
| DE (1) | DE60142949D1 (de) |
| TW (1) | TWI275645B (de) |
| WO (1) | WO2001061014A1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003230398A (ja) | 2001-12-07 | 2003-08-19 | Daicel Chem Ind Ltd | 光学活性アルコールの製造方法 |
| EP1318200A3 (de) * | 2001-12-07 | 2004-04-07 | Daicel Chemical Industries, Ltd. | Verfahren zur Herstellung von optisch aktiven Alkoholen |
| JP2007274901A (ja) * | 2004-05-12 | 2007-10-25 | Taisho Pharmaceut Co Ltd | 光学活性プロパルギルアルコールの製造方法 |
| US20060177913A1 (en) * | 2005-02-08 | 2006-08-10 | Consortium Fur Elektrochemische Industrie Gmbh | Process for enantioselective enzymatic reduction of keto compounds |
| AT501496B1 (de) * | 2005-02-21 | 2007-03-15 | Iep Gmbh | Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen |
| JP4796787B2 (ja) * | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類への遺伝子導入法 |
| JP4796786B2 (ja) * | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類を形質転換可能なベクター |
| AT502395B1 (de) * | 2005-07-27 | 2007-03-15 | Iep Gmbh | Oxidoreduktasen zur stereoselektiven reduktion von ketoverbindungen |
| DE102006009744A1 (de) * | 2006-03-02 | 2007-09-06 | Wacker Chemie Ag | Herstellung von (S)-2-Butanol durch oxidative Racematspaltung |
| JP5261172B2 (ja) | 2006-03-31 | 2013-08-14 | 株式会社カネカ | エリスロ又はスレオ−２−アミノ−３−ヒドロキシプロピオン酸エステルの製造方法、新規カルボニル還元酵素、その遺伝子、ベクター、形質転換体、およびそれらを利用した光学活性アルコールの製造方法 |
| AT503486B1 (de) | 2006-04-11 | 2008-05-15 | Iep Gmbh | Verfahren zur enantioselektiven reduktion von steroiden |
| EP2034026A4 (de) | 2006-06-05 | 2012-01-04 | Daicel Chem | Verfahren zur herstellung von optisch aktivem alkohol |
| CN101381735A (zh) * | 2007-09-06 | 2009-03-11 | 南开大学 | 嗜热长链烷醇醇脱氢酶及其编码基因与应用 |
| AT506639A1 (de) * | 2008-04-01 | 2009-10-15 | Kroutil Wolfgang Dipl Ing Dr T | Verfahren zur deracemisierung von enantiomerengemischen unter verwendung von enzymsystemen |
| EP2329013B1 (de) | 2008-08-27 | 2015-10-28 | Codexis, Inc. | Ketoreduktasepolypeptide zur herstellung von einem 3-aryl-3-hydroxypropanamin aus einem 3-aryl-3-ketopropanamin |
| WO2010025287A2 (en) | 2008-08-27 | 2010-03-04 | Codexis, Inc. | Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine |
| US8273554B2 (en) | 2008-08-29 | 2012-09-25 | Codexis, Inc. | Ketoreductase polypeptides for the stereoselective production of (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one |
| EP2226386A1 (de) | 2009-03-05 | 2010-09-08 | IEP GmbH | Verfahren zur stereoselektiven enzymatischen Reduktion von Ketoverbindungen |
| CN101899495B (zh) * | 2009-06-04 | 2013-08-28 | 江南大学 | 一株不对称性还原4-羟基-2-丁酮为光学纯(r)-1,3-丁二醇酵母菌株的选育 |
| ES2575560T3 (es) | 2009-08-19 | 2016-06-29 | Codexis, Inc. | Polipéptidos cetorreductasa para preparar fenilefrina |
| NZ600509A (en) | 2009-12-29 | 2014-08-29 | Butamax Tm Advanced Biofuels | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
| HUE026367T2 (en) | 2010-05-04 | 2016-06-28 | Codexis Inc | Biocatalysts for ezetimibe synthesis |
| US9096825B2 (en) | 2010-05-27 | 2015-08-04 | Pharmazell Gmbh | 7 α-hydroxysteroid dehydrogenase knockout mutants and use therefor |
| CN102925501A (zh) * | 2012-11-19 | 2013-02-13 | 苏州汉酶生物技术有限公司 | 一种(s)-4-氯-3-羟基丁酸乙酯的生物制备方法 |
| CN107782684A (zh) * | 2017-10-09 | 2018-03-09 | 苏州科铭生物技术有限公司 | 辅酶ⅱnadp+或nadph含量测定试剂盒及其方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3711881A1 (de) * | 1987-04-08 | 1988-10-27 | Merck Patent Gmbh | Verfahren zur herstellung von glucosedehydrogenase aus bacillus megaterium |
| JPH01277494A (ja) * | 1988-04-28 | 1989-11-07 | Agency Of Ind Science & Technol | 光学活性アルコールの製造方法 |
| JPH01281092A (ja) * | 1988-05-09 | 1989-11-13 | Agency Of Ind Science & Technol | 光学活性な左旋性の（−）―（□ｄｒ）―１―ヒドロキシエチルフェロセンの製造方法 |
| JPH04360697A (ja) * | 1991-06-04 | 1992-12-14 | Showa Sangyo Co Ltd | Ｒ体第２級アルコールの製造方法 |
| DE4205391A1 (de) * | 1992-02-21 | 1993-08-26 | Basf Ag | Verfahren zur enzymatischen oxidation von (d)-2-hydroxycarbonsaeuren zu 2-ketocarbonsaeuren |
| US5385833A (en) | 1992-02-26 | 1995-01-31 | The Scripps Research Institute | Pseudomonas sp. ATCC No. 49794 alcohol dehydrogenase |
| JP4012257B2 (ja) | 1997-02-07 | 2007-11-21 | 株式会社カネカ | 新規カルボニル還元酵素、およびこれをコードする遺伝子、ならびにこれらの利用方法 |
| JP2000236883A (ja) | 1998-12-21 | 2000-09-05 | Daicel Chem Ind Ltd | 新規なカルボニル還元酵素、該酵素の製造方法、該酵素をコードするｄｎａおよびこれを利用したアルコールの製造方法 |
| HUP0105169A3 (en) * | 1999-07-21 | 2004-03-01 | Kaneka Corp | Process for producing optically active pyridineethanol derivatives |
| DE10037101A1 (de) * | 2000-07-27 | 2002-02-07 | Degussa | Rekombinant hergestellte Enzyme mit verbesserter NAD(H)-Akzeptanz |
-
2001
- 2001-02-07 TW TW(R)-2-OCTA patent/TWI275645B/zh not_active IP Right Cessation
- 2001-02-15 EP EP01904474A patent/EP1179595B1/de not_active Expired - Lifetime
- 2001-02-15 JP JP2001559851A patent/JP4651896B2/ja not_active Expired - Lifetime
- 2001-02-15 WO PCT/JP2001/001082 patent/WO2001061014A1/ja not_active Ceased
- 2001-02-15 CN CNB018007589A patent/CN100413967C/zh not_active Expired - Fee Related
- 2001-02-15 KR KR1020017012994A patent/KR100760106B1/ko not_active Expired - Fee Related
- 2001-02-15 CZ CZ20013768A patent/CZ300833B6/cs not_active IP Right Cessation
- 2001-02-15 AT AT01904474T patent/ATE479758T1/de active
- 2001-02-15 DE DE60142949T patent/DE60142949D1/de not_active Expired - Lifetime
- 2001-10-16 US US09/978,758 patent/US6706507B2/en not_active Expired - Fee Related
-
2004
- 2004-01-27 US US10/766,421 patent/US7202069B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN100413967C (zh) | 2008-08-27 |
| EP1179595A4 (de) | 2004-12-08 |
| CZ20013768A3 (cs) | 2002-04-17 |
| KR20010113790A (ko) | 2001-12-28 |
| CZ300833B6 (cs) | 2009-08-19 |
| WO2001061014A1 (en) | 2001-08-23 |
| KR100760106B1 (ko) | 2007-09-18 |
| US20020192783A1 (en) | 2002-12-19 |
| EP1179595B1 (de) | 2010-09-01 |
| TWI275645B (en) | 2007-03-11 |
| DE60142949D1 (de) | 2010-10-14 |
| JP4651896B2 (ja) | 2011-03-16 |
| EP1179595A1 (de) | 2002-02-13 |
| US20040126857A1 (en) | 2004-07-01 |
| US6706507B2 (en) | 2004-03-16 |
| US7202069B2 (en) | 2007-04-10 |
| CN1366550A (zh) | 2002-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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