ATE480512T1 - Verfahren zur herstellung einer epoxytriazolverbindung und zwischenprodukt dafür - Google Patents
Verfahren zur herstellung einer epoxytriazolverbindung und zwischenprodukt dafürInfo
- Publication number
- ATE480512T1 ATE480512T1 AT04819487T AT04819487T ATE480512T1 AT E480512 T1 ATE480512 T1 AT E480512T1 AT 04819487 T AT04819487 T AT 04819487T AT 04819487 T AT04819487 T AT 04819487T AT E480512 T1 ATE480512 T1 AT E480512T1
- Authority
- AT
- Austria
- Prior art keywords
- compound
- producing
- formula
- reaction step
- epoxytriazole
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 abstract 4
- NSPMIYGKQJPBQR-UHFFFAOYSA-N 4H-1,2,4-triazole Chemical compound C=1N=CNN=1 NSPMIYGKQJPBQR-UHFFFAOYSA-N 0.000 abstract 2
- 238000010511 deprotection reaction Methods 0.000 abstract 2
- 125000004212 difluorophenyl group Chemical group 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003398252A JP4404611B2 (ja) | 2003-11-27 | 2003-11-27 | エポキシトリアゾール化合物の製造方法及びその中間体 |
| PCT/JP2004/017992 WO2005051879A1 (ja) | 2003-11-27 | 2004-11-26 | エポキシトリアゾール化合物の製造方法及びその中間体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE480512T1 true ATE480512T1 (de) | 2010-09-15 |
Family
ID=34631561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04819487T ATE480512T1 (de) | 2003-11-27 | 2004-11-26 | Verfahren zur herstellung einer epoxytriazolverbindung und zwischenprodukt dafür |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1693358B1 (de) |
| JP (1) | JP4404611B2 (de) |
| CN (2) | CN101250163B (de) |
| AT (1) | ATE480512T1 (de) |
| DE (1) | DE602004029079D1 (de) |
| ES (1) | ES2349931T3 (de) |
| WO (1) | WO2005051879A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5654738B2 (ja) * | 2008-08-08 | 2015-01-14 | 株式会社カネカ | エポキシトリアゾール誘導体の製造法 |
| WO2016079728A1 (en) | 2014-11-23 | 2016-05-26 | Mapi Pharma Ltd. | Intermediate compounds and process for the preparation of efinaconazole |
| CN106608867B (zh) * | 2015-10-23 | 2019-09-13 | 山东威智医药工业有限公司 | 艾氟康唑及其中间体的制备方法、其中间体 |
| CN106957306A (zh) * | 2016-01-11 | 2017-07-18 | 武汉诺安药业有限公司 | 一种艾氟康唑中间体的合成方法 |
| CN110997646B (zh) * | 2017-08-10 | 2023-06-20 | 住友化学株式会社 | 环氧醇化合物的制造方法 |
| CN110862355A (zh) * | 2019-12-03 | 2020-03-06 | 济南大学 | 一种艾氟康唑中间体的合成方法 |
| CN119823049B (zh) * | 2023-10-12 | 2025-10-10 | 中国石油化工股份有限公司 | 一种改性咪唑啉型季铵盐的制备方法与改性咪唑啉缓蚀剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE903395A1 (en) * | 1989-09-26 | 1991-04-10 | Takeda Chemical Industries Ltd | Triazole compounds, their production and use |
| JP3008029B2 (ja) * | 1989-09-26 | 2000-02-14 | 武田薬品工業株式会社 | メルカプト化合物の製造法 |
| JPH04356471A (ja) | 1991-03-25 | 1992-12-10 | Takeda Chem Ind Ltd | トリアゾール化合物およびその用途 |
| WO1999045008A1 (en) * | 1998-03-06 | 1999-09-10 | F. Hoffmann-La Roche Ag | 3-[4-(4-cyanophenyl)thiazol-2-y)]-1-(1h-1,2,4-triazol-1-yl)-butan-2-ol derivatives having antifungal activity |
| AU2003211498A1 (en) * | 2002-02-15 | 2003-09-04 | Mitsui Chemicals, Inc. | Optically active azole derivative and process for producing the same |
-
2003
- 2003-11-27 JP JP2003398252A patent/JP4404611B2/ja not_active Expired - Fee Related
-
2004
- 2004-11-26 DE DE602004029079T patent/DE602004029079D1/de not_active Expired - Lifetime
- 2004-11-26 CN CN2008100817727A patent/CN101250163B/zh not_active Expired - Fee Related
- 2004-11-26 ES ES04819487T patent/ES2349931T3/es not_active Expired - Lifetime
- 2004-11-26 EP EP04819487A patent/EP1693358B1/de not_active Expired - Lifetime
- 2004-11-26 CN CNB2004800408532A patent/CN100491319C/zh not_active Expired - Fee Related
- 2004-11-26 WO PCT/JP2004/017992 patent/WO2005051879A1/ja not_active Ceased
- 2004-11-26 AT AT04819487T patent/ATE480512T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN100491319C (zh) | 2009-05-27 |
| EP1693358A1 (de) | 2006-08-23 |
| CN101250163B (zh) | 2011-02-23 |
| CN1906146A (zh) | 2007-01-31 |
| DE602004029079D1 (de) | 2010-10-21 |
| ES2349931T3 (es) | 2011-01-13 |
| JP4404611B2 (ja) | 2010-01-27 |
| EP1693358A4 (de) | 2007-10-17 |
| JP2005154377A (ja) | 2005-06-16 |
| CN101250163A (zh) | 2008-08-27 |
| WO2005051879A1 (ja) | 2005-06-09 |
| EP1693358B1 (de) | 2010-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |