ATE482182T1 - Asymmetrische hydrierung zur herstellung von diphenylalaninderivaten - Google Patents
Asymmetrische hydrierung zur herstellung von diphenylalaninderivatenInfo
- Publication number
- ATE482182T1 ATE482182T1 AT06770147T AT06770147T ATE482182T1 AT E482182 T1 ATE482182 T1 AT E482182T1 AT 06770147 T AT06770147 T AT 06770147T AT 06770147 T AT06770147 T AT 06770147T AT E482182 T1 ATE482182 T1 AT E482182T1
- Authority
- AT
- Austria
- Prior art keywords
- diphenylalanine
- derivatives
- production
- asymmetric hydrogenation
- hydrogenation
- Prior art date
Links
- PECGVEGMRUZOML-AWEZNQCLSA-N (2s)-2-amino-3,3-diphenylpropanoic acid Chemical class C=1C=CC=CC=1C([C@H](N)C(O)=O)C1=CC=CC=C1 PECGVEGMRUZOML-AWEZNQCLSA-N 0.000 title abstract 2
- 238000009876 asymmetric hydrogenation reaction Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 229910052703 rhodium Inorganic materials 0.000 abstract 1
- 239000010948 rhodium Substances 0.000 abstract 1
- MHOVAHRLVXNVSD-UHFFFAOYSA-N rhodium atom Chemical compound [Rh] MHOVAHRLVXNVSD-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68315005P | 2005-05-20 | 2005-05-20 | |
| PCT/US2006/017978 WO2006127273A2 (en) | 2005-05-20 | 2006-05-09 | Asymmetric hydrogenation for the preparation of diphenylalanine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE482182T1 true ATE482182T1 (de) | 2010-10-15 |
Family
ID=37027602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06770147T ATE482182T1 (de) | 2005-05-20 | 2006-05-09 | Asymmetrische hydrierung zur herstellung von diphenylalaninderivaten |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1885688B1 (de) |
| JP (1) | JP5001263B2 (de) |
| CN (1) | CN101175715B (de) |
| AT (1) | ATE482182T1 (de) |
| DE (1) | DE602006017064D1 (de) |
| WO (1) | WO2006127273A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011519340A (ja) * | 2007-10-30 | 2011-07-07 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 置換アルカン酸調製のためのエナンチオ選択的プロセスこの米国特許正規出願は、２００７年１０月３０日に提出された米国特許仮出願第６１／００１，００４号、及び２００８年２月２９日に提出された米国特許仮出願第６１／０６７，８４２号の権利を主張する。 |
| AU2021318923A1 (en) * | 2020-07-28 | 2023-03-09 | Jazz Pharmaceuticals Ireland Limited | Chiral synthesis of fused bicyclic Raf inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198548A (en) * | 1992-01-30 | 1993-03-30 | Warner-Lambert Company | Process for the preparation of D(-) and L(+)-3,3-diphenylalanine and D(-) and L(+)-substituted 3,3-diphenylalanines and derivatives thereof |
| US5874629A (en) * | 1996-06-12 | 1999-02-23 | Merck & Co., Inc. | Chiral bisphosphines |
| ATE318271T1 (de) * | 2001-01-19 | 2006-03-15 | Chirotech Technology Ltd | Liganden und deren verwendung |
| WO2005118529A2 (en) * | 2004-05-11 | 2005-12-15 | Merck & Co., Inc. | Process for making n-sulfonated-amino acid derivatives |
-
2006
- 2006-05-09 AT AT06770147T patent/ATE482182T1/de not_active IP Right Cessation
- 2006-05-09 DE DE602006017064T patent/DE602006017064D1/de active Active
- 2006-05-09 JP JP2008512351A patent/JP5001263B2/ja not_active Expired - Fee Related
- 2006-05-09 EP EP06770147A patent/EP1885688B1/de not_active Not-in-force
- 2006-05-09 WO PCT/US2006/017978 patent/WO2006127273A2/en not_active Ceased
- 2006-05-09 CN CN2006800170720A patent/CN101175715B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101175715A (zh) | 2008-05-07 |
| DE602006017064D1 (de) | 2010-11-04 |
| WO2006127273A3 (en) | 2007-03-22 |
| EP1885688B1 (de) | 2010-09-22 |
| WO2006127273A2 (en) | 2006-11-30 |
| JP2008540650A (ja) | 2008-11-20 |
| EP1885688A2 (de) | 2008-02-13 |
| JP5001263B2 (ja) | 2012-08-15 |
| CN101175715B (zh) | 2011-04-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |