ATE482689T1 - Blockcopolymer-mizellenzusammensetzung mit verbesserter arzneimittelbeladungskapazität und verzögerter freisetzung - Google Patents

Blockcopolymer-mizellenzusammensetzung mit verbesserter arzneimittelbeladungskapazität und verzögerter freisetzung

Info

Publication number
ATE482689T1
ATE482689T1 AT03794297T AT03794297T ATE482689T1 AT E482689 T1 ATE482689 T1 AT E482689T1 AT 03794297 T AT03794297 T AT 03794297T AT 03794297 T AT03794297 T AT 03794297T AT E482689 T1 ATE482689 T1 AT E482689T1
Authority
AT
Austria
Prior art keywords
block copolymer
loading capacity
sustained release
drug loading
improved drug
Prior art date
Application number
AT03794297T
Other languages
English (en)
Inventor
Kilwon Cho
Jae Young Lee
Original Assignee
Postech Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Postech Foundation filed Critical Postech Foundation
Application granted granted Critical
Publication of ATE482689T1 publication Critical patent/ATE482689T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Graft Or Block Polymers (AREA)
AT03794297T 2002-09-04 2003-05-30 Blockcopolymer-mizellenzusammensetzung mit verbesserter arzneimittelbeladungskapazität und verzögerter freisetzung ATE482689T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2002-0053090A KR100502840B1 (ko) 2002-09-04 2002-09-04 약물 담지능력이 우수한 블록 공중합체 미셀 조성물
PCT/KR2003/001065 WO2004022036A1 (en) 2002-09-04 2003-05-30 Block copolymer micelle composition having an enhanced drug-loading capacity and sustained release

Publications (1)

Publication Number Publication Date
ATE482689T1 true ATE482689T1 (de) 2010-10-15

Family

ID=31973649

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03794297T ATE482689T1 (de) 2002-09-04 2003-05-30 Blockcopolymer-mizellenzusammensetzung mit verbesserter arzneimittelbeladungskapazität und verzögerter freisetzung

Country Status (6)

Country Link
US (1) US7744919B2 (de)
EP (1) EP1539109B1 (de)
KR (1) KR100502840B1 (de)
AT (1) ATE482689T1 (de)
DE (1) DE60334388D1 (de)
WO (1) WO2004022036A1 (de)

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US7649023B2 (en) 2002-06-11 2010-01-19 Novartis Ag Biodegradable block copolymeric compositions for drug delivery
US20070086975A1 (en) * 2003-12-17 2007-04-19 Francis Ignatious Polymeric micellar complexes and drug delivery vehicles thereof
EP1732485A2 (de) * 2004-01-02 2006-12-20 Wisconsin Alumni Research Foundation Verkapselung von chemischen verbindungen in mizellen mit fluorhaltigem kern und fluorhaltiger innerer schale aus blockcopolymeren mit teilfluorierten oder fluorierten blöcken
US20090181098A1 (en) 2006-03-07 2009-07-16 Osteoscreen Ip, Llc Hmg-Co-a Reductase Inhibitor Enhancement of Bone and Cartilage
ATE506861T1 (de) * 2006-03-27 2011-05-15 Nestec Sa Molkenproteinträger zur abgabe von aktivsubstanzen
BRPI0716890A2 (pt) * 2006-09-22 2013-10-22 Labopharm Inc Composição, e, método de produção de uma composição, de administração de um agente farmaceuticamente ativo insolúvel em água a um mamífero, e de tratamento de câncer em um mamífero
EP2099408B1 (de) * 2006-11-28 2016-10-05 Wisconsin Alumni Research Foundation Emulsionen auf fluorpolymerbasis zur intravenösen verabreichung flüchtiger fluorinierter anästhetika
US8900562B2 (en) * 2007-01-12 2014-12-02 Wisconsin Alumni Research Foundation Semi-fluorinated block copolymers for delivery of therapeutic agents
KR20080095130A (ko) * 2007-04-23 2008-10-28 한국과학기술연구원 ｐＨ 민감성 블록공중합체를 이용한 약물전달체 제조 및응용
KR101005562B1 (ko) * 2008-05-01 2011-01-05 한국생명공학연구원 난용성 약물을 함유하는 균일한 크기의 고분자 나노입자제조방법
KR20090115269A (ko) * 2008-05-01 2009-11-05 한국생명공학연구원 난용성 약물 함유 서방성 고분자 나노입자 제형
EP2201935B1 (de) * 2008-12-26 2020-07-08 Samyang Biopharmaceuticals Corporation Polymere Mizellenzusammensetzung, die ein schlecht lösliches Arzneimittel enthält, und zugehöriges Herstellungsverfahren
KR101286854B1 (ko) * 2011-09-29 2013-07-17 중앙대학교 산학협력단 폴리락트산（ａ）과 폴리에틸렌글리콜（ｂ）로 이루어진 ｂａｂ형 삼중 블록 공중합체, 이의 제조방법 및 이를 이용한 약물전달체
KR101495298B1 (ko) * 2013-02-20 2015-02-25 한국과학기술원 소간섭 리보핵산(siRNA)를 친수성 블록으로 갖는 양친매성 블록 공중합체 및 이를 포함하는 다중이온복합체
EP3164111B1 (de) 2014-07-02 2019-04-03 The Research Foundation for the State University of New York Tensidausgeblasene mizellenzusammensetzungen mit hohem belastung-zu-tensid-verhältnis
KR102009969B1 (ko) * 2015-11-25 2019-10-21 주식회사 엘지화학 양친성 고분자
KR102184768B1 (ko) 2018-12-31 2020-11-30 중앙대학교 산학협력단 혼합 고분자 미셀 조성물 및 이의 용도
CA3162374A1 (en) * 2019-12-20 2021-06-24 So Jin Lee Kit for preparing nanoparticle composition for drug delivery, comprising polylactic acid salt
AU2023338088A1 (en) * 2022-09-08 2025-03-13 Samyang Holdings Corporation Kit for manufacture of drug-containing nanoparticles and nanoparticle composition for drug delivery
CN116622038B (zh) * 2023-04-13 2026-02-10 湘潭大学 一种pH响应核-壳结构的包裹胰岛素纳米胶束及其制备方法

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US6649702B1 (en) 1999-05-19 2003-11-18 University Of Utah Research Foundation Stabilization and acoustic activation of polymeric micelles for drug delivery
CA2309375A1 (en) 1999-05-28 2000-11-28 Mcgill University Polycaprolactone-b-poly(ethylene oxide) copolymer micelles as a delivery vehicle for steroid
KR20010010393A (ko) * 1999-07-20 2001-02-05 김윤 소수성 고분자와 친수성 고분자의 생분해성 블록 공중합체 및이를 포함하는 약물 전달체 조성물
KR100360827B1 (ko) * 1999-08-14 2002-11-18 주식회사 삼양사 난용성 약물을 가용화하기 위한 고분자 조성물 및 그의 제조방법
JP3523821B2 (ja) * 2000-02-09 2004-04-26 ナノキャリア株式会社 薬物が封入されたポリマーミセルの製造方法および該ポリマーミセル組成物
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Also Published As

Publication number Publication date
DE60334388D1 (de) 2010-11-11
WO2004022036A1 (en) 2004-03-18
EP1539109A4 (de) 2007-08-08
KR100502840B1 (ko) 2005-07-21
EP1539109B1 (de) 2010-09-29
EP1539109A1 (de) 2005-06-15
KR20040021760A (ko) 2004-03-11
US20050287196A1 (en) 2005-12-29
US7744919B2 (en) 2010-06-29

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