ATE482703T1 - Gelzusammensetzung zur behandlung von mykose - Google Patents
Gelzusammensetzung zur behandlung von mykoseInfo
- Publication number
- ATE482703T1 ATE482703T1 AT07860506T AT07860506T ATE482703T1 AT E482703 T1 ATE482703 T1 AT E482703T1 AT 07860506 T AT07860506 T AT 07860506T AT 07860506 T AT07860506 T AT 07860506T AT E482703 T1 ATE482703 T1 AT E482703T1
- Authority
- AT
- Austria
- Prior art keywords
- gel composition
- present
- treatment
- mycosis
- permeation
- Prior art date
Links
- 206010017533 Fungal infection Diseases 0.000 title abstract 5
- 208000024386 fungal infectious disease Diseases 0.000 title abstract 5
- NFEZZTICAUWDHU-RDTXWAMCSA-N efinaconazole Chemical compound N1([C@H](C)[C@](O)(CN2N=CN=C2)C=2C(=CC(F)=CC=2)F)CCC(=C)CC1 NFEZZTICAUWDHU-RDTXWAMCSA-N 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 208000010195 Onychomycosis Diseases 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
- 201000005882 tinea unguium Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006354626 | 2006-12-28 | ||
| PCT/JP2007/075303 WO2008081940A1 (ja) | 2006-12-28 | 2007-12-28 | 真菌症治療用ゲル組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE482703T1 true ATE482703T1 (de) | 2010-10-15 |
Family
ID=39588620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07860506T ATE482703T1 (de) | 2006-12-28 | 2007-12-28 | Gelzusammensetzung zur behandlung von mykose |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8889155B2 (de) |
| EP (1) | EP2116243B1 (de) |
| JP (1) | JP5372523B2 (de) |
| AT (1) | ATE482703T1 (de) |
| CA (1) | CA2673976C (de) |
| DE (1) | DE602007009574D1 (de) |
| ES (1) | ES2350806T3 (de) |
| PT (1) | PT2116243E (de) |
| WO (1) | WO2008081940A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090175810A1 (en) | 2008-01-03 | 2009-07-09 | Gareth Winckle | Compositions and methods for treating diseases of the nail |
| US8039494B1 (en) | 2010-07-08 | 2011-10-18 | Dow Pharmaceutical Sciences, Inc. | Compositions and methods for treating diseases of the nail |
| PL2431030T3 (pl) * | 2010-09-17 | 2016-05-31 | Abbell Ab | Leczenie infekcji grzybiczych |
| JP5754799B2 (ja) * | 2010-12-21 | 2015-07-29 | 学校法人 聖マリアンナ医科大学 | 研磨カス飛散防止組成物 |
| AU2014329421B2 (en) * | 2013-10-03 | 2018-08-02 | Dow Pharmaceutical Sciences, Inc. | Stabilized efinaconazole compositions |
| JP6611014B2 (ja) | 2013-11-22 | 2019-11-27 | ボシュ ヘルス アイルランド リミテッド | 抗感染方法、抗感染組成物、および抗感染装置 |
| CA2974180A1 (en) * | 2015-01-20 | 2016-07-28 | Itai Adin | Crystalline forms of efinaconazole |
| KR102060546B1 (ko) * | 2019-06-07 | 2019-12-30 | 주식회사 바이오빌리프 | 에피나코나졸을 함유하는 용액 형태의 국소 투여용 약학 조성물 |
| KR20210032662A (ko) * | 2019-09-17 | 2021-03-25 | 주식회사 바이오빌리프 | 킬레이트화제를 포함하는 안정화된 에피나코나졸-함유 약학 조성물 |
| WO2021054531A2 (ko) * | 2019-09-17 | 2021-03-25 | 주식회사 바이오빌리프 | 항산화제를 포함하는 안정화된 에피나코나졸-함유 약학 조성물 |
| KR20210032665A (ko) * | 2019-09-17 | 2021-03-25 | 주식회사 바이오빌리프 | 킬레이트화제 및 항산화제의 조합을 포함하는 안정화된 에피나코나졸-함유 약학 조성물 |
| KR20210032672A (ko) * | 2019-09-17 | 2021-03-25 | 주식회사 바이오빌리프 | 에피나코나졸을 함유하는 안정화된 약학 조성물 |
| WO2021054535A2 (ko) * | 2019-09-17 | 2021-03-25 | 주식회사 바이오빌리프 | 킬레이트화제, 항산화제, 및 산의 조합을 포함하는 안정화된 에피나코나졸-함유 약학 조성물 |
| WO2021054533A2 (ko) * | 2019-09-17 | 2021-03-25 | 주식회사 바이오빌리프 | 산으로서 소르빈산을 포함하는 안정화된 에피나코나졸-함유 약학 조성물 |
| KR102266145B1 (ko) * | 2019-09-26 | 2021-06-17 | 대봉엘에스 주식회사 | 비정질 에피나코나졸 고체 분산체 |
| JP2024002166A (ja) * | 2022-06-23 | 2024-01-11 | 東和薬品株式会社 | 爪用外用剤 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6061518A (ja) * | 1983-09-14 | 1985-04-09 | Hisamitsu Pharmaceut Co Inc | ゲル状外用組成物 |
| JPH07100652B2 (ja) | 1987-05-22 | 1995-11-01 | サンスタ−株式会社 | 透明状軟膏基剤 |
| JPH02264723A (ja) * | 1989-04-06 | 1990-10-29 | Taisho Pharmaceut Co Ltd | 抗真菌剤 |
| JP3130350B2 (ja) | 1991-11-28 | 2001-01-31 | 積水化学工業株式会社 | 経皮吸収製剤 |
| UA41365C2 (uk) | 1993-05-10 | 2001-09-17 | Какєн Фармасьютікал Ко., Лтд | Похідні азоліламіну та фунгіцидний засіб на їх основі |
| JP2768830B2 (ja) | 1993-05-10 | 1998-06-25 | 科研製薬株式会社 | アゾリルアミン誘導体 |
| US5601839A (en) | 1995-04-26 | 1997-02-11 | Theratech, Inc. | Triacetin as a penetration enhancer for transdermal delivery of a basic drug |
| US5696105A (en) * | 1996-03-14 | 1997-12-09 | Hackler; Walter A. | Antifungal nail composition |
| JPH1059847A (ja) | 1996-08-22 | 1998-03-03 | Sansho Seiyaku Co Ltd | 抗真菌剤 |
| US5993787A (en) * | 1996-09-13 | 1999-11-30 | Johnson & Johnson Consumer Products, Inc. | Composition base for topical therapeutic and cosmetic preparations |
| DE60042453D1 (de) * | 1999-07-28 | 2009-08-06 | Kaken Pharma Co Ltd | Verfahren zum nachweis pathogener mikroorganismen und antimikrobieller mittel, verfahren zum nachweis der arzneimittelwirkung antimikrobieller mittel und antimikrobielle mittel |
| BR0111718A (pt) * | 2000-06-16 | 2003-09-09 | Hercules Inc | Peptìdeos quimicamente modificados, composições e métodos de produção e uso |
| US6676953B2 (en) * | 2001-01-26 | 2004-01-13 | Don L. Hexamer | Antifungal composition and method for human nails |
| US6585963B1 (en) * | 2001-02-15 | 2003-07-01 | Watson Pharmaceuticals, Inc. | Nail compositions and methods of administering same |
-
2007
- 2007-12-28 CA CA2673976A patent/CA2673976C/en active Active
- 2007-12-28 PT PT07860506T patent/PT2116243E/pt unknown
- 2007-12-28 WO PCT/JP2007/075303 patent/WO2008081940A1/ja not_active Ceased
- 2007-12-28 EP EP07860506A patent/EP2116243B1/de active Active
- 2007-12-28 AT AT07860506T patent/ATE482703T1/de not_active IP Right Cessation
- 2007-12-28 JP JP2008552190A patent/JP5372523B2/ja active Active
- 2007-12-28 DE DE602007009574T patent/DE602007009574D1/de active Active
- 2007-12-28 US US12/521,483 patent/US8889155B2/en active Active
- 2007-12-28 ES ES07860506T patent/ES2350806T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2350806T3 (es) | 2011-01-27 |
| US8889155B2 (en) | 2014-11-18 |
| DE602007009574D1 (de) | 2010-11-11 |
| PT2116243E (pt) | 2010-10-26 |
| EP2116243B1 (de) | 2010-09-29 |
| JPWO2008081940A1 (ja) | 2010-04-30 |
| EP2116243A1 (de) | 2009-11-11 |
| EP2116243A4 (de) | 2009-12-23 |
| CA2673976C (en) | 2015-02-17 |
| JP5372523B2 (ja) | 2013-12-18 |
| US20100317695A1 (en) | 2010-12-16 |
| CA2673976A1 (en) | 2008-07-10 |
| WO2008081940A1 (ja) | 2008-07-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |