ATE482723T1 - Halbfeste mukoadhäsive formulierungen - Google Patents
Halbfeste mukoadhäsive formulierungenInfo
- Publication number
- ATE482723T1 ATE482723T1 AT04742064T AT04742064T ATE482723T1 AT E482723 T1 ATE482723 T1 AT E482723T1 AT 04742064 T AT04742064 T AT 04742064T AT 04742064 T AT04742064 T AT 04742064T AT E482723 T1 ATE482723 T1 AT E482723T1
- Authority
- AT
- Austria
- Prior art keywords
- semi
- mucoadhesive formulations
- solid
- solid mucoadhesive
- formulations
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000003232 mucoadhesive effect Effects 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title 1
- 241000282414 Homo sapiens Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000000227 bioadhesive Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Inorganic Chemistry (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Adhesive Tapes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200301672A ES2237298B1 (es) | 2003-07-16 | 2003-07-16 | Formulaciones mucoadhesivas semisolidas. |
| PCT/ES2004/000336 WO2005007194A1 (es) | 2003-07-16 | 2004-07-16 | Formulaciones mucoadhesivas semisólidas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE482723T1 true ATE482723T1 (de) | 2010-10-15 |
Family
ID=34072910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04742064T ATE482723T1 (de) | 2003-07-16 | 2004-07-16 | Halbfeste mukoadhäsive formulierungen |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8663688B2 (de) |
| EP (2) | EP1652535B1 (de) |
| JP (1) | JP4891765B2 (de) |
| AT (1) | ATE482723T1 (de) |
| CY (1) | CY1110954T1 (de) |
| DE (1) | DE602004029369D1 (de) |
| DK (1) | DK1652535T3 (de) |
| ES (2) | ES2237298B1 (de) |
| HR (1) | HRP20100635T1 (de) |
| PL (1) | PL1652535T3 (de) |
| PT (1) | PT1652535E (de) |
| SI (1) | SI1652535T1 (de) |
| WO (1) | WO2005007194A1 (de) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2237298B1 (es) | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
| AU2004274000B2 (en) | 2003-09-19 | 2009-07-30 | Drugtech Corporation | Pharmaceutical delivery system |
| CN101232869B (zh) * | 2005-06-16 | 2016-03-02 | 沃纳奇尔科特有限责任公司 | 局部给药的凝胶组合物 |
| EP1904028A1 (de) * | 2005-06-16 | 2008-04-02 | Warner Chilcott Company Inc. | Östrogenzusammensetzungen zur vaginalen verabreichung |
| EP1896078A1 (de) * | 2005-06-16 | 2008-03-12 | Warner Chilcott Company, Inc. | Östrogenzusammensetzungen zur vaginalen verabreichung |
| MX2008001687A (es) * | 2005-08-12 | 2008-02-19 | Drugtech Corp | Composiciones de estrogenos y metodos terapeuticos de uso. |
| WO2007085020A2 (en) * | 2006-01-20 | 2007-07-26 | Pear Tree Pharmaceuticals, Inc. | Method of treating atrophic vaginitis |
| LT2018164T (lt) * | 2006-05-12 | 2017-07-10 | Christian Noe | Vaistų derinių, apimančių priešgrybelinius agentus, naudojimas |
| BRPI0711525A2 (pt) * | 2006-06-02 | 2011-11-01 | Pear Tree Women S Health Care | composição farmacêutica e método para tratar sintomas de vaginite atrófica |
| WO2008005783A2 (en) * | 2006-06-30 | 2008-01-10 | Drugtech Corporation | Treatment of non- infectious inflammatory vulvovaginitis with a bioadhesive clindamycin composition |
| ES2310968B1 (es) * | 2007-06-25 | 2010-02-08 | Italfarmaco, S.A. | Uso de estriol en bajas dosis. |
| ES2344673B1 (es) * | 2008-08-07 | 2011-05-03 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral. |
| AU2009281998A1 (en) * | 2008-08-12 | 2010-02-18 | Novabay Pharmaceuticals, Inc. | Antimicrobial gel formulations |
| BRPI0803568B8 (pt) * | 2008-08-14 | 2021-05-25 | Biolab San Us Farm Ltda | composição mucoaderente |
| ES2344675B1 (es) * | 2008-12-19 | 2011-04-28 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular. |
| AU2011234492B2 (en) * | 2010-04-01 | 2014-02-27 | Palette Life Sciences AB | Thermogelling anaesthetic compositions |
| CN102293735B (zh) * | 2011-08-19 | 2013-05-01 | 辽宁万嘉医药科技有限公司 | 一种抗真菌咪唑类药物缓释凝胶和制备方法 |
| US8633178B2 (en) | 2011-11-23 | 2014-01-21 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| CN102600288B (zh) * | 2012-04-20 | 2014-03-05 | 广西源安堂药业有限公司 | 一种治疗阴道炎的复方黄松凝胶药物及其制备方法 |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10045935B2 (en) | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
| KR101358993B1 (ko) | 2012-09-05 | 2014-02-06 | 임혜선 | 네일 프린팅용 트랜스퍼 솔루션 및 이를 이용한 네일 프린팅 방법 |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| EP3145489A1 (de) | 2014-05-22 | 2017-03-29 | TherapeuticsMD, Inc. | Natürliche kombinierte hormonersatzformulierungen und therapien |
| RU2016141135A (ru) | 2014-07-29 | 2018-08-28 | Терапьютиксмд, Инк. | Трансдермальный крем |
| US20160175271A1 (en) * | 2014-12-19 | 2016-06-23 | Gavis Pharmaceuticals | Rectal suppository for ulcerative colitis |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| MX393613B (es) * | 2016-01-07 | 2025-03-24 | Viramal Ltd | Composiciones de gel para administracion transdermica para maximizar las concentraciones de farmaco en el estrato corneo y suero, y metodos de uso de las mismas. |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| WO2017173071A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| AU2019365255B2 (en) | 2018-10-26 | 2025-06-12 | Viramal Limited | Mucoadhesive gel composition |
| EP3659583B1 (de) | 2018-11-30 | 2023-06-07 | Viramal Limited | Verfahren zur herstellung eines geliermittels, das dadurch erhaltene geliermittel und verwendung dieses geliermittels |
| CN110151680A (zh) * | 2019-04-10 | 2019-08-23 | 重庆医药高等专科学校 | 雌三醇凝胶产品及制备方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0163696B1 (de) | 1983-11-14 | 1992-11-25 | Columbia Laboratories, Inc. | Verwendung eines bioadhesives |
| NZ222698A (en) | 1987-01-08 | 1990-02-26 | Squibb & Sons Inc | Bioadhesive suppository formulations comprising a medicament, water, a hydrocolloid and low melting point base |
| US5719197A (en) * | 1988-03-04 | 1998-02-17 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| DE69014081T2 (de) | 1989-10-31 | 1995-03-30 | Columbia Laboratories, Inc., Miami, Fla. | Mittel zur Feuchthaltung vaginalen Gewebes. |
| MC2204A1 (fr) | 1989-10-31 | 1992-11-26 | Columbia Lab Inc | Composition et methode d'humidification de tissus |
| US5543150A (en) | 1993-09-15 | 1996-08-06 | Columbia Laboratories, Inc. | Method of progesterone delivery and affect thereof |
| US5667492A (en) * | 1994-10-07 | 1997-09-16 | Columbia Laboratories, Inc. | Use and composition of an anti-sexually transmitted diseases formulation |
| AT408067B (de) | 1995-03-17 | 2001-08-27 | Gebro Pharma Gmbh | Pharmazeutische zusammensetzung zur topischen applizierung und verfahren zu ihrer herstellung |
| US5741525A (en) | 1995-10-24 | 1998-04-21 | Marshall University Research Corporation | Vaginal pharmaceutical hydrogen peroxide composition |
| AU714797B2 (en) | 1996-06-14 | 2000-01-13 | Mcneil-Ppc, Inc. | Moisture containing compositions that are spreadable onto and adherable to biomembranes, methods of making and use thereof |
| IT1284874B1 (it) | 1996-08-02 | 1998-05-22 | Farmigea Spa | Complessi bioadesivi di polycarbophil e farmaci antifungini o antiprotozoari azolici |
| US5942243A (en) | 1996-11-12 | 1999-08-24 | Polytherapeutics, Inc. | Mucoadhesive compositions for administration of biologically active agents to animal tissue |
| DE69739583D1 (de) | 1996-11-14 | 2009-10-29 | Lipomedica Ehf | Topische zusammensetzungen enthaltend als therapeutisch aktiven wirkstoff ein monoglycerid zur behandlung von schleimhautinfektionen |
| DE69819748T2 (de) | 1997-09-12 | 2004-09-30 | Columbia Laboratories (Bermuda) Ltd. | Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen |
| US6159491A (en) | 1999-02-12 | 2000-12-12 | Biovector Technologies, Inc. | Prolonged release bioadhesive vaginal gel dosage form |
| WO2000050078A1 (en) | 1999-02-26 | 2000-08-31 | Chiron Corporation | Use of bioadhesives and adjuvants for the mucosal delivery of antigens |
| SE522260C2 (sv) | 1999-10-01 | 2004-01-27 | Ericsson Telefon Ab L M | Metod, system och säkerhetsadapter för att exekvera säker dataöverföring i ett trådlöst nät |
| UA74168C2 (uk) | 1999-10-05 | 2005-11-15 | Коламбіа Леборетеріс (Бермуда) Лімітед | Лікування ендометріозу або безпліддя, або покращення плідності та застосування бета-адренергічного агоніста для виробництва лікарського засобу |
| WO2001028515A1 (en) * | 1999-10-22 | 2001-04-26 | Líf-Hlaup ehf. Bio-Gels Pharmaceuticals Inc. | Pharmaceutical composition for treatment of mucosal epithelial ulceration and/or erosion |
| ATE485837T1 (de) * | 2000-08-03 | 2010-11-15 | Antares Pharma Ipl Ag | Zusammensetzung zur transdermalen und/oder transmukosalen verabreichung von wirkstoffen, die ausreichende therapeutische spiegel garantiert |
| US20040092494A9 (en) * | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
| US7709026B2 (en) * | 2001-10-29 | 2010-05-04 | Columbia Laboratories, Inc. | Low concentration of peroxide for treating or preventing vaginal infections |
| US6967194B1 (en) * | 2002-09-18 | 2005-11-22 | Susan Matsuo | Bio-identical hormones and method of use |
| ES2237298B1 (es) | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
-
2003
- 2003-07-16 ES ES200301672A patent/ES2237298B1/es not_active Expired - Fee Related
-
2004
- 2004-07-16 US US10/565,062 patent/US8663688B2/en active Active
- 2004-07-16 SI SI200431522T patent/SI1652535T1/sl unknown
- 2004-07-16 JP JP2006519939A patent/JP4891765B2/ja not_active Expired - Lifetime
- 2004-07-16 EP EP04742064A patent/EP1652535B1/de not_active Expired - Lifetime
- 2004-07-16 AT AT04742064T patent/ATE482723T1/de active
- 2004-07-16 EP EP09161078A patent/EP2100612A3/de not_active Withdrawn
- 2004-07-16 WO PCT/ES2004/000336 patent/WO2005007194A1/es not_active Ceased
- 2004-07-16 DK DK04742064.1T patent/DK1652535T3/da active
- 2004-07-16 HR HR20100635T patent/HRP20100635T1/hr unknown
- 2004-07-16 PL PL04742064T patent/PL1652535T3/pl unknown
- 2004-07-16 ES ES04742064T patent/ES2353694T3/es not_active Expired - Lifetime
- 2004-07-16 DE DE602004029369T patent/DE602004029369D1/de not_active Expired - Lifetime
- 2004-07-16 PT PT04742064T patent/PT1652535E/pt unknown
-
2010
- 2010-11-25 CY CY20101101079T patent/CY1110954T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP4891765B2 (ja) | 2012-03-07 |
| WO2005007194A1 (es) | 2005-01-27 |
| EP1652535A1 (de) | 2006-05-03 |
| US8663688B2 (en) | 2014-03-04 |
| SI1652535T1 (sl) | 2010-12-31 |
| HRP20100635T1 (hr) | 2010-12-31 |
| ES2353694T3 (es) | 2011-03-04 |
| DE602004029369D1 (de) | 2010-11-11 |
| EP1652535B1 (de) | 2010-09-29 |
| EP2100612A2 (de) | 2009-09-16 |
| PT1652535E (pt) | 2010-11-18 |
| EP2100612A3 (de) | 2010-06-02 |
| CY1110954T1 (el) | 2015-06-11 |
| DK1652535T3 (da) | 2010-11-15 |
| US20060240111A1 (en) | 2006-10-26 |
| PL1652535T3 (pl) | 2011-03-31 |
| JP2007528864A (ja) | 2007-10-18 |
| ES2237298B1 (es) | 2006-11-01 |
| ES2237298A1 (es) | 2005-07-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE482723T1 (de) | Halbfeste mukoadhäsive formulierungen | |
| PT1446122E (pt) | Utilizacao de flibanserina no tratamento de disturbios de desejo sexual | |
| MA27888A1 (fr) | Inhibiteurs de la kinase p38 a base d'heterocycles a 5 chainons | |
| NO20053077D0 (no) | Terapeutiske formuleringer for behandling av beta-amyloid-relaterte sykdommer. | |
| WO2003014309A3 (en) | Interleukin-1 receptors in the treatment of diseases | |
| ATE407676T1 (de) | Topoisomerasehemmern zur behandlung von chirurgischen verklebungen | |
| NO20034056D0 (no) | Proliferative sykdommer | |
| IL181740A0 (en) | THERAPEUTIC AGENTS TARGETING THE NCca-atp CHANNEL AND METHODS OF USE THEREOF | |
| WO2006034048A3 (en) | Therapeutic agents targeting the ncca-atp channel and methods of use thereof | |
| TR200800691T2 (tr) | Miyelin kaybettiren hastalıkların ya da durumların tedavi yöntemi. | |
| CY1109666T1 (el) | Μεθοδος θεραπειας διαταραχων ξηροφθαλμιας και ραγοειδιτιδας | |
| IL172423A0 (en) | Novel formulations for opioid -based treatments of pain comprising substituted 1,4-di-piperidin-4-yl-piperazine derivatives | |
| DE602004014787D1 (de) | Anti-tumorale formulierungen mit defibrotid allein oder in kombination mit anderen antitumoralen mitteln | |
| BR0210632A (pt) | Tratamento de doença parasìtica | |
| SE0001916D0 (sv) | Novel formulation | |
| CY1106702T1 (el) | Χρηση ενος συνδυασμου μιας πουρινης και ενος παραγοντα δοτη μονοξειδιου του αζωτου για την προληψη ή την αγωγη γενετησιων δυσλειτουργιων | |
| DK1713438T3 (da) | Medicinsk sæbe | |
| BG101145A (bg) | Използване на /s/-аденозил-l-метионин /саме/ i неговите физиологично съвместими соли за лечение нареперфузионно увреждане, причинено от временна фокална исхемиа | |
| WO2002051404A8 (fr) | Compositions orales | |
| RU2000104127A (ru) | Штамм bacillus subtilis x-15, используемый для профилактики и лечения эндометритов у коров | |
| WO2004006900A3 (en) | Sulphydryl compounds in combination with sulphone or sulphnamide conpounds for use in microbial inflammatory diseases | |
| ITBO20000360A0 (it) | Apparecchiatura di elettrostimolazione del corpo umano . | |
| DE602004010353D1 (de) | Aktiviebare bioaktive implantierbare medizinische Vorrichtung. | |
| ES2159479A1 (es) | Nuevos indazoles como inhibidores de la ciclooxigenasa-ii | |
| WO2002083110A3 (en) | Animal model for evaluating analgesics |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1652535 Country of ref document: EP |