MA27888A1 - Inhibiteurs de la kinase p38 a base d'heterocycles a 5 chainons - Google Patents

Inhibiteurs de la kinase p38 a base d'heterocycles a 5 chainons

Info

Publication number
MA27888A1
MA27888A1 MA28678A MA28678A MA27888A1 MA 27888 A1 MA27888 A1 MA 27888A1 MA 28678 A MA28678 A MA 28678A MA 28678 A MA28678 A MA 28678A MA 27888 A1 MA27888 A1 MA 27888A1
Authority
MA
Morocco
Prior art keywords
kinase
kinase inhibitors
inhibitors based
heterocycles
chain
Prior art date
Application number
MA28678A
Other languages
English (en)
Inventor
Olga M Fryszman
Hengyuan Lang
Jiong Lan
Edcon Chang
Yunfeng Fang
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34108816&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA27888(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA27888A1 publication Critical patent/MA27888A1/fr

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    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
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Abstract

L'invention concerne des inhibiteurs de la kinase p38 à base d'hétérocycles à 5 chaînons. L'invention concerne en outre des inhibiteurs de la kinase p38, notamment de la kinase p38(alpha) et p38(bêta), à base de pyrazoles et d'imidazoles. L'invention concerne par ailleurs des compositions pharmaceutiques contenant ces composés, ainsi que des méthodes d'utilisation de ces composés et de ces compositions, notamment des méthodes visant à traiter, prévenir ou améliorer un ou plusieurs symptômes de maladies et de troubles à médiation par la kinase p38 comprenant, de façon non limitative, des maladies et des troubles inflammatoires.
MA28678A 2003-06-26 2005-12-21 Inhibiteurs de la kinase p38 a base d'heterocycles a 5 chainons MA27888A1 (fr)

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US48342803P 2003-06-26 2003-06-26
US49905403P 2003-08-29 2003-08-29
US56048104P 2004-04-07 2004-04-07

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MY158162A (en) 2016-09-15
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CA2526455C (fr) 2012-10-09
JP4838121B2 (ja) 2011-12-14
EP2298743A1 (fr) 2011-03-23
US7863314B2 (en) 2011-01-04
CY1113313T1 (el) 2016-04-13
JP2007521278A (ja) 2007-08-02
ATE517872T1 (de) 2011-08-15
US20130172352A1 (en) 2013-07-04

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