ATE486592T1 - Memantin für die behandlung von leichtem bis mittelschwerem morbus alzheimer - Google Patents

Memantin für die behandlung von leichtem bis mittelschwerem morbus alzheimer

Info

Publication number
ATE486592T1
ATE486592T1 AT05711256T AT05711256T ATE486592T1 AT E486592 T1 ATE486592 T1 AT E486592T1 AT 05711256 T AT05711256 T AT 05711256T AT 05711256 T AT05711256 T AT 05711256T AT E486592 T1 ATE486592 T1 AT E486592T1
Authority
AT
Austria
Prior art keywords
mild
disease
memantine
treatment
moderate alzheimer
Prior art date
Application number
AT05711256T
Other languages
English (en)
Inventor
Scott Mcdonald
Ivan Gergel
Albrecht Stoeffler
Hans-Joerg Moebius
Yvonne Wirth
Steven Potkin
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34798833&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE486592(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Application granted granted Critical
Publication of ATE486592T1 publication Critical patent/ATE486592T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Radiation-Therapy Devices (AREA)
AT05711256T 2004-01-05 2005-01-05 Memantin für die behandlung von leichtem bis mittelschwerem morbus alzheimer ATE486592T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53455304P 2004-01-05 2004-01-05
US54217604P 2004-02-04 2004-02-04
PCT/US2005/000145 WO2005067908A2 (en) 2004-01-05 2005-01-05 Memantine for the treatment of mild and mild-to-moderate alzheimer’s disease

Publications (1)

Publication Number Publication Date
ATE486592T1 true ATE486592T1 (de) 2010-11-15

Family

ID=34798833

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05711256T ATE486592T1 (de) 2004-01-05 2005-01-05 Memantin für die behandlung von leichtem bis mittelschwerem morbus alzheimer

Country Status (17)

Country Link
US (2) US20060020042A1 (de)
EP (1) EP1703902B1 (de)
AT (1) ATE486592T1 (de)
AU (1) AU2005204358B2 (de)
CA (1) CA2551689A1 (de)
CY (1) CY1111359T1 (de)
DE (1) DE602005024511D1 (de)
DK (1) DK1703902T3 (de)
HR (1) HRP20110035T1 (de)
IL (1) IL176689A0 (de)
NZ (1) NZ548327A (de)
PL (1) PL1703902T3 (de)
PT (1) PT1703902E (de)
RS (1) RS51540B (de)
RU (1) RU2371173C2 (de)
SI (1) SI1703902T1 (de)
WO (1) WO2005067908A2 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
EP2243475B1 (de) 2005-04-06 2016-01-13 Adamas Pharmaceuticals, Inc. Kombination von Memantin und Donepezil zur Behandlung von Erkrankungen des ZNS
AU2006261082B2 (en) * 2005-06-22 2012-04-19 Boehringer Ingelheim International Gmbh Thienopyrimidines for pharmaceutical compositions
CN101466716A (zh) * 2006-04-07 2009-06-24 德维洛根股份公司 用于药物组合物的具有mnkl/mnk2抑制活性的噻吩并嘧啶
EP1889847A1 (de) * 2006-07-10 2008-02-20 DeveloGen Aktiengesellschaft Pyrrolopyrimidine zur pharmazeutischen Anwendung
KR20090041447A (ko) * 2006-08-21 2009-04-28 노파르티스 아게 알츠하이머 질환 진행에 대한 바이오마커
US20080182908A1 (en) * 2007-01-25 2008-07-31 Vinita Umashankar Vyas Pharmaceutical compositions comprising memantine
WO2009065596A2 (en) * 2007-11-22 2009-05-28 Develogen Aktiengesellschaft Use of mnk inhibitors for the treatment of alzheimer's disease
BRPI0918971A2 (pt) 2008-08-26 2015-12-01 Boehringer Ingelheim Int tienopirimidinas para composições farmacêuticas
CA2772797C (en) 2009-09-30 2018-09-25 Transtech Pharma, Inc. Substituted imidazole derivatives
TW201141872A (en) * 2010-02-26 2011-12-01 Boehringer Ingelheim Int Cycloalkyl containing thienopyrimidines for pharmaceutical compositions
UY33241A (es) * 2010-02-26 2011-09-30 Boehringer Ingelheim Int ?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?.
UY33245A (es) * 2010-02-26 2011-09-30 Boehringer Ingelheim Int Tienopirimidinas que contienen un grupo alquilo sustituido para composiciones farmacéuticas
US20140350380A1 (en) * 2011-09-19 2014-11-27 The Feinstein Institute For Medical Research Identification and uses of brain activity networks
JP5404750B2 (ja) * 2011-11-22 2014-02-05 シャープ株式会社 認知症ケア支援方法、認知症情報出力装置、認知症ケア支援システム、及びコンピュータプログラム
FR2983732B1 (fr) * 2011-12-09 2013-11-22 Servier Lab Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}pharmaceutiques qui la contiennent
WO2014015047A1 (en) 2012-07-17 2014-01-23 The General Hospital Corporation Compositions and methods to treat neurodegenerative diseases
US9717710B2 (en) 2012-10-05 2017-08-01 Vtv Therapeutics Llc Treatment of mild and moderate Alzheimer's disease
EP3019865A4 (de) * 2013-07-12 2017-04-05 Immuneering Corporation Systeme, verfahren und umgebung zur automatisierten überprüfung von genomdaten zur identifikation einer herunterregulierten und/oder unregulierten genexpression als zeichen einer erkrankung oder eines leidens
WO2019190823A1 (en) 2018-03-28 2019-10-03 Vtv Therapeutics Llc Pharmaceutically acceptable salts of [3-(4- {2-butyl-1-[4-(4-chlorophenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
WO2019190822A1 (en) 2018-03-28 2019-10-03 Vtv Therapeutics Llc Crystalline forms of [3-(4- {2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
JP7402225B2 (ja) 2018-05-11 2023-12-20 ロード アイランド ホスピタル ヌクレオシド系逆転写酵素阻害剤を用いて関節障害を処置するための組成物および方法
JP7464591B2 (ja) 2018-10-10 2024-04-09 ブイティーブイ・セラピューティクス・エルエルシー ［３－（４－｛２－ブチル－１－［４－（４－クロロ－フェノキシ）－フェニル］－１ｈ－イミダゾール－４－イル｝－フェノキシ）－プロピル］－ジエチル－アミンの代謝産物
AU2020211600A1 (en) 2019-01-25 2021-07-22 Brown University Compositions and methods for treating, preventing or reversing age-associated inflammation and disorders
US20210002650A1 (en) * 2019-07-03 2021-01-07 University Of Virginia Patent Foundation Compositions and methods for treating alzheimer's disease
KR102271305B1 (ko) * 2020-05-21 2021-06-30 주식회사 아리바이오 치매 예방 및 치료용 조성물
EP4190319A4 (de) 2020-07-29 2024-05-01 Novamedica Limited Liability Company Pharmazeutische zusammensetzung mit memantin und citicolin
KR102272907B1 (ko) * 2020-11-05 2021-07-05 주식회사 아리바이오 치매 예방 및 치료용 조성물
CN120225200A (zh) * 2022-06-24 2025-06-27 阿丽派欧株式会社 用于预防和治疗神经退行性疾病的组合物和方法
EP4547254A1 (de) * 2022-06-29 2025-05-07 Aribio Co., Ltd Zusammensetzung zur prävention und behandlung neurodegenerativer erkrankungen

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA974518A (en) * 1972-04-20 1975-09-16 Merz And Co. Procedure for the manufacture of 1,3,5 trisubstituted adamantan compounds
DE2856393C2 (de) * 1978-12-27 1983-04-28 Merz + Co GmbH & Co, 6000 Frankfurt Arzneimittel zur Behandlung von Morbus Parkinson
US5334618A (en) * 1991-04-04 1994-08-02 The Children's Medical Center Corporation Method of preventing NMDA receptor-mediated neuronal damage
US5506231A (en) * 1989-03-31 1996-04-09 The Children's Medical Center Corporation Treatment of aids dementia, myelopathy and blindness
ES2059602T3 (es) * 1989-04-14 1994-11-16 Merz & Co Gmbh & Co Uso de derivados de adamantano para la prevencion y tratamiento de isquemia cerebral.
US5614560A (en) * 1991-04-04 1997-03-25 Children's Medical Center Corporation Method of preventing NMDA receptor-mediated neuronal damage
US5958919A (en) * 1996-09-20 1999-09-28 Washington University Treatment of presymptomatic alzheimer's disease to prevent neuronal degeneration
ATE240936T1 (de) * 1997-06-30 2003-06-15 Merz & Co Gmbh & Co 1-amino-alkylcyclohexane als nmda-rezeptor- antagonisten
GB9806513D0 (en) * 1998-03-26 1998-05-27 Phytopharm Ltd Membrane-bound receptors
US20040102525A1 (en) * 2002-05-22 2004-05-27 Kozachuk Walter E. Compositions and methods of treating neurological disease and providing neuroprotection
ATE414519T1 (de) * 2002-05-31 2008-12-15 Lundbeck & Co As H Kombination aus einem nmda-antagonist und acetylcholinesterase-hemmern zur behandlung der alzheimer-krankheit
EP2260839A3 (de) * 2002-10-24 2012-05-02 Merz Pharma GmbH & Co. KGaA Kombinationstherapie unter Verwendung von 1-Aminocyclohexan Derivaten und Acetylcholinesterase Inhibitoren
EP1603548A4 (de) * 2003-02-05 2007-10-10 Myriad Genetics Inc Verfahren und zusammensetzung zur behandlung neurodegenerativer erkrankungen

Also Published As

Publication number Publication date
SI1703902T1 (sl) 2011-02-28
US20100048726A1 (en) 2010-02-25
WO2005067908A3 (en) 2005-11-10
RU2007129842A (ru) 2009-02-10
RU2371173C2 (ru) 2009-10-27
PL1703902T3 (pl) 2011-04-29
EP1703902B1 (de) 2010-11-03
HRP20110035T1 (hr) 2011-02-28
DE602005024511D1 (de) 2010-12-16
DK1703902T3 (da) 2011-02-14
CA2551689A1 (en) 2005-07-28
RS51540B (sr) 2011-06-30
AU2005204358A1 (en) 2005-07-28
CY1111359T1 (el) 2015-08-05
AU2005204358B2 (en) 2008-09-04
WO2005067908A2 (en) 2005-07-28
NZ548327A (en) 2009-06-26
EP1703902A2 (de) 2006-09-27
IL176689A0 (en) 2006-10-31
PT1703902E (pt) 2010-11-17
US20060020042A1 (en) 2006-01-26

Similar Documents

Publication Publication Date Title
ATE486592T1 (de) Memantin für die behandlung von leichtem bis mittelschwerem morbus alzheimer
EA200700427A1 (ru) Предупреждение и лечение синуклеинопатических и амилоидогенных заболеваний
ECSP055719A (es) Compuestos de tiazol para el tratamiento de trastornos neurodegenerativos
ATE409176T1 (de) 1-phenylalkancarbonsäurederivate zur behandlung neurodegenerativer erkrankungen
DK1346041T3 (da) Terapeutiske midler og fremgangsmåder til anvendelse deraf til behandling af en amyloidogen sygdom
WO2005076819A3 (en) Chlorite in the treatment of neurodegenerative disease
EA200700708A1 (ru) Мемантин для лечения расстройств поведения детского возраста
JP2018502884A5 (de)
ATE371724T1 (de) Behandlung neurodegenerativer krankheiten
BR0306855A (pt) Método para o tratamento de distúrbios cognitivos
EA200501479A1 (ru) Ifn-бета в отдельности или в комбинации с другими лекарственными средствами для лечения болезни альцгеймера и нарушений, связанных с деменцией
ATE383853T1 (de) Arylessigsäuren und verwandte verbindungen zur behandlung von alzheimer-krankheit
DE602004023762D1 (de) Für die behandlung von alzheimer-krankheit und ähnlichen leiden geeignete 1-alkyl-3-thiosubstituierte indol-2-alkinsäuren
ATE392471T1 (de) Behandlung neurodegenerativer krankheiten durch verwendung von scd4-inhibitoren
MX2024000701A (es) Metodos de tratamiento de la enfermedad de alzheimer.
CY1109666T1 (el) Μεθοδος θεραπειας διαταραχων ξηροφθαλμιας και ραγοειδιτιδας
GT200400231A (es) Compuestos de sulfoniltetrahidro-3h-benzo(e)indol-8-amina como ligandos de la 5-hidroxitriptamina-6.
ATE464048T1 (de) Behandlung von alzheimer-krankheit und verwandten zuständen
ATE494903T1 (de) Verwendung von slurp-1 zur behandlung von krankheiten, die durch störungen der acetylcholinerezeptoren ausgelöst werden
DE602004024871D1 (de) Polyamin-verbindungen zur behandlung von chemokin-rezeptor-vermittelten krankheiten
SG153698A1 (en) Composition and method for prevention and treatment of alzheimeræs disease
MXPA05013975A (es) Tratamiento de enfermedades asociadas con amiloide y epileptogenesis.
ATE495750T1 (de) Sulfatide zur behandlung von autoimmunkrankheiten
BR0308753A (pt) Método para produzir pseudo-ilhotas
RU2002112569A (ru) Способ лечения детей с посттравматическим арахноидитом радоновыми ваннами в комплексе с электромагнитным полем низкой частоты от аппарата "ИНФИТО"

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1703902

Country of ref document: EP