DK1703902T3 - Memantin til behandling af mild til moderat Alzheimer's sygdom - Google Patents
Memantin til behandling af mild til moderat Alzheimer's sygdomInfo
- Publication number
- DK1703902T3 DK1703902T3 DK05711256.7T DK05711256T DK1703902T3 DK 1703902 T3 DK1703902 T3 DK 1703902T3 DK 05711256 T DK05711256 T DK 05711256T DK 1703902 T3 DK1703902 T3 DK 1703902T3
- Authority
- DK
- Denmark
- Prior art keywords
- mild
- disease
- memantine
- treatment
- moderate alzheimer
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 3
- BUGYDGFZZOZRHP-UHFFFAOYSA-N memantine Chemical compound C1C(C2)CC3(C)CC1(C)CC2(N)C3 BUGYDGFZZOZRHP-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004640 memantine Drugs 0.000 title abstract 2
- 210000004556 brain Anatomy 0.000 abstract 1
- 230000001054 cortical effect Effects 0.000 abstract 1
- 230000004153 glucose metabolism Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000002739 subcortical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Radiation-Therapy Devices (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53455304P | 2004-01-05 | 2004-01-05 | |
| US54217604P | 2004-02-04 | 2004-02-04 | |
| PCT/US2005/000145 WO2005067908A2 (en) | 2004-01-05 | 2005-01-05 | Memantine for the treatment of mild and mild-to-moderate alzheimer’s disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1703902T3 true DK1703902T3 (da) | 2011-02-14 |
Family
ID=34798833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05711256.7T DK1703902T3 (da) | 2004-01-05 | 2005-01-05 | Memantin til behandling af mild til moderat Alzheimer's sygdom |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20060020042A1 (da) |
| EP (1) | EP1703902B1 (da) |
| AT (1) | ATE486592T1 (da) |
| AU (1) | AU2005204358B2 (da) |
| CA (1) | CA2551689A1 (da) |
| CY (1) | CY1111359T1 (da) |
| DE (1) | DE602005024511D1 (da) |
| DK (1) | DK1703902T3 (da) |
| HR (1) | HRP20110035T1 (da) |
| IL (1) | IL176689A0 (da) |
| NZ (1) | NZ548327A (da) |
| PL (1) | PL1703902T3 (da) |
| PT (1) | PT1703902E (da) |
| RS (1) | RS51540B (da) |
| RU (1) | RU2371173C2 (da) |
| SI (1) | SI1703902T1 (da) |
| WO (1) | WO2005067908A2 (da) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7619007B2 (en) | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
| US8058291B2 (en) | 2005-04-06 | 2011-11-15 | Adamas Pharmaceuticals, Inc. | Methods and compositions for the treatment of CNS-related conditions |
| AU2006261082B2 (en) * | 2005-06-22 | 2012-04-19 | Boehringer Ingelheim International Gmbh | Thienopyrimidines for pharmaceutical compositions |
| CA2651898A1 (en) * | 2006-04-07 | 2007-10-18 | Develogen Aktiengesellschaft | Thienopyrimidines having mnk1/mnk2 inhibiting activity for pharmaceutical compositions |
| EP1889847A1 (en) * | 2006-07-10 | 2008-02-20 | DeveloGen Aktiengesellschaft | Pyrrolopyrimidines for pharmaceutical compositions |
| EP2056876A1 (en) * | 2006-08-21 | 2009-05-13 | Novartis AG | Biomarkers for alzheimer's disease progression |
| US20080182908A1 (en) * | 2007-01-25 | 2008-07-31 | Vinita Umashankar Vyas | Pharmaceutical compositions comprising memantine |
| CA2706203A1 (en) * | 2007-11-22 | 2009-05-28 | Boehringer Ingelheim International Gmbh | Use of mnk inhibitors for the treatment of alzheimer's disease |
| BRPI0918971A2 (pt) | 2008-08-26 | 2015-12-01 | Boehringer Ingelheim Int | tienopirimidinas para composições farmacêuticas |
| CA2772797C (en) | 2009-09-30 | 2018-09-25 | Transtech Pharma, Inc. | Substituted imidazole derivatives |
| ES2562959T3 (es) * | 2010-02-26 | 2016-03-09 | Evotec International Gmbh | Tienopirimidinas que contienen un grupo alquilo sustituido para composiciones farmacéuticas |
| MX2012009735A (es) * | 2010-02-26 | 2012-09-12 | Boehringer Ingelheim Int | 4-[cicloalquiloxi (hetero) arilamino] tieno [2,3-d] pirimidinas que tienen actividad inhibitoria de mnk1/mnk2 para composiciones farmaceuticas. |
| UY33241A (es) * | 2010-02-26 | 2011-09-30 | Boehringer Ingelheim Int | ?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?. |
| US20140350380A1 (en) * | 2011-09-19 | 2014-11-27 | The Feinstein Institute For Medical Research | Identification and uses of brain activity networks |
| JP5404750B2 (ja) * | 2011-11-22 | 2014-02-05 | シャープ株式会社 | 認知症ケア支援方法、認知症情報出力装置、認知症ケア支援システム、及びコンピュータプログラム |
| FR2983732B1 (fr) * | 2011-12-09 | 2013-11-22 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}pharmaceutiques qui la contiennent |
| WO2014015047A1 (en) | 2012-07-17 | 2014-01-23 | The General Hospital Corporation | Compositions and methods to treat neurodegenerative diseases |
| KR20150064743A (ko) | 2012-10-05 | 2015-06-11 | 트랜스테크 파르마 엘엘씨 | 경도 및 중등도 알츠하이머 병의 치료 |
| WO2015006643A2 (en) * | 2013-07-12 | 2015-01-15 | Immuneering Corporation | Systems, methods, and environment for automated review of genomic data to identify downregulated and/or upregulated gene expression indicative of a disease or condition |
| WO2019190823A1 (en) | 2018-03-28 | 2019-10-03 | Vtv Therapeutics Llc | Pharmaceutically acceptable salts of [3-(4- {2-butyl-1-[4-(4-chlorophenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine |
| WO2019190822A1 (en) | 2018-03-28 | 2019-10-03 | Vtv Therapeutics Llc | Crystalline forms of [3-(4- {2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine |
| JP7402225B2 (ja) | 2018-05-11 | 2023-12-20 | ロード アイランド ホスピタル | ヌクレオシド系逆転写酵素阻害剤を用いて関節障害を処置するための組成物および方法 |
| JP7464591B2 (ja) | 2018-10-10 | 2024-04-09 | ブイティーブイ・セラピューティクス・エルエルシー | [3-(4-{2-ブチル-1-[4-(4-クロロ-フェノキシ)-フェニル]-1h-イミダゾール-4-イル}-フェノキシ)-プロピル]-ジエチル-アミンの代謝産物 |
| MX2021008751A (es) | 2019-01-25 | 2021-11-12 | Univ Brown | Composiciones y metodos para tratar, prevenir o revertir la inflamacion y los trastornos asociados a la edad. |
| US20210002650A1 (en) * | 2019-07-03 | 2021-01-07 | University Of Virginia Patent Foundation | Compositions and methods for treating alzheimer's disease |
| KR102271305B1 (ko) * | 2020-05-21 | 2021-06-30 | 주식회사 아리바이오 | 치매 예방 및 치료용 조성물 |
| EP4190319A4 (en) | 2020-07-29 | 2024-05-01 | Novamedica Limited Liability Company | Pharmaceutical composition comprising memantine and citicoline |
| KR102272907B1 (ko) * | 2020-11-05 | 2021-07-05 | 주식회사 아리바이오 | 치매 예방 및 치료용 조성물 |
| JP2025520781A (ja) * | 2022-06-24 | 2025-07-03 | アリバイオ カンパニー リミテッド | 神経変性疾患の予防及び治療のための組成物及び方法 |
| WO2024003784A1 (en) * | 2022-06-29 | 2024-01-04 | Aribio Co., Ltd. | Composition for preventing and treating neurodegenerative diseases |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7305644A (da) * | 1972-04-20 | 1973-10-23 | ||
| DE2856393C2 (de) * | 1978-12-27 | 1983-04-28 | Merz + Co GmbH & Co, 6000 Frankfurt | Arzneimittel zur Behandlung von Morbus Parkinson |
| US5506231A (en) * | 1989-03-31 | 1996-04-09 | The Children's Medical Center Corporation | Treatment of aids dementia, myelopathy and blindness |
| US5334618A (en) * | 1991-04-04 | 1994-08-02 | The Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
| DE10299048I2 (de) * | 1989-04-14 | 2006-07-13 | Merz Pharma Gmbh & Co Kgaa | Verwendung von Adamantan-Derivaten zur Pr{vention und Behandlung der cerebralen Isch{mie |
| US5614560A (en) * | 1991-04-04 | 1997-03-25 | Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
| US5958919A (en) * | 1996-09-20 | 1999-09-28 | Washington University | Treatment of presymptomatic alzheimer's disease to prevent neuronal degeneration |
| UA61962C2 (uk) * | 1997-06-30 | 2003-12-15 | Мерц Фарма Гмбх Унд Ко. Кгаа | Сполука 1-аміноалкілциклогексану, фармацевтична композиція на її основі та спосіб лікування |
| GB9806513D0 (en) * | 1998-03-26 | 1998-05-27 | Phytopharm Ltd | Membrane-bound receptors |
| US20040102525A1 (en) * | 2002-05-22 | 2004-05-27 | Kozachuk Walter E. | Compositions and methods of treating neurological disease and providing neuroprotection |
| EP1509232B1 (en) * | 2002-05-31 | 2008-11-19 | H. Lundbeck A/S | A combination of an nmda-antagonist and acetylcholine esterase inhibitors for the treatment of alzheimer's disease |
| CN100339070C (zh) * | 2002-10-24 | 2007-09-26 | 莫茨药物股份两合公司 | 包含1-氨基环己烷衍生物类和乙酰胆碱酯酶抑制剂类的药物组合物 |
| EP1603548A4 (en) * | 2003-02-05 | 2007-10-10 | Myriad Genetics Inc | METHOD AND COMPOSITION FOR THE TREATMENT OF NEURODEEGENERATIVE DISEASES |
-
2005
- 2005-01-05 SI SI200531209T patent/SI1703902T1/sl unknown
- 2005-01-05 CA CA002551689A patent/CA2551689A1/en not_active Abandoned
- 2005-01-05 PT PT05711256T patent/PT1703902E/pt unknown
- 2005-01-05 AT AT05711256T patent/ATE486592T1/de active
- 2005-01-05 RU RU2007129842/14A patent/RU2371173C2/ru active
- 2005-01-05 US US11/030,584 patent/US20060020042A1/en not_active Abandoned
- 2005-01-05 WO PCT/US2005/000145 patent/WO2005067908A2/en not_active Ceased
- 2005-01-05 NZ NZ548327A patent/NZ548327A/en unknown
- 2005-01-05 DE DE602005024511T patent/DE602005024511D1/de not_active Expired - Lifetime
- 2005-01-05 AU AU2005204358A patent/AU2005204358B2/en not_active Revoked
- 2005-01-05 DK DK05711256.7T patent/DK1703902T3/da active
- 2005-01-05 HR HR20110035T patent/HRP20110035T1/hr unknown
- 2005-01-05 PL PL05711256T patent/PL1703902T3/pl unknown
- 2005-01-05 EP EP05711256A patent/EP1703902B1/en not_active Revoked
- 2005-01-05 RS RSP-2010/0561A patent/RS51540B/sr unknown
-
2006
- 2006-07-03 IL IL176689A patent/IL176689A0/en unknown
-
2009
- 2009-10-29 US US12/608,046 patent/US20100048726A1/en not_active Abandoned
-
2011
- 2011-01-04 CY CY20111100011T patent/CY1111359T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2371173C2 (ru) | 2009-10-27 |
| RS51540B (sr) | 2011-06-30 |
| PT1703902E (pt) | 2010-11-17 |
| US20060020042A1 (en) | 2006-01-26 |
| US20100048726A1 (en) | 2010-02-25 |
| PL1703902T3 (pl) | 2011-04-29 |
| CA2551689A1 (en) | 2005-07-28 |
| AU2005204358A1 (en) | 2005-07-28 |
| HRP20110035T1 (hr) | 2011-02-28 |
| AU2005204358B2 (en) | 2008-09-04 |
| EP1703902B1 (en) | 2010-11-03 |
| NZ548327A (en) | 2009-06-26 |
| CY1111359T1 (el) | 2015-08-05 |
| WO2005067908A3 (en) | 2005-11-10 |
| SI1703902T1 (sl) | 2011-02-28 |
| RU2007129842A (ru) | 2009-02-10 |
| IL176689A0 (en) | 2006-10-31 |
| WO2005067908A2 (en) | 2005-07-28 |
| EP1703902A2 (en) | 2006-09-27 |
| DE602005024511D1 (de) | 2010-12-16 |
| ATE486592T1 (de) | 2010-11-15 |
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