BR0311375A - Composição farmacêutica, uso da mesma, e, método para o tratamento de demência ou dano cognitivo suave em um mamìfero - Google Patents
Composição farmacêutica, uso da mesma, e, método para o tratamento de demência ou dano cognitivo suave em um mamìferoInfo
- Publication number
- BR0311375A BR0311375A BR0311375-2A BR0311375A BR0311375A BR 0311375 A BR0311375 A BR 0311375A BR 0311375 A BR0311375 A BR 0311375A BR 0311375 A BR0311375 A BR 0311375A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- mammal
- cognitive impairment
- mild cognitive
- treating dementia
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 206010012289 Dementia Diseases 0.000 title 1
- 241000124008 Mammalia Species 0.000 title 1
- 208000010877 cognitive disease Diseases 0.000 title 1
- 208000027061 mild cognitive impairment Diseases 0.000 title 1
- 229940100578 Acetylcholinesterase inhibitor Drugs 0.000 abstract 1
- 239000000544 cholinesterase inhibitor Substances 0.000 abstract 1
- 239000003703 n methyl dextro aspartic acid receptor blocking agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"COMPOSIçãO FARMACêUTICA, USO DA MESMA, E, MéTODO PARA O TRATAMENTO DE DEMêNCIA OU DANO COGNITIVO SUAVE EM UM MAMìFERO". Uma composição farmacêutica compreendendo: (a) uma quantidade efetiva de um ou mais inibidores de acetilcolinesterase ou de um seu sal farmaceuticamente aceitável e (b) uma quantidade efetiva de um ou mais antagonistas de NMDA.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38446702P | 2002-05-31 | 2002-05-31 | |
| DKPA200200844 | 2002-05-31 | ||
| PCT/DK2003/000342 WO2003101458A1 (en) | 2002-05-31 | 2003-05-22 | A combination of an nmda-antagonist and acetylcholine esterase inhibitors for the treatment of alzheimer's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0311375A true BR0311375A (pt) | 2005-03-15 |
Family
ID=29713304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0311375-2A BR0311375A (pt) | 2002-05-31 | 2003-05-22 | Composição farmacêutica, uso da mesma, e, método para o tratamento de demência ou dano cognitivo suave em um mamìfero |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1509232B1 (pt) |
| JP (1) | JP2005528431A (pt) |
| AT (1) | ATE414519T1 (pt) |
| AU (1) | AU2003227516B2 (pt) |
| BR (1) | BR0311375A (pt) |
| CY (1) | CY1108725T1 (pt) |
| DE (1) | DE60324788D1 (pt) |
| DK (1) | DK1509232T3 (pt) |
| ES (1) | ES2314200T3 (pt) |
| IL (1) | IL165255A0 (pt) |
| MX (1) | MXPA04011762A (pt) |
| NO (1) | NO332754B1 (pt) |
| NZ (1) | NZ536603A (pt) |
| PL (1) | PL373903A1 (pt) |
| PT (1) | PT1509232E (pt) |
| SI (1) | SI1509232T1 (pt) |
| WO (1) | WO2003101458A1 (pt) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100777904B1 (ko) * | 2002-10-24 | 2007-11-28 | 메르츠 파마 게엠베하 운트 코. 카가아 | 1-아미노시클로헥산 유도체 및 아세틸콜린에스테라제 저해제를 포함하는 약학적 제품 및 이를 이용한 복합 치료 |
| ATE486592T1 (de) * | 2004-01-05 | 2010-11-15 | Merz Pharma Gmbh & Co Kgaa | Memantin für die behandlung von leichtem bis mittelschwerem morbus alzheimer |
| AU2005205882A1 (en) * | 2004-01-22 | 2005-08-04 | Neurosearch A/S | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an N-methyl-D-aspartate (NMDA) receptors antagonist |
| TW200531680A (en) * | 2004-03-03 | 2005-10-01 | Merz Pharma Gmbh & Co Kgaa | Therapy using 1-aminocyclohexane derivatives for the treatment of behavioral disorders associated with alzheimer's disease |
| EP1740172A4 (en) * | 2004-03-19 | 2007-10-10 | Axonyx Inc | ACETYLCHOLINESTERASE INHIBITORS AND N-METHYL-D-ASPARTATE ANTAGONISTS FOR THE TREATMENT OF COGNITIVE DISORDER |
| EP1827385B1 (en) * | 2004-11-23 | 2013-03-27 | Adamas Pharmaceuticals, Inc. | Pharmaceutical composition comprising memantine in an extended dosage release form for use in the treatment of dementias |
| US7619007B2 (en) | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
| JP5666087B2 (ja) | 2005-04-06 | 2015-02-12 | アダマス・ファーマシューティカルズ・インコーポレーテッド | Cns関連疾患の治療のための方法及び組成物 |
| KR101213345B1 (ko) | 2005-04-28 | 2012-12-17 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 항치매약을 함유하는 조성물 |
| TWI389709B (zh) * | 2005-12-01 | 2013-03-21 | Novartis Ag | 經皮治療系統 |
| EP2089383B1 (en) | 2006-11-09 | 2015-09-16 | Probiodrug AG | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
| US9126987B2 (en) | 2006-11-30 | 2015-09-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| AU2008220785B2 (en) | 2007-03-01 | 2013-02-21 | Vivoryon Therapeutics N.V. | New use of glutaminyl cyclase inhibitors |
| JP5667440B2 (ja) | 2007-04-18 | 2015-02-12 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体 |
| JP5934645B2 (ja) | 2009-09-11 | 2016-06-15 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのヘテロ環式誘導体 |
| RU2414856C1 (ru) * | 2009-12-01 | 2011-03-27 | Государственное образовательное учреждение высшего профессионального образования Первый Московский медицинский университет имени И.М.Сеченова Министерства здравоохранения и социального развития Российской Федерации (ГОУ ВПО Первый МГМУ им. И.М.Сеченова Минздравсоцразвития России) | Способ определения эффективности противодементной терапии болезни альцгеймера |
| MX365650B (es) | 2009-12-02 | 2019-06-10 | Adamas Pharmaceuticals Inc | Composiciones de amantadina y metodos para su uso. |
| EA202092673A3 (ru) | 2010-02-09 | 2021-05-31 | Дзе Джонс Хопкинс Юниверсити | Способы и композиции для улучшения когнитивной функции |
| WO2011107530A2 (en) | 2010-03-03 | 2011-09-09 | Probiodrug Ag | Novel inhibitors |
| JP5688745B2 (ja) | 2010-03-10 | 2015-03-25 | プロビオドルグ エージー | グルタミニルシクラーゼ(qc、ec2.3.2.5)の複素環阻害剤 |
| WO2011131748A2 (en) | 2010-04-21 | 2011-10-27 | Probiodrug Ag | Novel inhibitors |
| EP2590696B1 (en) | 2010-07-05 | 2017-03-08 | Gambro Lundia AB | An ambulatory ultrafiltration device, related methods and a computer program product |
| TR201007110A2 (tr) | 2010-08-25 | 2012-03-21 | Bi̇lgi̇ç Mahmut | Sinerjik etki gösteren kombinasyonlar |
| WO2012048871A1 (en) | 2010-10-12 | 2012-04-19 | Merz Pharma Gmbh & Co. Kgaa | Memantine for improving cognitive performance in subjects |
| EP2686313B1 (en) | 2011-03-16 | 2016-02-03 | Probiodrug AG | Benzimidazole derivatives as inhibitors of glutaminyl cyclase |
| FR2983732B1 (fr) * | 2011-12-09 | 2013-11-22 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}pharmaceutiques qui la contiennent |
| WO2013160728A1 (en) * | 2012-04-26 | 2013-10-31 | Alma Mater Studiorum - Universita' Di Bologna | Dual targeting compounds for the treatment of alzheimer's disease |
| WO2014055047A1 (en) * | 2012-08-31 | 2014-04-10 | Mahmut Bilgic | Combination of idebenone and donezepil |
| WO2014035355A1 (en) * | 2012-08-31 | 2014-03-06 | Mahmut Bilgic | Pharmaceutical combination comprising idebenone and memantine |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| GEP201706739B (en) * | 2012-12-13 | 2017-09-25 | H Lundbeck As | Compositions comprising vortioxetine and donepezil |
| AU2014228512A1 (en) | 2013-03-15 | 2015-10-01 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| US10154971B2 (en) | 2013-06-17 | 2018-12-18 | Adamas Pharma, Llc | Methods of administering amantadine |
| CA2986598C (en) | 2015-05-22 | 2023-09-26 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
| JP6629464B2 (ja) * | 2016-05-18 | 2020-01-15 | スヴェン・ライフ・サイエンシズ・リミテッド | 純粋な5−ht6受容体アンタゴニスト、アセチルコリンエステラーゼ阻害剤及びnmda受容体アンタゴニストの3種類の組合せ |
| KR102592614B1 (ko) | 2016-07-25 | 2023-10-24 | 위스타 레보레이토리스 리미티드 | 디아미노페노티아진 (diaminophenothiazines)의 투여 및 투여량 (dosage) |
| GB201614834D0 (en) * | 2016-09-01 | 2016-10-19 | Wista Lab Ltd | Treatment of dementia |
| KR101938872B1 (ko) * | 2016-09-30 | 2019-01-16 | 주식회사 바이오파마티스 | 도네페질 또는 그의 약학적으로 허용 가능한 염 및 메만틴 또는 그의 약학적으로 허용 가능한 염을 함유하는 치매 및 인지기능 장애 예방 또는 치료용 약학 조성물 및 이의 제조방법 |
| US10548855B2 (en) * | 2016-10-28 | 2020-02-04 | Chase Pharmaceuticals Corporation | Memantine combinations and use |
| TR201619184A2 (tr) | 2016-12-22 | 2018-07-23 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Donepezi̇l ve memanti̇n i̇çeren kapsül bi̇leşi̇mleri̇ |
| CA3072764A1 (en) | 2017-08-24 | 2019-02-28 | Adamas Pharma, Llc | Amantadine compositions, preparations thereof, and methods of use |
| ES2812698T3 (es) | 2017-09-29 | 2021-03-18 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
| DK3826639T3 (da) | 2018-07-26 | 2024-09-23 | Wista Lab Ltd | Optimeret dosering af diaminophenothiaziner i populationer |
| PT3843702T (pt) | 2019-05-31 | 2023-10-13 | Tecnimede Soc Tecnico Medicinal Lda | Combinação de dose fixa de libertação imediata de memantina e donepezilo |
-
2003
- 2003-05-22 WO PCT/DK2003/000342 patent/WO2003101458A1/en not_active Ceased
- 2003-05-22 PL PL03373903A patent/PL373903A1/xx not_active Application Discontinuation
- 2003-05-22 IL IL16525503A patent/IL165255A0/xx unknown
- 2003-05-22 NZ NZ536603A patent/NZ536603A/en not_active IP Right Cessation
- 2003-05-22 SI SI200331469T patent/SI1509232T1/sl unknown
- 2003-05-22 JP JP2004508815A patent/JP2005528431A/ja active Pending
- 2003-05-22 EP EP03724895A patent/EP1509232B1/en not_active Revoked
- 2003-05-22 DK DK03724895T patent/DK1509232T3/da active
- 2003-05-22 BR BR0311375-2A patent/BR0311375A/pt not_active IP Right Cessation
- 2003-05-22 ES ES03724895T patent/ES2314200T3/es not_active Expired - Lifetime
- 2003-05-22 AT AT03724895T patent/ATE414519T1/de active
- 2003-05-22 MX MXPA04011762A patent/MXPA04011762A/es active IP Right Grant
- 2003-05-22 PT PT03724895T patent/PT1509232E/pt unknown
- 2003-05-22 DE DE60324788T patent/DE60324788D1/de not_active Expired - Lifetime
- 2003-05-22 AU AU2003227516A patent/AU2003227516B2/en not_active Ceased
-
2004
- 2004-12-13 NO NO20045434A patent/NO332754B1/no not_active IP Right Cessation
-
2009
- 2009-01-21 CY CY20091100080T patent/CY1108725T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO332754B1 (no) | 2013-01-07 |
| MXPA04011762A (es) | 2005-03-31 |
| EP1509232B1 (en) | 2008-11-19 |
| JP2005528431A (ja) | 2005-09-22 |
| DE60324788D1 (de) | 2009-01-02 |
| CY1108725T1 (el) | 2014-04-09 |
| AU2003227516A1 (en) | 2003-12-19 |
| WO2003101458A1 (en) | 2003-12-11 |
| NO20045434L (no) | 2004-12-13 |
| DK1509232T3 (da) | 2009-02-23 |
| PT1509232E (pt) | 2009-01-07 |
| SI1509232T1 (sl) | 2009-04-30 |
| ATE414519T1 (de) | 2008-12-15 |
| AU2003227516B2 (en) | 2008-03-20 |
| ES2314200T3 (es) | 2009-03-16 |
| PL373903A1 (en) | 2005-09-19 |
| IL165255A0 (en) | 2005-12-18 |
| NZ536603A (en) | 2007-06-29 |
| EP1509232A1 (en) | 2005-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 11A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2256 DE 01/04/2014. |