ATE486851T1 - Verfahren zur herstellung von montekulast - Google Patents

Verfahren zur herstellung von montekulast

Info

Publication number: ATE486851T1
Authority: AT; Austria
Prior art keywords: formula; montecuload; producing; reaction; compound
Prior art date: 2007-01-09

Application number

AT08700826T

Other languages

English (en)

Inventor

Ales Halama

Josef Jirman

Original Assignee

Zentiva Ks

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-01-09

Filing date

2008-01-08

Publication date

2010-11-15

2008-01-08 Application filed by Zentiva Ks filed Critical Zentiva Ks

2010-11-15 Application granted granted Critical

2010-11-15 Publication of ATE486851T1 publication Critical patent/ATE486851T1/de

Links

238000004519 manufacturing process Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
UCHDWCPVSPXUMX-TZIWLTJVSA-N Montelukast Chemical compound CC(C)(O)C1=CC=CC=C1CC[C@H](C=1C=C(\C=C\C=2N=C3C=C(Cl)C=CC3=CC=2)C=CC=1)SCC1(CC(O)=O)CC1 UCHDWCPVSPXUMX-TZIWLTJVSA-N 0.000 abstract 1
239000002202 Polyethylene glycol Substances 0.000 abstract 1
239000004721 Polyphenylene oxide Substances 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000003983 crown ethers Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
239000012442 inert solvent Substances 0.000 abstract 1
229960005127 montelukast Drugs 0.000 abstract 1
229920000570 polyether Polymers 0.000 abstract 1
229920001223 polyethylene glycol Polymers 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D323/00—Heterocyclic compounds containing more than two oxygen atoms as the only ring hetero atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Quinoline Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT08700826T 2007-01-09 2008-01-08 Verfahren zur herstellung von montekulast ATE486851T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CZ20070020A CZ302238B6 (cs)	2007-01-09	2007-01-09	Zpusob prípravy montelukastu
PCT/CZ2008/000002 WO2008083635A1 (en)	2007-01-09	2008-01-08	A method for the preparation of montelukast

Publications (1)

Publication Number	Publication Date
ATE486851T1 true ATE486851T1 (de)	2010-11-15

Family

ID=39365931

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT08700826T ATE486851T1 (de)	2007-01-09	2008-01-08	Verfahren zur herstellung von montekulast

Country Status (10)

Country	Link
US (1)	US20100174083A1 (de)
EP (1)	EP2118063B1 (de)
AT (1)	ATE486851T1 (de)
CZ (1)	CZ302238B6 (de)
DE (1)	DE602008003311D1 (de)
EA (1)	EA200900961A1 (de)
ES (1)	ES2354589T3 (de)
PL (1)	PL2118063T3 (de)
UA (1)	UA97511C2 (de)
WO (1)	WO2008083635A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101213177A (zh)	2005-07-05	2008-07-02	特瓦制药工业有限公司	孟鲁司特的纯化
JP6119127B2 (ja) *	2012-06-25	2017-04-26	大日本印刷株式会社	モンテルカストの製造法
JP6162004B2 (ja) *	2013-09-10	2017-07-12	株式会社トクヤマ	モンテルカストナトリウム中間体の分析方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1646612B1 (de) *	2004-04-21	2009-07-01	Teva Pharmaceutical Industries Ltd	Verfahren zur herstellung von montelukast-natrium

2007
- 2007-01-09 CZ CZ20070020A patent/CZ302238B6/cs not_active IP Right Cessation
2008
- 2008-01-08 EA EA200900961A patent/EA200900961A1/ru unknown
- 2008-01-08 ES ES08700826T patent/ES2354589T3/es active Active
- 2008-01-08 DE DE602008003311T patent/DE602008003311D1/de active Active
- 2008-01-08 AT AT08700826T patent/ATE486851T1/de not_active IP Right Cessation
- 2008-01-08 US US12/522,407 patent/US20100174083A1/en not_active Abandoned
- 2008-01-08 WO PCT/CZ2008/000002 patent/WO2008083635A1/en not_active Ceased
- 2008-01-08 PL PL08700826T patent/PL2118063T3/pl unknown
- 2008-01-08 EP EP08700826A patent/EP2118063B1/de not_active Not-in-force
- 2008-01-08 UA UAA200908448A patent/UA97511C2/ru unknown

Also Published As

Publication number	Publication date
ES2354589T3 (es)	2011-03-16
UA97511C2 (ru)	2012-02-27
PL2118063T3 (pl)	2011-04-29
DE602008003311D1 (de)	2010-12-16
WO2008083635B1 (en)	2008-10-09
WO2008083635A1 (en)	2008-07-17
EA200900961A1 (ru)	2010-02-26
CZ302238B6 (cs)	2011-01-05
US20100174083A1 (en)	2010-07-08
EP2118063A1 (de)	2009-11-18
CZ200720A3 (cs)	2009-03-04
EP2118063B1 (de)	2010-11-03

Similar Documents

Publication	Publication Date	Title
RU2010141941A (ru)	2012-04-27	Способ получения фторсодержащего производного ацилуксусной кислоты, способ получения фторсодержащего производного сложного эфира пиразолкарбоновой кислоты и способ получения фторсодержащего пиразолкарбоновой кислоты
WO2008126858A1 (ja)	2008-10-23	アミド化合物の製造方法
MX347564B (es)	2017-05-03	Proceso para la preparacion de n-metoxi-[1-metil-2-feniletil]amida s del acido 3-difluorometil-1-metil-1h-pirazol-4-carboxilico sustituidas con fenilo.
MX2013000288A (es)	2013-05-22	Metodo para fabricar quinolina-3-carboxamidas.
MX2010003148A (es)	2010-04-01	Procedimiento para la preparacion de diamidas de acido sulfonico.
ATE422200T1 (de)	2009-02-15	Verfahren zur herstellung substituierter nikotinsäureester
HK1219727A1 (zh)	2017-04-13	氟代烷基磺酸烷基酯的烷基化
ATE377593T1 (de)	2007-11-15	9,10-alpha,alpha-oh-taxananaloga und verfahren zu deren herstellung
DE602008003311D1 (de)	2010-12-16	Verfahren zur herstellung von montekulast
ATE513801T1 (de)	2011-07-15	Verfahren zur synthese von propargylatierten aminoindanderivativen
MX2013008595A (es)	2013-08-14	Procedimiento mejorado para la preparacion de 2,2-difluoroetilamina.
WO2008123349A1 (ja)	2008-10-16	Ｎ－フェニル－ｎ’－フェニルスルホニルピペラジン誘導体の製造方法
RU2012142223A (ru)	2014-04-10	Пространственно-затрудненные амины
AR048043A1 (es)	2006-03-22	Metodo para producir compuestos de aminifenol
TW200604161A (en)	2006-02-01	Chemical process
MX349740B (es)	2017-08-10	Proceso para la preparacion de fenilpropanonas sustituidas.
ATE378312T1 (de)	2007-11-15	Verfahren zur herstellung von adapalene
TW200504113A (en)	2005-02-01	Curable polycyclic compounds and process for the production thereof
AR051936A1 (es)	2007-02-21	Proceso para la preparacion de pirazoles
TW200736218A (en)	2007-10-01	Method for producing tertiary amines
MY176313A (en)	2020-07-28	Curable composition, curing product, and method for using curable composition
EP2028183A4 (de)	2009-08-19	Neue epoxyverbindung und verfahren zu deren herstellung
ATE353877T1 (de)	2007-03-15	Verfahren zur herstellung von monoifluorierten pyridinyl- und pyrimidinyl-beta-ketoestern
DK1741716T3 (da)	2011-11-28	Fremgangsmåde til fremstilling af pentacyklisk taxan
MY192335A (en)	2022-08-17	Process for preparing 2-exo-(2-methylbenzyloxy)-1-methyl-4-isopropyl-7-oxabicyclo[2.2.1]heptane

Legal Events

Date	Code	Title	Description
2011-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties