ATE486886T1 - Neue betulinsäurederivate kondensiert im a-ring mit einer heterozyklischen gruppe - Google Patents

Neue betulinsäurederivate kondensiert im a-ring mit einer heterozyklischen gruppe

Info

Publication number: ATE486886T1
Authority: AT; Austria
Prior art keywords: alkyl; acid derivatives; betulinic acid; ring; heterocyclic group
Prior art date: 2005-02-09

Application number

AT05850957T

Other languages

English (en)

Inventor

Rama Mukherjee

Sanjay K Srivastava

Mohammad J A Siddiqui

Manu Jaggi

Anu T Singh

Anand Vardhan

Manoj Kumar Singh

Praveen Rajendran

Hemant Kumar Jajoo

Anand C Burman

Vivek Kumar

Nidhi Rani

Shiv Kumar Agarwal

Original Assignee

Dabur Pharma Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-02-09

Filing date

2005-12-29

Publication date

2010-11-15

2005-12-29 Application filed by Dabur Pharma Ltd filed Critical Dabur Pharma Ltd

2010-11-15 Application granted granted Critical

2010-11-15 Publication of ATE486886T1 publication Critical patent/ATE486886T1/de

Links

QGJZLNKBHJESQX-FZFNOLFKSA-N betulinic acid Chemical class C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C(=C)C)[C@@H]5[C@H]4CC[C@@H]3[C@]21C QGJZLNKBHJESQX-FZFNOLFKSA-N 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
206010028980 Neoplasm Diseases 0.000 abstract 2
150000001408 amides Chemical class 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
150000001733 carboxylic acid esters Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only
- C07J71/0047—Nitrogen only at position 2(3)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Analytical Chemistry (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Oncology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT05850957T 2005-02-09 2005-12-29 Neue betulinsäurederivate kondensiert im a-ring mit einer heterozyklischen gruppe ATE486886T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IN265DE2005		2005-02-09
PCT/IN2005/000445 WO2006085334A2 (en)	2005-02-09	2005-12-29	Novel betulinic acid derivatives a-ring-condensed to a heterocyclic group

Publications (1)

Publication Number	Publication Date
ATE486886T1 true ATE486886T1 (de)	2010-11-15

Family

ID=36793451

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05850957T ATE486886T1 (de)	2005-02-09	2005-12-29	Neue betulinsäurederivate kondensiert im a-ring mit einer heterozyklischen gruppe

Country Status (12)

Country	Link
US (1)	US8022055B2 (de)
EP (1)	EP1858910B1 (de)
KR (1)	KR101068259B1 (de)
AT (1)	ATE486886T1 (de)
AU (1)	AU2005327442B2 (de)
BR (1)	BRPI0519948A2 (de)
CA (1)	CA2597300C (de)
DE (1)	DE602005024623D1 (de)
EA (1)	EA013158B1 (de)
NZ (1)	NZ560734A (de)
WO (1)	WO2006085334A2 (de)
ZA (1)	ZA200706393B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9062197B2 (en) *	2009-03-27	2015-06-23	Eastman Chemical Company	Polyester blends
PL227790B1 (pl)	2015-08-13	2018-01-31	Slaski Univ Medyczny W Katowicach	Fosfoniany acetylenowych pochodnych betuliny o działaniu przeciwnowotworowym, sposób ich wytwarzania i zastosowanie.
CA3075729A1 (en)	2017-09-14	2019-03-21	Phoenix Biotechnology, Inc.	Use of oleandrin to treatn viral infection
JP7370966B2 (ja)	2017-09-14	2023-10-30	フェニックス・バイオテクノロジー・インコーポレイテッド	神経学的状態を治療するための方法および改善された神経保護組成物
EP4295854A3 (de)	2020-03-31	2024-04-03	Phoenix Biotechnology, Inc.	Verfahren und zusammensetzungen zur behandlung von coronavirusinfektionen
SG11202105728YA (en)	2020-03-31	2021-11-29	Phoenix Biotechnology Inc	Method and compositions for treating coronavirus infection

2005
- 2005-12-29 EP EP05850957A patent/EP1858910B1/de not_active Expired - Lifetime
- 2005-12-29 WO PCT/IN2005/000445 patent/WO2006085334A2/en not_active Ceased
- 2005-12-29 KR KR1020077019465A patent/KR101068259B1/ko not_active Expired - Fee Related
- 2005-12-29 NZ NZ560734A patent/NZ560734A/en not_active IP Right Cessation
- 2005-12-29 BR BRPI0519948-4A patent/BRPI0519948A2/pt not_active IP Right Cessation
- 2005-12-29 EA EA200701689A patent/EA013158B1/ru not_active IP Right Cessation
- 2005-12-29 US US11/883,753 patent/US8022055B2/en not_active Expired - Fee Related
- 2005-12-29 DE DE602005024623T patent/DE602005024623D1/de not_active Expired - Lifetime
- 2005-12-29 AU AU2005327442A patent/AU2005327442B2/en not_active Ceased
- 2005-12-29 AT AT05850957T patent/ATE486886T1/de not_active IP Right Cessation
- 2005-12-29 CA CA2597300A patent/CA2597300C/en not_active Expired - Fee Related
2007
- 2007-08-01 ZA ZA200706393A patent/ZA200706393B/xx unknown

Also Published As

Publication number	Publication date
ZA200706393B (en)	2009-11-25
US8022055B2 (en)	2011-09-20
CA2597300C (en)	2012-11-27
WO2006085334A2 (en)	2006-08-17
KR101068259B1 (ko)	2011-09-28
EA200701689A1 (ru)	2008-02-28
NZ560734A (en)	2010-09-30
AU2005327442A1 (en)	2006-08-17
AU2005327442B2 (en)	2011-09-01
EP1858910A2 (de)	2007-11-28
EP1858910B1 (de)	2010-11-03
EA013158B1 (ru)	2010-02-26
DE602005024623D1 (de)	2010-12-16
KR20070107717A (ko)	2007-11-07
WO2006085334A3 (en)	2007-06-14
US20080293682A1 (en)	2008-11-27
BRPI0519948A2 (pt)	2009-12-01
CA2597300A1 (en)	2006-08-17

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Legal Events

Date	Code	Title	Description
2011-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties